Clinical trials: Pressure Pain Thresholds
Manual Therapies, Neck Pain
Comparison of the Immediate Effects of Manual Therapy Techniques in Non-Specific Neck Pain
The aim of this study is to investigate the effects of manual therapy techniques on joint range of motion, pain tolerance, grip strength, and functionality in individuals with non-specific neck pain.
- Trial name
- NCT06959160
- Testing
- Atlanto-occipital manipulation, Cervical mobilization, Trigger point therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Halic University
Neck Pain
The Natural History of Upper Trapezius Myofascial Trigger Points: Comparison of Local and Remote Tissue Milieu in Normal Muscle, Latent and Active Myofascial Trigger Points Over Time
This study will use microdialysis to investigate myofascial pain. This pain is characterized by "trigger points" (exquisitely tender spots) in a group of tense muscle fibers that extend from the trigger point to the muscle…
- Trial name
- NCT00042276
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Healthy
The Hypoalgesic Effects of Low Load Blood Flow Restriction Training (BFRT)
A randomized controlled trial comparing the immediate effects of upper limb low-load blood flow restriction training (BFRT) with high load sham-BFRT on hypoalgesia and perceptual response in healthy adults
- Trial name
- BFRT (NCT05446103)
- Testing
- Blood flow restriction training
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of West Attica
Sleep Apnea, Chronic Pain Syndrome
Sleep and Pain Sensitivity
This project will assess patients with diagnosed obstructive sleep apnea, to investigate the impact of poor sleep on central pain mechanisms.
- Trial name
- NCT04246294
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- Denmark
- Volunteers
- 6 people
- Sponsor
- Aalborg University
Cervical Radiculopathy
Effect of Manual Therapy on Sensory Features in Patients With Cervical Radiculopathy
Background \& Purpose: Cervical radiculopathy is a neurological disorder, which commonly results because of nerve compression. There are different types of physical therapy interventions that are used for cervical radiculopathy.
- Trial name
- NCT03328351
- Testing
- manual therapy, Superficial soft tissue massage
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 28 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Trigger Points, Myofascial, Myofascial Trigger Points
Dose Response Effects of Cervical Spinal Manipulative Therapy (SMT) on Pressure Sensitivity of Myofascial Trigger Points
Specific Aim 1: To determine if the effect of cervical spinal manipulation on the pressure pain thresholds in a myofascial trigger point in the infraspinatus muscle can be enhanced and/or extended after a second cervical spine…
- Conditions
- Trigger Points, Myofascial, Myofascial Trigger Points, Myofascial Pain Syndrome
- Trial name
- NCT01418170
- Testing
- cervical spinal manipulative therapy
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Canadian Memorial Chiropractic College
Musculoskeletal Pain, Healthy
Multivariable Recovery After Exercise-induced Muscle Pain in the Forearm Muscles
This study investigates the evolution of sensory, motor and tissue variables following exercise-induced pain in wrist extensor muscles in healthy subjects.
- Conditions
- Musculoskeletal Pain, Healthy, Delayed Onset Muscle Soreness
- Trial name
- NCT04012203
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Sacroiliac Joint Dysfunction
Effects of Stecco Fascial Manipulation Versus Muscle Energy Technique on Pain Pressure Threshold, Range of Motion and Disability Among Patients With Sacroiliac Joint Dysfunction
This study holds significant importance as it directly addresses the need for effective physiotherapy interventions in patients with sacroiliac joint dysfunction, a condition that contributes substantially to lower back pain and…
- Trial name
- NCT07723014
- Testing
- Stecco fascial manipulation, Muscle energy technique
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Pain
The Effects of Pain and the Memory of Pain on Autonomic and Neuromuscular Function
The prevalence of chronic pain has been estimated at 30% in the US and these values may under report the true prevalence of people who experience long term pain as additional research has shown that 73% will have a reoccurrence…
- Trial name
- NCT02269384
- Testing
- Experimental Noxious Stimulus, Memory of Experimental Noxious Stimulus, Memory of Prior Significant Injury
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount St. Mary's College, Los Angeles, CA
Pain, Acute, Muscle Soreness
Analgesic Induces Similar Upper and Lower Body Pain Pressure Threshold Increases
Background: Both health professionals and consumers use menthol-based topical analgesics extensively for the temporary relief of pain from musculoskeletal ailments or injury.
- Conditions
- Pain, Acute, Muscle Soreness, Tendon Injuries
- Trial name
- NCT04677985
- Testing
- Menthol based topical analgesic
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Bronchiectasis, Respiratory Disease
Pain Mechanisms in Patients With Bronchiectasis
Pain mechanisms and their clinical impact in patients with bronchiectasis have not been investigated yet. The aim of the research is to assess the presence of central pain mechanisms in patients with bronchiectasis using the…
- Trial name
- NCT03376204
- Testing
- No intervention
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidad San Jorge
Low Back Pain
Effects of Different Kinds of Exercise in Low Back Pain
Low back pain is considered one of the great global challenges in public health due to its high prevalence. Exercise have been shown to cause an increase in pain thresholds, through the effect known as exercise-induced…
- Trial name
- NCT06330961
- Testing
- Isometric exercise, Aerobic exercise
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Healthy
The Effects of Hamstring Stretching With and Without Neural Load on Flexibility, Maximum Isometric Strength and Tibial Nerve Pressure Pain Threshold
The study will be carried out at the Faculty of Nursing and Physiotherapy of the University of Alcala. The study has been approved by the Animal Research and Experimentation Ethics Committee of the University of Alcalá.
- Trial name
- NCT05344586
- Testing
- Hamstring stretching program with neural load, Hamstring stretching program without neural load
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Jaén
Bruxism
Effects of Different Graston Technique Application Speeds on Trapezius Muscle Stiffness, Pressure Pain Threshold, Pain, and Muscle Oxygenation in Patients With Bruxism
This randomized crossover study aims to address an important gap in manual therapy by examining the acute physiological effects of different Graston Technique application speeds (60 BPM vs.
- Trial name
- NCT07506733
- Testing
- Graston Technique 60 BPM, Graston Technique 120 BPM
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Gazi University
Knee Osteoarthritis
End-range Mobilization on Pressure Pain Threshold
Pain in knee osteoarthritis (OA) represents increased pain intensity due to peripheral and central sensitivity. Pressure pain threshold (PPT) is a widely applied (used) method for measuring the magnitude of peripheral and central…
- Trial name
- NCT04273906
- Testing
- End-range mobilization
- Where
- Hungary
- Volunteers
- 40 people
- Sponsor
- University of Pecs
Pain
Self-reported and Experimental Pain in Patients Undergoing Orthodontic Treatment
Pressure Pain Threshold (PPT) is defined as the minimum force applied to an area that is perceived as pain. PPT is considered an objective measurement tool to assess pain levels.
- Trial name
- NCT06426238
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Midwestern University
Low Back Pain
Kettlebell Swings & Low Back Pressure Pain Threshold
The purpose of this study is to determine whether a high intensity kettlebell workout, utilizing a Tabata protocol format, can decrease objective measures of pain pressure threshold in subjects without low back pain.
- Trial name
- NCT03696615
- Testing
- Tabata Kettlebell Swing Workout, Control
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Neck Pain Musculoskeletal, Work Related Musculoskeletal Disorders
Effects of Aerobic and Combined Exercise on Pain and Fatigue in Workers With Chronic Neck Pain
This randomized controlled trial investigated the acute effects of aerobic exercise (AE) and combined aerobic and cervical-upper extremity resistance exercise (CE) on the pressure pain threshold (PPT), pain perception, and…
- Trial name
- EIH-CNNP (NCT07546838)
- Testing
- Aerobic Exercise, Combined Exercise, Informed Control
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Hacettepe University
Inflammatory Bowel Disease (IBD)
Biophysical Assessments of Acupuncture Points in Inflammatory Bowel Disease
Acupuncture points or acupoints are fundamental to the practice of acupuncture, yet their scientific basis remains unclear. According to traditional explanations of acupuncture, acupoints can become tender or more sensitive to…
- Trial name
- NCT07681895
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Myofascial Pain Syndromes, Myofascial Trigger Point Pain
Kinesio Taping for Upper Trapezius Myofascial Trigger Points
Myofascial pain syndrome is one of the most common causes of musculoskeletal pain, and the upper trapezius is the muscle most frequently affected in the neck and shoulder region.
- Conditions
- Myofascial Pain Syndromes, Myofascial Trigger Point Pain, Neck Pain
- Trial name
- NCT07790042
- Testing
- Kinesio Taping (muscle inhibition technique)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Pamukkale University