Clinical trials: Preoperative
Cesarean Section, Pregnancy
Effect of Acupressure on the "Yin-Tang" and "Shen-Men" Points on Pre and Postoperative Anxiety in Elective Caesarean Section: a Prospective, Single-blind, Randomised, Controlled Trial
Preoperative anxiety occurs commonly in elective caesarean section and is associated with increased perioperative morbidity. Some groups have used non-pharmacological techniques such as acupressure for its treatment since drugs…
- Conditions
- Cesarean Section, Pregnancy, Preoperative Anxiety
- Trial name
- ACUCESAR (NCT06119971)
- Testing
- ACUPRESSURE
- Where
- France
- Volunteers
- 44 people
- Sponsor
- University Hospital, Tours
Gall Stones
Preoperative Relaxation and Intensified Patient Surgery Education in Patients Undergoing Cholecystectomy
This study aims to test the effects of a Preoperative Relaxation intervention and an Intensified Surgery Patient Education on pre- and postoperative wellbeing and health in Patients Undergoing Cholecystectomy.
- Trial name
- MBM_Galle (NCT02481271)
- Testing
- relaxation program, surgery education
- Where
- Germany
- Volunteers
- 108 people
- Sponsor
- Universität Duisburg-Essen
Colorectal Cancer
An Observational Study of Xeloda (Capecitabine) and Oxaliplatin Prior and Concurrent To Preoperative Pelvic Radiotherapy in Patients With Locally Advanced Rectal Cancer
This observational study is a follow-up study of protocol ML18280. Survival data of patients who took part in and concluded study ML18280 will be collected for up to 5 years after LPLV of ML18270.
- Trial name
- NCT01339832
- Where
- 5 sites in Switzerland
- Volunteers
- 51 people
- Sponsor
- Hoffmann-La Roche
Complication, Postoperative
Preoperative High Dose Steroids for Liver Resection- Effect on Complications in the Immediate Postoperative Period
Background: Several randomized clinical trials have shown beneficial effects of pre-operative glucocorticoids on post-operative complications.
- Trial name
- STEREO (NCT03403517)
- Testing
- Methylprednisolone, Dexamethasone
- Where
- Denmark
- Volunteers
- 174 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Penicillin Allergy, Surgical Prophylaxis
Impact of Pre-operative Penicillin Allergy Evaluation on Surgical Prophylaxis
Use of first-line pre-operative antibiotic prophylaxis is the most effective measure to optimize perioperative outcomes. However, this is often not achieved due to unsubstantiated penicillin allergy labels.
- Trial name
- NCT05823155
- Testing
- Detailed penicillin allergy evaluation
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- Chinese University of Hong Kong
Cardiovascular Complication
Effect of the Amino Acid L-arginine on Perioperative Cardio-vascular Risk in Non-selected Patients
The aim of the study is to test whether pre-operative oral supplementation with L-arginine results in a significant reduction of peri-operative cardiovascular complication rate in unselected patients undergoing major abdominal or…
- Trial name
- NCT01413815
- Testing
- L-arginine
- Where
- 5 sites in Germany
- Volunteers
- 269 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Pancreas Cancer
Preoperative Stent Study
Randomized study comparing the effect of plastic stents to that of expandable metal stents as pre-operative drainage of the bile ducts prior to Whipple operation.
- Trial name
- NCT00501176
- Testing
- Plastic and metalic stent inserion
- Where
- Sweden
- Volunteers
- 92 people
- Sponsor
- Karolinska Institutet
Cesarean Scar Pregnancy
Effect of Methotrexate on Blood Loss During Laparoscopic Management of CS Scar Pregnancy
Effect of Preoperative Methotrexate on Intraoperative Blood Loss and Surgical Outcomes During Laparoscopic Management of Cesarean Scar Pregnancy: A Prospective Cohort Study.
- Trial name
- CSEP (NCT07886216)
- Volunteers
- 42 people
- Sponsor
- Assiut University
Cancer of Rectum
Preoperative ChemoRadiation And FOLFOXIRI for Rectal Cancer (CRAFTER) for Rectal Cancer
To evaluate the safety and preliminary efficacy of Preoperative ChemoRadiation and FOLFOXIRI and to Escalate Complete Response for Rectal Cancer patients.Go through laboratory and medical tests to verify eligibility to enter the…
- Trial name
- NCT05358704
- Testing
- combination of drugs (chemoradiation (capecitabine and radiation) + FOLFOXIRI (Oxaliplatin, leucovorin, irinotecan, and fluorouracil)
- Where
- 5 sites in United States
- Volunteers
- 38 people
- Sponsor
- Rutgers, The State University of New Jersey
Total Thyroidectomy
Preoperative Hypocalcaemia, a Comparative Clinical Trial
two groups of patients undergoing total thyroidectomy one group received calcium and vit d prophylaxis the other group received no prophylaxis the investigator measured calcium level post and preoperative and development of…
- Trial name
- professor (NCT04212533)
- Testing
- Vitamin D, rice starch tablets
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Zagazig University
Rectal Cancer Stage II, Rectal Cancer Stage III
Optimal Surgery and MRI Based Radiochemotherapy in Rectal Carcinoma
The objective of the study is to provide proof that a MRI based preoperative radiochemotherapy in patients with locally advanced rectal carcinoma allows limiting RCT to high risk patients without increase of locoregional…
- Trial name
- OCUM (NCT01325649)
- Testing
- total mesorectal excision / long course radiochemotherapy, long course 5-FU bases radiochemotherapy
- Where
- Germany
- Volunteers
- 1,051 people
- Sponsor
- Johannes Gutenberg University Mainz
Preoperative Sedation, Postoperative Pain
Preemptive Analgesia for Post Tonsillectomy Pain With IV Morphine in Children
In this double blind study, after taking an informed consent, 60 children aged between 7 and 12 years old assigned for tonsillectomy with or without adenoidectomy will be randomly divided into three groups.
- Trial name
- NCT02995304
- Testing
- Morphine premedication, Midazolam premedication
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Dr. Soliman Fakeeh Hospital
Breast Neoplasms
Preoperative Relaxation Training and Acupuncture to Minimize Perioperative Symptoms in Breast Cancer Patients
Breast cancer surgery is associated with presurgical psychological distress and clinically significant side effects including postsurgical pain, nausea and fatigue.
- Trial name
- NCT02276404
- Testing
- relaxation training, acupuncture
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Universität Duisburg-Essen
Postoperative Pain, Postoperative Nausea and Vomiting
The Effects of Preoperative Physical Activities on Surgeries
Recommendation is strong on physical activity (PA) in the prehabilitation of Enhanced Recovery After Surgery (ERAS) for various types of surgeries. The evidence is however weak regarding ERAS protocols.
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Prehabilitation, Physical Activities
- Trial name
- NCT04739787
- Volunteers
- 5,500 people
- Sponsor
- Chiayi Christian Hospital
Adenocarcinoma of the Pancreas, Stage IA Pancreatic Cancer
RO4929097 Before Surgery in Treating Patients With Pancreatic Cancer
This phase I trial is studying the side effects of RO4929097 before surgery in treating patients with pancreatic cancer. RO4929097 may stop the growth of tumor cells by blocking some enzymes needed for cell growth.
- Conditions
- Adenocarcinoma of the Pancreas, Stage IA Pancreatic Cancer, Stage IB Pancreatic Cancer, Stage IIA Pancreatic Cancer
- Trial name
- NCT01192763
- Testing
- gamma-secretase/Notch signalling pathway inhibitor RO4929097, laboratory biomarker analysis, pharmacological study
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- National Cancer Institute (NCI)
Gastroesophageal Reflux, Esophageal Motility Disorders
High Resolution Manometry After Partial Fundoplication for Gastro-oesophageal Reflux
This is a combined retro- and prospective, monocentric study. All patients who underwent or are planned for laparoscopic partial fundoplication (180° anterior or 270° posterior) between 2020-2023 are assessed for preoperative…
- Conditions
- Gastroesophageal Reflux, Esophageal Motility Disorders, Upper Gastrointestinal Disorder
- Trial name
- NCT05132816
- Testing
- high-resolution manometry
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Prof Urs Zingg
Cubital Tunnel Syndrome
Presence of the Arcade of Struthers on Preoperative Ultrasound
To determine the correlation between the presence of the arcade of Struthers on preoperative ultrasound and during endoscopic surgery for cubital tunnel syndrome, and to determine the reliability of a portable ultrasound probe to…
- Trial name
- NCT04658511
- Testing
- Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Christine M. Kleinert Institute for Hand and Microsurgery
Coronary Artery Disease, Physical Activity
Preoperative Excercise Training for Patients Undergoing Coronary Artery Bypass Graft Surgery
Patients (pts) with stable coronary artery disease (CAD) requiring coronary artery bypass graft surgery (CABG) may be physically inactive during the waiting period to avoid further risks.
- Conditions
- Coronary Artery Disease, Physical Activity, Coronary Artery Bypass Graft Surgery
- Trial name
- NCT04111744
- Testing
- Preoperative Exercise Training, Optimal medical therapy
- Where
- Germany
- Volunteers
- 203 people
- Sponsor
- Kerckhoff Klinik
Breast Cancer
Pre-operative Zoledronate in Triple Negative Breast Cancer
Recent evidences suggest that zoledronate (zol), one of the most used bisphosphonates (BPs) in the clinical setting for the prevention and treatment of bone metastasis in cancer patients, may have antitumor activity in early…
- Trial name
- NCT02347163
- Testing
- Zoledronate
- Where
- 4 sites in Italy
- Volunteers
- 22 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Knee Injuries
Effect of Preoperative MRI Virtual Reality in Patients Undergoing Knee Arthroscope Surgery
Knee MRI is difficult for patients to understand as the image offers a single plane image. Accordingly,investigators sought to transfer the MRI image to 3-dimensional virtual reality system by Mesh rendering technique.
- Trial name
- NCT03426163
- Testing
- Virtual reality
- Where
- South Korea
- Volunteers
- 48 people
- Sponsor
- Hanyang University Seoul Hospital
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