Clinical trials: Prevention of Heart Disease
Atrial Fibrillation, Stroke
Systematic ECG Screening for Atrial Fibrillation Among 75 Year Old Subjects in the Region of Stockholm and Halland, Sweden
The purpose of this study is to determine whether screening for atrial fibrillation by intermittent ECG recording and initiation of anticoagulation treatment among high risk individuals is cost-effective and can lower the…
- Trial name
- NCT01593553
- Testing
- ECG screening for atrial fibrillation using intermittent ECG recorder
- Where
- Sweden
- Volunteers
- 7,173 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Myocardial Infarction, Stroke
Psychosocial Risk Factors in Stroke and Myocardial Infarction
The aim of this study is to identify groups of subjects at risk of recurrence in secondary prevention based on Psychosocial Factors.
- Trial name
- INEV@L (NCT02824107)
- Testing
- blood sample, questionnaires for psychosocial factors
- Where
- France
- Volunteers
- 294 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Acenocoumarol for the first…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947985
- Testing
- Rivaroxoban (Xarelto, Bay59-7939), Standard of care
- Where
- Netherlands
- Volunteers
- 208,958 people
- Sponsor
- Bayer
Acute Kidney Injury
Effect of Nitric Oxide in Cardiac Surgery Patients With Endothelial Dysfunction.
The purpose of this study is to determine whether nitric oxide is effective in the treatment of acute kidney injury in cardiac surgical patients with sign and laboratory data suggesting endothelial dysfunction undergoing…
- Trial name
- MGHK23 (NCT02836899)
- Testing
- Nitric Oxide
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Massachusetts General Hospital
Coronary Artery Disease
Topical Vancomycin in Prevention of Methicillin-Resistant Staphylococcal Related Mediastinitis in Patients Receiving Coronary Artery Bypass Graft
Sternal or mediastinal infections after heart operation occurs infrequently but carries a high cost in money, morbidity, and mortality.
- Trial name
- NCT00711685
- Testing
- coronary artery bypass grafting via midline sternotomy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Far Eastern Memorial Hospital
Atrial Fibrillation, Atrial Fibrillation (Prevention of Stroke)
Registry Initiative Across Borders for Atrial Fibrillation in Africa
Atrial fibrillation is a penalizing disease in several ways: morbidity and mortality, health costs. Several multicenter registries have been published.
- Conditions
- Atrial Fibrillation, Atrial Fibrillation (Prevention of Stroke), ATRIAL FIBRILLATION, Syncope
- Trial name
- RIBATAFRICA-AF (NCT06674304)
- Where
- Morocco
- Volunteers
- 3,000 people
- Sponsor
- Mohammed VI University Hospital
Kidney Failure, Acute
Effect of Erythropoietin (EPO) in Kidney After Cardiac Surgery
The purpose of this study is to determine whether erythropoietin is effective in preventing acute kidney dysfunction after coronary artery bypass grafting surgery.
- Trial name
- EPO-CABG (NCT00654992)
- Testing
- Erythropoietin-Beta, Normal Saline
- Where
- South Korea
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Atrial Fibrillation
Carvedilol for Prevention of Paroxysmal Atrial Fibrillation
Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is associated with significant symptoms and health problems including an increased risk of stroke and death.
- Trial name
- NCT01608893
- Testing
- Carvedilol, Metoprolol
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Schizophrenia, Cardiovascular Disease
Coronary Artery Disease in Patients Suffering From Schizophrenia
Schizophrenia is a severe mental illness associated with excess mortality and affecting nearly 1% of the population. The average life expectancy for patients diagnosed with schizophrenia has been 55-60 years through the last…
- Trial name
- NCT02885792
- Testing
- Illness history, Measure of social conditions, Measure of psychiatric condition
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Aalborg Psychiatric Hospital
Type 2 Diabetes Mellitus (T2DM), Atherosclerosis
Cilostazol and Aspirin for Cardiovascular Event Prevention in Patients With Type 2 Diabetes
Patients with type 2 diabetes and cardiovascular risk factors are at increased risk of cardiovascular events. Therefore, a multi-center prospective randomized study will be conducted to compare the efficacy and safety of…
- Trial name
- Cilo-Asa (NCT07719894)
- Testing
- Cilostazol, Aspirin
- Where
- South Korea
- Volunteers
- 1,200 people
- Sponsor
- Seoul National University Bundang Hospital
Respiratory Distress Syndrome, Adult, Ventricular Dysfunction, Right
The Value of Combined Critical Care Ultrasound and PAC Monitor Oriented Therapy Protocol to Patients of ARDS With ACP
We hypothesize that combined critical care ultrasound and PAC monitoring-oriented therapy protocol (CUP protocol), would improve prognosis of patients of ARDS with right ventricular dysfunction.
- Trial name
- NCT03971331
- Testing
- PAC catheter and critical care ultrasound examination
- Volunteers
- 236 people
- Sponsor
- Kang Yan
Coronary Atherosclerosis, Prevention of Heart Disease
CPR Training in 7th Grade Students
This is a prospective study of 7th grade students participating in the CPR Anytime® program. After consent, participants will be asked to complete the program with their parent(s)/legal guardian(s) and encouraged to include other…
- Trial name
- NCT00570609
- Testing
- CPR Anytime education
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Marna Rayl Greenberg
Deep Vein Thrombosis, Coronary Artery Bypass Surgery
A Study of the Efficacy of Preventive Dosing of Fondaparinux Sodium Versus Placebo for the Prevention of Venous Thromboembolism (VTE) in Patients Undergoing Coronary Bypass Surgery Receiving Routine Mechanical Prophylaxis
This trial is a prospective, single-center Phase II randomized study to demonstrate the superior efficacy of Fondaparinux Sodium subcutaneous injections in patients undergoing CABG surgery (isolated and redo isolated) versus…
- Conditions
- Deep Vein Thrombosis, Coronary Artery Bypass Surgery, Venous Thromboembolism
- Trial name
- NCT00789399
- Testing
- Fondaparinux
- Volunteers
- 78 people
- Sponsor
- Prairie Education and Research Cooperative
Atrial Fibrillation, Stroke
Prevention of Stroke by Left Atrial Appendage Closure in Atrial Fibrillation Patients After Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) in patients with non-valvular atrial fibrillation (NVAF) poses a particular dilemma for thromboprophylaxis.
- Conditions
- Atrial Fibrillation, Stroke, Intracerebral Hemorrhage
- Trial name
- NCT02830152
- Testing
- LAAO, Medical Therapy
- Where
- 17 sites in Denmark, Finland and 2 more
- Volunteers
- 750 people
- Sponsor
- Karolinska Institutet
Heart Block, CIED Related Infection
Biomarkers & Infection After Prophylactic Antibiotic in Cardiac Implantable Electronic Device Implantation
Effect of single dose \& intrapocket prophylactic antibiotic to cardiac implantable electronic device-related infection \& biomarkers
- Conditions
- Heart Block, CIED Related Infection, CIED-related Infections, Antibiotic Prophylaxis
- Trial name
- BI-PACED (NCT06448624)
- Testing
- Ampicillin sulbactam 3 days
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Diponegoro
Atrial Fibrillation, Risk Reduction
Prevention to Improve Outcomes After PVI
Atrial fibrillation (AF) is the most common cardiac arrhythmia and has a rising prevalence due to an aging population. AF increases the patient's risk of hospitalization, heart failure and stroke and results into deterioration of…
- Conditions
- Atrial Fibrillation, Risk Reduction, Nurse's Role
- Trial name
- POP (NCT05148338)
- Testing
- Comprehensive risk factor treatment, Standard of care
- Where
- Netherlands
- Volunteers
- 150 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Contrast-induced Nephropathy, Chronic Kidney Diseases
Multi-Center Trial Utilizing Low Frequency Ultrasound in the Prevention of Post-Contrast Acute Kidney Injury
Multi-center randomized trial to assess the safety and performance of low-frequency therapeutic ultrasound for maintaining renal function after contrast exposure.
- Trial name
- LOTUS (NCT04877847)
- Testing
- Low-frequency therapeutic ultrasound (LOTUS), LOTUS System with Ultrasound Disabled
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Sonogenix
Cardiovascular Diseases, Coronary Disease
Effects of CHD Prevention on Lipoprotein Subclasses
To assess the influence of HDL-subclasses with coronary disease progression, and to identify factors influencing HDL subclasses at baseline and over time.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00005426
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Atrial Fibrillation
Homeopathy for Prevention of Atrial Fibrillation After Aortocoronary Bypass Surgery
After heart surgery, about 30% of patients suffer from atrial fibrillation. Patients are randomized into two groups receiving either potentized Strychnos Nux vomica or placebo under double blind conditions.
- Trial name
- NCT00861237
- Testing
- Nux vomica (active comparator)
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- Medical University of Vienna
Postoperative Period, Physical Therapy Modalities
Positive Pressure Therapy to Optimize LUNG Function After Heart Surgery
The most common cardiac surgeries are myocardial revascularization and valve replacement or plastic surgery. In the postoperative period of cardiac surgeries, the incidence of pulmonary complications ranges from 30% to 50% and is…
- Conditions
- Postoperative Period, Physical Therapy Modalities, Continuous Positive Airway Pressure, Respiratory Function Tests
- Trial name
- PRO-LUNGHS (NCT06611527)
- Testing
- PS+PEEP group, CPAP group
- Where
- Brazil
- Volunteers
- 156 people
- Sponsor
- Federal University of São Paulo