Clinical trials: Pressure Injury
Wound Infection, Surgical
Effect of the Negative Pressure Therapy Dressing Compared With Hydrogel Dressing.
The objective of the study is to measure the efficacy of the use of single-use portable negative pressure therapy (PICO ®) in the prevention of surgical wound infections (SSI) from cardiac surgery under extracorporeal circulation…
- Trial name
- PICO/2019 (NCT04265612)
- Testing
- Pico®" negative pressure dressing, Aquacel Surgical®" hydrogel dressing
- Where
- Spain
- Volunteers
- 253 people
- Sponsor
- Hospital Universitario de Canarias
ARDS (Acute Respiratory Distress Syndrome)
Physiological Effects of APRVplus and TCAV in ARDS
In previous studies, airway pressure release ventilation (APRV) has been proven to be an important respiratory support method for ARDS patients, and various APRV ventilation strategies have been proposed.
- Trial name
- NCT06748807
- Testing
- APRVplus, TCAV
- Where
- China
- Volunteers
- 20 people
- Sponsor
- West China Hospital
Pressure Ulcer
Evaluation of Wound Dressings in the Reduction of Shear- Force
The purpose of this study is to investigate if wound dressings are capable in reducing the effects of shear- force at the skin. With our own shear- force model we are able to apply 19 Newton shear- force combined with 9 newton…
- Trial name
- NCT02348671
- Testing
- shear- force
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Premature Birth, Ventilator Lung; Newborn
sNIPPV Versus NIV-NAVA in Extremely Premature Infants
The aim of this study is to demonstrate a significant decrease in asynchrony with NIV-NAVA using the Servo n ventilator (Getinge, Sweden), as compared to abdominal triggered (Graseby capsule) synchronized nasal intermittent…
- Trial name
- EASYNNEO (NCT04068558)
- Testing
- VNI-NAVA/sNIPPV, sNIPPV/VNI-NAVA
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Skin Abnormalities, Skin; Injury, Superficial
Assessment of an Innovative Air Mattress on Critically Ill Infants
The permanent bedding of critically ill neonates and infants in the pediatric intensive care unit (PICU) for an extended amount of time can result in the development of pressure injuries (PI).
- Conditions
- Skin Abnormalities, Skin; Injury, Superficial, Skin; Ulcer, Decubitus
- Trial name
- Prepicare (NCT06425068)
- Testing
- Exposure of the patient to a novel air mattress., Exposure of the patient to a conventional foam mattress.
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Simon Annaheim
the Study Focuses on Comparing Between Supraclavicular and Axillary Blocks
Ultrasound Guided Axillary Brachial Plexus Block Versus Supraclavicular Block in Emergency Crushed Hand Patients
The current study focused on ultrasound guided brachial plexus block (BPB) which plays an important role in patients with hand trauma either in pain control or for surgical intervention.
- Trial name
- NCT03377985
- Testing
- brachial plexus block
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Medical Device-Related Pressure Injury, Prematurity
Non-Invasive Ventilation Interfaces and Nasal Pressure Injury in Preterm Infants
The goal of this randomized controlled clinical trial is to learn whether different non-invasive ventilation interfaces can prevent medical device-related nasal pressure injury in preterm infants receiving respiratory support in…
- Trial name
- NIV-MDRPI (NCT07521410)
- Testing
- Binasal Prong, Nasal Cannula, Nasal Mask
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Istanbul University - Cerrahpasa
Infection, Wound Healing Problem
Fluid Lavage of Open Wounds (FLOW): Pilot Trial
The purpose of this trial is to investigate whether irrigation solution (soap vs. saline solution), or irrigation pressure (high vs. low) will decrease the rate of infection among patients with open fracture wounds.
- Conditions
- Infection, Wound Healing Problem, Nonunion
- Trial name
- FLOW (NCT01069315)
- Testing
- Type of fluid lavage solution, Type of fluid lavage pressure
- Where
- 9 sites in United States, Canada and 1 more
- Volunteers
- 111 people
- Sponsor
- McMaster University
Head Injury, Intracranial Pathology
Effect of Intrathoracic Pressure Regulation on Decreased Cerebral Perfusion
The purpose of the study is to evaluate the physiological response to application of the Intrathoracic Pressure Regulator (ITPR) in patients with compromised cerebral circulation.
- Conditions
- Head Injury, Intracranial Pathology, Compromised Cerebral Perfusion
- Trial name
- NCT01824576
- Testing
- ITPR
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Advanced Circulatory Systems
Brain Injury, Intracranial Hypertension
Evaluation the Intracranial Volume Pressure Response in Increased Intracranial Pressure
The purpose of this study is to discover a mathematic equation to express the intracranial pressure-volume (P-V) curve and a single indicator to reflect the status of the curve.
- Trial name
- NCT01126658
- Testing
- drainage of cerebrospinal fluid (CSF)
- Where
- Taiwan
- Volunteers
- 41 people
- Sponsor
- Chang Gung Memorial Hospital
Wound Healing
Comparative Study Using Negative Pressure Dressing With & Without Silver Alginate to Promote Healing in Chronic Wounds.
The randomized control trial will be conducted in the Department of Plastic and Reconstructive Surgery at Dr. Ruth K.M. Pfau Civil Hospital Karachi.General population admitted in Civil Hospital Karachi, for wound coverage with…
- Trial name
- NCT05009576
- Testing
- silver alginate, VAC dressing without silver alginate
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Dow University of Health Sciences
Pressure Ulcer
100% Whey Protein Based Diet In Enhancing Pressure Ulcer Healing.
This study seeks to evaluate if a 100% whey protein based diet enhances pressure ulcer healing.
- Trial name
- NCT03995407
- Testing
- Peptamen®, Usual Care
- Where
- Singapore
- Volunteers
- 10 people
- Sponsor
- St Luke's Hospital, Singapore
Spinal Cord Injuries, Hypotension
Impact of Transcutaneous Spinal Stimulation on Blood Pressure and Orthostasis in Spinal Cord Injury
The purpose of this study is to learn whether stimulation applied to the spinal cord through the skin (called transcutaneous spinal stimulation) can help control blood pressure in people with a spinal cord injury.
- Conditions
- Spinal Cord Injuries, Hypotension, Orthostatic Hypotension, Spinal Cord Diseases
- Trial name
- (SCI) (NCT07674511)
- Testing
- Tilt test with stimulation (real-time effects): Intervention 1, 20 sessions of stimulation (Intervention 2)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Acute Respiratory Distress Syndrome (ARDS), Acute Respiratory Failure with Hypoxia
Physiologic Effects of Continuous Positive Airway Pressure and High Flow Nasal Oxygenation in Patients with Acute Respiratory Distress Syndrome.
The acute respiratory distress syndrome (ARDS) consists on a lack of breath due to fluid overload in the lungs that is not produced by a heart desease.
- Trial name
- NCT06694311
- Testing
- CPAP, HFNO 50 L/min
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Ricard Mellado Artigas
Infection Abdominal
Delayed Primary Closure Using Negative Pressure Wound Therapy
Surgical site infection rates for contaminated or dirty laparotomy wounds can be as high as 45%. Surgical management of dirty and contaminated wounds has been controversial in the literature and between surgeons.
- Trial name
- NCT04042259
- Testing
- Abthera, Open adbdomen for post-laparotomy without NPWT device
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin
Pressure Ulcer, Pressure Injury
IDEAL SKIIN CARES Bundle to Prevent Pressure Injury
The study will be a multi-center, triple-blinded, cluster randomized controlled trial (c-RCT) conducted with a three-arm parallel design and a 1:1:1 allocation ratio.
- Conditions
- Pressure Ulcer, Pressure Injury, Bed Sore, Pressure Sore
- Trial name
- IdealSkinCares (NCT06369688)
- Testing
- IDEAL SKIIN CARES bundles, IDEAL SKIIN CARES bundles workshop, Respiratory care workshop
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- Baqiyatallah Medical Sciences University
Pressure Injury, Hospital Acquired Pressure Ulcer
Development of a Nursing Care Bundle to Prevent Pressure Injuries and Its Impact on Rates and Costs
Pressure injuries (PIs) represent a significant clinical complication for patients worldwide and pose financial and quality challenges for healthcare systems.
- Trial name
- NCT06770686
- Testing
- Intervention Group, Control Group
- Volunteers
- 90 people
- Sponsor
- Koç University
Scarring
Prospective Observation of Wound Healing With Prevena Incision Management System
This study aims to assess the quality of wound healing in abdominal scars with and without the Prevena Incision Management System.
- Trial name
- NCT01704924
- Testing
- Prevena, Standard of Care Dressing
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Surgical Wound, Recent, Surgical Wound Leak
Study of Avelle™ Negative Pressure Wound Therapy (NPWT) System
The main questions the study aims to answer are: How much do wounds improve when using the Avelle™ Negative Pressure Wound Therapy System for a maximum of 14 days? How safe is the Avelle™ Negative Pressure Wound Therapy System?
- Conditions
- Surgical Wound, Recent, Surgical Wound Leak, Dehiscence Wound, Trauma-related Wound
- Trial name
- NCT05805046
- Testing
- Negative Pressure Wound Therapy System
- Where
- 4 sites in United States
- Sponsor
- ConvaTec Inc.
Acute Brain Injury, Brain Injuries
Comparison of Two Strategies for Endotracheal Tube Cuff Underinflation Prevention During Invasive Mechanical Ventilation
During invasive mechanical ventilation, maintaining endotracheal tube cuff pressure (Pcuff) around 25 cmH2O is recommended for sealing the upper airways.
- Trial name
- CONTIPRESS (NCT03330379)
- Testing
- Tracoe Smart CuffmanagerTM
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Nantes University Hospital