Clinical trials: Preoperative
Sleep Disorder
Association Between Preoperative Insomnia and Postoperative Quality of Recovery : A Prospective Observational Study
Although patients with cancers are prone to insomnia, especially waiting for surgery during hospitalization, and insomnia promotes acute respiratory infections (ARI) and is not conducive to the postoperative quality of recovery…
- Trial name
- PIPQoR (NCT06008873)
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Preoperative Care, Patient Education
Integrating ChatGPT in Anesthesia
Patients are waiting for surgery longer than ever before. While hospitals are trying to get patients access to surgery as quickly as possible, a shortage of anesthesia doctors (called anesthesiologists) prevents this.
- Conditions
- Preoperative Care, Patient Education, Anesthesia, Artificial Intelligence
- Trial name
- NCT06652854
- Where
- Canada
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Breast Cancer
Therapy With Bevacizumab (BEV), Doxorubicin, and Cyclophosphamide Followed by BEV, Docetaxel, and Capecitabine Before Surgery Followed by BEV Alone After Surgery for Women With Locally Advanced Breast Cancer
Bevacizumab is an angiogenesis inhibitor which means it works to stop blood vessel formation in tumors. Without new blood vessels, the growth of a tumor is slowed. Chemotherapy drugs kill cancer cells more directly.
- Trial name
- NCT00365417
- Testing
- Bevacizumab, Doxorubicin, Cyclophosphamide
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- NSABP Foundation Inc
Postpartum Endometritis, Wound Infection
Chlorhexidine Vaginal Preparation for Reduction of Post-cesarean Endometritis and Sepsis
The study aims to assess the beneficial value of vaginal preparation with chlorhexidine gluconate 0.05% before cesarean delivery of cases in labor in reduction of postoperative endometritis, fever and wound complications compared…
- Conditions
- Postpartum Endometritis, Wound Infection, Chlorhexidine Adverse Reaction, Postoperative Fever
- Trial name
- NCT04385680
- Testing
- Chlorhexidine Gluconate vaginal solution 0.05%
- Where
- Saudi Arabia
- Volunteers
- 840 people
- Sponsor
- Zagazig University
Retinal Detachment, Diabetic Retinopathy
Avastin for PDR (Proliferative Diabetic Retinopathy)
The purpose of this study is to determine the effect of anti-VEGF drug (Avastin) adminstration in eyes prior to surgical treatment for Traction retinal detachment (TRD) in patients with Proliferative Diabetic Retinopathy (PDR).
- Trial name
- PDR (NCT01270542)
- Testing
- Avastin (bevacizumab)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Southern California
Breast Neoplasms, Breast Cancer
Surgical Outcome of BCS Using ICG-F in Breast Cancer Patients After Preoperative Chemotherapy
Neoadjuvant chemotherapy for advanced breast cancer has led to an increased rate of breast-conserving surgery (BCS) in these patients.
- Trial name
- NCT06780735
- Testing
- The margin-positive rate using the localization technique
- Where
- South Korea
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- National Cancer Center, Korea
Colorectal Cancer
Effect of Preoperative Chemoradiotherapy on Exercise Capacity as Measured by Cardiopulmonary Exercise Testing
This study will investigate the effect of preoperative chemoradiotherapy on exercise capacity as measured by cardiopulmonary exercise testing in patients with colorectal cancer.
- Trial name
- NCT00833508
- Testing
- Cardiopulmonary exercise testing
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Voluntary Termination of Pregnancy
Preoperative Ultrasound Evaluation of Gastric Contents in Voluntary Termination of Pregnancy During the First Trimester
This is an observational, prospective, monocentric, diagnostic study aiming to evaluate the diagnostic properties of the presence of nausea-vomiting in predicting the existence of gastric contents in preoperative surgical…
- Trial name
- ECHONAV (NCT06210308)
- Testing
- Data collection from gastric ultrasound
- Where
- France
- Volunteers
- 304 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Obesity, Bariatric Surgery Candidate
Difficult Airway in the Bariatric Patient: The BARINTUBE Cohort Study
Background: Difficult airway in bariatric patients presents significant challenges during anesthesia, impacting patient safety and surgical outcomes.
- Trial name
- BARINTUBE (NCT06592313)
- Testing
- Intubation
- Where
- Mexico
- Volunteers
- 1,290 people
- Sponsor
- : Manuel Alberto Guerrero Gutierrez
Colorectal Surgery
Efficacy Comparison of Two Preoperative Skin Antisepsis Preparations in Colorectal Surgery
Surgical site infections (SSI) are one of the most common complications in the post-operative patient, and the second most common health care associated infection overall.
- Trial name
- NCT01233050
- Testing
- 2% Chlorhexidine Gluconate/70% Isopropyl Alcohol, Iodine Povacrylex/74% Isopropyl Alcohol
- Where
- 3 sites in United States
- Volunteers
- 802 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Endometriosis
Comparison of Ultrasound-determined and Intraoperative #Enzian-classification in Patients With Deep Endometriosis
The Enzian classification, which was developed in order to describe deep endometriotic (DE) lesions, is determined intraoperatively by the surgeon.
- Trial name
- NCT04399668
- Where
- Austria
- Volunteers
- 745 people
- Sponsor
- Univ.-Doz. Dr.med.univ. Gernot Hudelist, MSc.
Surgery, Pain
A Dose Ranging Effect of Preoperative Diphenhydramine on Postoperative Quality of Recovery After Ambulatory Surgery
Pain after ambulatory surgery remains an unsolved problem in The United States and Europe. It is associated with delayed hospital discharge and it can result to an increased opioid consumption with adverse side effects.
- Trial name
- NCT01451762
- Testing
- .9 normal saline, 25 mg diphenhydramine IV, 50 mg diphenhydramine IV
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Northwestern University
Perioperative Medicine, Hip Fractures
Preoperative Echocardiography in Patients With Hip Fracture
Aim of the study was to assess whether preoperative echocardiography affects time to surgery, length of hospital stay and in hospital mortality in patients undergoing hip fracture surgery.
- Conditions
- Perioperative Medicine, Hip Fractures, Echocardiography
- Trial name
- NCT05869396
- Testing
- echocardiography
- Where
- Italy
- Volunteers
- 255 people
- Sponsor
- University of Florence
Obesity, Difficult Intubation
Preoperative Evaluation of Airway
Evaluation of airway markers of patients who have undergone obesity surgery.
- Trial name
- NCT03597880
- Testing
- obese patients
- Volunteers
- 489 people
- Sponsor
- Yeditepe University Hospital
Femur Fracture
Effect of Preoperative Carbohydrate Loading in Femur Fracture
Femur fracture is very common in older people. It makes the people bedridden for long time at hospital. The fracture of femur is generally managed by the surgical procedure.
- Trial name
- NCT04838366
- Testing
- Carbohydrate loading
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Armed Police Force Hospital, Nepal
Anaemia
Preoperative Intravenous Iron to Treat Anaemia in Major Surgery
Anaemia is a common problem in patients undergoing surgery. About half of patients undergoing a major operation have anaemia, often a consequence of the disease requiring surgery. Anaemia causes patients to feel tired and unwell.
- Trial name
- PREVENTT (NCT01692418)
- Testing
- Ferric carboxymaltose, Normal saline
- Where
- 28 sites in United Kingdom
- Volunteers
- 487 people
- Sponsor
- University College, London
Postoperative Pain
the Effect of Preoperative Pain Education by Anesthesia Nurses on Postoperative Pain Among Adult Patients Undergoing Abdominal Surgery
To explore the effects of preoperative pain education on postoperative pain among patients undergoing abdominal surgery.
- Trial name
- NCT06327282
- Testing
- education on pain and related knowledge
- Volunteers
- 116 people
- Sponsor
- Chinese PLA General Hospital
Colorectal Cancer
Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer
RATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as fluorouracil and leucovorin, work in different ways to stop the growth of tumor cells, either by killing the cells or…
- Trial name
- NCT00296608
- Testing
- fluorouracil, leucovorin calcium, conventional surgery
- Volunteers
- 762 people
- Sponsor
- Federation Francophone de Cancerologie Digestive
Acute Mesenteric Ischemia
Acute Intestinal Necrosis- the Preoperative Diagnostic Approach
To investigate a number of blood based parameters in patients with intestinal ischaemia compared to patients with other acute abdominal diseases.
- Trial name
- AIN (NCT05665946)
- Testing
- Blood sample analysis
- Volunteers
- 2,958 people
- Sponsor
- Aalborg University Hospital
Adenotonsillectomy
Intranasal Dexmedetomidine, Ketamine or Midazolam for Anxiety and Respiratory Complications in Children
This study is being done to find out which of three medications-dexmedetomidine, ketamine, or midazolam-is best at reducing anxiety and breathing problems in children having surgery to remove their tonsils and adenoids.
- Trial name
- INPERM (NCT07072117)
- Testing
- Intranasal Dexmedetomidine as a Premedication for Prevention of Anxiety & Respiratory Complications, Intranasal Ketamine as a Premedication for Prevention of Anxiety and Respiratory Complications, Intranasal Midazolam as a Premedication for Prevention of Anxiety and Respiratory Complications
- Where
- Egypt
- Volunteers
- 148 people
- Sponsor
- Zagazig University
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