Clinical trials: Preoperative
Colorectal Cancer
Bispecific Antibody in Finding Tumor Cells in Patients With Colorectal Cancer
RATIONALE: Diagnostic procedures, such as radionuclide imaging using bispecific antibody, may help find colorectal cancer cells and learn the extent of disease.
- Trial name
- NCT00895323
- Testing
- enzyme-linked immunosorbent assay, pharmacological study, whole-body scintigraphy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Garden State Cancer Center at the Center for Molecular Medicine and Immunology
Informed Consent, Awareness
Patients' Readings of Pre-operative Informed Consent Forms
Patient informed consent is a form which contains the patient's probable outcome of the procedure to be performed, and the probable risk and benefit of the patient's knowledge of the illness.
- Trial name
- NCT03555760
- Testing
- Observation of informed consent form readings of all patients who are scheduled for surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Ankara University
Fear, Pain Management
Influence of Preoperative Fear on Pain and Postoperative Outcomes
Fear of anesthesia plays a crucial role in the perioperative setting and can negatively affect recovery. The main objective is to assess the relationship between fear of anesthesia, surgeries, and hospitals and poorer…
- Conditions
- Fear, Pain Management, Anxiety, Complications of Surgical Procedures or Medical Care
- Trial name
- POSPoFe (NCT06785389)
- Testing
- Fear of anesthesia, surgery and hospitals scale, State-Trait Anxiety Inventory, Nummerical Rating Scale for postoperative pain
- Where
- Spain
- Volunteers
- 138 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Cancer, Heart Failure
Evaluation of Preoperative Acceptance of Proactive Palliative Care Intervention
Advances in medicine have led to an increased life expectancy even with complex disease courses of malignant diseases. This leads to frequent critical situations for patients and high risk surgical interventions.
- Conditions
- Cancer, Heart Failure, Chronic Obstructive Pulmonary Disease, Postoperative Complications
- Trial name
- iCare (NCT05575791)
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Arthoplasty, Nutrition
Effects of Preoperative Whey Protein and Exercise Support on Recovery After Total Hip Arthroplasty
Objective: The aim of this project is to evaluate the effects of preoperative whey protein supplementation and a physical exercise program on postoperative recovery outcomes in patients undergoing total hip arthroplasty (THA).
- Conditions
- Arthoplasty, Nutrition, Geriatric Assessment, Exercise Training
- Trial name
- THA (NCT07329010)
- Testing
- Preoperative Whey Protein and Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- TC Erciyes University
Rectal Cancer
Phase II Trial of Preoperative High-dose-rate Endorectal Brachytherapy and FOLFOX Chemotherapy for Rectal Cancer
Standard treatment for rectum cancer is a pre-surgery course of external beam radiotherapy given with chemotherapy at the same time.
- Trial name
- HDRBT (NCT01659424)
- Testing
- High Dose Rate Endorectal Brachytherapy (HDR-ERBT)
- Where
- 2 sites in United States
- Sponsor
- Beth Israel Medical Center
Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy
Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment
Vitreoretinal surgery for epiretinal proliferation tractional retinal detachment associated with proliferative diabetic retinopathy (PDR) is often complicated by hemorrhage from fibrovascular tissue.
- Conditions
- Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy, Tractional Retinal Detachment, Diabetic Retinopathy
- Trial name
- NCT00548197
- Testing
- Bevacizumab
- Where
- Iran
- Volunteers
- 40 people
- Sponsor
- Iran University of Medical Sciences
Uterine Fibroid
The Efficacy and Safety of Preoperative Misoprostol in Blood-loss Reduction During Myomectomy.
Open myomectomy remains the principal treatment for symptomatic fibroids in sub-Saharan countries irrespective of fertility desires.
- Trial name
- MM (NCT03509168)
- Testing
- Misoprostol Pfizer Brand, Non-insertion of Misoprostol Pfizer Brand
- Where
- Uganda
- Volunteers
- 46 people
- Sponsor
- Makerere University
Knee Osteoarthritis
In-home Versus Hospital Preoperative Training for Patients Undergoing Total Knee Replacement
In this work the importance of the potentiation and recovery of the balance with a physiotherapeutic intervention that begins in the early preoperative phase is compared with the conventional postoperative rehabilitation.
- Trial name
- home_ATR (NCT03100890)
- Testing
- Preoperative training (hospital), Preoperative training (home)
- Where
- Spain
- Volunteers
- 67 people
- Sponsor
- University of Valencia
Non-melanoma Skin Cancer, Squamous Cell Carcinoma of Skin
Same-day Versus Separate-day Preoperative Consultation for Mohs Surgery
The purpose of this study is to determine whether separate- versus same-day preoperative consultation affects time to treatment (start to finish), utilization rate of Mohs, rate of case cancellations, cost, and patient…
- Conditions
- Non-melanoma Skin Cancer, Squamous Cell Carcinoma of Skin, Basal Cell Carcinoma
- Trial name
- NCT02321982
- Testing
- Same-day preoperative consultation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Gastric Cancer, HER2-positive Gastric Cancer
Adjuvant TRastuzumab Deruxtecan for HER2-positive Gastroesophageal Cancer With Persistence of miNImal Residual Disease
TRINITY is designed as a multicentre, randomized, open-label, interventional phase II study aimed at investigating the activity, efficacy and safety of trastuzumab-deruxtecan (T-DXd) plus capecitabine/5-fluorouracil as a…
- Trial name
- TRINITY (NCT06253650)
- Testing
- Experimental, Control
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- Gruppo Oncologico del Nord-Ovest
Preoperative Anxiety
Feasibility Study Evaluating the Silva Module During the Anaesthesiology Consultation Before an Elective Surgery
In this feasibility study, feasibility, acceptability and an initial clinical efficacy of the new module of Hypnosis and Virtual Reality (or Digital Sedation), Silva, will be evaluated.
- Trial name
- Silva (NCT04379882)
- Testing
- Digital Sedation (Silva)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oncomfort
Kidney Calculi, Urinary Tract Infections
Is it Necessary for Patients With a Positive Urine Culture to Achieve a Negative Result After Antimicrobial Treatment Before Undergoing Percutaneous Nephrolithotomy?
Objective: The current European Association of Urology (EAU) guidelines do not provide clear recommendations on whether patients with a positive urine culture(UC) should wait until the culture turns negative following…
- Conditions
- Kidney Calculi, Urinary Tract Infections, Sepsis
- Trial name
- NCT06210425
- Where
- China
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Junhao Zheng
Lung Neoplasm
Home-based Preoperative Exercise Training for Lung Cancer Patients Undergoing Surgery
Lung cancer accounts for over 11% of global cancer incidence and is the leading cause of cancer death, with numbers in 2020 reaching 1.8 million deaths worldwide.
- Trial name
- NCT05469425
- Testing
- Preoperative home-based exercise training
- Where
- Portugal
- Volunteers
- 46 people
- Sponsor
- Instituto Politécnico de Leiria
Preoperative Anxiety
Effect of a Preparation Video on Preoperative Anxiety in Children Undergoing Dental Treatment Under GA
The present study investigated the effect of an animated preoperative preparation video in mitigating preoperative anxiety among children receiving comprehensive dental treatment under General Anesthesia (GA).
- Trial name
- NCT06612398
- Testing
- Preoperative preparation video
- Where
- Jordan
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Kidney Stone, Retrograde Intrarenal Surgery (RIRS)
MIRABEGRON AND UAS OUTCOMES DURING RIRS
The aim of this study is to evaluate whether there is a difference in the passage rate of the ureteral access sheath between patients who used mirabegron (a beta-3 receptor agonist) for overactive bladder and those who underwent…
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery (RIRS), Ureteral Access Sheath
- Trial name
- NCT07566416
- Testing
- Retrograde intrarenal surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 131 people
- Sponsor
- Ankara Training and Research Hospital
Surgical Site Infection, Unplanned Fracture-Related Reoperation
Pre-operative Aqueous Antiseptic Skin Solutions in Open Fractures
The prevention of infection is the single most important goal influencing peri-operative care of patients with open fractures. Standard practice in the management of open fractures includes sterile technique and pre-operative…
- Conditions
- Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture
- Trial name
- Aqueous-PREP (NCT03385304)
- Testing
- 10% povidone-iodine (1% free iodine) in purified water, 4% chlorhexidine gluconate (CHG) in purified water
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 1,638 people
- Sponsor
- University of Maryland, Baltimore
Gastric Ultrasound
Establishing Gastric Sonography in a Swiss Teaching Hospital
Preoperative gastric sonography may provide a validated, reliable, fast, and cost-efficient approach to assess aspiration risks in both elective and emergency patients.
- Trial name
- NCT04738006
- Where
- Switzerland
- Volunteers
- 2,003 people
- Sponsor
- Kantonsspital Winterthur KSW
Liver Transplantation
S100β and Neuron Specific Enolase Levels in Liver Transplantation
Several neurological problems which include both central nervous system and peripheral nervous system can occur as a result of acute liver failure or severe chronic liver failure.
- Trial name
- NCT03453047
- Testing
- S100β and Neuron specific enolase (NSE)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bora Dinc
Insulin Sensitivity
Preoperative Oral Carbohydrate Drink for Elective Cesarean Delivery and the Effect on Insulin Sensitivity
Preoperative fasting and surgery can cause metabolic stress and insulin resistance. Oral carbohydrate loading has been shown to attenuate the development of insulin resistance in the non-pregnant population undergoing many…
- Trial name
- NCT03494868
- Testing
- Carbohydrate Drink
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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