Clinical trials: Preterm Labor, Premature Birth
Pain, Newborn
The Effects of Different Procedures on Pain Levels at Preterm and Term Infants in Neonatal Intensive Care Unit
Accurate assessment of pain in neonates in the neonatal intensive care unit (NICU) is vital because of the high prevalence of painful experiences, including both daily procedural pain and postoperative pain, in this population.
- Conditions
- Pain, Newborn, Preterm, Term
- Trial name
- PAIN (NCT05077345)
- Where
- Turkey (Türkiye)
- Volunteers
- 196 people
- Sponsor
- Sanko University
Neonatal Hypoglycemia, Neonatal Hyperglycaemia
Glucose Disturbances in Premature Infants and Quality of Life
The aim of this study is to investigate the correlation between preterm birth, glucose level in the first two hours of life and health related quality of life in the age of 8 months and 7 years
- Trial name
- NCT04770636
- Where
- Croatia
- Volunteers
- 150 people
- Sponsor
- Clinical Hospital Center Rijeka
Preterm Birth
Pessary in Singleton Gestations With Short Cervix Without Prior Preterm Birth
Spontaneous preterm birth (SPTB) remains the number one cause of perinatal mortality in many countries, including the United States.
- Trial name
- NCT02716909
- Testing
- Cervical pessary
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Federico II University
Prematurity
Human Milk Cream as a Caloric Supplement in Pre-Term Infants
Human milk is commonly considered to have 20 calories per ounce (kcal/oz). However, studies show that up to 65% of human milk may be less than the expected 20 kcal/oz which can greatly affect an infant's growth.
- Trial name
- NCT01487928
- Testing
- Human Milk Cream
- Where
- 2 sites in United States
- Volunteers
- 78 people
- Sponsor
- Baylor College of Medicine
Puerperium, EFTs
Fatigue, Anxiety, and Mother-Baby Bonding and Emotional Freedom Technique
Fatigue, Anxiety, and Mother-Baby Bonding and Emotional Freedom Technique
- Trial name
- EFT (NCT06997211)
- Testing
- EFT
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Preterm Birth, Parent-Child Relations
Skin-to-skin Contact in Neonatal Intensive Care Unit (NICU), Caregiving Touch and Neural Correlates of Slow Stroking Touch in Preterm Infants
Preterm (PT) infants spend their first weeks of life in Neonatal Intensive Care Unit (NICU) where receive little affective physical contact, which plays a crucial role in brain development.
- Trial name
- NCT04293939
- Testing
- Functional Magnetic Risonance Imaging (fMRI) acquisition
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Premature Birth
Interpregnancy Care Project-Mississippi (IPC-M)
The IPC program will enroll women who deliver Very Low Birth Weight babies (stillborn or liveborn) at University of Mississippi Medical Center and women who have Very Low Birth Weight babies that receive treatment in the Neonatal…
- Trial name
- IPC-M (NCT00852319)
- Testing
- Interpregnancy Care
- Where
- 3 sites in United States
- Volunteers
- 264 people
- Sponsor
- University of Mississippi Medical Center
Preterm, Sensory Disorder
Mother-to-infant Bonding and Prematurity Are Associated With Sensory Processing at 12 Months of Age
Establishing a strong bond between mother and infant is crucial for fostering healthy relationships in the future. This research sought to investigate the correlation between mother-to-infant bonding and sensory processing, as…
- Conditions
- Preterm, Sensory Disorder, Attachment Disorder
- Trial name
- NCT06232811
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gazi University
Respiratory Distress Syndrome in Premature Infants, Very Low Birth Weight Baby
Inhaled Nitric Oxide (iNO) as an Adjunct to Neonatal Resuscitation
This study hopes to determine whether nitric oxide along with oxygen during the first 20 minutes of life in infants needing help with breathing will reduce the percentage and total exposure to oxygen during that time frame.
- Trial name
- iNO (NCT01220687)
- Testing
- iNO, Nitrogen
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- University of Oklahoma
Premature Birth
Educational/Behavioral Intervention Program for Parents of Premature Infants
The purpose of this study is to determine whether beginning an enriched educational/behavioral program for parents of premature infants, very early in the Neonatal Intensive Care Unit (NICU) stay, and lasting until the child is 3…
- Trial name
- NCT00120614
- Testing
- Premature infant behavior and development information, Parental activities to support premature infant information
- Where
- 2 sites in United States
- Volunteers
- 260 people
- Sponsor
- University of Rochester
Preterm, Preterm Birth
Skincubator, a Novel Incubator for Skin to Skin Contact Feasibility Study
The goal of this clinical trial is to test the feasibility of using the Skincubator, a wearable incubator for skin to skin contact of preterm babies and their parents. It will also learn about the safety of skincubator.
- Trial name
- NCT06543433
- Testing
- Skincubator 2
- Where
- Australia
- Volunteers
- 50 people
- Sponsor
- Itamar Nitzan
Labor, Premature, Premature Birth
A Proof of Concept Study Assessing the Effect of Four Different Single Bolus Intravenous Doses of FE200440 and Placebo on Stopping Preterm Labor
To determine the effects of four different single bolus doses of FE200440 administered intravenously on stopping preterm labour compared to placebo in pregnant women with advanced gestational age
- Trial name
- NCT00209326
- Testing
- FE200440
- Where
- 17 sites in Belgium, Czechia and 4 more
- Volunteers
- 163 people
- Sponsor
- Ferring Pharmaceuticals
Infants in NICU Ventilated With HFV
Capnography in Infants Ventilated With High Frequency Ventilation
The investigators hypothesize that dEtCO2 measured by the Microstream® technique via a double-lumen ETT in infants ventilated with HFV would be feasible and adequately represent the arterial CO2 (PaCO2).
- Trial name
- NCT00859209
- Where
- Israel
- Volunteers
- 24 people
- Sponsor
- Bnai Zion Medical Center
Infant,Premature
Effects of Closed-loop Automatic Control of FiO2 in Extremely Preterm Infants
Extremely low gestational age neonates (ELGANs), i.e. those born at <28 weeks, frequently experience intermittent hypoxemic/hyperoxemic episodes.
- Trial name
- FiO2-C (NCT03168516)
- Testing
- closed-loop automatic control of the inspiratory fraction of oxygen (FiO2-C)
- Where
- 32 sites in China, Germany and 2 more
- Volunteers
- 1,065 people
- Sponsor
- University Hospital Tuebingen
Infant, Premature
Brain Volumes of Very Low Birth Weight Infants Measured by Cranial Ultrasonography
Neonatal cranial ultrasound (US) remains the method of choice to detect brain injury in high risk preterm infants on neonatal intensive care units (NICU).
- Trial name
- NCT02848755
- Testing
- Cranial ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 341 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Central Line Bloodstream Infections
The Effectiveness of Silver Alginate (Algidex) Patch in the Prevention of Central Line Infections in Very Low Birth Weight Infants
The purpose of this study is to determine whether silver alginate (Algidex) patch is effective in the prevention of central line infections in very low birth weight infants.
- Trial name
- NCT00964093
- Testing
- Silver Alginate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor Research Institute
Preterm Birth
Pessary as Adjunctive Therapy to Cerclage for the Prevention of Preterm Birth
Cervical cerclage was devised in the 1950's for women with prior early preterm births (PTB) who developed a dilated cervix detected by manual exam in the second trimester.
- Trial name
- NCT02678026
- Testing
- Cervical pessary
- Where
- Italy
- Sponsor
- Federico II University
Premature, Necrotizing Enterocolitis
Intestinal Perfusion After Feeding in Preterm and Term Infants
This is a pilot exploratory observational prospective cohort phase I study. In this study, we will gather preliminary data to evaluate (i) the magnitude of changes in blood flow in the bowel before and after feeding and (ii) the…
- Trial name
- NCT06319326
- Testing
- Evaluation of intestinal perfusion with color Doppler abdominal ultrasound before and after feeding.
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Preterm Birth
The Contribution of Internal Maternal Resources to Creation of Motherhood. Comparison Among Mothers to Twins and Singleton
Delivery of twins or preterm infant is a very stressful episode to mothers. The purpose of this study is to characterize maternal psychological resources in dealing with this situation and compare it to mothers giving birth to…
- Trial name
- NCT00353236
- Where
- Israel
- Sponsor
- Sheba Medical Center
Feeding Intolerance in Premature Infants
Glycerin Suppositories Used Prophylactically in Premature Infants (SUPP): a Pilot Randomized Placebo-controlled Trial
All premature babies have problems with feeding and nutrition. Some can develop a life-threatening bowel infection necrotizing enterocolitis.
- Trial name
- NCT02153606
- Testing
- Glycerin Suppository
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McMaster University