Clinical trials: Pressure Flow Study
Bladder Outlet Obstruction
Bladder Outlet Obstruction Observation Using Dynamic Urine Vibration "Holter"
Current gold standard of bladder outlet diagnosis is pressure flow study. This study is invasive time consuming and requires expensive and complex set-up.
- Trial name
- NCT01779349
- Testing
- Dynamic Urine Vibration "Holter"
- Where
- 2 sites in Israel
- Volunteers
- 45 people
- Sponsor
- P. Square Medical Ltd
Hypoxaemia During Surgery, Lung Hyperinflation
HFHO vs CPAP During Thoracic Surgery
A single institutional cross-over study design to compare between high flow humidified oxygen (HFHO) device versus conventional CPAP for non-ventilated lung during thoracic surgery.
- Trial name
- NCT03894072
- Testing
- CPAP, HFHO
- Where
- Thailand
- Volunteers
- 28 people
- Sponsor
- Mahidol University
Laryngoscopy, Apnea
High Flow Oxygen in Patients Undergoing Suspension Laryngoscopy Under General Anesthesia
Patients undergoing suspension laryngoscopy under general anaesthesia have oxygen delivered to their lungs through different methods. Inserting a tube in the trachea is the best means for oxygen delivery.
- Conditions
- Laryngoscopy, Apnea, Anesthesia
- Trial name
- OxALa (NCT03472118)
- Testing
- Nasal High Flow Oxygen
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- CMC Ambroise Paré
Urodynamic Studies, Urodynamics
Urodynamics: Prone Vs. Seated Position
To demonstrate the feasibility of a pressure-flow study using a urinary condom with drainage tube in the sitting and lying position in everyday clinical practice and the comparability of the measured values with the…
- Conditions
- Urodynamic Studies, Urodynamics, Outlet Obstruction
- Trial name
- NCT06864117
- Testing
- Body position during urodynamics
- Volunteers
- 200 people
- Sponsor
- Kantonsspital Winterthur KSW
Glaucoma
Aqueous Suppressant Versus Aqueous Outflow on Ocular Blood Flow
The purpose of this study will be to compare the aqueous production suppressant to aqueous outflow drugs in terms of the response to known vascular parameters.
- Trial name
- NCT01308788
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Indiana University
Healthy
A Physiological Study to Assess Awake Prone Positioning and Respiratory Support in Healthy Volunteers
Awake prone positioning (APP) has been proven to reduce the intubation rate for patients with COVID-19-induced hypoxemic respiratory failure.
- Trial name
- NCT05512585
- Testing
- awake prone positioning with advanced respiratory support (high-flow nasal cannula or continuous positive airway pressure)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Positive-Pressure Respiration, Intrinsic, Critically Ill Patients
A New Monitor to Measure Dermal Blood Flow in Critically Ill Patients: a Preliminary Study
Background: Conditions of reduced perfusion are characterized by redistribution of blood flow away from the skin to more vital organs.
- Trial name
- MDBF-CIP (NCT01794468)
- Testing
- Dermal blood flow measurements
- Where
- Israel
- Volunteers
- 11 people
- Sponsor
- Rabin Medical Center
Coronary Artery Disease, Plaque
Pd/Pa vs iFR™ in an Unselected Population Referred for Invasive Angiography
Instantaneous wave-free ratio (iFR™) is a novel non-hyperaemic index of the functional significance of a coronary stenosis. Previous studies have shown variable levels of correlation with the established hyperaemic index FFR.
- Conditions
- Coronary Artery Disease, Plaque, Atherosclerosis, Fractional Flow Reserve
- Trial name
- VERIFY2 (NCT02377310)
- Where
- United Kingdom
- Volunteers
- 197 people
- Sponsor
- Golden Jubilee National Hospital
Cerebral Blood Flow
Cerebral Blood Flow Using Transfontanelle Ultrasound
We planned to evaluate cerebral blood flow and its association with age, blood pressure, and end tidal carbon dioxide in small pediatric using transfontanelle ultrasound during general anesthesia.
- Trial name
- NCT04070339
- Testing
- transfontanelle ultrasound
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Seoul National University Hospital
Inhalation; Gas
Sevoflurane Wash in Method Using Conventional Flows Versus Low Flows of 0.5L
The goal of this observational study is to to evaluate a technique of initiating Sevoflurane low-flow anesthesia which is simple, has a quick wash-in and minimises gas consumption without compromising the safety when compared to…
- Trial name
- NCT06209112
- Testing
- Sevoflurane
- Where
- Oman
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Royal Hospital, Oman
Lower Urinary Tract Symptoms, Lower Urinary Tract Obstructive Syndrome
EEP in Patients With Urodynamically Proven DU/DA
The aim of this project is to create und evaluate a multicentral, retro-/prospective database for patients with urodynamically proven detrusor underactivity (DU) or acontractility (DA) secondary to a non-neurogenic aetiology, who…
- Conditions
- Lower Urinary Tract Symptoms, Lower Urinary Tract Obstructive Syndrome, Detrusor Underactivity, Detrusor Areflexia
- Trial name
- NCT06452927
- Testing
- Endoscopic enucleation of the prostate
- Volunteers
- 300 people
- Sponsor
- EEPiDuDa Study Group
Vascular Stiffness, Cognitive Change
Blueberry Study Aimed at Improving Cognition and Peripheral Blood Flow
Blueberries are rich in the content of a variety of biologically active chemicals that contribute to their health properties. The consumption of blueberries has beneficial effects on vascular function and brain health and…
- Conditions
- Vascular Stiffness, Cognitive Change, Blood Pressure
- Trial name
- NCT04015258
- Testing
- Blueberries, Blueberry powder, Blueberry components capsules
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Acute Respiratory Failure With Hypoxia, Acute Respiratory Distress Syndrome
The Acute Respiratory Intervention StudiEs in Africa (ARISE-AFRICA) Study
The dearth of Intensive care units in low resource settings portends for poor outcomes amongst patients with acute hypoxemic respiratory failure (AHRF) .
- Conditions
- Acute Respiratory Failure With Hypoxia, Acute Respiratory Distress Syndrome, Acute Lung Injury
- Trial name
- ARISE-AFRICA (NCT04693403)
- Testing
- HFNC, CPAP, Standard Oxygen
- Where
- 17 sites in Uganda
- Volunteers
- 705 people
- Sponsor
- Makerere University
Retina, Ocular Physiology
Effect of Xalacom® (Latanoprost/Timolol) and Combigan® (Brimonidine/Timolol) Fixed Combination on Intraocular Pressure and Ocular Blood Flow in Patients With Primary Open Angle Glaucoma or Ocular Hypertension
Glaucoma is one of the most common causes of blindness in the industrialized nations. For a long time glaucoma has been defined as a disease in which high intraocular pressure (IOP) leads to irreversible optic disc damage and…
- Trial name
- NCT00706927
- Testing
- latanoprost 0.005% + timolol 0,5% fixed combination, brimonidine 0,2% + timolol 0,5% fixed combination
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Vienna
Abnormalities, Hyperlipidemia
Study of the Effects of Blackcurrant Extract and Omega-3 Fats on the Health of the Heart and Blood Vessels
Background: Heart disease is the leading cause of death in the United States. Eating fruits and vegetables with chemicals called flavonoids may protect against heart disease and improve blood flow to the heart.
- Conditions
- Abnormalities, Hyperlipidemia, Cardiovascular Disease, Arteriosclerosis
- Trial name
- NCT02019680
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Cerebrovascular Disorders
The Outcome of Respiratory Muscle Training in Stroke Patients
Stroke survivors commonly have respiratory muscle weakness, swallowing disturbance, general weakness, reduced the daily living activities and short of motivation for rehabilitation.
- Trial name
- NCT03491111
- Testing
- Respiratory muscle training for EMT+IMT, Regular Rehabilitation, Respiratory muscle training for EMT
- Where
- Taiwan
- Volunteers
- 46 people
- Sponsor
- Chang Gung Memorial Hospital
Esophageal Motility Disorders, Gastro-esophageal Reflux
Pressure and Flow Study Before and After Treatments for EMD. The pFlow Study
Pressure and flow (PF) analysis allow a detailed report on the bolus passing for each segment of the esophagus. This approach has evidence in oropharyngeal dysphagia, post reflux surgery dysphagia, gastroesophageal reflux in…
- Trial name
- pFlow (NCT03904004)
- Testing
- Peroral endoscopic myotomy, Neumatic dilatation, Botulinum toxin injection
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Fundacion Miguel Servet
Premature Birth
Using Nasal High Flow From Birth in Premature Infants - a Pilot Study
Recent large studies have shown that not all premature babies need to be intubated (have a breathing tube inserted) and ventilated, nor do they all need to be given lung surfactant routinely.
- Trial name
- NCT01991886
- Testing
- Vapotherm Precision Flow
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Ashford and St. Peter's Hospitals NHS Trust
Respiration; Artificial, Positive-Pressure Respiration
Flow Controlled Ventilation in Cardiac Surgery
This trial investigates effects of individualized (by compliance guided pressure settings) flow-controlled ventilation compared to best clinical practice pressure controlled ventilation in cardiac surgery requiring…
- Trial name
- NCT04306757
- Testing
- Evone, Primus
- Where
- Austria
- Volunteers
- 54 people
- Sponsor
- Medical University Innsbruck
Neonatal Respiratory Distress
A Comparative Study Between Postextubation of Preterm Infants Into High-Flow Nasal Cannulae V.S Nasal Continuous Positive Airway Pressure
The investigators hypothesize that there is a growing trend of the feasibility of HFNC as an alternative to other forms of non-invasive ventilation mechanism to provide continuous distending pressure to preterm infants.
- Trial name
- NCT04051762
- Testing
- High flow nasal cannula vs. Nasal continuous positive airway pressure
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ramy Saleh Morsy