Clinical trials: Prescriptions
Opioid Overdose
Project OOPEN: Opioid Overdose Prevention, Education and Intervention
This prospective, randomized emergency department trial will study the effectiveness of an intervention that combines opioid overdose prevention, education and intervention that includes take home naloxone with brief behavioral…
- Trial name
- OOPEN (NCT01788306)
- Testing
- OOPEN+BBCC
- Where
- 3 sites in United States
- Volunteers
- 256 people
- Sponsor
- University of Washington
Head and Neck Cancer
Individualized Response-adaptive Radiation Dose Prescription in HNC Based on MRI
This Phase 1 dose-finding study investigates the maximal tolerated dose for a subsequent phase 2 trial testing MR-guided individualized response-adaptive dose prescription in HNC.
- Trial name
- MRL-02 (NCT05160714)
- Testing
- Real-time ADC-guided response adaptive Boost in HNC
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University Hospital Tuebingen
Substance-Related Disorders
Benzodiazepines in Opiate Replacement Therapy
Drug-related deaths (DRD) are a significant and increasing public health problem in Scotland. Benzodiazepines and BZD-type substances (BZD) are increasingly implicated in DRD.
- Trial name
- BENZORT (NCT04622995)
- Testing
- Benzodiazepine
- Where
- United Kingdom
- Volunteers
- 46,899 people, healthy volunteers welcome
- Sponsor
- University of Stirling
Diabetes Mellitus, Type 2
The Prescription Patterns and Clinical Efficacy of Tenero Tab/Tenero M SR Tab
This study is to observe the prescription patterns and clinical efficacy of patients prescribed with Tenero Tab/Tenero M SR Tab for diabetes treatment in routine clinical practice.
- Trial name
- NCT06188234
- Where
- South Korea
- Volunteers
- 3,000 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Diabetic Non-proliferative Retinopathy, Type2 Diabetes
Clinical Study of Tang Wang Prescription Intervene Diabetic Non-proliferative Retinopathy
This study include 384 Participants with diabetic non-proliferative retinopathy Design Method: Randomized, double blind, placebo controlled and multicenter clinical study.
- Trial name
- NCT03025399
- Testing
- Tangwang prescription
- Volunteers
- 384 people
- Sponsor
- Fengmei Lian
Fibromyalgia
Evaluation of Adherence of Women With Fibromyalgia to Walking Prescriptions
Although there are many studies evaluating adherence to supervised walking programs in patients with fibromyalgia (FM), there are limited studies evaluating adherence to unsupervised walking programs.
- Trial name
- NCT05996692
- Testing
- Evaluation of adherence to walking prescriptions
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Neurodermatitis
Study of Dupilumab for the Treatment of Patients With Prurigo Nodularis, Inadequately Controlled on Topical Prescription Therapies or When Those Therapies Are Not Advisable (PRIME2)
Primary Objective: To demonstrate the efficacy of dupilumab on itch response in participants with prurigo nodularis (PN), inadequately controlled on topical prescription therapy or when those therapies are not advisable.
- Trial name
- NCT04202679
- Testing
- Dupilumab SAR231893, Moisturizers, Low to medium potent topical corticosteroids
- Where
- 57 sites in United States, Canada and 9 more
- Volunteers
- 160 people
- Sponsor
- Sanofi
Fracture Femur, Fracture Tibia
Standard Versus Short Course Prophylactic Antibiotic in Femur and Tibia Shaft Fractures Managed With Intramedullary Interlocking Nail
Long-bone fractures, particularly of femur and tibia, are common following fall injury and road traffic accidents.1,2 The standard treatment is "intramedullary nailing," where a metal rod is inserted into the center of the bone…
- Conditions
- Fracture Femur, Fracture Tibia, Surgical Site Infection (SSI), Antibiotic
- Trial name
- NCT07554079
- Testing
- Short Course Antibiotics, Standard Course Antibiotics
- Where
- Nepal
- Volunteers
- 56 people
- Sponsor
- Kathmandu University School of Medical Sciences
Sedentary Lifestyle
Effectiveness of a Physical Exercise Prescription Program in Primary Care for Adults Aged 65 and Older: PREFIS-AP
This randomized controlled trial aims to evaluate the effectiveness of an individualized Physical Exercise Prescription Program delivered in Primary Care for adults aged 65 years and older.
- Trial name
- NCT07394790
- Testing
- Physical Exercise Prescription Program
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Biomédica de Salamanca
Opioid-Related Disorders, Drug Overdose
Prescribe to Save Lives
The U.S. is in the midst of an epidemic of opioid overdose deaths. The common use of opioids among persons living with HIV, along with their common use of benzodiazepines, has resulted in high rates of opioid overdose among this…
- Trial name
- PTSL (NCT03175640)
- Testing
- Implementation intervention
- Where
- 2 sites in United States
- Volunteers
- 294 people
- Sponsor
- Baystate Medical Center
Mild Cognitive Impairment (MCI)
Validation of Population Characteristics and Dosage Prescriptions for Cognitive Function Intervention Benefits of Different Doses of Tai Chi in Elderly Patients With Mild Cognitive Impairment: A Real-World Cross-Sectional Study
This is a companion real-world external validation study of two pre-registered parent randomized controlled trials (RCTs, protocol IDs: FujianUTCM-1 and FujianUTCM-2).
- Trial name
- NCT07608510
- Testing
- 24-form Simplified Tai Chi (Observational Behavioral Exposure)
- Volunteers
- 150 people
- Sponsor
- Lidian Chen
Pain, Postoperative, Opioid Misuse
Reduced Opioid Prescription After Laparoscopic Hysterectomy
Given the nationwide epidemic of opioid use and abuse (in part due to over prescription), this study aims at addressing the need for opioid prescription after laparoscopic hysterectomy.
- Conditions
- Pain, Postoperative, Opioid Misuse, Opioid Use, Pain
- Trial name
- NCT05548582
- Testing
- OxyCODONE 5 mg Oral Tablet, Acetaminophen 500 mg Tab, Ibuprofen 600 mg
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Obesity, Morbid, Drug Use
Evaluation of the Implementation of Drug Prescription Recommendations Using Clinical Decision Support in Patients With Severe Obesity: Retrospective Study
No drug prescription guidelines for severe obesity (BMI>35 kg/m2) are available, leading to non-standardized and / or potentially inappropriate drug management.
- Trial name
- RECOB-MED (NCT06517303)
- Where
- 2 sites in France
- Volunteers
- 1,050 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Healthy Older Adults
Yoga Empowers Seniors Study
This is an Intervention Development Study (IDS) to quantify the physical demands (using biomechanical investigation) of a 2-phase (beginning \& intermediate), 32-week yoga program designed for community-dwelling older adults.
- Trial name
- YESS (NCT01411059)
- Testing
- yoga
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Baseline Epidemiologic Assessment
Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)
The main objectives of this study are to provide surveillance/descriptive data to (a) assess utilization of MorphaBond ER and selected comparators overall and by age group and census regions using nationally-projected quarterly…
- Trial name
- BEAD-MB (NCT04033094)
- Testing
- MorphaBond ER, Comparator Drug
- Where
- United States
- Volunteers
- 17,566 people
- Sponsor
- Daiichi Sankyo
Patients, Programming Languages
Designing a Programming Language for Patient-Oriented Prescriptions
The purpose of this study is to create a human-readable and executable computer language to implement medical prescriptions and to evaluate and refine this language, with the goal of improving safety and efficacy of patient care.
- Trial name
- POP-PL (NCT02820168)
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Northwestern University
HIV Seropositivity, HIV Testing
Free HIV Testing in Private Biological Laboratories: A New Offer to Encourage HIV Testing
The program " Au labo sans ordo " aims to increase HIV testing coverage, in order to improve the first stage of the HIV care cascade in Paris and the Alpes-Maritimes, areas facing a much higher HIV epidemic than the other regions…
- Trial name
- ALSO (NCT04030689)
- Testing
- data collected from patient file
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Overdose, Adverse Event
Consequences of Doing What Should Not be Done in Primary Care
Retrospective observational study in a random selection of 5% of digital records active between 2014 and 2017 to quantify the frequency of Do not do primary care recommendations, calculating the over-cost related to them and…
- Trial name
- SOBRINA (NCT03482232)
- Testing
- Benzodiazepines, Non-steroidal anti-inflammatory drugs, paracetamol
- Where
- 2 sites in Spain
- Volunteers
- 750,000 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Benign Prostate Hyperplasia
Evaluation of the Potential Association Between 5α-reductase Inhibitors Prescription and Occurrence of High Grade Prostate Cancers
This is a multicenter, cohort study based on medico-administrative data from pathology laboratory registries and drug reimbursement files (CNAM-TS).
- Trial name
- CANARI (NCT02873117)
- Testing
- Prostate biopsy, prostatectomy or prostate resection
- Where
- France
- Volunteers
- 5,154 people
- Sponsor
- Rennes University Hospital
Opioid Overdose, Opiate Overdose
Nalmefene vs Naloxone for the Treatment of Recurrent Respiratory Depression After Opioid Overdose
The goal of this clinical trial is to compare naloxone to nalmefene for the treatment of opioid overdose in adults. The main questions it aims to answer are: Does nalmefene lower the number of doses of medicine participants need…
- Trial name
- NCT06408714
- Testing
- Nalmefene Injection, Naloxone Injection
- Where
- United States
- Sponsor
- University of New Mexico
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