Clinical trials: Pressure Ulcers
Pressure Injuries, Pressure Injury
Using Music During Wound Care Among Seniors With Pressure Injuries
Pressure injuries (also known as pressure wounds or bed sores) are increasingly common among older adults living in care homes. These wounds often require regular dressing changes, which can be uncomfortable for some.
- Conditions
- Pressure Injuries, Pressure Injury, Pressure Ulcer (PU)
- Trial name
- NCT07456618
- Testing
- Music listening
- Where
- 11 sites in Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Ulcers, Wounds
SNaP Wound Care System Versus Traditional NPWT Device for Treatment of Chronic Wounds
The purpose of this study is to evaluate a novel negative pressure wound therapy (NPWT) device called the SNaP device compared to a traditional NPWT device for the treatment of lower extremity diabetic and venous ulcer wounds.
- Trial name
- NCT00951080
- Testing
- Traditional NPWT System, SNaP Wound Care System
- Where
- 17 sites in United States
- Volunteers
- 132 people
- Sponsor
- 3M
Spinal Cord Injury, Pressure Ulcers
Development and Feasibility of an Internet Intervention for Adults With Spinal Cord Injury to Prevent Pressure Ulcers
The investigators propose to test the feasibility of iSHIFTup (Internet Skin Health Intervention For Targeted Ulcer Prevention) for adults with spinal cord injury (SCI) to prevent serious pressure ulcers (PrUs) and promote…
- Trial name
- iSHIFTup (NCT01885962)
- Testing
- iSHIFTup
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Obesity, Airway
Efficiency of I-gel Supraglottic Airway Device in Supine and Lateral Decubitus Position in Obese Patient
Obesity is linked to many complications of respiratory care which are directly related to the obstructive apnea syndrome: difficult airway management including difficult mask ventilation, difficult intubation and obstruction of…
- Trial name
- NCT04119245
- Testing
- I-gel supraglottic airway device
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Respiratory Insufficiency, Pressure Injury
Effectiveness of Platform-Based Lateralization Therapy in Reducing Interface Pressure Between The Patient And The Support Surface
Pressure injury (PI) is characterized as damage to the skin and/or underlying tissues resulting from sustained pressure or a combination of pressure and shear forces between the patient and the support surface.
- Conditions
- Respiratory Insufficiency, Pressure Injury, Intensive Care Medicine, ARDS
- Trial name
- PREVENT-ICU (NCT06819943)
- Testing
- Automated Lateral Rotation Therapy
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo General Hospital
Diabetes, Diabetic Foot
10 Years Follow-up Study of Plantar Pressure, Kinetics and Kinematics in a Cohort of Patients Diagnosed With Diabetes
A combination of diabetes and neuropathy can cause an altered gait, increased tissue stiffness, limited joint mobility, muscle weakness, foot deformities, thus leading to excessive plantar pressure.
- Conditions
- Diabetes, Diabetic Foot, Plantar Ulcer, Neuropathy
- Trial name
- Diab10 (NCT04054076)
- Testing
- Prefabricated insoles, Soft custom-made insoles, Hard custom-made insoles
- Where
- Sweden
- Volunteers
- 224 people
- Sponsor
- Sahlgrenska University Hospital
Pressure Ulcer, Wound
Insulin Complexation With Hydroxypropyl-beta-cyclodextrin: Use of the Complex in Gel for Healing of Pressure Ulcers
The coprecipitation method was used to prepare hydroxypropyl-beta-cyclodextrin complexed with insulin (HPβCD-I) by mixing insulin with hydroxypropyl-beta-cyclodextrin (HPβCD) in the molar ratio of 1:5 with the addition of 10 mL…
- Trial name
- NCT02418676
- Testing
- Gel with HPβCD-I complex, Gel with insulin, Control gel
- Volunteers
- 15 people
- Sponsor
- State University of Maringá
Postoperative Pressure Ulcer
Peri-operative Risk Factors for Postoperative Pressure Ulcer in Surgical Patients
The aim of this retrospective study is to overall evaluate and validate preoperative and intra-operative risk factors for postoperative pressure ulcers in critically ill postoperative patients.
- Trial name
- NCT02279355
- Volunteers
- 126 people
- Sponsor
- Yonsei University
Pressure Injury
Telemedicine Wounds
This study aims to explore the effectiveness of the flipped education model applied to distance digital learning in enhancing the pressure injury staging interpretation skills of long-term care nursing staff.
- Trial name
- Staging (NCT06827925)
- Testing
- Distance Digital Learning
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Asia University
Diabetic Foot Ulcer
Evaluating Plantar Foot Pressure in a Novel Diabetic Offloading Device
The impacts from diabetes are both patient related and healthcare based. Offloading is recognised as the priority treatment for healing neuropathic and neuro-ischaemic plantar foot ulcers.
- Trial name
- NCT04336176
- Testing
- PulseFlow DF boot, Usual standard of care
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Leeds
Pressure Ulcer
Efficacy and Safety of MedifoamⓇ and BetafoamⓇ in Pressure Ulcer
This study aims to exploratively assess the efficacy and safety of hydrophilic polyurethane foam dressing (MedifoamⓇ or BetafoamⓇ) in pressure ulcer specifically. The target enrolment is 20 patients, with 10 patients per arm.
- Trial name
- NCT02863263
- Testing
- Foam Dressing, Foam Dressing with Povidone Iodine
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Mundipharma Pte Ltd.
Pressure Ulcer
Peripheral Perfusion and Oxygenation in Areas of Risk of Skin Integrity Impairment Exposed to Pressure Patterns.
Objectives: 1. To analyze the changes in peripheral tissue oxygenation in tissues subjected to different pressure regimes in healthy humans. 2.
- Trial name
- POTER-DIC (NCT02736838)
- Testing
- tcpO2, Laser Doppler
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Pressure Injury
Explainable AI for Prospective Pressure Injury Staging
This prospective observational mixed-methods study aims to develop and evaluate an explainable artificial intelligence model for staging pressure injuries using standardized clinical photographs and expert panel-labeled images…
- Trial name
- NCT07891689
- Where
- Turkey (Türkiye)
- Volunteers
- 415 people
- Sponsor
- hatice akaltun
Medical Device Site Injury, Nasogastric Tube
Effect of Evidence-Based Skin Care and Hydrocolloid Dressing in the Prevention of Nasogastric-Related Pressure Injury
This study was planned as a prospective randomized controlled clinical trial to determine the effect of evidence-based skin care interventions and hydrocolloid dressings in preventing nasogastric induced pressure injuries in…
- Conditions
- Medical Device Site Injury, Nasogastric Tube, Pressure Injury
- Trial name
- NCT04682925
- Testing
- skin care arm of where evidence-based practices in the implementation guide, hydrocolloid (Convatec Granuflex-extra thin) dressing, control
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- MAİDE YEŞİLYURT
Stage IV Pressure Ulcer, Diabetic Foot Osteomyelitis
Expanded Access Program (EAP) STIMULAN VG
Individual (single) patient expanded access may be considered.
- Trial name
- EAPSTIMVG (NCT06808568)
- Testing
- STIMULAN VG
- Sponsor
- Biocomposites Ltd
Pressure Ulcer
A Multicentre Clinical Test of the Ultracore Repose® Mattress to Prevent Pressure Ulcers Cat. II-IV in Nursing Homes
A mixed method desgin study will be conducted to study pressure ulcer incidence Cat. II-IV (including deep- tissue injury,unstageable), not associated with the use of medical devices, on the Ultracore Repose® mattress (Frontier…
- Trial name
- NCT04625348
- Testing
- Ultracore Repose® mattress, experiences and perceptions of healthcare workers
- Where
- 5 sites in Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Non-healing Wound
Treatment of Wounds Using Oasis® ECM
The purpose of this clinical study is to gather post-market clinical evidence on the use of Oasis ECM as a treatment for donor site wounds in the community setting in the United Kingdom.
- Trial name
- NCT03632031
- Testing
- Oasis Extracellular Matrix, Standard Care (in control arm)
- Where
- 2 sites in United Kingdom
- Volunteers
- 41 people
- Sponsor
- Cook Biotech Incorporated
Pressure Injury Prevention
Evaluation of Commercially Available Heel Pads for the Prevention of Pressure Ulcers: An Observational Study of Incidence and Usability in Adult Surgical Patients.
This study will evaluate the incidence of heel pressure ulcers in adult patients undergoing elective surgery while using the Oasis Elite Heel Pad (EL130) as part of routine pressure ulcer prevention.
- Trial name
- NCT07852897
- Testing
- Oasis Elite Heel Pad (EL130)
- Where
- Ireland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Trulife
Lower Limb Amputation Below Knee (Injury)
R21: An Easy-to-use, iNtelligent, Affordable LinEr (ENABLE) System for Socket Fit Assessment
Lower limb amputees (LLA) rely on their prosthetic legs to remain active and lead an independent life. For most LLAs, a well-fitted prosthetic socket is the only option to interface with their prosthetic leg, however, it is a…
- Trial name
- ENABLE (NCT05425810)
- Testing
- Apply ENABLE sensing pad, Insert small pads at pressure tolerant locations
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- North Carolina State University
Diabetic Foot
ViscoTurf - Preventing Secondary Diabetic Foot Ulceration.
Diabetic Foot Ulceration (DFU) is one of the most common complication of diabetes costing the NHS over £970m annually. Management of foot ulcers is time-consuming and expensive with 45% taking more than six months to heal.
- Trial name
- NCT04630795
- Testing
- ViscoTurf insole, Control insole
- Volunteers
- 30 people
- Sponsor
- Staffordshire University