Clinical trials: Presbyacusis
Presbycusis
Computer-Based Auditory Rehabilitation
Hearing in noisy environments is a perceptual problem that is ubiquitous in modern industrialized societies. This particular listening context offers a particular challenge to individuals living with hearing impairment (30…
- Trial name
- NCT02147847
- Testing
- Video game based training 1, Video game based training 2
- Where
- 3 sites in United States
- Volunteers
- 36 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Presbycusis, Aging
At-home Auditory Training Clinical Trial
The purpose of this study is to investigate the effectiveness of an auditory training program used at home with the subject's own hearing aids.
- Conditions
- Presbycusis, Aging, Hearing Loss
- Trial name
- Training (NCT01950013)
- Testing
- Auditory training program
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Indiana University
Hearing Loss, Bilateral Sensorineural, Progressive, Hearing Loss, Bilateral (Causes Other Than Tumors)
Hearing Screening in Adults Over 50 Years Old
The goal of this single-arm quasi-experimental study is to evaluate the feasibility, effectiveness, and management of three different hearing screening methods in adults aged 50 years and older in the Czech Republic.
- Conditions
- Hearing Loss, Bilateral Sensorineural, Progressive, Hearing Loss, Bilateral (Causes Other Than Tumors), Hearing Loss, Bilateral or Unilateral, Presbyacusis
- Trial name
- HSA50+ (NCT06894927)
- Testing
- Screening HHIA questionnaire, Whispered voice test, Screening pure tone audiometry
- Where
- 2 sites in Czechia
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University Hospital Hradec Kralove
Age-Related Hearing Loss
Efficacy and Safety of AUT00063 Versus Placebo in Age-Related Hearing Loss
This study aims to demonstrate that the investigational drug AUT00063 is effective and safe in the treatment of age-related hearing loss.
- Trial name
- CLARITY-1 (NCT02345031)
- Testing
- AUT00063
- Where
- 13 sites in United States
- Volunteers
- 78 people
- Sponsor
- Autifony Therapeutics Limited
Hearing Loss, Age-Related
Hearing Aids Use in Elderly: Efficacy in Speech Perception and in Health-related Quality of Life
Background: Prevalence of hearing loss increases over age; its estimated prevalence is 40-50% in people older than 75 years. Recent studies agree that modification in the hearing threshold contributes to deterioration in…
- Trial name
- NCT04333043
- Testing
- audiological test, cognitive questionnaires
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Sensorineural Hearing Loss, Bilateral
Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis
The purpose of this study is to characterize and assess the evolution of hearing impairment of patients with adulthood-onset bilateral sensorineural hearing loss carrying mutations on GJB2 gene.
- Trial name
- SONG (NCT06354010)
- Testing
- Genotyping, Audiological assessments
- Where
- 2 sites in United States, France
- Volunteers
- 134 people
- Sponsor
- Sensorion
Presbycusis, Aging
Evaluating Hearing Aid Service Delivery Models
The purpose of this study is to compare the outcomes for two different hearing-aid delivery models. In one model, the audiologist selects and fits the hearing aid and, in the other model, the consumer does this directly.
- Conditions
- Presbycusis, Aging, Hearing Loss
- Trial name
- NCT01788423
- Testing
- hearing aid
- Where
- United States
- Volunteers
- 323 people
- Sponsor
- Indiana University
Hearing Loss, Age-Related, Presbycusis
Optimizing Elderly Hearing Loss Care in Hong Kong A Cost-Effectiveness and Satisfactory Analysis of a Pilot Collaborative Model Between Otorhinolaryngologists and Family Medicine Specialists
This study will evaluate a new collaborative elderly hearing-loss service in Hong Kong. The service is based in Family Medicine (FM) and supported by Ear, Nose and Throat (ENT) specialist nurses and audiology services.
- Trial name
- NCT07782177
- Where
- Hong Kong
- Volunteers
- 500 people
- Sponsor
- Tseung Kwan O Hospital, Hong Kong
Age-related Hearing Loss
Increasing Physical Activity with a Social Robot-assisted Exercise Intervention in Older Adults with Hearing Loss: a Feasibility and Pilot Randomized Controlled Trial
Objectives To assess the feasibility and acceptability of using a home-based, social robot-assisted intervention (SRAI) for older adults with hearing loss (HL), and to examine the preliminary effects of SRAI on improving physical…
- Trial name
- NCT06878339
- Testing
- A social robot KaKa-assisted intervention
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Presbyacusis
Use of Hearing Aids. Development and Implementation of a Counselling Program for Hearing Aid Users
The proportion of elderly people is expected to increase greatly within the next couple of decades, resulting in a proportional increase in the need for hearing rehabilitation.
- Trial name
- NCT02233361
- Testing
- Counseling
- Where
- Norway
- Volunteers
- 280 people
- Sponsor
- Lovisenberg Diakonale Hospital
Hearing Loss, Age-Related
Hearing-physical Activity Intervention
Background By 2050, approximately 2.5 billion people are expected to experience some degree of age-related hearing loss (ARHL). Greater ARHL is associated with decreased communication, reduced physical activity and social…
- Trial name
- NCT07071168
- Testing
- hearing-physical activity training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Presbycusis, Frailty Syndrome
Study of the Association Between Presbycusis With the Incidence of Frailty
The objective of the project is to establish the association between presbycusis and the incidence of frailty in humans in order to establish hearing loss with age as another index for the diagnosis of frailty; As well as…
- Conditions
- Presbycusis, Frailty Syndrome, Oxidative Stress
- Trial name
- NCT04360109
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Tinnitus
Caroverin and Inner Ear Diseases
This trial is a randomized, double blind, placebo controlled study on patients suffering from inner ear diseases with tinnitus as a principal symptom.
- Trial name
- NCT01174979
- Testing
- Caroverin
- Where
- Austria
- Volunteers
- 170 people
- Sponsor
- Phafag AG
Hearing Loss
Early Age-Related Hearing Loss Investigation Pilot Study
The purpose of this clinical trial pilot is to obtain feasibility and pilot data necessary to inform the hearing intervention being designed for a larger R01 clinical trial that seeks to determine whether best practice hearing…
- Trial name
- P-EARLHI (NCT05970211)
- Testing
- Phonak Audeo Lumity Receiver in Canal Hearing Aid
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hearing Loss, Hearing Impairment
HEARS Maryland: Extending Capacity for Affordable, Accessible Hearing Care Through Older Adult Peer Mentorship
This study aims to assess the effectiveness of a Community Health Worker (CHW) delivered hearing loss intervention program (HEARS) for older adults in Maryland in collaboration with community organizations.
- Conditions
- Hearing Loss, Hearing Impairment, Age Related Hearing Loss, Age-related Hearing Impairment
- Trial name
- HEARS MD (NCT07699146)
- Testing
- HEARS MD Device, HEARS MD Program
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hearing Loss, Depression
Treating Hearing Loss to Improve Mood and Cognition in Older Adults
Age-related hearing loss (ARHL) is the third most common health condition affecting older adults after heart disease and arthritis and is the fifth leading cause of years lived with disability worldwide.
- Trial name
- NCT03321006
- Testing
- Phonak Audeo B-R 90 hearing aid device (Active), Duloxetine or escitalopram
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- New York State Psychiatric Institute
Hearing Loss, Sensorineural, Presbycusis
Barriers and Facilitators to OTC Hearing Aids Success
Hearing aids can improve hearing, communication, and overall quality of life for people with hearing loss. However, not many people use hearing aids. A common reason is that hearing aids are expensive and hard to get.
- Trial name
- NCT06499805
- Testing
- Audiologist-based fitting, Over-the-counter fitting
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Yu-Hsiang Wu
Age-Related Hearing Loss, Postural; Defect
Postural Modification and Hearing Aids in Presbycusis
Presbycusis could be associated to increased risk to fall. There is little about the impact on postural balance of hearing aids.
- Conditions
- Age-Related Hearing Loss, Postural; Defect, Hearing Aid
- Trial name
- Post-AP (NCT05706051)
- Testing
- posturography
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Angers
Age-related Hearing Loss
First Clinical Study to Evaluate Safety, Tolerability & PK of DX243 in Healthy Volunteers and Patients With Hearing Loss
Phase 2a: Multiple Ascending Dose (MAD) in male and female patients with hearing loss: The study will be conducted according to a randomised, placebo-controlled, double-blind design.
- Trial name
- DX243-101 (NCT07637981)
- Testing
- DX243
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Dendrogenix
Hearing Loss, Age-Related
Hearing for Communication and Resident Engagement
Amplification is a well-established, evidence-based front-line treatment for those with impaired communication secondary to Age Related Hearing Loss (ARHL).
- Trial name
- HearCARE (NCT04575051)
- Testing
- Consult Model, Engage Model
- Where
- United States
- Volunteers
- 684 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh