Clinical trials: Preschool
Dental Restoration Failure of Marginal Integrity
Outcomes of Restoring Untreated and SDF-treated Dentine Caries Lesions in Primary Teeth of Preschool Children
The primary objective of this proposed clinical study is to compare the success rates of ART restorations placed in untreated and SDF-treated dentine caries lesions in primary teeth.
- Trial name
- NCT03657862
- Testing
- application of 38% silver diamine fluoride solution
- Where
- China
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Anxiety
Feasibility and Preliminary Outcomes of the Brave Elephant Program: A Single-Arm Pretest-Posttest Study
Anxiety disorders are highly prevalent in childhood and have increased following the COVID-19 pandemic. Behavioral inhibition in early childhood is a well-established risk factor for later anxiety.
- Trial name
- Brave_Elephant (NCT07567820)
- Testing
- Brave Elephant Program
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ISPA - Instituto Universitario de Ciencias Psicologicas, Sociais e da Vida
Anemia, Undernutrition
Effect of Iron Versus Multiple Micronutrient Supplementation on Anemia in Preschool Children of Malaria-Endemic Area
Some micronutrients are likely to interact with malaria parasite, leading to either synergistic or antagonist effect on malaria morbidity and therefore on hemoglobin response.
- Trial name
- NCT00628459
- Testing
- micronutrient supplementation
- Where
- Burkina Faso
- Volunteers
- 297 people
- Sponsor
- Centre National de la Recherche Scientifique et Technologique
Mental Disorder, Child
Early Intervention Skills for Preschool Children With Emotional and Stress Related Disorders
This study is about early intervention for preschool children with emotional and stress related disorders. To develop a set of program that could be used in district hospitals for early intervention of preschool children with…
- Trial name
- NCT02991378
- Testing
- Children's emotional and stress coping program
- Where
- China
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Wheeze
Combined Glucocorticoid Adrenergic Therapy For Wheezy Preschool Children
The investigators goal is to conduct a pilot randomized controlled trial (RCT) whose purpose is to determine the feasibility of a randomized trial designed to determine if either inhaled beclomethasone or a combination of inhaled…
- Trial name
- CONjuGATE (NCT02319564)
- Testing
- Beclomethasone, Beclomethasone and Salbutamol, Aerochamber Max®
- Where
- Canada
- Sponsor
- University of Calgary
Asthma in Children, Dysbiosis
Respiratory Dysbiosis in Preschool Children with Asthma: Predictive of a Severe Form
The prevalence of asthma in preschool children is between 11 and12%. Inhaled corticosteroid therapy is the main therapy used, however this treatment seems insufficiently effective in some children.
- Trial name
- DREAM (NCT05192499)
- Testing
- Stool test, Blood test, Induced sputum
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Pain, Postoperative
Ultrasound Guided Caudal Block Versus Quadratus Lumborum Block in Children
To compare between caudal block and ultrasound guided Quadratus Lamborum block in reducing postoperative pain, opioid consumption, and recovery time following elective inguinal herniorraphy.
- Trial name
- NCT03811392
- Testing
- Hernioraphy/Caudal block, Hernioraphy/Quadratus Lumborum block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- University of Alexandria
Preoperative Anxiety, Emergence Delirium in Pediatric Anesthesia
Ride-On Toy Car Use During Operating Room Transfer in Preschool Children
The goal of this clinical trial is to determine whether the method of transfer to the operating room can reduce preoperative anxiety and postoperative emergence delirium in male children aged 3 to 7 years undergoing elective…
- Trial name
- NCT07403747
- Testing
- Toy car, Standard Transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Wheezing
Phenotypes of Preschool Wheezing Among Children Attending Sohag University Hospital
Wheezing in preschool children is very common, with a wide differential diagnosis. It is essential to be sure of the exact sound that parents are describing; the term 'wheeze' is often applied to non-specific sound.Approximately…
- Trial name
- NCT06603584
- Testing
- Chest x- Rays
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Physical Activity, Obesity, Childhood
The MOVI-HIIT Pilot Trial: The Impact of Activity Breaks on Cognitive Function, Adiposity and Fitness in Preschoolers
Pilot study to test the acceptability and feasibility of an intervention aimed to test the effectiveness, in preschool children, of an integrated physical activity intervention in the classroom based on intervallic training…
- Conditions
- Physical Activity, Obesity, Childhood, Cardiovascular Diseases, High Intensity Interval Training
- Trial name
- NCT05243784
- Testing
- MOVI-HIIT intervention
- Where
- Spain
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Motor Activity, Motor Coordination
Does Daily Physical Education Improve Motor Skill Development and Health-Related Physical Fitness in Preschool Children?
Background: During childhood, physical activity (PA) plays a fundamental role in motor development, as movement experiences during this critical period support the acquisition of both fine and gross motor skills (GMS) and foster…
- Conditions
- Motor Activity, Motor Coordination, Child Development, Excercise
- Trial name
- NCT07709949
- Testing
- Six-month daily PE program (5x/week), led by PE specialists and teachers, combining ball sports, gymnastics, athletics, yoga, aerobics, dance, and martial arts for preschoolers.
- Where
- Serbia
- Volunteers
- 323 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad
Parental Emotion Socialization, Parents' Beliefs About and Reactions to Children's Emotions
Tuning in to Kids® for Parents of Preschool-aged Children in Portugal
Early parent-child interactions, namely how parents respond to their children's emotions (i.e., emotion socialization parenting practices [ESPP]), may play a critical role in how children develop emotion regulation abilities.
- Conditions
- Parental Emotion Socialization, Parents' Beliefs About and Reactions to Children's Emotions, Parental Emotion Regulation
- Trial name
- TIK-PT (NCT07350083)
- Testing
- Tuning in to Kids®
- Where
- Portugal
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Lusofona University
Asthma
Inflammatory and Immune Profiles During a Severe Exacerbation in Preschool Asthmatic Children (<5 Years)
Asthma/wheeze begins in the first years of life and is the most common chronic disease in preschool children (< 5 years). Different phenotypes have been suggested: Episodic-Viral Wheeze (EVW), absence of symptoms between…
- Trial name
- VIRASTHMA2 (NCT03960359)
- Testing
- Clinical, microbiological and inflammatory phenotype
- Volunteers
- 150 people
- Sponsor
- University Hospital, Lille
Anxiety Mild to Moderate, Inhibition (Psychology)
Tiny Heroes Compared to Treatment as Usual to Decrease and Prevent Anxiety Problems in Young Children - a Randomized Controlled Study
The aim of this randomized controlled trial is to evaluate the effectiveness and cost-effectiveness of Tiny Heroes, a parent-directed internet-delivered cognitive behavioral therapy (iCBT) program for anxiety problems in children…
- Trial name
- NCT07870213
- Testing
- Parent-directed online cognitive behavioral therapy, Treatment as Usual (TAU)
- Volunteers
- 350 people
- Sponsor
- Karolinska Institutet
Child Development, Child Behavioral Problems
LOVING (Learning About Our Behavior is Valuable for Increasing Nurturing Relationships and Healthy Growth) RCT
The LOVING study is a randomized controlled trial designed to determine whether adaptations to an internationally recognized parenting program that enhances sensitive caregiving likewise improves sensitive caregiving in Singapore…
- Conditions
- Child Development, Child Behavioral Problems, Parent Child Relationship
- Trial name
- LOVING (NCT07687524)
- Testing
- VIPP-SD-SingH, "Video-Feedback Intervention to Promote Positive Parenting and Sensitive Discipline Adapted for the Singapore Context with a Health Component", CARE-SD, "Caregiver Awareness of Relationships through E-learning for Sensitivity and Discipline", NeuroEducation for Parents
- Where
- 5 sites in Singapore
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Up-to-date Immunization Status for Children in Child Care
Immunization Protection in Child Care (IPiCC) Project
Ensuring that all children are fully immunized against vaccine-preventable diseases is a critical public health issue. Child care programs are critical targets for efforts to increase the proportion of infants and young children…
- Trial name
- IPiCC (NCT01773759)
- Testing
- Intervention child care programs
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Utah
Preschool Children's Health Behaviors, Parental Support
Theory-Based Parenting Intervention for Preschool Children's Health Behaviors
The goal of this study is to test whether a 4-week online program can help parents better support health behaviors of their preschool children (aged 3-6 years).
- Trial name
- NCT07458009
- Testing
- A 4-week theory-based online intervention targeting parental support
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Mental Health Issue, Externalizing Behavior Problems
3D-Transition: Challenges and Resources of Children and Their Families During the Transition From Preschool to School
The 3D-Transition study is a follow-up of the 3D Cohort pregnancy study (NCT03113331, which covered from the 1st trimester of pregnancy to age 2 years) as the children transition into kindergarten and first grade.
- Conditions
- Mental Health Issue, Externalizing Behavior Problems, Internalizing Behavior Problems, Cognitive Development
- Trial name
- NCT04873518
- Where
- 3 sites in Canada
- Volunteers
- 939 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Autism
Psychophysiological Effects of Lactobacillus Plantarum PS128 in Preschool Children With Autism Spectrum Disorder
Autism Spectrum Disorders (ASD) comprises a complex group of disorders of neuronal development characterized by social and communication impairment along with presence of repetitive and restrictive behaviors.
- Trial name
- NCT03982290
- Testing
- Probiotic, Lactobacillus plantarum PS128
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Screen Time
Prospective Associations Between Screen Media Use and Physical Activity in Preschool Children
The aims of this study are as follows: The primary aim is to investigate the relationship between changes in screen media use with changes in non-sedentary time (time, min/day, spent in activities other than lying and sitting)…
- Trial name
- NCT04395287
- Testing
- Leisure screen time
- Where
- Denmark
- Volunteers
- 887 people
- Sponsor
- University of Southern Denmark