Clinical trials: Pressure Ulcers
Pressure Ulcer, Skin Ulcer
Washcloths Effectiveness in Preventing Pressure Ulcers
A monocentric cluster-crossover design has been used in this study to test the effectiveness of a 3-in-1 perineal care washcloth versus standard of care (e.g., water and pH neutral soap) to prevent and treat pressure ulcers in…
- Trial name
- Bathing (NCT03445975)
- Testing
- 3-in-1 perineal care washcloths
- Where
- Italy
- Volunteers
- 240 people
- Sponsor
- Ospedale San Donato
Pressure Ulcers
P400 for Stage II-IV Pressure Ulcers in Home and Extended Care
To assess the efficacy of a pressure ulcer treatment mattress, the P400 mattress, in the treatment of multiple Stage II or one or more large Stage III or IV pressure ulcers in the home care and extended care (nursing home)…
- Trial name
- P400 (NCT01139879)
- Testing
- P400 mattress
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Hill-Rom
Diabetic Foot, Venous Ulcer
Adipose Derived Regenerative Cellular Therapy of Chronic Wounds
Our study aims to explore the effects of Adipose Derived Stem Cells (ASCs) on chronic wounds.
- Conditions
- Diabetic Foot, Venous Ulcer, Pressure Ulcer
- Trial name
- NCT02092870
- Testing
- Adipose derived stem cells
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Tower Outpatient Surgical Center
Injury of Trachea, Friction and Pressure Injuries
The Ornge Comparison of Tracheal Occlusion Pressures to Ensure Safety Trial
Patients who are intubated (breathing tube in windpipe) are often transported by air ambulance. Changes in atmospheric pressure during flight may cause pressure increases in the air-filled cuff holding the tube in the windpipe.
- Conditions
- Injury of Trachea, Friction and Pressure Injuries, Barotrauma, Transfer/Transport Injury
- Trial name
- OCTOPUS (NCT01384500)
- Testing
- Saline in tube cuff
- Where
- Canada
- Sponsor
- Ornge Transport Medicine
Pressure Ulcer
Fluid Immersion Simulation (FIS) System Versus Air Fluidized Bed (AFB) System for Pressure Ulcers
The primary objective is to compare the efficacy of the FIS on closure rate to the AFB after 2 weeks of operative debridement and closure.
- Trial name
- NCT03522714
- Testing
- Fluid Immersion Simulation System, Air Fluidized Bed System
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Pressure Ulcer
Pressure Redistributing Overlay With Targeted Cooling Technology (PRO-TECT) for Pressure Ulcer Prevention
Objective - To demonstrate the efficacy of the pressure redistributing cooling mattress overlay compared to usual care in mitigating the progression of early pressure ulcers in critically ill (ICU) patients via a prospective…
- Trial name
- NCT02634892
- Testing
- PRO-TECT
- Sponsor
- David Brienza
Partial-thickness Burn, Ulcer
NPWT PRO vs KCI Ulta® NPWT and to Compare NPWT PRO vs NPWT PRO With Simultaneous Irrigation on Wound Healing
This study is designed to assess the efficacy and economics of two NPWT (negative pressure wound therapy) branded devices of wound healing outcomes.
- Trial name
- NCT02519621
- Testing
- NPWT PRO without irrigation, NPWT PRO with irrigation, KCI Ulta
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Larry Lavery
Pressure Ulcers Stage III, Pressure Ulcer, Stage IV
The Use of an Oral Mixture of Arginine, Glutamine and Beta-hydroxy-beta-methylbutyrate for Treatment of Pressure Ulcers
To investigate whether an oral nutritional supplement of a mixture of arginine, glutamine and HMB for a maximum period of four weeks is more beneficial than the standard dietary approach to the healing of pressure ulcers, and to…
- Trial name
- NCT03038490
- Testing
- ABOUND
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- Our Lady of Maryknoll Hospital
Pulmonary Malformations, Child
Impact of Forced Expiration On Pleural Drainage Duration (KPDP)
Following thoracic surgery, pleural effusion in pleural cavity requires post-operative drainage. Pleural effusion is responsible for pulmonary congestion, atelectasis, hypoventilation, lower efficacy of diaphragmatic curse, lower…
- Trial name
- KPDP (NCT02660203)
- Testing
- Forced expiration
- Where
- 10 sites in France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Tours
Leg Ulcer
A Randomised Controlled Trial Comparing Vacuum Assisted Closure (V.A.C.®) With Modern Wound Dressings
Current treatment modalities for chronic leg ulcers are time consuming, expensive, and only moderately successful. Recent data suggest that creating a sub-atmospheric pressure by Vacuum Assisted Closure (V.A.C.®) therapy supports…
- Trial name
- NCT00243620
- Testing
- Vacuum therapy (device)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Maastricht University Medical Center
Type IV Pressure Ulcers, Chronic Wounds
Autologous Bone Marrow Stem Cells in Pressure Ulcer Treatment
The aim of the study is to determine the safety and feasibility of an autologous mononuclear stem cells infusion in pressure ulcers of paraplegic patients; and moreover, to evaluate the efficacy of the treatment.
- Conditions
- Type IV Pressure Ulcers, Chronic Wounds, Spinal Cord Injury
- Trial name
- NCT01572376
- Testing
- Infusion of autologous bone marrow stem cells after wound debridement.
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario Central de Asturias
Reduction, Emergencies
Reduction of Anterior Glenohumeral Dislocation in Ventral Decubitus Versus Dorsal Decubitus Under Procedural Sedation
The anterior glenohumeral dislocation is frequently encountered in emergency medicine. It represents about 50% of the total dislocation and affects 1 resident for 10 000 in France.
- Conditions
- Reduction, Emergencies, Anterior Shoulder Dislocation
- Trial name
- EPOLUX (NCT04823689)
- Testing
- reductions
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Hopital Nord Franche-Comte
Decubitis Ulcer
Correlation Between Wound Volume and Depth of Decubitus Ulcers And Resting Energy Expenditure
Patient nutritional needs vary depending on several factors including age, sex, height, weight, injury and co-morbidities. Since injury affects energy expenditure in patients, this must be taken into account when assessing…
- Trial name
- NCT01274650
- Testing
- Indirect Calorimetry
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Paul Edwards
Public Health Nursing
The Effect of Carer Training on Pressure Ulcers in Palliative Patients
The aim of this article is to examine the effect of the training of carers caring for palliative care patients on the prevention and management of pressure ulcers.
- Trial name
- NCT06565949
- Testing
- Education group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Firat University
Burn Wound, Pressure Ulcers Stage II
Study to Evaluate the Performance and Safety of the Medical Device Argogen
A wound, i.e., a break in the skin, can result from several reasons. Pressure ulcers (also called pressure sores, bed sores and decubitus ulcers) are localized damage to the skin and underlying soft tissue usually over a bony…
- Conditions
- Burn Wound, Pressure Ulcers Stage II, Pressure Ulcers Stage III
- Trial name
- NCT05649332
- Testing
- Argogen (silver zeolite powder)
- Where
- 2 sites in Romania
- Volunteers
- 58 people
- Sponsor
- Signorini Medicale S.r.l.
Pressure Ulcers (Hospital-acquired Pressure Injuries)
Sacrum Pressure Injury Prevention Study Using ALLEVYN◊ Complete Care in Adults at Risk of Developing Hospital-acquired Pressure Injuries in Critical Care Units
The purpose of this study is to investigate the use of ALLEVYN◊ COMPLETE CARE Sacrum dressing for the prevention of hospital-acquired pressure injuries in adults.
- Trial name
- PACCT (NCT07849387)
- Testing
- ALLEVYN◊ COMPLETE CARE Sacrum
- Where
- 3 sites in United States
- Volunteers
- 330 people
- Sponsor
- Smith & Nephew, Inc.
Diabetic Foot Ulcer, Venous Leg Ulcer
DETEC® pH Point of Care Wound Diagnostic Test
The purpose of this study is to determine the relationship between wound alkalinity and the non-healing status of chronic ulcer wounds.
- Conditions
- Diabetic Foot Ulcer, Venous Leg Ulcer, Pressure Ulcer, Wound, Non-Healed
- Trial name
- NCT04614038
- Testing
- DETEC® pH
- Where
- 2 sites in United States
- Volunteers
- 450 people
- Sponsor
- Progenitec Inc.
Emergency, Pain
Tissue Interface Pressures in Athlete Medical Extraction
This study aims to establish clinical evidence for the use of scoop stretchers in the sports setting for spinal immobilisation and transport compared to the traditionally used long back boards through measuring tissue interface…
- Conditions
- Emergency, Pain, Medical Device Discomfort
- Trial name
- NCT02770638
- Testing
- Scoop Stretcher, Long Back Spinal board
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Nottingham