Clinical trials: Prescriptions
Physical Activity, Sedentary Lifestyle
Activity Prescription in Clinical Practice
Most adults do not achieve the US aerobic physical activity (PA) guidelines (≥150 minutes/week of at least moderate intensity PA).
- Trial name
- NCT03695016
- Testing
- ActiveGOALs
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Pittsburgh
Chronic Heart Failure
Impact of Formulary Coverage of Entresto (Sacubitril/Valsartan) on Prescription Abandonment/Rejection and Subsequent Treatment and Economic Outcomes in Chronic Heart Failure Patients in the U.S.
This was a retrospective cohort study utilizing IQVIA open-source pharmacy and medical claims data among patients with a sacubitril/valsartan (SAC/VAL) prescription transaction.
- Trial name
- NCT05848206
- Where
- United States
- Volunteers
- 251,831 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Pain, Opioid Misuse
French Version of POMI Scale
French translation and validation of the Prescription Opioid Misuse Index scale (POMI), a brief questionnaire to assess opioid prescription misuse.
- Trial name
- POMI (NCT04979364)
- Volunteers
- 154 people
- Sponsor
- University Hospital, Clermont-Ferrand
Cancer-Related Fatigue, Colorectal Cancer
Cangpo Liujun Prescription on Cancer-related Fatigue in Advanced Colorectal Cancer With Spleen Deficiency and Dampness Excess
The goal of this clinical trial is to learn if Cangpo Liujun Prescription works to treat cancer-related fatigue in patients with advanced colorectal cancer undergoing second-line chemotherapy with spleen deficiency and dampness…
- Trial name
- NCT06394128
- Testing
- Cangpo Liujun Prescription
- Where
- China
- Volunteers
- 48 people
- Sponsor
- First People's Hospital of Hangzhou
Overdose, Risk Behavior
The Impact of a Web-Based Naloxone Intervention Under Standing Orders to Patients Prescribed Chronic Opioid Therapy
In the setting of naloxone standing orders, this study will assess the impact of a targeted, web-based overdose prevention and naloxone intervention for patients prescribed chronic opioid therapy.
- Trial name
- NCT03337009
- Testing
- Naloxone Navigator (NN)
- Where
- United States
- Volunteers
- 1,004 people
- Sponsor
- Kaiser Permanente
HIV-positive Individuals
MyTPill: A Novel Strategy to Monitor Antiretroviral Adherence Among HIV+ Prescription Opioid Users
This study compares several different antiretroviral adherence measures, including digital pills, in HIV+ individuals who are maintained on opioid analgesics.
- Trial name
- MyTPill (NCT03978793)
- Testing
- MyTPill, a digital pill
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Ohio State University
Chronic Disease
Feasibility Study of the Medication Review With Follow up Service for Patients With Polypharmacy in Swiss Community Pharmacies
In Switzerland, it is estimated that 20,000 people are hospitalized each year as a result of drug related problems (DRP). Community pharmacies (CP) are well positioned to identify and manage such DRPs in a timely manner.
- Trial name
- MaJ? (NCT05348538)
- Testing
- Medication review with follow up or MaJ? for the acronym in french
- Where
- Switzerland
- Volunteers
- 162 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Primary Health Care for Children
Impact of a Real-time Mentoring Tool on Antibiotic Prescription (medAL-mentor)
The goal of this ancillary study, part of the DYNAMIC project, is to reduce antibiotic prescription and improve the quality of care for children in primary care in Tanzania using a near real-time mentoring tool (called…
- Trial name
- medAL-mentor (NCT05901155)
- Testing
- MedAL-mentor
- Where
- 40 sites in Tanzania
- Volunteers
- 37,000 people
- Sponsor
- Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland
Coronary Artery Disease
Influence of Intensive Lipid-lowering on FFRCT (The FLOW-PROMOTE Study)
The FLOW-PROMOTE Study is an investigator-initiated, Danish multicenter study of patients with stable chest pain investigating whether lipid lowering is associated with recovery of impaired coronary flow as assessed by CT derived…
- Trial name
- FlowPromote (NCT04737408)
- Testing
- Rosuvastatin 40mg
- Where
- 3 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Bjarne Linde Noergaard
Diet, Healthy Growth
'Food, Fun, Fresh, Family' Program for Healthy Eating and Growth for Elementary-age Children.
The goal of this community-based randomized trial in elementary-aged children and a caregiver (parent/guardian) is to test the effect of providing families with produce and grocery store gift cards (family support) in conjunction…
- Trial name
- FUEL (NCT06010784)
- Testing
- Family support, BGCAA's after-school program with CATCH curriculum
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Texas at Austin
Gait, Hemiplegic
Understanding the Effects of Quantitatively-Prescribing Passive-Dynamic Ankle-Foot Orthosis Bending Stiffness for Individuals Post-Stroke
When people walk, their ankle joints help to hold them upright and move them forward. Ankle braces are often given to people who have had a stroke to help their ankle joints work properly.
- Trial name
- NCT04619043
- Testing
- Ankle Orthotic
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Delaware
Adult Growth Hormone Deficiency
Metabolic Endocrinology and Growth Hormone in Adults
This is a multicentric, longitudinal, observational study with the prospective follow-up of Adult subjects with Growth Hormone Deficiency (AGHD) being treated with Saizen, every six months in the first year and then annually.
- Trial name
- MEGHA FRANCE (NCT01080755)
- Volunteers
- 90 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Low Back Pain, Opiate Addiction
Study of Opioid Use After Lumbar and Cervical Spine Surgery
The purpose of this project is to assess the impact of an educational video on the use of prescription opioid medication during a 6-month period following spine surgery.
- Conditions
- Low Back Pain, Opiate Addiction, Neck Pain
- Trial name
- SOULCS (NCT02674711)
- Testing
- Educational Video
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Brooke Army Medical Center
Dental Arch Relationship Anomaly
Influence of Four Orthodontic Bracket Prescriptions in Arch Width and Torque
The study compares torque and arch width changes between four different orthodontic bracket prescriptions and determine whether changes in dental torque are correlated to changes in arch width at the end of orthodontic treatment.
- Trial name
- NCT04043013
- Testing
- Mini-Taurus® (Rocky Mountain©) Brackets, Smart Clip® SL3 High Torque (3M Unitek©), Tip-Edge Plus® (TP Orthodontics©)
- Volunteers
- 76 people
- Sponsor
- University of Valencia
Amputation, Prosthesis User
Optimizing Prosthetic Prescription to Mitigate the Effects of Perspiration
The specific aim of this research is to compare three clinically available liners, each intended to address problems of residual limb perspiration, with the as-prescribed liner of lower limb prosthesis user and determine their…
- Trial name
- NCT07024342
- Testing
- Liner perforated with very small diameter holes, Liner perforated with somewhat larger diameter holes, Liner-liner
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- VA Puget Sound Health Care System
Substance-Related Disorders
Abuse Liability of Controlled-Release Oxycodone Formulations
The objective of this study is to examine the abuse liability of a single 40mg dose of 2 controlled release oxycodone formulations (Apo-Oxycodone CR® and OxyNEO®) in non-dependent recreational opioid users by assessing the…
- Trial name
- NCT02101840
- Testing
- Apo-Oxycodone CR®, OxyNEO®
- Where
- Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Physical Inactivity, Cerebral Palsy
Effects of Physical Activity on Prescription (PAP) as a Health-enhancing Intervention in People With Disabilities
Physical inactivity is an increasing problem in the general population in society. However, in people with disabilities, inactivity is even more frequently reported.
- Conditions
- Physical Inactivity, Cerebral Palsy, Autism, Autism Spectrum Disorder
- Trial name
- PAP (NCT05867940)
- Testing
- Physical activity on prescription
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Skane
Diabetes Type 2
Impact of a Community Health Worker Strategy on Produce Prescription Program Uptake Among People With Diabetes
Produce prescription programs (PRx) are promising interventions for improving health outcomes for patients with both type 2 diabetes (T2D) and food insecurity, but uptake has been suboptimal.
- Trial name
- NCT06401668
- Testing
- Community health worker (CHW) strategy, PRx Program
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Yale University
Drug Overdose
Pharmacodynamics and Arteriovenous Differences of Naloxone in Healthy Participants Exposed to an Opioid
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. To save lives, immediate treatment with a μ-opioid antidote such as naloxone is required.
- Trial name
- OPI-15-001 (NCT02405988)
- Testing
- Intravenous naloxone, Remifentanil
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Opioid Dependence
Prescription Opioid Abuse Among Pain Patients: Predictors of Relapse
In this study, we will assess opioid self-administration in a laboratory setting in persons with pain who have a history of opioid abuse.
- Trial name
- PAIN (NCT01967641)
- Testing
- buprenorphine/naloxone combination
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- New York State Psychiatric Institute
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