Clinical trials: Prescriptions
Baseline Epidemiologic Assessment
Baseline Epidemiologic Assessment of Abuse-Deterrence of MorphaBond Extended Release (BEAD-MB)
The main objectives of this study are to provide surveillance/descriptive data to (a) assess utilization of MorphaBond ER and selected comparators overall and by age group and census regions using nationally-projected quarterly…
- Trial name
- BEAD-MB (NCT04033094)
- Testing
- MorphaBond ER, Comparator Drug
- Where
- United States
- Volunteers
- 17,566 people
- Sponsor
- Daiichi Sankyo
Prostatic Neoplasms, Exercise
Exercise Prescription Dose for Castration Resistance Prostate Cancer Patients
Recent drug improvement (e.g. abiraterone or enzalutamide) for castration resistant prostate cancer (CRPC) patients has improved survival.
- Conditions
- Prostatic Neoplasms, Exercise, Castration-resistant Prostate Cancer, Physical Activity
- Trial name
- NCT03526562
- Testing
- Exercise
- Where
- Belgium
- Volunteers
- 9 people
- Sponsor
- University Hospital, Ghent
Healthy
Prevention of Potentially Inappropriate Prescribing in Late Life Using Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP) and Screening Tool to Alert Doctors to Right Treatment (START) Criteria
Potentially inappropriate prescribing is common in older patients and encompasses overuse, misuse and underuse of medications. Potentially inappropriate prescribing is associated with negative outcomes including adverse drug…
- Trial name
- NCT00915824
- Testing
- STOPP/START criteria
- Where
- Ireland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cork University Hospital
Multiple Sclerosis, Lung Cancer
An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer
CT-100 is a platform that provides interactive, software based therapeutic components that may be used as part of a treatment in future software-based prescription digital therapeutics.
- Conditions
- Multiple Sclerosis, Lung Cancer, Breast Cancer
- Trial name
- NCT06136923
- Testing
- CT-100-D-004-A, CT-100-D-004-B
- Where
- United States
- Volunteers
- 194 people
- Sponsor
- Click Therapeutics, Inc.
Obesity, Morbid, Drug Use
Evaluation of the Implementation of Drug Prescription Recommendations Using Clinical Decision Support in Patients With Severe Obesity: Retrospective Study
No drug prescription guidelines for severe obesity (BMI>35 kg/m2) are available, leading to non-standardized and / or potentially inappropriate drug management.
- Trial name
- RECOB-MED (NCT06517303)
- Where
- 2 sites in France
- Volunteers
- 1,050 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infections
Improving Post-discharge Antimicrobial Use
One in five hospitalized patients is prescribed an antimicrobial at the time of discharge, and a large proportion of these post-discharge antimicrobials are unnecessary.
- Trial name
- NCT05471726
- Testing
- Prospective audit-and-feedback
- Where
- 5 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Diabetes Type 2
Impact of a Community Health Worker Strategy on Produce Prescription Program Uptake Among People With Diabetes
Produce prescription programs (PRx) are promising interventions for improving health outcomes for patients with both type 2 diabetes (T2D) and food insecurity, but uptake has been suboptimal.
- Trial name
- NCT06401668
- Testing
- Community health worker (CHW) strategy, PRx Program
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Yale University
Chronic Pain
Prescription Opioid Misuse Assessment
Chronic pain is a worldwide health problem due to its high prevalence and its difficult management with a significant impact on quality of life. Pain and addiction co-occur frequently.
- Trial name
- POMA4 (NCT03195374)
- Testing
- Prescription Opioid Misus Index
- Where
- France
- Volunteers
- 951 people
- Sponsor
- University Hospital, Clermont-Ferrand
Physical Inactivity, Cerebral Palsy
Effects of Physical Activity on Prescription (PAP) as a Health-enhancing Intervention in People With Disabilities
Physical inactivity is an increasing problem in the general population in society. However, in people with disabilities, inactivity is even more frequently reported.
- Conditions
- Physical Inactivity, Cerebral Palsy, Autism, Autism Spectrum Disorder
- Trial name
- PAP (NCT05867940)
- Testing
- Physical activity on prescription
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Region Skane
Proton Pump Inhibitor, Primary Care
Proton Pump Inhibitors (PPI): a Study to Improve Appropriate Prescriptions in the Elderly
Proton Pump Inhibitors(PPIs) are the leading evidence-based therapy for upper gastrointestinal disorders and prevention of antiplatelet or non-steroidal anti-inflammatory drugs induced ulcer.
- Trial name
- LAPTOP-PPI (NCT04637750)
- Testing
- Educational intervention
- Where
- 3 sites in Italy
- Volunteers
- 800 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pain, Postoperative, Opioid Misuse
Reduced Opioid Prescription After Laparoscopic Hysterectomy
Given the nationwide epidemic of opioid use and abuse (in part due to over prescription), this study aims at addressing the need for opioid prescription after laparoscopic hysterectomy.
- Conditions
- Pain, Postoperative, Opioid Misuse, Opioid Use, Pain
- Trial name
- NCT05548582
- Testing
- OxyCODONE 5 mg Oral Tablet, Acetaminophen 500 mg Tab, Ibuprofen 600 mg
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Postoperative Pain, Neuropathic Pain
Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement
Spinal surgery is associated with intense pain and associated to a history of preoperative chronic pain. Pregabalin is licensed to treat chronic neuropathic pain, particularly when high dose of opioid are required.
- Trial name
- PREGAB (NCT02866396)
- Testing
- Pregabalin, Naive patient
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Christophe Aveline, MD
Mild Cognitive Impairment
Reshaping the Path of Mild Cognitive Impairment by Refining Exercise Prescription
Dementia is one of the most pressing health care issues of the 21st century. Evidence suggests that exercise enhances cognitive function in healthy older adults. Most research has focused on aerobic training (AT).
- Trial name
- NCT02737878
- Testing
- Aerobic Training, Resistance Training, Balance and Tone Training
- Where
- Canada
- Volunteers
- 226 people
- Sponsor
- University of British Columbia
Cancer
Communicating Multiple Uncertainties Associated With the Benefits and Risks of New Cancer Drugs
This nationally representative randomized survey of US adults will evaluate the effect of using brief statements to communicate multiple different sources of uncertainties about the benefits and harms of new cancer drugs on…
- Trial name
- NCT07110597
- Testing
- Statement communicating 1 source of uncertainty, Statements communicating 2 sources of uncertainties, Statements communicating 3 sources of uncertainties
- Where
- United Kingdom
- Volunteers
- 3,184 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Migraine
Real-world Impact of Erenumab on Sick-leaves, Health Care Resource Use and Comorbidities.
This was a retrospective registry-based study utilizing data collected in association with clinical care of patients. All data was stored in electronic health records at Terveystalo data base, and no patients were contacted for…
- Trial name
- NCT05375097
- Testing
- Erenumab
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Novartis Pharmaceuticals
Drug Overdose, Virtual Reality
Use of Virtual Reality for Overdose Management Educational Trainings
This cluster-randomized trial will compare changes in attitudes and knowledge on administering naloxone based on exposure to either a virtual reality educational training or the current standard educational trainings (e.g.
- Trial name
- NCT04091659
- Testing
- Virtual Reality Education, Standard Education
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Lupus Erythematosus, Systemic, Adverse Effects
Exploration of Genotype Based Personalized Prescription of Cyclophosphamide in Systemic Lupus Erythematosus Treatment
The purpose of this study is to investigate the relationship between the side effects of cyclophosphamide in the treatment of systemic lupus erythematosus (SLE) in Han Chinese and the genetic polymorphisms of drug metabolizing…
- Trial name
- NCT01060410
- Testing
- Polymorphism Analysis, Cyclophosphamide, Pharmacokinetic analysis
- Where
- China
- Volunteers
- 222 people
- Sponsor
- Sun Yat-sen University
Respiratory Tract Infections
Patient Centered Communication Training to Reduce Antibiotic Use in Acute Respiratory Tract Infections
The purpose of this study is to evaluate the effectiveness of a short training program for general practitioners in patient-centered communication to reduce antibiotic prescription for acute respiratory tract infections (ARTI).
- Trial name
- NCT00105248
- Testing
- patient-centered communication training
- Where
- Switzerland
- Volunteers
- 900 people
- Sponsor
- University Hospital, Basel, Switzerland
Obesity, Childhood
Brighter Bites & University of Texas Physicians Produce Rx Extension: Evaluating the Effectiveness of a Prospective Clinical Nutrition Study With Produce Prescriptions
The purpose of this study is to clinically evaluate the effectiveness of an at-home delivery produce prescription in improving weight status and obesity-related health outcomes and to examine the impacts of the program on child…
- Trial name
- NCT06390397
- Testing
- Produce prescription program, Standard of care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center, Houston
Inappropriate Prescribing, Implementation Science
Reduction of Low-value Prescribing Through Audit and Feedback
The objective is to estimate the effect attributable to a primary care pharmacist-led audit and feedback (AF) strategy compared to the currently used AF strategy as a management tool to evaluate healthcare performance focusing on…
- Conditions
- Inappropriate Prescribing, Implementation Science, Behavioral Sciences
- Trial name
- AFFAP (NCT07336550)
- Testing
- Usual AF, Facilitated AF
- Where
- Spain
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
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