Clinical trials: Prescriptions
Suicide, Firearm Injury
Emergency Room Firearm and Medication Safety Intervention
Seventeen United States Veterans die by suicide each day. Nearly three-fourths of those Veterans die from firearm injury or poisoning, and many seek care in VA Emergency Departments (ED) prior to suicide attempts.
- Conditions
- Suicide, Firearm Injury, Overdose
- Trial name
- NCT04797221
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Metabolic Syndrome X
A Study on the Intervention of Metabolic Syndrome Patients With Exercise Prescription Based on Ventilatory Threshold Using Cardiopulmonary Exercise Test
Analyze the clinical intervention effects and differences of progressive precision exercise prescriptions formulated by two methods for determining exercise intensity on metabolic syndrome (MS).
- Trial name
- NCT06379204
- Testing
- the maximum physiological value standardized group, the ventilatory threshold individualized group
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Taiyuan Central Hospital of Shanxi Medical University
Arthroplasty, Replacement, Hip
Home-based Rehabilitation Following a Total Hip Replacement
In this study we will investigate the relation between performed exercise dose and recovery after total hip replacement (THA). A dose-response relationship is hypothesized.
- Trial name
- PHETHAS-1 (NCT03109821)
- Testing
- Home-based exercise
- Where
- Denmark
- Volunteers
- 94 people
- Sponsor
- Central Jutland Regional Hospital
Naloxone
Increasing Naloxone Access for Persons Who Use Opioids
Deaths relating to opioid overdose have rapidly increased over the past two decades. Due to the serious public health concern of the opioid epidemic, federal agencies recommend employing various harm reduction interventions.
- Trial name
- NCT04303000
- Testing
- Opioid Overdose Education with Naloxone Distribution, Opioid Overdose Education
- Where
- 4 sites in United States
- Volunteers
- 111 people
- Sponsor
- University of Alabama at Birmingham
Breast Cancers, Triple Negative Breast Cancer (TNBC)
Personalizing the Use of Pembrolizumab for Patients Who Have a Strong Response in Early Triple Negative Breast Cancer
OPT-PEMBRO trial is a pragmatic, multicentre, international, prospective, non-inferiority, two-arms, randomised (1:1), open-label, Phase III clinical study.
- Trial name
- OPT-PEMBRO (NCT06606730)
- Testing
- Pembrolizumab, Deescalation
- Where
- 2 sites in Belgium, France
- Volunteers
- 2,454 people
- Sponsor
- UNICANCER
Opioid-Related Disorders, Hepatitis C (HCV)
Kentucky Outreach Service Kiosk (KyOSK): Reducing HIV, HCV, and Overdose Risk
This study will test the effectiveness, implementation outcomes, and cost effectiveness of a locally-tailored, health kiosk to reduce overdose, hepatitis C, and HIV risk behavior and improve linkage to care in rural Appalachia.
- Conditions
- Opioid-Related Disorders, Hepatitis C (HCV), Human Immunodeficiency Virus (HIV), Drug Overdose
- Trial name
- NCT05657106
- Testing
- Health kiosk
- Where
- United States
- Volunteers
- 752 people, healthy volunteers welcome
- Sponsor
- April M Young
Cholecystitis; Acute, With Cholelithiasis
Is an Antibiotic Prescription Required After Laparoscopic Cholecystectomy
The need for antibiotics to reduce surgical site infection after cholecystectomy for acute calculous cholecystitis is still controversial.
- Trial name
- NCT04290104
- Testing
- 1gr oral ampicillin/sulbactam group
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Medical Certificates for Sick Leave and Drug Prescriptions
Effects of Acceptance and Commitment Therapy in Primary Health Care
How does education of health personnel with Acceptance and Commitment Therapy affect the extent of medical certificates of sick leave and drug prescriptions in primary health care centers in Kalmar compared with similar centers…
- Trial name
- ACTPrimary (NCT03737019)
- Testing
- Education with Acceptance and Commitment Therapy, Control, no intervention
- Where
- 2 sites in Sweden
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Drug Overdose
Pharmacokinetics and Pharmacodynamics of a New Formulation of Nasal Naloxone for Prehospital Use
Overdose with potential deadly outcome is a serious problem among opioid abusers, not least in Norway. The annual death toll from overdose is about 250, higher than road traffic accidents.
- Trial name
- OPI-14-001 (NCT02307721)
- Testing
- Intranasal naloxone, Intramuscular naloxone, Remifentanil
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Opioid Use Disorder, Bereavement
Community and Familial Impacts of the Opioid Crisis
This study aims to analyze the needs of those who have lost a loved one to opioid-related death and/or those currently supporting a loved one in treatment for Opioid Use Disorder.
- Conditions
- Opioid Use Disorder, Bereavement, Overdose of Opiate
- Trial name
- NCT05116852
- Testing
- Survey
- Where
- United States
- Volunteers
- 578 people
- Sponsor
- Cambridge Health Alliance
Musculoskeletal Pain
Acetaminophen (APAP) +/- Oxycodone
This is an emergency department based randomized study of oxycodone/ acetaminophen versus acetaminophen alone for patients with acute musculoskeletal pain refractory to ibuprofen
- Trial name
- NCT04122443
- Testing
- Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- Montefiore Medical Center
Knowledge, Attitudes, Practice
Knowledge, Attitude and Practice of Physicians Toward The Prescription of Proton Pump Inhibitors in Egypt
The aim of this study is to identify the knowledge , attitude and practice toward PPI use among doctors in Egypt
- Trial name
- NCT04617990
- Volunteers
- 5,000 people
- Sponsor
- Ahmad Nassar Ibrahim
Respiratory Tract Infection
Antibiotics in Patients With Acute Respiratory Tract Infection With Procalcitonin as Parameter
Antibiotics in patients with acute respiratory tract infections in primary care in consideration of procalcitonin as additive parameter.
- Trial name
- NCT00688610
- Testing
- laboratory value procalcitonin
- Where
- Germany
- Volunteers
- 571 people
- Sponsor
- Hannover Medical School
Opioid Use Disorder, Overdose
Pharmacist-Led Interventions to Increase Access to Medications for Opioid Use Disorders (PLI-MOUD)
The purpose of this study is to investigate the impact of a pharmacist-led intervention to expand access to medications for opioid use disorder (MOUD) on racial/ethnic differences in opioid-related overdose among individuals…
- Trial name
- PLI-MOUD (NCT05776823)
- Testing
- Pharmacist Narcan Training, BIRT, SMC
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- University of Arkansas
Antibiotic Side Effect
Antibiotic Prescription for Children With Acute Upper Respiratory Tract Infections in Assiut District
Antibiotics are one of the most commonly prescribed drugs in pediatric care all over the world. Over prescription of antibiotics is a major public health problem and the most important factor in the emergence of antibiotic…
- Trial name
- NCT04127682
- Testing
- Antibiotic KAP questionnaire
- Where
- Egypt
- Volunteers
- 186 people
- Sponsor
- Assiut University
Non-cancerous Chronic Pain
Comparison of Standard Opioid Prescription Versus Prescription Guided by Pharmacogenetic Analysis in Patients With Non-cancerous Chronic Pain.
The investigators hypothesize that opioid prescription guided by patient pharmacogenetic profile will diminish opioid-associated undesirable effects by 50% and improve medication compliance.
- Trial name
- AlgoPGx (NCT03498014)
- Testing
- Pharmacogenetic analysis allowing personalized opioid prescription, Standard opioid prescription
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Drug Overdose, Opioid-Related Disorders
Pharmacokinetic Evaluation of Intranasal and Intramuscular Naloxone in Healthy Volunteers
To determine the pharmacokinetics of 4 intranasal doses of naloxone compared to a 0.4 mg dose of naloxone administrated intramuscular and to identify an appropriate intranasal dose that could achieve systemic exposure comparable…
- Trial name
- NCT02572089
- Testing
- Naloxone
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Pneumonia
Pilot Study to Study the Time Between Pleuropulmonary Ultrasound and Antibiotic Therapy Prescription in Patients Admitted to the Emergency Department for Suspected Pneumonia
Pneumonia is a common pathology with significant morbidity and mortality. It is recommended in his diagnostic approach to perform either a chest X-ray or a pleuropulmonary ultrasound.
- Trial name
- PRE-EPPA (NCT07703852)
- Testing
- Pleuropulmonary ultrasound performed by the investigator for patient with suspicion od Pneumonia
- Volunteers
- 15 people
- Sponsor
- University Hospital, Grenoble
Opioid Use, Pregnancy
Perinatal Opioid Use
To compare maternal and newborn outcomes among pregnant women with OUD receiving care via telemedicine versus in-person.
- Trial name
- NCT04049032
- Testing
- In-Person Perinatal OUD Treatment, Perinatal OUD Treatment via Telemedicine
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Medical University of South Carolina
Breast Neoplasms
Exercise in Women at Risk for Breast Cancer
This 2-part study will examine how much exercise people usually do in the course of their daily lives and how two different types of exercise-stretching and walking-affect the amount of fat in the body and certain hormones in the…
- Trial name
- NCT00092950
- Testing
- Physical activity
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- National Cancer Institute (NCI)
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