Clinical trials: Presbyopia,
Presbyopia
OPTI-FREE® PureMoist® for Presbyopic Contact Lens Wearers
The purpose of this study is to evaluate OPTI-FREE® PureMoist® (OFPM) compared to non-HYDRAGLYDE® multi-purpose contact lens solutions in presbyopes currently wearing soft contact lenses and experiencing symptoms of dryness.
- Trial name
- NCT02965820
- Testing
- Opti-Free® PureMoist® contact lens solution, Habitual Multi-Purpose Contact Lens Solution, Habitual Contact Lenses
- Volunteers
- 122 people
- Sponsor
- Alcon, a Novartis Company
Aphakia, Presbyopia
Clareon PanOptix Pro vs. Clareon PanOptix - Study A
The purpose of this study is to evaluate the safety and effectiveness of Clareon™ PanOptix™ Pro Trifocal Intraocular Lens (IOL) compared to Clareon™ PanOptix™ Trifocal IOL.
- Trial name
- NCT06400745
- Testing
- CPO Pro IOL, CPO IOL, Cataract surgery
- Where
- 8 sites in United States
- Volunteers
- 87 people
- Sponsor
- Alcon Research
Myopia, Ametropia
Clinical Evaluation of the Safety and Efficacy of a New Multifocal Contact Lens
The purpose of this study was to demonstrate substantial equivalence of the new DAILIES® AquaComfort Plus® Multifocal (DACP MF) contact lens to the commercially available Focus® DAILIES® Progressives (FDP) contact lens.
- Conditions
- Myopia, Ametropia, Presbyopia, Refractive Error
- Trial name
- NCT01797783
- Testing
- Nelfilcon A multifocal contact lens with comfort additive, Nelfilcon A multifocal contact lens
- Volunteers
- 83 people
- Sponsor
- Alcon Research
Presbyopia
Multifocal Contact Lens Use in Previous Contact Lens Wearers With Near Vision Demands
The purpose of this study is to evaluate the use of a multifocal contact lens in people who previously wore contact lenses but discontinued due to age-related, near vision demands.
- Trial name
- GARM (NCT00965237)
- Testing
- lotrafilcon B multifocal contact lens, lotrafilcon B single vision contact lens, Over-reader spectacles
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- CIBA VISION
Presbyopia
A Dispensing Clinical Trial of Comfilcon A Extended Range Multifocal Lenses
The aim of this study is to validate the clinical of comfilcon A extended range high add center near (CN) multifocal lenses in existing contact lens wearers against the current comfilcon A high add multifocal lenses.
- Trial name
- NCT02719353
- Testing
- comfilcon A Extended Range test lens, comfilcon A control lens
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens
This study is a randomized, single-masked, crossover clinical trial. There are two study lenses. Each lens will be dispensed for 3 ± 1 days and then an optimization visit will occur.
- Trial name
- NCT04189224
- Testing
- JJV Investigational Multifocal Contact Lens, 1-Day Acuvue® Moist Brand Multifocal Contact Lens
- Where
- 4 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
A Study to Evaluate the Product Performance of a Low Add MultiFocal Soft Contact Lens
The objective of this study is to evaluate the product performance of an investigational multifocal low add soft contact lens.
- Trial name
- NCT01539694
- Testing
- LD118033 contact lens, PureVision multifocal contact lens
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Errors, Presbyopia
Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
The purpose of this clinical trial is to assess on-eye performance and overall fit of an investigational multifocal toric contact lens to aid in confirmation of the study lens design.
- Conditions
- Refractive Errors, Presbyopia, Astigmatism
- Trial name
- NCT05886907
- Testing
- Lehfilcon A multifocal toric contact lenses, Samfilcon A multifocal toric contact lenses, CLEAR CARE
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Presbyopia
Safety and Efficacy Study BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic or Pseudophakic Presbyopia
Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
- Trial name
- NCT05270863
- Testing
- BRIMOCHOL™ PF, Carbachol PF, Brimonidine tartrate
- Where
- 15 sites in United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Visus Therapeutics
Astigmatism, Presbyopia
A Clinical Comparison of Two Multifocal Toric Soft Contact Lenses
This study aims to compare the short-term clinical performance of the two study contact lenses.
- Trial name
- NCT06438601
- Testing
- Lens A (omafilcon A), Lens B (comfilcon A)
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- CooperVision, Inc.
Presbyopia Condition
A Randomized, Active-Controlled, Double-Masked, Crossover Study to Evaluate the Clinical Performance of Deseyne (Vifilcon C) Daily Disposable Soft Contact Lens for Presbyopia Extended Depth of Focus (EDOF)
The goal of this clinical trial is to learn if the contact lens we are testing will work to extend the range of clear focus at distance to provide an increase in clear vision at closer ranges without the additional need for…
- Trial name
- EDOF (NCT06698731)
- Testing
- Test lens, Control lens
- Where
- 3 sites in United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Bruno Vision Care
Presbyopia
Evaluating Two Multifocal Daily Disposable Contact Lenses
The objective of the study was to adapt existing multifocal soft lens wearers to a Control Lens for at least 2 weeks and then evaluate the success of switching them to the Test Lens, with a review after 2 weeks.
- Trial name
- NCT05579886
- Testing
- Control Lens, Test Lens
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Presbyopia
An Evaluation of the Safety of CSF-1 in Presbyopic Subjects
This is a multi-center, double-masked, vehicle-controlled study. The purpose of the study is to evaluate the safety of CSF-1 compared with vehicle in presbyopic subjects. Subjects will be treated for at least 6 weeks.
- Trial name
- NCT05393895
- Testing
- CSF-1, Vehicle
- Where
- 12 sites in United States
- Volunteers
- 178 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Presbyopia
Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses
The purpose of this study is to evaluate the on-eye multifocal clinical performance of investigational LID233309 contact lenses and Oasys multifocal (MF) contact lenses in a daily wear dispensing trial.
- Trial name
- NCT06469242
- Testing
- Serafilcon A multifocal contact lenses, Senofilcon A multifocal contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
- Where
- 8 sites in United States
- Volunteers
- 106 people
- Sponsor
- Alcon Research
Presbyopia
Handling Comparison Between Two Contact Lens Types
Subjects will evaluate each study lens in a random order. The lenses will be worn in both eyes for a short period.
- Trial name
- NCT02310126
- Testing
- etafilcon A (multi-focal), etafilcon A (sphere)
- Where
- 8 sites in United States
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Performance of a Multifocal Contact Lens - Presbyopia Study
This is a four week study to evaluate the performance of a multifocal contact lens in habitual wearers of silicone hydrogel multifocal contact lenses.
- Trial name
- NCT02450747
- Testing
- etafilcon A MULTIFOCAL
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Refractive Errors
Assessing Fitting Guides in Alcon Multifocal Contact Lenses
The purpose of this study is to compare an alternative fitting guide to a current fitting guide for optimizing contact lens parameters and determining contact lens prescription.
- Trial name
- NCT03118934
- Testing
- Lotrafilcon B multifocal contact lenses, Nelfilcon A multifocal contact lenses, Delefilcon A multifocal contact lenses
- Where
- 20 sites in United States, Canada and 1 more
- Volunteers
- 188 people
- Sponsor
- Alcon Research
Presbyopia
Clinical Evaluation of a Multifocal Contact Lens on Symptomatic Patients
The purpose of this study is to evaluate the effect of a multi-focal contact lens on symptomatic patients.
- Trial name
- NCT01016652
- Testing
- etafilcon A multifocal contact lens, etafilcon A Contact Lens
- Where
- 8 sites in United States
- Volunteers
- 49 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia, Astigmatism
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
The purpose of this study is to evaluate on-eye clinical performance of the investigational contact lenses following 30 days of wear in the intended population.
- Trial name
- NCT06461455
- Testing
- Lehfilcon A multifocal for astigmatism contact lenses, Samfilcon A multifocal for astigmatism contact lenses, CLEAR CARE® Cleaning & Disinfecting Solution
- Where
- 11 sites in United States
- Volunteers
- 95 people
- Sponsor
- Alcon Research