Clinical trials: Preoperative
Perioperative Nursing
Effects of Preparing Parents To Participate In Their Child's Care In The Recovery Room
The objectives of this study were to evaluate the effect of a preoperative educational DVD on parents' knowledge acquisition, participation and anxiety related to their child's care in the recovery room (RR).
- Trial name
- NCT02766452
- Testing
- "You and your child in the recovery room" DVD, Standard pre-operative preparation
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Epilepsy
Preoperative Speech Rehabilitation in Drug-Resistant Temporal Epilepsy: A Case Study
Out of 30,000 new cases per year in France, 30% of epileptic patients are drug-resistant. Neurosurgery, which consists in resecting the epileptogenic zone, is the only chance of cure.
- Trial name
- REPREO SCED (NCT05325047)
- Testing
- Intensive speech rehabilitation
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Rectum Cancer
Neoadjuvant FOLFIRINOX and Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer Patients
A phase II clinical trial compared standard TNT (mFolfox6 and CRT) with preoperative chemoradiotherapy (CRT) with neoadjuvant chemotherapy (CT) containing mFolfirinox in patients with locally advanced rectal cancer.
- Trial name
- NCT06812728
- Testing
- mFOLFIRINOX, mFolfox6
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Acute Appendicitis, Acute Appendicitis Without Peritonitis
The Role of Preoperative HALP Score in Differentiating Complicated Acute Appendicitis
Acute abdomen is a frequently encountered clinical condition that can be fatal if not diagnosed early. Acute appendicitis is one of the causes of acute abdomen and is the most common clinical condition leading to acute abdomen…
- Conditions
- Acute Appendicitis, Acute Appendicitis Without Peritonitis, Acute Appendicitis With Appendix Abscess, Acute Appendicitis With Rupture
- Trial name
- Appendicitis (NCT07002671)
- Testing
- Appendectomy, blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 411 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Knee Replacement, Knee Replacement Surgery
Effect of Virtual Reality on Patient Outcomes and Satisfaction in Total Knee Replacement
This study aims to evaluate the effectiveness of virtual reality (VR) in managing preoperative anxiety and postoperative pain in patients undergoing total knee replacement.
- Conditions
- Knee Replacement, Knee Replacement Surgery, Postoperative Pain, Acute, Anxiety, Preoperative
- Trial name
- NCT06933732
- Testing
- Virtual Reality Intervention for Preoperative Anxiety and Postoperative Pain Management (2 hours), Device: Virtual Reality Intervention for Preoperative Anxiety and Postoperative Pain Management (4 hours), Virtual Reality Intervention for Preoperative Anxiety and Postoperative Pain Management (6 hours)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Aykut Turgut
Early Stage Breast Cancer
Impact of Breast Magnetic Resonance Imaging (MRI) on Mastectomy Rates
The primary goal of this study is to determine if preoperative breast MRI findings resulted in more extensive surgery, i.e., mastectomy than breast conserving surgery, i.e., lumpectomy in early stage breast cancers at Summa Akron…
- Trial name
- NCT01166581
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Summa Health System
Intrahepatic Cholangiocarcinoma (Icc)
A Study on Intratumoral Fibrosis and α-SMA Expression in Intrahepatic Cholangiocarcinoma
The aim of this observational study was to understand the prognostic imaging of the degree of intratumoral fibrosis and intratumoral α-SMA levels in patients with intrahepatic cholangiocarcinoma (ICC).
- Trial name
- NCT07479264
- Testing
- No Interventions
- Where
- China
- Volunteers
- 169 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Femur Fracture
Skeletal Versus Cutaneous Traction For Treatment of Femur Fractures
The purpose of this study is to determine whether there are any differences in skeletal or cutaneous traction for the treatment of femur fractures.
- Trial name
- NCT00916136
- Testing
- Femoral Traction
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Vanderbilt University Medical Center
Risk Malignant Index
Risk of Malignancy Index and Assiut Scoring Model for Adnexal Malignancy
The presence of an adnexal mass is a frequent reason for a woman to be referred to a gynaecologist. The discrimination between benign and malignant adnexal masses is central to decisions regarding clinical management and surgical…
- Trial name
- NCT03404687
- Testing
- ultrasound, cancer antigen 125 level, Doppler
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Assiut University
Anesthesia, General
Factors Influencing Anesthetic Drug Requirement
The main objective of the study is to analyze the influence of several environmental (i.e., timing: seasonal, circadian) and demographic conditions (i.e., age, gender, menstrual cycle) on anesthetic drug requirements (hypnotic…
- Trial name
- PosoAnes (NCT00896714)
- Testing
- Closed loop anesthesia
- Where
- 4 sites in France
- Volunteers
- 3,278 people
- Sponsor
- Hopital Foch
Liver Diseases
Preoperative Evaluation of the Remaining Part of the Liver for Liver Resection
Review the outcomes of the current treatments modalities. Give an effective treatment . Improve the outcome of these patients and decease rate of recurrence and complications.
- Trial name
- NCT04100304
- Testing
- resection
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Non Small Cell Lung Cancer
Pembrolizumab With and Without Radiotherapy for Non-Small Cell Lung Cancer
This is a randomized single-institution, phase II, open-label clinical trial of neoadjuvant pembrolizumab with or without low-dose stereotactic radiation therapy (SRT) in stage I-IIIA non-small lung cancer (NSCLC) patients who…
- Trial name
- NCT03217071
- Testing
- Pembrolizumab, stereotactic radiation therapy (SRT), Surgery (Non-interventional, standard of care)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Sue Yom
Prostatic Diseases, Genital Neoplasms, Male
A Study of Ixabepilone Before Surgery for High-Risk Localized Prostate Cancer
The purpose of this research study is to determine the safety and effectiveness of the investigational drug, Ixabepilone, in men with high risk prostate cancer who plan to receive surgery.
- Conditions
- Prostatic Diseases, Genital Neoplasms, Male, Urogenital Neoplasms, Genital Diseases, Male
- Trial name
- NCT00672009
- Testing
- Ixabepilone
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Cedars-Sinai Medical Center
Gastric Adenocarcinoma, Esophageal Adenocarcinoma
Neoadjuvant Intra-tumoral RP2 and FLOT in Gastroesophageal Adenocarcinoma
The research study is being conducted to study whether performing injections of a new treatment, called RP2, directly into stomach and esophagus tumors along with standard chemotherapy (called FLOT) is safe and whether it does a…
- Conditions
- Gastric Adenocarcinoma, Esophageal Adenocarcinoma, Gastroesophageal Junction Adenocarcinoma
- Trial name
- NCT07059611
- Testing
- RP2, 5-Fluorouracil, Leucovorin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Prehabilitation, Pancreas Cancer
Preoperative Optimisation of Modifiable Risk Factors in Surgery of the Pancreas
The goal of this stepped-wedge randomized controlled trial is to investigate whether implementation of a best practice program for preoperative optimisation (prehabilitation program) with a focus on screening, assessment, and…
- Conditions
- Prehabilitation, Pancreas Cancer, Surgery, Postoperative Complications
- Trial name
- PROMISE-P (NCT05851534)
- Testing
- Preoperative optimisation program
- Where
- 13 sites in Netherlands
- Volunteers
- 2,575 people
- Sponsor
- Maastricht University Medical Center
Mammoplasty Patient
Evaluation of Perforator Phase Contrast Angiography in Developing Surgery Plans for Patients With Breast Cancer Undergoing Breast Reconstruction With Free-Flap Methods After Mastectomy
This phase II trial studies how well an imaging technique called perforator phase contrast angiography (pPCA) works in developing surgery plans for patients with breast cancer undergoing breast reconstruction after breast removal…
- Trial name
- NCT04063410
- Testing
- Angiography, MRI-Based Angiogram, Quality-of-Life Assessment
- Where
- United States
- Sponsor
- University of Cincinnati
Hypotension, Geriatric Patients
Preoperative Ultrasonographic Evaluation of Caval Aorta Diameter Index
General anesthesia is frequently used in daily clinical practice. Elderly patients often require a higher level of care than younger patients during the perioperative period, with higher health care costs.
- Conditions
- Hypotension, Geriatric Patients, Anesthesia
- Trial name
- NCT06155461
- Testing
- Preoperative Ultrasonographic Evaluation of Caval Aorta Diameter Index
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Egymedicalpedia
Parathyroid Disease
Relationship of Preoperative Parathyroid Hormone (PTH) and Ex-Vivo Gamma Counts in Minimally Invasive Parathyroidectomy
The intent for this study is to do a retrospective chart review of all patients who have undergone minimally invasive parathyroidectomy for primary hyperthyroidism.
- Trial name
- NCT01539486
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Arkansas
Cleft Lip and Palate
Evaluation of the Effects of LUNII on Pre-operative Anxiety and on the Post-operative Period in Children With Cleft Lip and Palate Admitted for Alveolar Bone Graft: Pilot Study
The literature on the effects of various devices on per-operative anxiety is scarce. There is currently no study on the effects of an interactive storyteller on per-operative anxiety in pediatric surgery.
- Trial name
- LUNII (NCT03740841)
- Testing
- Interactive story teller LUNII
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preoperative Anxiety
Lavender Oil on Preoperative Anxiety and Sedation Requirement in General Anaesthesia
Assessment of how Lavender oil reduces preoperative anxiety and subsequently influences requirement of induction agents for general anesthesia.
- Trial name
- NCT03460145
- Testing
- Lavender Oil on Nasal Strip (Lx), Strip without Lavender Oil (Px), Propofol 1 % Injectable Suspension
- Where
- Malaysia
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
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