Clinical trials: Preoperative
Tonsillectomy, Adenoidectomy
Modified Pre-operative Oral Doses Acetaminophen Versus Intravenous Acetaminophen
Acetaminophen is frequently used as an adjunct for pain management in pediatric surgical patients. The drug is available in an over the counter, inexpensive oral form as well as a considerably more expensive intravenous form.
- Trial name
- MODIV-APAP (NCT02994940)
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- University of California, Davis
Breast Cancer, Cancer of the Breast
Comparing Letrozole Given Alone to Letrozole Given With Avastin in Post-Menopausal Women Breast Cancer
This purpose of this trial is to show that the combination of Avastin and hormone therapy should be more effective than hormone therapy alone for the treatment of breast cancer.
- Conditions
- Breast Cancer, Cancer of the Breast, Breast Neoplasm
- Trial name
- NCT00530868
- Testing
- Letrozole (Femara), Letrozole; Avastin
- Where
- 7 sites in United States
- Volunteers
- 75 people
- Sponsor
- University of Alabama at Birmingham
Adolescence Idiopathic Scoliosis, Preoperative Anxiety
the Effect of the Preoperative Information Method on Intraoperative Anxiety and Postoperative Outcomes in AIS Patients: a Randomized Clinical Trial
Due to the increasing use of smartphones and social media in contemporary times, adolescents experience a rapid loss of attention while reading or listening.
- Conditions
- Adolescence Idiopathic Scoliosis, Preoperative Anxiety, Postoperative Pain After Spinal Surgery
- Trial name
- NCT07902674
- Testing
- İntervention 1: Video-Based Preoperative Education, İntervention 2: Brochure-Based Preoperative Education, Routine Verbal Preoperative Counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Gazi University
Differentiated Thyroid Carcinoma, Papillary Thyroid Carcinoma
Bethesda Classification and Risk Stratification in Differentiated Thyroid Carcinoma
This observational study aims to evaluate the relationship between preoperative Bethesda classification of fine-needle aspiration cytology and postoperative American Thyroid Association (ATA) risk stratification in patients with…
- Conditions
- Differentiated Thyroid Carcinoma, Papillary Thyroid Carcinoma, Follicular Thyroid Carcinoma
- Trial name
- NCT07858097
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gastric Cancer, Prehabilitation
Preoperative Home-based Multimodal Prehabilitation Based on 5G + Artificial Intelligence Mobile Health
The goal of this prospective, multicenter, open-label randomized controlled clinical trial is to evaluate whether a home-based, digitally supervised multi-modal prehabilitation intervention can improve functional capacity…
- Trial name
- NCT07755917
- Testing
- mHealth prehabilitation group, ERAS group
- Volunteers
- 490 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Rotator Cuff Tears of the Shoulder
Acne Face Wash for Reducing the Contamination Rate in Arthroscopic Rotator Cuff Repair Surgery
Previous studies have shown that even when following standard sterilization protocols, the positive culture rate of Cutibacterium acnes can still be as high as 30%.
- Trial name
- NCT07239349
- Testing
- Acne face wash
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Bariatric Surgery Candidate, Obesity
A Preoperative Cognitive Behavioural Therapy Program Based on Self-determination Theory for Bariatric Surgery Candidates
The objective of this study is to evaluate the impact of a pre-surgical intervention program based on Cognitive and Behavioural Emotional Therapies, on the degree of dietary restriction of patients who are candidates for…
- Trial name
- ACRoBAT (NCT03976674)
- Testing
- Cognitive Behavioural Therapy (CBT)
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Lille Catholic University
Pre-operative Anxiety
The Effect of Laughter Yoga on Preoperative Anxiety in Pediatric Patients
The effect of laughter yoga on a child's pre-operative anxiety.
- Trial name
- NCT07577024
- Testing
- laughter therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Arteriovenous Fistula
Pre-Operative Forearm Exercise On Arteriovenous Fistula Mauration
To investigate the effect of pre-operative exercise on 1. Hemodynamics in the fistula artery and vein, pre and post AV fistula formation 2. Suitability of cannulation of AV fistula at 8weeks
- Trial name
- NCT03137680
- Testing
- Hand Exercise
- Volunteers
- 40 people
- Sponsor
- Changi General Hospital
Head and Neck Cancer
A Phase II Study to Evaluate the Efficacy and Safety of Salvage Preoperative PD-1 Inhibitor Combined with Chemotherapy Neoadjuvant Therapy in Recurrent and Metastatic LPSCC/HPSCC
A prospective, multicenter, randomized controlled phase II study; Patients who met the inclusion criteria were divided into groups according to whether they had received radical radiotherapy or postoperative radiotherapy in the…
- Trial name
- NCT06793761
- Testing
- Pembrolizumab, Cisplatin, Nab-paclitaxel
- Volunteers
- 260 people
- Sponsor
- Beijing Tongren Hospital
Renal Failure Chronic, Surgery
Laparoscopic Donor Nephrectomy Score, a New Scoring System for Preoperative Prediction of Difficulty of Laparoscopic Donor Nephrectomy
The goal of this multicenter observational study is to develope and validate a new scoring system for preoperative prediction of difficulty of Laparoscopic Donor Nephrectomy. Healthy living kidney donors will be enrolled.
- Trial name
- LAPDOCTOR (NCT05769686)
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jacopo Romagnoli
Liver Metastases, Liver Metastasis Colon Cancer
DNX-2440 for Resectable Colorectal Liver Metastasis
The purpose of this study is to test an experimental oncolytic adenovirus called DNX-2440 in patients with resectable multifocal (≥ 2 lesions) liver metastasis, who are scheduled to have curative-intent liver resection surgery.
- Conditions
- Liver Metastases, Liver Metastasis Colon Cancer, Colorectal Cancer, Breast Cancer
- Trial name
- NCT04714983
- Testing
- DNX-2440
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- DNAtrix, Inc.
Symptomatic Irreversible Pulpitis (SIP), Postoperative Pain After Endodontic Treatment
A Randomized Controlled Trial Evaluating Whether Pre-operative Trinase Reduces Post-operative Pain in Patients With Symptomatic Irreversible Pulpitis Compared to Placebo, Using VAS Scores and Analgesic Intake Over 48 Hours.
This study aims to determine whether Trinase, an enzyme-based anti-inflammatory medication, can reduce pain after root canal treatment in patients with symptomatic irreversible pulpitis.
- Conditions
- Symptomatic Irreversible Pulpitis (SIP), Postoperative Pain After Endodontic Treatment, Endodontic Disease, Dental Pain
- Trial name
- NCT07239505
- Testing
- Trinase
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Fayoum University
Spine Surgery
Preoperative Prevention and Early Rehabilitation for Patients Undergoing Elective Spine Surgery
Aim: The aim is to evaluate the outcome after spine surgery when using an integrated program that combined preoperative prevention and early postoperative rehabilitation compared to the routine procedures.
- Trial name
- NCT00459966
- Testing
- Preoperative rehabilitation
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Postoperative Infection
Povidone-iodine Versus Normal Saline Solution in Vaginal Cleansing in Laparoscopy
Laparoscopy is a minimally invasive method used for diagnostic and therapeutic purposes. It allows surgeons to take a look on the abdominal and pelvic organs.
- Trial name
- NCT02591251
- Testing
- Povidone-iodine solution, Normal saline solution
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Anxiety, Surgery
Pre-operative Consultation on Patient Anxiety and First-time Mohs Micrographic Surgery
To determine if in-office pre-operative consultation has a significant effect on the anxiety level and overall post-operative satisfaction of patients undergoing first time Mohs surgery
- Trial name
- NCT04612491
- Testing
- Pre-operative Consultation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of California, Davis
Distal Urethral Cancer, Proximal Urethral Cancer
Gemcitabine Hydrochloride and Cisplatin Before Surgery in Treating Patients With Muscle Invasive Bladder Cancer
The purpose of this research study is to find out what effects, good and/or bad, dose-dense (every 14 days) chemotherapy with gemcitabine (gemcitabine hydrochloride) and cisplatin given before surgery have on patients and their…
- Conditions
- Distal Urethral Cancer, Proximal Urethral Cancer, Squamous Cell Carcinoma of the Bladder, Stage II Bladder Cancer
- Trial name
- NCT01611662
- Testing
- gemcitabine hydrochloride, cisplatin, therapeutic conventional surgery
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- Fox Chase Cancer Center
Anemia
Anemia in Orthopedic Surgery - Determination of Hb
Anemia prevalence in orthopedic surgery is up to 30 %. Identifying those patients prior to surgery and treating them would be ideal. Different ways of determining hemoglobin Levels are available.
- Trial name
- NCT03328780
- Testing
- Hemocue and Rad-67 measurement
- Where
- Switzerland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Theusinger Oliver M.
Menstrual Cycle, Perioperative Hypertension
Effects of Menstrual Cycle on Preoperative Anxiety
The investigators aimed to investigate the effect of menstrual cycle phases on preoperative anxiety in women under general anesthesia.
- Conditions
- Menstrual Cycle, Perioperative Hypertension, Anxiety
- Trial name
- NCT03708679
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Yuzuncu Yil University
Liver Fibrosis, Liver Cirrhosis
Influence of Probiotics Administration Before Liver Resection in Liver Disease
Surgical resection is one of the curative treatment modalities for HCC. Limits are postoperative septic and liver functional complications related to an increase in bacterial translocation and systemic endotoxemia.
- Conditions
- Liver Fibrosis, Liver Cirrhosis, Permeability; Increased, Hepatocellular Carcinoma
- Trial name
- LIPROCES (NCT02021253)
- Testing
- Probiotic
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Rouen
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