Clinical trials: Preoperative
Colo-rectal Cancer
PREHABILITATION RECTAL CANCER DURING ADJUVANCY VS BEFORE SURGERY
Preoperative preparation protocol (prehabilitation) for patients diagnosed with colorectal cancer who need surgery. It consists of a change in the preoperative preparation.
- Trial name
- prehab-cspt (NCT03543514)
- Testing
- TRIMODAL PREHABILITATION
- Where
- 2 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Corporacion Parc Tauli
Primary Hyperparathyroidism, Primary Hyperparathyroidism Due to Adenoma
Aldosterone Variations in Patients With Primary Hyperparathyroidism After Surgery
Primary hyperparathyroidism is a disorder of calcium and phosphorus metabolism linked to dysfunction of one or more parathyroid glands.
- Trial name
- ALDOPARA2 (NCT07388914)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- Central Hospital, Nancy, France
Hypocalcemia, Thyroid Diseases
Does Preoperative Calcium and Calcitriol Decrease Rates of Post Thyroidectomy Hypocalcemia?
The investigators are performing this study to determine if supplementation with calcium and calcitriol (vitamin D) before surgery decreases the rate of hypocalcemia (low calcium) after surgery.
- Trial name
- NCT03869398
- Testing
- Tums, Calcitriol
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Breast Cancer
Trastuzumab With or Without Everolimus in Treating Women With Breast Cancer That Can Be Removed By Surgery
RATIONALE: Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- NCT00674414
- Testing
- trastuzumab, everolimus, therapeutic conventional surgery
- Where
- 8 sites in France
- Volunteers
- 82 people
- Sponsor
- UNICANCER
Postoperative Anemia, Knee Osteoarthritis
Effect of Preoperative Ferric Carboxymaltose After Simultaneous Bilateral Total Knee Arthroplasty
The primary purpose of this study is to evaluate the safety and efficacy of preoperative intravenous ferric carboxymaltose in patients with anemia undergoing Simultaneous Bilateral Total knee replacement in terms of Quality of…
- Conditions
- Postoperative Anemia, Knee Osteoarthritis, Total Knee Arthroplasty
- Trial name
- NCT03561506
- Testing
- Ferric carboxymaltose, 0.9% Normal Saline
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Anxiety, Pain
Effects of Music on Preoperative Anxiety in Patients With Femoral Fractures Undergoing Surgery
This randomized controlled trial (RCT) investigates the effectiveness of music therapy in reducing preoperative anxiety among elderly patients with femoral fractures.
- Conditions
- Anxiety, Pain, Surgery, Femoral Fractures
- Trial name
- NCT07008482
- Testing
- Music intervention
- Volunteers
- 154 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Rectal Cancer
p53 and Response to Preoperative Radiotherapy for T2 and T3
Background: Meta-analyses of large randomized trials proved the superiority of preoperative short course radiation and surgery, as compared with surgery alone.
- Trial name
- PART1 (NCT02140723)
- Testing
- preoperative short course radiation
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Pancreatic Adenocarcinoma, Poorly Differentiated Malignant Neoplasm
Preoperative Folfirinox for Resectable Pancreatic Adenocarcinoma - A Phase II Study
This phase II trial studies how well combination chemotherapy works in treating patients with pancreatic cancer before undergoing surgery.
- Conditions
- Pancreatic Adenocarcinoma, Poorly Differentiated Malignant Neoplasm, Resectable Pancreatic Cancer, Stage IA Pancreatic Cancer
- Trial name
- NCT02345460
- Testing
- Irinotecan Hydrochloride, Oxaliplatin, Leucovorin Calcium
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Case Comprehensive Cancer Center
Urolithiasis, Ureteral Injury
Effect of Preoperative Alpha-blockers on Successful Insertion Ureteral Access Sheath and Reduce Ureteral Injury in Non-prestented Patients During RIRS. Assessment of Factors for Successful Ureteral Access Sheath Insertion.
The aim of the study is to evaluate the effect of preoperative taking alpha-blockers (tamsulosin or silodosin) on the success rate of ureteral access sheath (UAS) insertion and the degree of ureteral injury during RIRS in…
- Conditions
- Urolithiasis, Ureteral Injury, Ureteral Access Sheath, Retrograde Intrarenal Surgery
- Trial name
- NCT07202923
- Where
- Russia
- Volunteers
- 140 people
- Sponsor
- St. Luke's Clinical Hospital, Russia
Retroperitoneal Soft Tissue Sarcoma
Trial of Neoadjuvant Intensity-Modulated Radiation Therapy Followed by Surgery and Intraoperative Radiation Therapy in Resectable Retroperitoneal Soft Tissue Sarcoma (RETRO-WTS)
Local control rates in patients with retroperitoneal soft tissue sarcoma (RSTS) remain disappointing even after gross total resection, mainly because wide margins are not achievable in the majority of patients.
- Trial name
- NCT01566123
- Testing
- Neoadjuvant intensity-modulated radiation therapy (IMRT), intraoperative radiation therapy (IORT)
- Where
- Germany
- Volunteers
- 37 people
- Sponsor
- University Hospital Heidelberg
Breast Cancer
Preoperative Localisation of the Sentinel Lymph Node in Breast Cancer
When a person has breast cancer it is necessary to find out whether the cancer has spread to the lymph nodes in the armpit because if it has, further treatment is likely to be needed.
- Trial name
- NCT01154972
- Testing
- Preoperative sentinel lymph node identification and marking
- Where
- United Kingdom
- Volunteers
- 59 people
- Sponsor
- NHS Tayside
Heart Diseases
Reducing Intensive Care Unit (ICU) Related Anxiety Through a Structured Information Program
According to current evidence and psychological theorizing, the provision of information seems to be a promising way to reduce the anxiety of patients that is related to their scheduled ICU stay.
- Trial name
- NCT00151554
- Testing
- ICU-specific information program
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Philipps University Marburg
Recurrent Colon Cancer, Recurrent Rectal Cancer
2 Phase Comparison of Pre-operative CT and PET Images for Metastatic Colorectal Cancer
This pilot phase II studies how well computed tomography (CT) and positron emission tomography (PET) imaging works in detecting disease in patients undergoing surgery for metastatic colorectal cancer.
- Conditions
- Recurrent Colon Cancer, Recurrent Rectal Cancer, Stage IV A Bladder Cancer, Stage IV A Rectal Cancer
- Trial name
- NCT01821105
- Testing
- PET Scan, CT Scan, fludeoxyglucose F 18
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Resectable Pancreatic Carcinoma, Stage I Pancreatic Cancer AJCC v6 and v7
Pembrolizumab and Paricalcitol With or Without Chemotherapy in Patients With Pancreatic Cancer That Can Be Removed by Surgery
This phase Ib trial studies the side effects and best way to give pembrolizumab and paricalcitol with or without chemotherapy in patients with pancreatic cancer that can be removed by surgery.
- Conditions
- Resectable Pancreatic Carcinoma, Stage I Pancreatic Cancer AJCC v6 and v7, Stage IA Pancreatic Cancer AJCC v6 and v7, Stage IB Pancreatic Cancer AJCC v6 and v7
- Trial name
- NCT02930902
- Testing
- Gemcitabine Hydrochloride, Laboratory Biomarker Analysis, Nab-paclitaxel
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- M.D. Anderson Cancer Center
Gastric Volume, Ultrasonography
Comparison of Gastric Volume After 6-hour and 8-hour Fasting in Patient Scheduled for Elective Surgery
Preoperative fasting was a common practice to decrease perioperative aspiration risk. Duration of fasting was proportional to gastric volume. Short fasting duration may increase aspiration risk.
- Trial name
- NCT04875845
- Testing
- Fasting for elective surgery
- Where
- Indonesia
- Volunteers
- 37 people
- Sponsor
- Universitas Indonesia
Pulpitis - Irreversible
The Outcome of Preoperative Administration of Single-dose Ketorolac, Non-steroidal Anti-inflammatory Drug and Placebo
Aim. To compare the outcome of preoperative administration of single-dose ketorolac, non-steroidal anti-inflammatory drug and placebo on postoperative pain in teeth with irreversible pulpitis and apical periodontitis.
- Trial name
- PreOp (NCT03116672)
- Testing
- one dose ketorolac 10 mg, One dose Diclofenac
- Where
- Mexico
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Osteomyelitis Chronic, Bone Defects
Pre-Surgery Rehab for a Child With Humeral Head and Shaft Deformity: A Case Report
The goal of this observational study (single-patient case report) is to learn whether a structured pre-operative physical therapy rehabilitation program can improve shoulder function, reduce pain, and improve quality of life in…
- Trial name
- NCT07283302
- Testing
- Transcutaneous Electrical Nerve Stimulation, Low-Level Laser Therapy, Manual Therapy
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Cairo University
Postoperative Pain, Fear
Designing Animated Movie for Preoperative Period
Background: Using visual materials is effective in education to decrease children's pre-operative fear and post-operative pain. Children, especially those aged between 6 and 12 years, are interested in technology.
- Conditions
- Postoperative Pain, Fear, Surgery, Pain
- Trial name
- NCT04176822
- Testing
- Educational animated movie group, Documentary movie group
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Ege University
Dystonia
Predicting DBS Outcomes in Dystonia Using Wearable Gait Sensors
This study aims to investigate whether preoperative gait characteristics, measured by wearable sensors, can predict the clinical outcomes of Deep Brain Stimulation (DBS) in patients with dystonia.
- Trial name
- NCT07323602
- Testing
- Wearable Gait Sensor Analysis
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Ruijin Hospital
Preoperative Fear, Emotional Distress
Comparing Storybooks and Hand Puppets to Reduce Fear in Children Undergoing Day Surgery
Summary The aim of this study is to see if storybooks or hand puppets help reduce fear in children before outpatient surgery. Researchers want to find out which of these two methods works better to help children feel calmer and…
- Trial name
- NCT07430995
- Testing
- Storybook Group, Hand Puppet Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
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