Clinical trials: Prescriptions
Housing Instability, High Emergency Department Utilization
Housing Prescriptions as Health Care
Housing Prescriptions as Health Care is a research project studying the effects of an innovative intervention that combines services across the health, housing, social and legal service sectors in order to improve housing…
- Conditions
- Housing Instability, High Emergency Department Utilization, Medical Complexity
- Trial name
- NCT02816294
- Testing
- Housing Prescription
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Overdose
Evaluation of a Medication Health Center to Promote Opioid Safety
This study will assess the impact of an opioid safety clinic intervention for patients prescribed chronic opioid therapy. Outcomes are visits to the clinic, naloxone dispensings, Prescription Drug Monitoring reviews, and Urine…
- Trial name
- NCT06456294
- Testing
- MHC Outreach Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Kaiser Permanente
Prescribing, Off-Label
CMO Letter to Reduce Unnecessary Antibiotic Prescribing March 2018
This trial aims to reduce unnecessary prescription of antibiotics by general practitioners (GPs) in England. Unnecessary prescriptions are defined as those that do not improve patient health outcomes.
- Trial name
- NCT03582072
- Testing
- letter from the CMO
- Where
- United Kingdom
- Volunteers
- 4,796 people
- Sponsor
- Public Health England
Prescription Drug Abuse (Not Dependent)
Mobile Application for Prescription Drug-Abuse Education (MAPDE)
The aims of this pilot study are: (1) to assess the feasibility and acceptability of a mobile application to educate military members about the risks of prescription drug misuse; (2) to determine if there is evidence that the…
- Trial name
- MAPDE (NCT03165175)
- Testing
- prescription drug-abuse education smartphone application
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Naval Health Research Center
Overdose, Substance Use
Permanent Supportive Housing Overdose Prevention+ Study
This community-partnered study examines a technical assistance intervention designed to help permanent supportive housing agencies implement evidence-based practices to prevent tenant overdose and improve tenant health.
- Trial name
- POP+ (NCT07214519)
- Testing
- TA Intervention
- Where
- United States
- Volunteers
- 2,940 people
- Sponsor
- NYU Langone Health
Opioid-Related Disorders, Opiate Addiction
A Quantitative Study to Assess the Construct Validity of the Prescription Opioid Misuse and Abuse Questionnaire
The purposes of this study are to evaluate the validity and reproducibility of the POMAQ to identify opioid abuse and misuse behaviors among participants who have chronic pain which requires long-term opioid use.
- Conditions
- Opioid-Related Disorders, Opiate Addiction, Narcotic Abuse, Drug Abuse
- Trial name
- POMAQ (NCT02678507)
- Testing
- Prescription Opioid Misuse and Abuse Questionnaire (POMAQ)
- Volunteers
- 800 people
- Sponsor
- Member Companies of the Opioid PMR Consortium
Kidney Stone
Effectiveness of Urinary Alkalinizing Agents on Kidney Stone Risk
Randomized treatment trial of baking soda or LithoLyte to determine if baking soda and Litholyte are effective in raising 24 hour urine citrate and pH.
- Trial name
- NCT04095975
- Testing
- Baking Soda, LithoLyte
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Wisconsin, Madison
Opioid-Related Disorders, Narcotic-Related Disorders
Safe Prescription of Opioids in Primary Care
Opioid analgesics are commonly prescribed addictive narcotics intended for the treatment of pain. Inappropriate prescription of opioids in quantities and for conditions which lack clinical evidence contributes to the risk of…
- Conditions
- Opioid-Related Disorders, Narcotic-Related Disorders, Addiction
- Trial name
- NCT05577026
- Testing
- Educational intervention and prescription feedback, General information on treatment guidelines
- Where
- Sweden
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Cancer Patients, Cancer-related Pain
A Consensus on Opioid Prescription for Oncologic Patients in Latin America - A DELPHI Study.
As seen worldwide, cancer incidence is increasing in Latin America achieving an amount of 1.3 million new cases annually.1 In addition, it is expected that up to 70% of patients with cancer will experience pain2, one of the most…
- Trial name
- NCT04844788
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Instituto do Cancer do Estado de São Paulo
COPD, Spirometry
Evaluation of a Mobile Application to Facilitate the Interpretation of Spirometry by Family Physicians and Residents
Problematic: Spirometry is used to objectify the obstructive syndrome defining chronic obstructive pulmonary disease (COPD). However, this test remains underused in the primary care.
- Conditions
- COPD, Spirometry, Mobile Application
- Trial name
- NCT03206606
- Testing
- SPIRO
- Where
- 8 sites in Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Laval University
Depression, Non-psychotic Diagnosis as Co-morbidity
The Canadian Armed Forces PEER Study
This is a prospective, single-blinded, randomized, multicenter study to evaluate the utility, safety, and efficacy of using PEER Interactive - an EEG-based technology - to inform the prescription of medications to participants…
- Trial name
- PEERCanada (NCT03625271)
- Testing
- The PEER Report
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- MYnd Analytics
Opiate Overdose, Opioid-Related Disorders
Developing and Evaluating a Machine-Learning Opioid Overdose Prediction & Risk-Stratification Tool in Primary Care
This clinical trial aims to evaluate the pilot implementation of a machine-learning (ML)-driven clinical decision support (CDS) tool designed to predict opioid overdose risk within the electronic health record (EHR) system at UF…
- Conditions
- Opiate Overdose, Opioid-Related Disorders, Narcotic-Related Disorders, Substance-related Disorders
- Trial name
- DEMONSTRATE (NCT06810076)
- Testing
- Machine Learning-Based Clinical Decision Support: Overdose Prevention Alert (OPA) Intervention
- Where
- United States
- Volunteers
- 674 people
- Sponsor
- University of Pittsburgh
COVID-19
Awaken Prone Positioning Ventinlation in COVID-19 Patients
Awaken prone positioning (APP) ventilation has been widely accepted as a standard regimen in the management of COVID-19 patients.
- Trial name
- NCT05677984
- Testing
- Awaken prone positioning ventilation
- Where
- China
- Volunteers
- 409 people
- Sponsor
- Southeast University, China
Acute Disease
High-risk Antithrombotic Drugs at Discharge and Consultation for Hemorrhagic or Thromboembolic Events in the Emergency Department
This observational study aims to estimate the proportion of patients discharged from a hospital with a prescription for anticoagulant medication who subsequently visit the emergency department due to an adverse thrombotic or…
- Trial name
- NCT07278648
- Testing
- Antithrombotic therapy
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf
Pain, Chronic, Prescription Drug Abuse (Not Dependent)
Linking Epigenomics With Prescription Opioid Abuse and High Impact Musculoskeletal Pain
Genetic variability from epigenetic modification of genes related to pain physiology and opioid pharmacodynamics may influence susceptibility to high-impact chronic musculoskeletal pain, opioid efficacy, and vulnerability to…
- Trial name
- LEAP (NCT03947749)
- Where
- 2 sites in United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- University of Florida
Type 2 Diabetes Mellitus, Exercise
Project Diabetes: Prescription for Healthy Living
Health disparities related to obesity, pre-diabetes and Type 2 diabetes in the United States represent public health concerns. Given the benefit of exercise in disease prevention and management, evidence-based, cost-effective…
- Conditions
- Type 2 Diabetes Mellitus, Exercise, Obesity, Behavioral Research
- Trial name
- NCT00775216
- Testing
- Behavioral counseling plus "telephone helpline"
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Tobacco Use, Alcohol Abuse
Tobacco, Alcohol, Prescription Drug, and Illicit Substance Use- Electronic Spanish Platform
The goal of this study is to validate the TAPS-ESP as a screen and assessment that can be used in primary care for the screening and treatment of substance use.
- Conditions
- Tobacco Use, Alcohol Abuse, Prescription Drug Abuse, Substance Use
- Trial name
- TAPS-ESP (NCT05476588)
- Testing
- Screening
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Economics, Fraud
The Effect of Informative Letters on the Prescription and Receipt of Opioids
Inappropriate prescribing exposes patients to health risks and results in wasteful public expenditures. This study will evaluate an approach to fighting abusive prescription: sending letters to suspected potentially inappropriate…
- Conditions
- Economics, Fraud, Delivery of Health Care, Health Expenditures
- Trial name
- NCT03202745
- Testing
- Patient Consequences Letter, Prescriber Consequences Letter
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abdul Latif Jameel Poverty Action Lab
Attention Deficit Hyperactivity Disorder, Stimulant Use
Acute Effects of Stimulant Medication in College Students With ADHD
The investigators will examine the acute effects of stimulant medication on executive functioning. The rationale for the proposed study is to examine the efficacy of stimulants for college students with ADHD and help prevent…
- Conditions
- Attention Deficit Hyperactivity Disorder, Stimulant Use, Working Memory, Change in Sustained Attention
- Trial name
- NCT03935646
- Testing
- Adderall IR 10mg
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Wyoming
Overactive Bladder (OAB), Over Active Bladder
A Prospective Evaluation of a Prescription Digital Therapeutic for Treatment of Overactive Bladder in Women: The RiSolve Trial
The RiSolve Trial is a prospective, single-arm, post-market clinical investigation designed to evaluate the effectiveness, usability, and safety of a prescription digital therapeutic (PDTx) for women suffering from overactive…
- Trial name
- NCT07206446
- Testing
- RiSolve
- Where
- Ireland
- Volunteers
- 46 people
- Sponsor
- University of Galway
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