Clinical trials: Preoperative
Surgery, Surgical Site Infection
Efficacy of an Intervention to Improve the Preoperative Shower in Scheduled Surgery
The aim of the project is to evaluate the effectiveness, on the skin cleanliness of the patient on arrival at the operating room, of an intervention aimed at improving the performance of the preoperative shower, for patients…
- Trial name
- PRODOUCH'OP (NCT04820075)
- Testing
- improvement of preoperative shower
- Where
- France
- Volunteers
- 22 people
- Sponsor
- University Hospital, Rouen
Rectal Adenocarcinoma
Interest of Saline MR Peritoneography for Pre-operative Assessment of Rectal Cancer
MR saline peritoneography could be useful to demonstrate the peritoneal outline of the pouch of Douglas. The investigators think that the localization of the rectal tumor in function of this anatomic mark could be decisive for…
- Trial name
- NCT01497457
- Testing
- MR saline peritoneography
- Where
- Belgium
- Volunteers
- 17 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Cardiopulmonary Bypass
Does Sildenafil Protect Against Pulmonary Related Complications Following Cardiopulmonary Bypass?
Does pre-operative administration of Sildenafil (Viagra, Pfizer) reduce the lung injury associated with cardiopulmonary bypass in children undergoing corrective surgical repair of congenital heart disease.
- Trial name
- NCT00350441
- Testing
- Sildenafil Citrate
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- NHS Greater Glasgow Yorkhill Division
Cardiac Surgery, Congenital Heart Disease
Influence of Preop Fibrinogen on Blood in Pediatric Cardiac Surgery
Fibrinogen plays an important role in the coagulation cascade. Low levels of preoperative fibrinogen have been associated in adults with higher blood and transfusion requirements during surgery.
- Conditions
- Cardiac Surgery, Congenital Heart Disease, Cardiopulmonary Bypass, Fibrinogenemia
- Trial name
- NCT05525195
- Testing
- Congenital cardiac surgery
- Where
- Belgium
- Volunteers
- 932 people
- Sponsor
- Brugmann University Hospital
Music Therapy, Anxiety
Therapy on Perioperative Anxiety and Pain in Patients
This study aims to explore the effects of preoperative education combined with intraoperative music therapy on perioperative anxiety and pain in patients undergoing elective cesarean section.
- Conditions
- Music Therapy, Anxiety, Health Education
- Trial name
- NCT06970431
- Testing
- eoperative Education + Intraoperative Music Therapy Arm, Preoperative Education Alone Arm
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Reduction in Bacterial Counts Through the Use of Mouthwash
Dental Implants and Mouth Rinse
The primary aim of this study is to evaluate and compare the efficacy of a 60 second rinse with chlorhexidine, essential oil-based mouthwash, cetylpyridinium chloride mouthwash, or saline solution on bacterial contamination in…
- Trial name
- NCT02002442
- Testing
- Mouthwash
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tufts University
Postoperative Delirium
Effects of Different Preoperative Oral Rehydration Protocols in Undergoing Thoracoscopic Radical Lung Cancer Surgery
This study aims to compare the new preoperative oral rehydration protocol (administering 50-100 mL of clear fluids or carbohydrate-rich beverages orally every hour until the patient arrives at the operating room) with the…
- Trial name
- NCT07042503
- Volunteers
- 420 people
- Sponsor
- Fujian Medical University Union Hospital
Anterior Cruciate Ligament Rupture
Effect of Preoperative Exercise Habits on Knee Function and Recurrence Rate After Anterior Cruciate Ligament Reconstruction
The aim of this study is to compare the knee function between patients with and without preoperative exercise habits at 1, 2 and 5 years after ACL surgery, and further analyze the effect of maintaining exercise habits on knee…
- Trial name
- NCT06608394
- Testing
- no intervention
- Where
- China
- Volunteers
- 361 people
- Sponsor
- Peking University Third Hospital
Unresectable Gallbladder Cancer
A Clinical Study of a Preoperative Translational Therapy for Unresectable Gallbladder Cancer
This is an open-label,multicenter ,non-randomized,single arm exploratory study. The objective of this study is to evaluate the efficacy and safety of PD-1 antibody plus GEMOX as preoperative translational therapy for unresectable…
- Trial name
- NCT05919095
- Testing
- Carrilizumab plus GEMOX
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Ligament Injury, Ligament Rupture
Knee Functionality Recovery Indicators in Athletes Submitted to Ligamentoplasty of the Anterior Cruciate Ligament
Anterior cruciate ligament (ACL) injuries are recurrent, especially in sports. There is still no consensus on the characterization of functional indicators in this clinical condition, as well as their correlation with measuring…
- Conditions
- Ligament Injury, Ligament Rupture, Ligament Disorders
- Trial name
- NCT06050005
- Testing
- Diagnostic test through functional tests and comparison of scales applied to participants in the pre-surgical and post-surgical period.
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Gastroscopy
Evaluation of Gastric Volume and pH Changes in Gastroscopy Patients
Pulmonary aspiration is a rare but serious complication that can result in 57% mortality and 14% permanent damage. Fasting rules (solid foods 6-8 hours, clear liquids 2 hours) determined by anesthesia associations are applied to…
- Trial name
- NCT06842602
- Testing
- gum, candy, strict fasting rules
- Where
- Turkey (Türkiye)
- Volunteers
- 405 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Breast Cancer
Randomized Study of Combination Chemotherapy With or Without Focused Microwave Thermotherapy Before Surgery in Treating Women With Large Breast Cancer Tumors
The purpose of this randomized Phase III study is to determine whether preoperative focused microwave heat treatment and chemotherapy combined are more effective than preoperative chemotherapy alone in the treatment of large…
- Trial name
- Medifocus301 (NCT01204801)
- Testing
- Focused Microwave Thermotherapy, Chemotherapy (control)
- Where
- 2 sites in United States, Canada
- Volunteers
- 238 people
- Sponsor
- Medifocus, Inc.
Soft Tissue Sarcoma
5-Day Preoperative Radiation for Soft Tissue Sarcoma
The purpose of this study is to examine the safety and efficacy of an abbreviated course of preoperative radiation, given over five days, for patients with soft tissue sarcoma of the extremity, trunk or retroperitoneum.
- Trial name
- NCT06087861
- Testing
- External Beam Radiotherapy
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Stanford University
Lung Hydatid Cyst
The Importance of Inflammatory Markers Calculated From Preoperative and Postoperative Peripheral Blood Results in the Diagnosis and Treatment of Patients Operated for Hydatid Cyst of the Lung (Lung Echinococcus Granulosus)
This study aims to investigate the role of these laboratory findings in the differential diagnosis and management of pulmonary hydatid cyst (PHC) by examining the number of euzonophils, neutrophils, lymphocytes, platelets and…
- Trial name
- Echinococcusis (NCT06281522)
- Testing
- Operated patients with hydatid cyst of the lung
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Abdullah Adiyaman
Burns, Frailty
Frailty Index and Mortality After a Burn Surgery
Frailty is a condition of a reduced physiological reserve and is associated with postoperative morbidity and mortality. We evaluated the impact of preoperative frailty index (CFI) on 90-day mortality after a burn surgery.
- Trial name
- NCT05613829
- Testing
- Burn surgery
- Where
- South Korea
- Volunteers
- 1,118 people
- Sponsor
- Asan Medical Center
Developmental Dysplasia of the Hip
AI-assisted Preoperative Planning Technology for THA for DDH
In this study, the investigators retrospectively collected DDH case data of THA assisted by AI 3D planning and THA assisted by traditional planning.
- Trial name
- NCT05929105
- Testing
- artificial intelligence (AI)-assisted three-dimensional preoperative planning technology, X-ray film template for 2D planning
- Where
- China
- Volunteers
- 61 people
- Sponsor
- General Hospital of Ningxia Medical University
Early Breast Cancer
Radiotherapy in Preoperative Setting With CyberKnife for Breast Cancer
The aim of this study is to prospectively evaluate, in patients affected by early breast cancer, safety and feasibility of single fraction radiotherapy with Cyberknife R in preoperative setting, and to identify factors predictive…
- Trial name
- ROCK (NCT03520894)
- Testing
- Neoadjuvant radiotherapy
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Colorectal Cancer
Neoadjuvant Radiation Therapy and Capecitabine in Treating Patients With Stage III or Stage IV Colorectal Adenocarcinoma
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy, such as capecitabine, use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00075556
- Testing
- capecitabine, conventional surgery, neoadjuvant therapy
- Where
- 12 sites in France
- Sponsor
- GERCOR - Multidisciplinary Oncology Cooperative Group
Blood Transfusion, Blood Transfusion, Autologous
A Study to Determine the Safety and Effectiveness of Epoetin Alfa in Facilitating Self-donation of Blood Before Surgery in Patients Who Are Not Anemic and Who Will be Undergoing Orthopedic or Heart and Blood Vessel Surgery
The purpose of this study is to determine whether epoetin alfa will enable self-donation of at least 4 units of blood during the 2-week period before surgery (which is a shorter period of time than the conventional 3-week blood…
- Conditions
- Blood Transfusion, Blood Transfusion, Autologous, Orthopedic Procedures, Orthopedic Surgery
- Trial name
- NCT00270075
- Testing
- epoetin alfa
- Volunteers
- 80 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Osteotomy and Spinal Column Surgery
Study of the Effects of Hypnosis Before Undergoing Surgery, on Anxiety in Children Aged 10 to 18 Years
This study aims to find how hypnosis performed just before a painful surgery can change anxiety level, in children aged 10 to 18 years.
- Trial name
- HYPOPANX (NCT01320956)
- Testing
- Pre operative nurse consultation and Hypnosis, Pre operative nurse consultation
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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