Clinical trials: Preoperative
Cognitive Impairment, Preoperative Cognitive Impairment
Reliability In Neurocognitive Telemedicine Screening (RING)
Perioperative neurocognitive disorders are common after surgery and pre-existing cognitive impairment is an important risk factor.
- Conditions
- Cognitive Impairment, Preoperative Cognitive Impairment, Perioperative Neurocognitive Disorders, Neurocognitive Function
- Trial name
- NCT07760545
- Testing
- Modified Mini-Cog Telephone Assessment
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- University of British Columbia
Obesity & Overweight, Weight Regain
Real-World Tirzepatide Therapy in Post-Bariatric Weight Regain and Preoperative Obesity Patients
This multicenter retrospective observational study evaluates the real-world use of tirzepatide in adult patients with post-bariatric weight regain and in patients with obesity undergoing preoperative management.
- Conditions
- Obesity & Overweight, Weight Regain, Obesity, Morbid
- Trial name
- TIR-REAL (NCT07382180)
- Testing
- Tirzepatide is administered as part of routine clinical care for obesity management, according to standard prescribing practices. Dosing and treatment duration are determined by the treating physician
- Where
- Italy
- Volunteers
- 254 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Impacted Third Molar Tooth
Evaluation of the Effects of Pre-operative Deflazacort on Post-operative Pain, Edema and Trismus
Removal of impacted lower third molar teeth is one of the most common oral surgical procedures, and these operations often lead to various complications in patients.
- Trial name
- NCT04365088
- Testing
- Deflazacort 30 MG Oral Tablet, Sugar pill
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Yuzuncu Yil University
Surgical Skin Preparation
Clinical Evaluation of Patient Preoperative Prep
The objective of the study is to demonstrate the antimicrobial efficacy of the ZP Preoperative Prep on skin flora of the abdomen and inguinal regions of human subjects.
- Trial name
- NCT02831816
- Testing
- ZuraPrep, ChloraPrep, ZP Vehicle
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Zurex Pharma, Inc.
Wound Infection, Breast Neoplasms
Wound Infections in Breast Cancer Surgery After Preoperative Skin Preparation With Chlorhexidine vs. Povidone-iodine
The development of surgical site infections (SSI) in clean-contaminated surgery is regarded as being preventable. Known to be effective in the prevention of surgical site infection are the adequate sterilization of the surgical…
- Trial name
- NCT02479347
- Testing
- Chlorhexidine, Povidone-Iodine
- Where
- Italy
- Volunteers
- 2,158 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Lung Cancer, Solid Pulmonary Nodules
Constructing a Predictive Model for Differentiating Between Benign and Malignant Solid Pulmonary Nodules Based on Clinical and Imaging Features.
Study Objective: To comprehensively analyze the preoperative clinical and imaging characteristics of solid pulmonary nodules, investigate the risk factors associated with malignant solid pulmonary nodules, and provide a reference…
- Conditions
- Lung Cancer, Solid Pulmonary Nodules, Pulmonary Nodules
- Trial name
- NCT06685458
- Testing
- Preoperative Clinical and Imaging Feature Evaluation for Predictive Modeling
- Volunteers
- 320 people
- Sponsor
- The Third Affiliated Hospital of Kunming Medical College.
Prostatectomy, Pelvic Floor Disorders
The Efficacy of Pre-operative Educational Pelvic Floor Intervention on Urinary Continence
Prostate cancer is the most common type of cancer between male population and urinary incontinence (UI) is the most common of long-term sequelae.
- Trial name
- NCT03714984
- Testing
- Pre operative exercise, Control Group
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- European Institute of Oncology
Left Atrial Appendage Thrombosis
The Left Atrial Appendage Closure by Surgery and the Incidence of Stroke in Patients Undergoing Open-heart Surgery.
This study aims to assess the efficacy and safety of prophylactic surgical closure of the left atrial appendage for stroke and cardiovascular death prevention in patients undergoing open heart surgery, regardless of their…
- Trial name
- NCT06172738
- Testing
- the left atrial appendage closure through surgery.
- Volunteers
- 100 people
- Sponsor
- Assiut University
Bleeding
Nasal Desmopressin Versus Oral Bisoprolol for Controlling Bleeding During Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is well established for treatment of chronic rhinosinusitis and nasal polyps. Masking of the surgical field can lead to severe complication as tissue injury, increase post-operative…
- Trial name
- NCT05430048
- Testing
- nasal Desmopressin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Zagazig University
ACL Reconstruction (ACLR) With a Bone-patellar Tendon-bone (BPTB) Autograft
Cryoneurolysis in Anterior Cruciate Ligament Reconstruction (ACLR)
The purpose of this research study is to assess whether cryoneurolysis will help control pain after ACLR surgery and decrease the need of opioid medications.
- Trial name
- NCT07731178
- Testing
- Pacira Iovera Cryoneurolysis device
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Circumlocution, Children
Intelligent Customer-driven Solution for Pediatric Surgery Care for Parents and Their Children Undergoing Circumcision
This study aims to (1) develop an intelligent customer-driven solution for pediatric surgery care for parents of children undergoing circumcision and their children; (2) examine the effectiveness of the intervention on outcomes…
- Conditions
- Circumlocution, Children, Surgery, Parents
- Trial name
- NCT04174404
- Testing
- ICory-Circumcision, Routine care
- Where
- Singapore
- Volunteers
- 160 people
- Sponsor
- HE Hong-Gu
Breast Cancer
Digital Mammography for the Detection and Preoperative Staging of Breast Cancer
Breast tumors are normally seen with mammography or ultrasound without the use of a dye but the size and extent of the tumor may be hard to see.
- Trial name
- NCT01086514
- Testing
- Dual Energy Contrast Enhanced Digital Mammography (DE CEDM)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Surgical Site Infections
The Skin Prep Study
The investigators propose a randomized controlled clinical trial to determine the comparative effectiveness of chlorhexidine-alcohol and iodine-alcohol preoperative skin preparation for preventing surgical site infections at…
- Trial name
- NCT01472549
- Testing
- Iodine-alcohol, Chlorhexidine-alcohol
- Where
- United States
- Volunteers
- 1,147 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Periprosthetic Joint Infection (PJI), Malnutitrion
Impact of Nutritional Status Before Joint Replacement on Infection Risk
Periprosthetic joint infection (PJI) is a serious complication after joint replacement surgery and is difficult to treat. Poor nutritional status may impair the body's ability to recover and fight infection, as well as increase…
- Conditions
- Periprosthetic Joint Infection (PJI), Malnutitrion, Postoperative Complication
- Trial name
- CONUT (Control (NCT07884006)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Pain, Postoperative, ACL Injury
Effectiveness of iPACK on Postoperative Pain From Hamstring Autograft Following ACL Repair
Patients undergoing ACL repair with hamstring autograft frequently develop significant post operative pain at the hamstring grafting site.
- Conditions
- Pain, Postoperative, ACL Injury, Anesthesia, Local, Opioid Use
- Trial name
- NCT05080348
- Testing
- Ropivacaine iPACK Injection, Normal Saline iPACK Injection
- Volunteers
- 40 people
- Sponsor
- Brenton Alexander
Cognitive Change
Preoperative Risk Factors and Perioperative Neurocognitive Disorders
Perioperative neurocognitive disorders (PND's) remain an important complication after surgery. After many years of speculating about the etiology of this complication, currently studies are pointing to an inflammatory cascade…
- Trial name
- NCT03805685
- Testing
- Non-Cardiac Surgery
- Where
- Belgium
- Volunteers
- 38 people
- Sponsor
- Université Libre de Bruxelles
Breast Cancer
The Impact of Preoperative Breast MRI in Patients With Breast Cancer Selected for Breast Conserving Surgery
The purpose of this prospective observational study is to evaluate the impact of preoperative breast MRI in patients with breast cancer selected for breast- conserving surgery.
- Trial name
- NCT01391806
- Where
- Norway
- Volunteers
- 145 people
- Sponsor
- Nordlandssykehuset HF
Colorectal Cancer
Preoperative Valproic Acid and Radiation Therapy for Rectal Cancer
The purpose of this study is to first determine the maximum tolerated dose of capecitabine given alone or in combination with valproic acid during preoperative short-course radiotherapy (Phase 1).
- Trial name
- V-shoRT-R3 (NCT01898104)
- Testing
- preoperative radiation therapy, Valproic Acid, Capecitabine
- Where
- Italy
- Volunteers
- 152 people
- Sponsor
- National Cancer Institute, Naples
Complications Due to Coronary Artery Bypass Graft
Effects of Segmental Breathing Exercise in Patients Awaiting Coronary Artery Bypass Graft Surgery (CABG)
To determine the effects of preoperative segmental breathing exercise on postoperative pulmonary complications in patients awaiting coronary artery bypass graft surgery (CABG). This study will be a randomized controlled trial.
- Trial name
- NCT05585138
- Testing
- segmental breathing exercise, deep breathing
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Propionibacterium
Does Preoperative Administration of Oral Doxycycline Decrease the Colonization Rate of Propionibacterium Acnes in the Dermis of the Shoulder?
The purpose of this study is to evaluate the ability of oral doxycycline to decrease the colonization of Propionibacterium acnes in the dermis of the shoulder.
- Trial name
- NCT02688738
- Testing
- Doxycycline
- Sponsor
- Rothman Institute Orthopaedics
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.