Clinical trials: Preterm, Infant
Hypoxic Respiratory Failure With Pulmonary Hypertension
Inhaled Nitric Oxide (INO) In Hypoxic Respiratory Failure
This Phase 3, Double-blind, Randomized, Placebo controlled, multicenter study is to confirm the efficacy of inhaled nitric oxide for the management of hypoxic respiratory failure associated with pulmonary hypertension in preterm…
- Trial name
- NCT00922532
- Testing
- Inhaled Nitric Oxide
- Sponsor
- Mallinckrodt
Bronchopulmonary Dysplasia, Death
Systemic Management in Extremely Preterm and Extremely Low Birth Weight Infants
to estimate incidences of major complications, such as bronchopulmonary dysplasia, death, and delivery room resuscitation among extremely preterm and extremely low birth weight infants in Northern China
- Trial name
- NCT06082414
- Testing
- no interventions
- Where
- China
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Peking University
Premature Infant, Mother-Baby Synchrony
Reading Stories to Premature Babies Reinforces Mother-baby Synchronies?
Observations of the early interactions between the infant and his parents highlighted the existence of rhythmic and reciprocal communications that serve as a basis for the mother-baby relationship and the emotional and cognitive…
- Trial name
- SynchroPrema (NCT03114644)
- Testing
- Physiologically evaluate the impact of reading history on the mother-baby synchronies in a context of premature birth requiring hospitalization in neonatal medicine.
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Premature Infant, Respiratory Insufficiency
Comparison of Oxygen Controllers in Preterm InfanTs
Premature infants often receive respiratory support and supplemental oxygen for a prolonged period of time during their admission in the NICU.
- Conditions
- Premature Infant, Respiratory Insufficiency, Hypoxia, Hyperoxia
- Trial name
- COCkPIT (NCT03877198)
- Testing
- Automated oxygen control by the CLiO2 algorithm, Automated oxygen control by the Oxygenie algorithm
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- Leiden University Medical Center
Patent Ductus Arteriosus in Preterm Infants
The Effectiveness of Paracetamol Versus Ibuprofen in Management of Patent Ductus Arteriosus in Preterm Neonates
This study aims to find and compare the effectiveness of paracetamol and ibuprofen in the closure of patent ductus arteriosus in preterm neonates.
- Trial name
- NCT06601114
- Testing
- Paracetamol Group, Ibuprofen group
- Where
- Pakistan
- Volunteers
- 254 people
- Sponsor
- Arooj Khan
Apnea of Prematurity
CO2 Inhalation as a New Treatment Modality for Apnea of Prematurity
The objective of the present proposed study is to discover whether, in the nursery setting, administration of low concentration inhaled CO2 (0.8%) for a prolonged period (3 days) can make breathing more regular with less apneic…
- Trial name
- NCT01066728
- Testing
- CO2 inhalation, Theophylline
- Where
- 2 sites in Canada
- Volunteers
- 87 people
- Sponsor
- University of Manitoba
Cardiovascular Diseases, Defect, Congenital Heart
Management of Patent Ductus in Premature Infants
To evaluate the effects (up to one year of age) of indomethacin on the clinical course of patent ductus arteriosus (PDA) in premature infants (24 hours old or less) and to assess the relative merits of indomethacin and surgery in…
- Conditions
- Cardiovascular Diseases, Defect, Congenital Heart, Ductus Arteriosus, Patent, Heart Diseases
- Trial name
- NCT00000494
- Testing
- indomethacin, surgery, cardiovascular
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Parenting, Preterm Infants
Training Parenting Self-efficacy in Parents of Hospitalized Preterm Neonates
In a hospital environment, initial parenting of a family with a preterm neonate will be very different than expected. This unusual and stressful situation may determine the self-confidence perceived by mothers and fathers in…
- Conditions
- Parenting, Preterm Infants, Training Support
- Trial name
- CAP-PREM (NCT02803866)
- Testing
- Training program CAP-PREM
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Retained Fetal Lung Fluid
Accuracy of Amniotic Fluid Lamellar Body Counting for Evaluating of Fetal Lung Maturity
The purpose of this study is to determine the accuracy of Amniotic fluid Lamellar Body Counting for Evaluating of Fetal Lung Maturity.
- Trial name
- NCT01463722
- Testing
- Amniotic fluid Lamellar Body Counting
- Where
- Iran
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Hyaline Membrane Disease, Transient Tachypnea
Antenatal Corticoid Therapy for Late Preterm Babies
This study aims to determine the effectiveness of antenatal corticosteroid therapy in late preterm babies. The investigators hypothesis is corticoid accelerates fetal lung maturation even after 34 weeks and reduces risk of…
- Trial name
- ACTLPT (NCT00675246)
- Testing
- Betamethasone
- Where
- Brazil
- Volunteers
- 320 people
- Sponsor
- Instituto Materno Infantil Prof. Fernando Figueira
Parents, Sleep
The Effect of Hypnotherapeutic Sound-files on the Sleep of Parents in the Neonatal Unit.
The goal of this randomised study is to learn about, the effect of hypnotherapeutic sound-files on the sleep of parents of infants in the neonatal unit.
- Conditions
- Parents, Sleep, Infant, Premature, Hypnosis
- Trial name
- NCT05808088
- Testing
- Hypnotherapeutic sound-files
- Where
- Denmark
- Volunteers
- 45 people
- Sponsor
- University of Aarhus
Thyroid, Gland; Functional Disturbance
Ultrasound and Functional Thyroid Evaluation
Thyroid disorders are most commonly concomitant with prematurity and still remains a controversial topic. The incidence of a temporary form of hypothyroidism among preterm neonates is higher than in the general population.
- Trial name
- NCT04208503
- Testing
- thyroid ultrasound
- Where
- 2 sites in Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Anxiety
Organizing the Information Given to Parents of NICU Infants in Order to Reduce Their Anxiety
Being a parent to a premature infant in NICU is an anxious state. Parents ask a lot of questions, and look for information all the time. Organizing the information given to parents could reduce their anxiety.
- Trial name
- NCT00699127
- Testing
- Lecture
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Premature, Premature Birth
Parental Participation on the Neonatal Ward - the neoPARTNER Study
Objective: To investigate the effect of FCR as part of the FICare principles during hospital stay, on parental stress at discharge in parents of preterm or ill infants admitted to the neonatal ward for >7 days as compared to…
- Conditions
- Premature, Premature Birth, Prematurity, Perinatal Problems
- Trial name
- neoPARTNER (NCT05343403)
- Testing
- Family Integrated Care
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Infant, Premature, Diseases
Evolution of Food Orality in Children Aged Between 24 and 36 Months: Comparison of the Severity and Specificities of Disorders Between Two Populations of Children, Born Very Prematurely and Born at Term
Oral disorders are currently widely described in the premature birth population, but few studies compare them to their prevalence in the full-term population.
- Trial name
- EvOral (NCT03860142)
- Testing
- Archet scale
- Where
- France
- Volunteers
- 79 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Infant, Extremely Premature
A Quality Improvement Initiative to Increase Breast Milk Use in a Chinese NICU: a Pilot Study
To assess the prevalence of breast milk feeding in a NICU in China, to implement a quality improvement program to increase breast milk feeding, and to evaluate its impact.
- Trial name
- NCT02897388
- Testing
- breast milk consume promotion
- Volunteers
- 325 people
- Sponsor
- Children's Hospital of Fudan University
Respiratory Distress Syndrome
Effects of Flow Magnitude on Cardiorespiratory Stability During Nasal High Flow Therapy in Preterm Infants
Premature babies often need help breathing for a longer period of time. Traditionally, this is done with a breathing aid called NCPAP (nasal continuous positive airway pressure).
- Trial name
- MASTER (NCT05908227)
- Testing
- NHF high, NHF low, NCPAP
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 150 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Respiratory Distress Syndrome, Newborn, Pulmonary Ventilation; Newborn, Abnormal
Continuous Monitoring of Lung Ventilation
Background: Patients that suffer from respiratory failure and need mechanical ventilation are at risk of further deterioration due to complications induced by progression of lung disease or the mechanical ventilation.
- Conditions
- Respiratory Distress Syndrome, Newborn, Pulmonary Ventilation; Newborn, Abnormal, Apnea, Respiration Disorders
- Trial name
- NCT00810186
- Where
- 3 sites in Israel
- Volunteers
- 77 people
- Sponsor
- Pneumedicare Ltd.
Oral Disorders
Acquisition of Full Oral Feeding and Further Oral Disorders in Extremely Preterm Infants
Extremely premature infants (born before 29 weeks) frequently present oral disorders. The management of these patients require assisted ventilation, enteral nutrition, and intensive daily care (procedural pain, exposure to pain…
- Trial name
- ORAPREM (NCT06648083)
- Testing
- Food autonomy
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Hospices Civils de Lyon
Premature Birth, Bronchopulmonary Dysplasia
Assessment of Lung Structure and Function of Infants Born Prematurely
The purpose of this study is to evaluate the growth of the lung and how easily gas can be taken up by the lung in healthy infants born at full term without any breathing problems and infants born prematurely.
- Conditions
- Premature Birth, Bronchopulmonary Dysplasia, Asthma
- Trial name
- NCT00422305
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Indiana University