Clinical trials: Prescriptions
Osteoarthritis, Sedentary
Swedish PAP in Osteoarthritis - a RCT Study
The purpose of this study is to determine whether an intervention with Physical activity on prescription (PAP) to individuals in primary care with knee or hip osteoarthritis would result in effects on physical activity level…
- Trial name
- NCT02387034
- Testing
- Physical activity on prescription, General advice
- Where
- Sweden
- Volunteers
- 140 people
- Sponsor
- Uppsala University
Overdose, Implementation as Usual
Improving Access to Naloxone to Prevent Opioid Overdose Deaths (SAIA-Naloxone)
The goal of this clinical trial is to compare the effectiveness of a multi-faceted implementation strategy, the Systems Analysis and Improvement Approach for Naloxone (SAIA-N), in syringe service programs (SSPs).
- Trial name
- SAIA-N (NCT05886712)
- Testing
- Naloxone, Usual intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- RTI International
Prescription Drug Problems
SCOSI-M: Preventing Prescription Drug Problems
Brandeis University and University of South Carolina (USC) have joined together to develop the South Carolina Opioid Safety Initiative - Military (SCOSI-M), to develop an academic detailing (medical education) intervention for…
- Trial name
- NCT02210936
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Brandeis University
Opioid-use Disorder
Mobile Medication Adherence Platform for Buprenorphine-Naloxone During Treatment of Opioid Use Disorder: Phase I Study
The investigators will conduct a phase I study involving 41 participants selected randomly among patients prescribed buprenorphine-naloxone for opioid misuse as a feasibility trial of the study of the Pillsy device.
- Trial name
- MAP4BUP (NCT04656899)
- Testing
- Reminders messages to improve adherence.
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Washington State University
Opioid-use Disorder, Opioid Dependence
Young Houston Emergency Opioid Engagement System
The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral…
- Conditions
- Opioid-use Disorder, Opioid Dependence, Opioid Overdose, Opioid Use
- Trial name
- YHEROES (NCT04811014)
- Testing
- Buprenorphine, Naloxone Drug Combination, Individual Counseling, Peer Recovery Support Services
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- The University of Texas Health Science Center, Houston
Nursing Home Residents, Older People
Improved Prescribing for Older Nursing Home Patients
Research aim: To investigate the effect of training health care professionals in medication assessments on the medication use of nursing home residents with a limited life expectancy (< 1.5-2 years).
- Conditions
- Nursing Home Residents, Older People, Prescribing, Advance Care Planning
- Trial name
- IMPETUS (NCT06731361)
- Testing
- Systematic multidisciplinary medication review + ACP (SMMR+)
- Where
- 7 sites in Netherlands
- Volunteers
- 450 people
- Sponsor
- Amsterdam UMC, location VUmc
Malaria
Sustainable Financial Incentives To Improve Prescription Practices For Malaria
This project aims to test an innovative, sustainable financial incentive designed to reduce the number of non-malarial fevers that are treated inappropriately with antimalarial drugs.
- Trial name
- NCT01809873
- Testing
- Performance based incentives
- Where
- Kenya
- Volunteers
- 14,862 people
- Sponsor
- Duke University
Hallux Valgus
Hallux Valgus and Custom Orthotic Prescription
Hallux valgus can be defined as a progressive subluxation of the first metatarsophalangeal joint and lateral deviation of the hallux. This common foot condition is associated with altered gait patterns.
- Trial name
- NCT02386631
- Testing
- Custom Made Orthotic
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Dr. Stephen Perry
Infection
Do Fair Comparisons or Harms Data Increase Responsiveness to Feedback About Antibiotic Prescribing: 2x2 Factorial Trial
Antibiotic overuse is common and antibiotic prescribing contributes to rising rates of antimicrobial resistance. Primary care physicians prescribe the majority of all antibiotics and there is large inter-physician variability in…
- Trial name
- NCT04594200
- Testing
- Audit and Feedback (A&F)
- Where
- Canada
- Volunteers
- 5,107 people
- Sponsor
- Women's College Hospital
Transfemoral Amputation
Personalizing MPK Prescription
In current clinical prosthetic practice, there is no evidence based method for selecting a microprocessor knee (MPK) joint for a patient with an above the knee amputation.
- Trial name
- NCT06399471
- Testing
- Microprocessor prosthetic knee
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Georgia Institute of Technology
Obesity & Overweight, Fat Mass
High-Intensity Interval Training in Low Versus Normal Oxygen: Effects on Body Fat and Gut Health in Adults Aged 50-75 With Overweight or Obesity (HYPOXFAT)
Overweight and obesity are major public health challenges worldwide, and their prevalence increases with age, partly because of age-related metabolic and hormonal changes.
- Trial name
- HYPOXFAT (NCT07796971)
- Testing
- Hypoxic High-Intensity Interval Training, Normoxic High-Intensity Interval Training
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Pain, Postoperative, Orthognathic Surgery
Personalization of Opioid Prescription Following Orthognathic Surgery
This study aims to investigate pain management and satisfaction following orthognathic surgery, which is a type of surgery that corrects jaw and facial bone issues.
- Conditions
- Pain, Postoperative, Orthognathic Surgery, Opioid Use, Patient Satisfaction
- Trial name
- NCT05708521
- Testing
- Personalization of dose and frequency and instituting a tapering protocol of hydromorphone post-orthognathic surgery, Standardized dose and frequency of hydromorphone with no tapering post-orthognathic surgery
- Where
- Canada
- Volunteers
- 201 people
- Sponsor
- Nova Scotia Health Authority
Marijuana Dependence
The Effect of Marijuana and Prescription Medications in Mood, Performance and Sleep
Heavy marijuana users report experiencing trouble sleeping when they try to quit, but this has not been carefully studied. This research is being done to learn more about sleep function in heavy marijuana users, and to determine…
- Trial name
- NCT00893269
- Testing
- eszopiclone, ramelteon, zolpidem
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Amikacin Treatment
Prescription Strategies of Amikacin in Intensive Care Patients on Renal Replacement Therapy: an Observational Prospective Multicenter Study
Amikacin is the aminoglycoside of choice for treatment of severe infections in intensive care. An achievement of its objectives in pharmacokinetics and pharmacodynamics is difficult in intensive care patients because of…
- Trial name
- AMIDIAL-ICU (NCT04322019)
- Testing
- Data record
- Where
- France
- Volunteers
- 112 people
- Sponsor
- CHU de Reims
Type 2 Diabetes Mellitus, Hypertension
Grocery Prescription Program for Medicaid Adults With Hypertension or Type 2 Diabetes
The purpose of this study is to evaluate the effectiveness of a grocery prescription program in adults diagnosed with either Type 2 Diabetes Mellitus or Hypertension. Participants will enroll in Instacart Fresh Funds program.
- Trial name
- NCT06033664
- Testing
- Fresh Funds
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Alison Gustafson
Acquired Brain Injury Including Stroke
Prescription Patterns of Antidepressants, Analgesics, and Antiepileptics Drugs in Adult With Acquired Brain Injury
Acquired brain injury (ABI), primarily caused by stroke and traumatic brain injury (TBI), leads to severe disabilities and requires complex pharmacological management during post-acute rehabilitation.
- Trial name
- PRES'SMR (NCT06983314)
- Testing
- Observation
- Where
- France
- Volunteers
- 201 people
- Sponsor
- University Hospital, Caen
Substance Use, HIV Infections
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)
This study will test the effects of an intervention to reduce substance use and related harms among people leaving rural jails or otherwise involved in the criminal justice system.
- Conditions
- Substance Use, HIV Infections, HCV Infection, Sexually Transmitted Infections (Not HIV or Hepatitis)
- Trial name
- NCT04134767
- Testing
- Health Linkage, Overdose Education
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- April M Young
Hypertension
An Observation Study on the Identification of Prescription Patterns of Lodient Tab(Telmisartan/S-amlodipine)
This study identify prescription patterns of Lodient Tab and evaluate the changes of the hypertension symptoms (BP pressure) who are first prescribed and taking Lodient Tab.
- Trial name
- NCT06214832
- Where
- South Korea
- Volunteers
- 4,000 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Stimulant Overdose
Stimulant Overdose in the Medicaid Population: Who is at Risk, and When Are They at Risk
This project addresses Objective 2 of RFA-CE-21-002: to assess risk and protective factors for illicit stimulant use, use disorder, or overdose that can contribute to the development or adaptation of intervention strategies.
- Trial name
- NCT05976984
- Testing
- Aim 1 (case-cohort study), Aim 2 (case-crossover study), Aim 3 (cohort study)
- Where
- United States
- Volunteers
- 634,939 people
- Sponsor
- University of Pennsylvania
Adverse Drug Effect of Opioids, Adverse Drug Effect of Benzodiazepines
Reducing Concurrent Opioid-Benzodiazepine Prescriptions
The purpose of this effort is to use informative e-mails to improve the process of prescribing of opioids and benzodiazepines within the National Capital Region/Military Health System (NCR/MHS), with the aim of decreasing…
- Trial name
- NCT03887247
- Testing
- E-mail Alert
- Where
- United States
- Volunteers
- 2,234 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
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