Clinical trials: Prevention of Cognitive Decline
Accidental Falls, Aging
Evaluation of the Effects of a Cognitive-Motor Fall Prevention Program on Fall Risk Factors
The goal of this interventional study is to compare in community dwelling elderly people the effects of two physical activity programs to prevent accident falls : "SILVER XIII EQUILIBRE" program and "VIVIFRAIL" program, on…
- Conditions
- Accidental Falls, Aging, Mild Cognitive Impairment
- Trial name
- 13EVAL (NCT05625828)
- Testing
- Cognitive-motor Physical Activity, Multifactorial Physical Activity
- Where
- France
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- EZUS-LYON 1
Cognitive Decline, Chemo-brain
Memantine for Prevention of Cognitive Decline in Patients With Breast Cancer
Purpose: To conduct a one-arm phase II trial to: (1) compare changes in pre- to post-chemotherapy cognitive function in a cohort of patients with breast cancer receiving memantine to historical controls; (2) examine how…
- Trial name
- NCT04033419
- Testing
- Memantine
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Mild Cognitive Impairment (MCI), Dementia
Integration of VR and AR Dementia Prevention Health Education Progrom for Older Adults With Mild Cognitive Impairment
The goal of this randomized controlled trial is to evaluate the effectiveness of Virtual Reality (VR)-based cognitive health education for older adults with mild cognitive impairment (MCI) in Taiwan.
- Conditions
- Mild Cognitive Impairment (MCI), Dementia, Health Literacy, Self-Efficacy
- Trial name
- NCT06888986
- Testing
- VR Dementia Prevention Health Education Module
- Where
- Taiwan
- Volunteers
- 139 people
- Sponsor
- National Taiwan Normal University
Horticultural Therapy, Dementia
Effects of Horticultural Therapy on Elderly at Risk of Cognitive Decline
The objective of this study is to determine whether horticultural therapy would improve the psychological well-being older adults who are at risk of memory (cognitive) decline.
- Trial name
- NCT03045718
- Testing
- Horticultural Therapy
- Where
- Singapore
- Volunteers
- 100 people
- Sponsor
- National University Hospital, Singapore
Prevention of Subclinical Atherosclerosis Progression, Prevention of Cognitive Decline
Nattokinase Atherothrombotic Prevention Study
The potential for nattokinase to "thin" blood and to reduce blood clotting by positive antithrombotic and fibrinolytic effects presents a unique opportunity to safely study such effects on cardiovascular disease and cognition.
- Trial name
- NAPS (NCT02080520)
- Testing
- Nattokinase
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Postoperative Cognitive Dysfunction
Effects of the Transcranial Stimulation on Prevention of Cognitive Dysfunction in Cardiac Surgery
Postoperative cognitive dysfunction (POCD) is a contrary event observed between 20 to 83%, especially on elderly and patients submitted to cardiac surgery.
- Trial name
- tDCS (NCT02549560)
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- University of Sao Paulo
Intermittent Fasting, Aging
The Effect of Intermittent Fasting on Brain Health
The central hypothesis of this study is that closer adherence to time restricted eating (TRE) will improve endothelial function, neurovascular (NVC) responses, resulting in improved cognitive performance, potentially through…
- Trial name
- NCT06019195
- Testing
- Time restricted eating
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Postoperative Cognitive Dysfunction, Postoperative Delirium
A Pilot Trial Evaluating the Effect of Tropisetron on Postoperative Cognitive Dysfunction After Cardiac Surgery
The purpose of this study is to assess the feasibility of a randomized, double-blind, placebo-controlled pilot trial evaluating the effect of tropisetron on prevention of postoperative cognitive dysfunction in patients after…
- Trial name
- NCT04195204
- Testing
- Tropisetron
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Beijing Chao Yang Hospital
Cognitive Dysfunction
Fluoxetine Prevention Trial
Many cancer survivors are experiencing problems with memory and other cognitive abilities following cancer treatment. Little is known concerning the contributions of potentially preventive therapies on cognitive function, but…
- Trial name
- NCT01615055
- Testing
- Fluoxetine
- Where
- 2 sites in United States
- Sponsor
- University of California, Los Angeles