Clinical trials: Preventive Intervention
Clinical Trial
AFRI Childhood Obesity Prevention Challenge Area
This study is a hybrid type 2 effectiveness-implementation trial of the Family Check-Up 4 Health (FCU4Health), an adapted version of the Family Check-Up, in pediatric primary care.
- Trial name
- NCT04469816
- Testing
- Family Check-Up 4 Health, Services as Usual
- Where
- 4 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Anemia, Folate Deficiency
Quadruple Fortified Salt Trial in India
Women of reproductive age are at an increased risk of anemia and micronutrient deficiencies. Evidence supports the role of periconceptional nutrition in the development of neural tube defects and other pregnancy complications.
- Conditions
- Anemia, Folate Deficiency, Vitamin B 12 Deficiency
- Trial name
- QFS (NCT03853304)
- Testing
- + Folic acid, + Vitamin B12, DFS
- Where
- India
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Cornell University
Tobacco Dependence
Effects of Yoga and Cardiovascular Exercise on Smoking Motivation
The overall purpose of this pilot study is to examine effects of Hatha yoga and cardiovascular exercise on craving, mood, cue reactivity, and smoking behavior.
- Trial name
- NCT01423578
- Testing
- Hatha Yoga (HY), Cardiovascular Exercise (CE), Smoking Cessation Counseling
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Gestational Diabetes Mellitus in Pregnancy
D-chiro Inositol in Prevention of Gestational Diabetes Mellitus in China
Inositol is a type of food additives, which plays an important role in insulin signal pathway and is related to insulin sensitivity.
- Trial name
- NCT04801485
- Testing
- D-chiro inositol
- Where
- China
- Volunteers
- 291 people
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Migraine
DP-VPA for Migraine Prophylaxis, a Pilot Efficacy Study
The study will evaluate if DP-VPA, a derivative of valproate (a drug that is commonly used for the prevention of migraine attacks), can reduce the rate of migraine attacks.
- Trial name
- NCT00640965
- Testing
- DP-VPA
- Where
- 6 sites in Israel
- Volunteers
- 40 people
- Sponsor
- D-Pharm Ltd.
Surgical Wound Infections
Prevention of Neurosurgical Wound Infections
The goal of this study is to determine whether injecting the antibiotic vancomycin directly into surgical wounds can decrease the rate of infection following implantation of neurosurgical devices.
- Trial name
- POWI (NCT00915967)
- Testing
- Vancomycin
- Where
- United States
- Volunteers
- 214 people
- Sponsor
- Oregon Health and Science University
HIV, Violence, Gender-Based
Development and Evaluation of a PrEP Decision Aid for Women Seeking Domestic Violence Services in Baltimore
This study is designed to develop and test an individual decision aid for pre-exposure prophylaxis (PrEP) tailored to Black women who have been exposed to intimate partner violence and are working with a domestic violence service…
- Conditions
- HIV, Violence, Gender-Based, Pre-Exposure Prophylaxis
- Trial name
- NCT05614492
- Testing
- Individual PrEP Decision Aid, CDC PrEP Video, Shared PrEP Decision Aid
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Atrial Fibrillation (AF), OPCABG
Transcutaneous Regulation for Atrial Prevention in Postoperative Atrial Fibrillation Following OPCAB
Postoperative atrial fibrillation (POAF) is a common complication after coronary artery bypass surgery and may be associated with prolonged hospitalization and adverse cardiovascular outcomes.
- Trial name
- TRAP-AF (NCT07824492)
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation
- Volunteers
- 410 people
- Sponsor
- Ruijin Hospital
Suicide, Suicide, Attempted
A Brief Intervention to Reduce Suicide Risk in Military Service Members and Veterans - Study 2 (SAFEMIL)
The investigators propose to test the efficacy of a brief, readily accessible, and personalized treatment called the Safety Planning for Military (SAFE MIL; Stanley and Brown, 2012).
- Trial name
- SAFEMIL (NCT01360736)
- Testing
- Safety Planning - Military (SAFE MIL)
- Where
- 2 sites in United States
- Volunteers
- 102 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Suicidal Ideation and Behavior
Stepped-Care for Suicidal Youth and Children
The goal of this RCT study is to test the efficacy of a stratified stepped-care (SSC) model in reducing suicidal thoughts and behaviors (STB) in children and adolescents. The main questions it aims to answer are: 1.
- Trial name
- SURE-CARE (NCT07321171)
- Testing
- IPC-A-SCI (Interpersonal Counseling for Suicide Crisis Intervention), IPT-A-SCI (Interpersonal Psychotherapy for Adolescents with Suicidal Crisis Intervention)
- Where
- Israel
- Volunteers
- 350 people
- Sponsor
- Shira Barzilay
Uremia; Chronic, Cardiovascular Diseases (CVD)
Prevention and Management of Cardiovascular and Cerebrovascular Complications in Maintenance Hemodialysis (MHD) Patients
Background and Purpose: This clinical study aims to explore and validate two innovative treatment strategies to address two major challenges faced by patients on maintenance hemodialysis (uremia): the high incidence of…
- Conditions
- Uremia; Chronic, Cardiovascular Diseases (CVD), Cerebrovascular Disorders, Intradialytic Hypotension
- Trial name
- NCT07335471
- Testing
- Continuous High-Glucose Infusion and Regular Hemoperfusion in Maintenance Hemodialysis
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Suzhou Municipal Hospital of Anhui Province
Adenovirus Disease
Phase 2 Study to Evaluate Brincidofovir for the Prevention of Adenovirus Disease
This study was designed to assess the safety and efficacy of preemptive treatment with oral brincidofovir (BCV), as compared to placebo, for the prevention of adenovirus (AdV) disease in recipients of hematopoietic stem cell…
- Trial name
- NCT01241344
- Testing
- Brincidofovir
- Where
- 30 sites in United States
- Volunteers
- 52 people
- Sponsor
- Jazz Pharmaceuticals
Spinal Fusion, Nausea and Vomiting, Postoperative
Aprepitant Treatment to Prevent Postoperative Nausea and Vomiting in Children Undergoing Scoliosis Surgery
This research trial will measure how useful Aprepitant is in preventing nausea and vomiting in children having surgery to correct scoliosis (curvature of the spine).
- Conditions
- Spinal Fusion, Nausea and Vomiting, Postoperative, Anesthesia
- Trial name
- NCT06357234
- Testing
- Aprepitant
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- IWK Health Centre
the Effect of Hypotension Prediction Index Application
Hypotension Prediction Index in Major Gastrointestinal Surgery
Intraoperative hypotension (IOH) is defined as a mean arterial pressure (MAP) of < 65mmHg during surgery. Patients undergoing major gastrointestinal (GI) surgery, such as esophagectomy with reconstruction, are at a high-risk of…
- Trial name
- NCT04966364
- Testing
- hypotension prediction index guided, without hypotesion prediction index guided
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Type 2 Diabetes Mellitus
Preventive Effectiveness of Primary Care Physician-led CGM-supported Comprehensive Intervention on Cardio-metabolic-immune Diseases in Community Patients With Type 2 Diabetes (Community Diabetes Control Project)
This community-based trial evaluates whether primary care physicians, equipped with continuous glucose monitoring (CGM) and trained under a standardized protocol with specialist backup, can improve diabetes outcomes through…
- Trial name
- CDCP (NCT07885904)
- Testing
- comprehensive intervention
- Where
- China
- Volunteers
- 15,400 people
- Sponsor
- Xiangya Hospital of Central South University
Post Traumatic Stress Disorder
Early Prevention of Post Traumatic Stress Disorder
Sunnybrook Health Sciences Centre is Canada's largest trauma centre, treating 1,100 patients annually. A traumatic experience can lead to post-traumatic stress disorder, which increases hospital stays, emergency visits and…
- Trial name
- NCT02004743
- Testing
- Intervention, Treatment as usual
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- Sunnybrook Health Sciences Centre
Chemotherapy-induced Neutropenia, Myelosuppression
Real World Study of PEG-rhG-CSF in Prevention of Chemotherapy-induced Neutropenia
The aim of this study is to observe and evaluate the cost-effectiveness,efficacy and safety of PEG-rhG-CSF in preventing chemotherapy-induced neutropenia(CIN) of cancer patients in the real world.1000 patients with non-myeloid…
- Trial name
- NCT03846414
- Testing
- PEG-rhG-CSF
- Volunteers
- 1,500 people
- Sponsor
- CSPC Baike (Shandong) Biopharmaceutical Co., Ltd.
Hamstring Injuries
Prevention of Hamstring Injuries in Football Players.
Introduction: The prevalence of hamstring injuries in football is high, causing an increase in the number of casualties and a high socio-economic cost.
- Trial name
- NCT05773404
- Testing
- Passive Neurodynamics and Passive axial hip mobilisation/distraction, Active therapy, 2.5.3. Combined therapy
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Universidad Católica de Ávila
Myopia
The Use of Atropine 0.01% in the Prevention and Control of Myopia (ATOM3)
Study of low dose atropine in preventing the onset and progression of myopia in high risk children with pre-myopia or low-myopia.
- Trial name
- NCT03140358
- Testing
- Atropine sulfate 0.01%
- Where
- Singapore
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
HIV-infection/Aids
Community-Based Peer Facilitator Intervention (Zimbabwe)
The goal of this community randomized operations research study was to evaluate the effect of a peer-facilitated community support group intervention on uptake of maternal and neonatal child health (MNCH) and PMTCT services and…
- Trial name
- NCT02496793
- Testing
- Peer-facilitated community support group
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
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