Clinical trials: Preventive Intervention
Uterine Atony, Post-partum Hemorrhage
Comparison of Two Doses of Carbetocin for Prevention of Uterine Atony, During Elective Cesarean Section
The purpose of this study is to evaluate the effectiveness of two doses of carbetocin (50 mcg vs 100 mcg) in preventing uterine atony during elective cesarean section.
- Trial name
- NCT01630187
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 72 people
- Sponsor
- Laval University
Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma (HNSCC)
Effects of Avmacol® in the Oral Mucosa of Patients Following Curative Treatment for Tobacco-related Head and Neck Cancer
Avmacol is an over-the-counter dietary supplement containing broccoli seed and sprout extracts in tablet form, hypothesized to activate protective cellular pathways including detoxication.
- Conditions
- Head and Neck Cancer, Head and Neck Squamous Cell Carcinoma (HNSCC), Head and Neck Carcinoma, Head and Neck
- Trial name
- NCT03268993
- Testing
- Avmacol
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Pittsburgh
Parent-child Interaction
Beginning Relationships in a Native Community
The purpose of this study is to to conduct a randomized controlled trial comparing an intervention group and a control/wait list group to evaluate the feasibility of the Promoting First Relationships method in an American Indian…
- Trial name
- P20-RP3 (NCT02091804)
- Testing
- Immediate Group, Wait-List group
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Washington
COVID-19, Venous Thromboembolism
Clinical Trial of Dimolegin (DD217) in Prevention of Thrombotic Complications in Patients With COVID-19
Study purpose was to study the safety and efficacy of Dimolegin - DD217 as a drug for prevention of thrombotic complications compared to Clexane (enoxaparin sodium) - the standard therapy currently prescribed to patients…
- Trial name
- NCT05185804
- Testing
- Dimolegin, Clexane
- Where
- 6 sites in Russia
- Volunteers
- 399 people
- Sponsor
- PharmaDiall Ltd.
Surgical Site Infection
PRevention Of Trauma-related Infections Through an Embedded Clinical Trials Network
The purpose of this study is to compare the effectiveness of 2 prophylactic antibiotic regimens, ertapenem and cefazolin with metronidazole, in preventing organ space surgical site infections (OS-SSI) after emergency trauma…
- Trial name
- PROTECT (NCT06920147)
- Testing
- Ertapenem, Cefazolin and Metronidazole.
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The University of Texas Health Science Center, Houston
Asthma
CARE - Quality Improvement in Asthma Secondary Prevention in Primary Care, Through Delegation of Consultations to the Nurse.
Quality Improvement in Primary Care: delegation of check-ups to nurses in general practice
- Trial name
- NCT00714038
- Where
- 93 sites in Denmark
- Volunteers
- 2,122 people
- Sponsor
- AstraZeneca
Stroke
SINEMA Model of Care to Improve the Health of Stroke Patients in Rural China
Despite the significant burden of stroke in rural China, secondary prevention of stroke is scarce. The aim of the study is to develop a system-integrated technology-enabled intervention (SINEMA) model for the secondary prevention…
- Trial name
- SINEMA (NCT03185858)
- Testing
- SINEMA intervention
- Where
- China
- Volunteers
- 1,299 people
- Sponsor
- Duke Kunshan University
Sedentary Behavior, Aging
Social Marketing in Prevention Actions
Physical Activity (PA) is recognized as the most effective method to prevent falls in the elderly. Yet despite there being a consensus now that Physical Activity (PA) is effective in practice, there remain many obstacles to…
- Trial name
- NCT04136938
- Testing
- Social marketing campaign
- Where
- France
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Demineralization, Tooth, Caries,Dental
Prospective Randomized Controlled Trial for Prevention of Demineralization During Fixed Orthodontic Treatment
Treatment with fixed orthodontic appliances is often associated with pain, which poses great challenges in the efficient brushing of the teeth thus making the teeth more vulnerable to plaque formation.
- Conditions
- Demineralization, Tooth, Caries,Dental, White Spot Lesion
- Trial name
- NCT04342858
- Testing
- Fluoride Varnish, Fluoride Varnish with tricalcium phosphate, Oral health education
- Where
- Hong Kong
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Child Obesity
Mixed Methods Feasibility Study of an App for Childhood Obesity Prevention and Management
This evaluation evaluated Health Education England's NoObesity digital health app's usability and acceptability to undertake activities improving families' diet, physical activity and weight.
- Trial name
- NCT05261555
- Testing
- NoObesity app
- Where
- United Kingdom
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- University of Plymouth
Smoking Cessation, Weight Loss
Behavioral Activation for Smoking Cessation and the Prevention of Post-Cessation Weight Gain
The purpose of this research study is to better understand (1) why people gain weight when they quit smoking and (2) whether certain types of smoking cessation (i.e.
- Trial name
- NCT02906787
- Testing
- BAS+, SC
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Cardiovascular Diseases, Heart Diseases
Prevention of Recurrent Venous Thromboembolism (PREVENT)
A multicenter randomized, double blind placebo controlled trial to determine the efficacy of long-term, low dose warfarin in the secondary prevention of venous thromboembolism.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Peripheral Vascular Diseases, Thromboembolism
- Trial name
- NCT00000614
- Testing
- warfarin
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection
Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery
Our Aim is to identify patient risk factors and clinical practices associated with healthcare-acquired infections (HAIs) after cardiac surgery.
- Conditions
- Healthcare Associated Infectious Disease, Sternal Superficial Wound Infection, Sepsis, Pneumonia
- Trial name
- HAI (NCT02068716)
- Where
- United States
- Volunteers
- 911,754 people
- Sponsor
- Dr. Donald Likosky
Type2 Diabetes, Covid19
Advancing DSME/S and COVID-19 Prevention and Protection Through "emPOWERed to Change" Program
African Americans (AA)/People of Color (POC) are disproportionately impacted by COVID-19 to an extent not observed in other racial/ethnic subgroups.
- Trial name
- NCT04993326
- Testing
- emPOWERed To Change Program
- Sponsor
- Charles Drew University of Medicine and Science
Prescription With Medication Errors
The General Objective of This Study is to Monitor, Assess, and Prevent the Potential Medication Errors Among Inpatients in the Tertiary Healthcare Facility of Nepal. This Study Aims to Develop and Implement the Medication Errors Reporting System in Hospital Settings.
The goal of this observational study is to develop and implement Medication errors reporting system using the error reporting guidelines.
- Trial name
- NCT07002606
- Testing
- medication errors reporting guidelines
- Volunteers
- 62 people
- Sponsor
- Kathmandu University School of Medical Sciences
Child Sexual Abuse
Safe Touches: A Rigorous Evaluation of a Sexual Abuse Prevention Program for Children
The primary goal of the study is to conduct a rigorous evaluation of the sexual abuse prevention program entitled, "Safe Touches: Personal Safety Training for Children (Safe Touches)." The main study hypothesis is that children…
- Trial name
- Safe Touches (NCT02181647)
- Testing
- Safe Touches: Personal Safety Training for Children
- Where
- United States
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- The New York Society for the Prevention of Cruelty to Children
Anxiety, Depression
Research of Prevention and Intervention of Mental Health Problems
The purpose of this research is to establish a suitable community-based model for Chinese culture,to improve the community recognition of common mental disorders,as well as its treatment and control.
- Conditions
- Anxiety, Depression, Alcohol-abuse
- Trial name
- RPIMHP (NCT01422447)
- Testing
- regular intervention, community intervention
- Where
- 7 sites in China
- Volunteers
- 42,016 people
- Sponsor
- Shanghai Mental Health Center
Aortic Aneurysm, Abdominal
Exercise Therapy to Treat Adults With Abdominal Aortic Aneurysms
An abdominal aortic aneurysm (AAA) is a weakened and enlarged area in the abdominal aorta, which is a large blood vessel in the abdomen. If an AAA ruptures, it can be life-threatening.
- Trial name
- AAA:STOP (NCT00349947)
- Testing
- Exercise Program
- Where
- 3 sites in United States
- Volunteers
- 2,400 people
- Sponsor
- Stanford University
Oral Cancer, Oral Leukoplakia
Oral Cancer Screening and Education in Hong Kong
This study will be conducted to obtain data on oral cancer risk factors to generate machine learning models with good predictive accuracy for stratifying individuals with high-oral cancer risk and delineating high-risk and…
- Conditions
- Oral Cancer, Oral Leukoplakia, Oral Submucous Fibrosis, Proliferative Verrucous Leukoplakia
- Trial name
- NCT04487938
- Testing
- No intervention utilised
- Volunteers
- 3,190 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Suicide, Suicide Attempt
Suicidal Ideation Framework: Grounded Theory Study, Catalonia
This doctoral project aims to develop a comprehensive theoretical model of the process through which the suicidal ideation framework is configured as a symbolic, narrative, and relational expression, adopting a multiperspective…
- Conditions
- Suicide, Suicide Attempt, Suicide Ideation, Suicide Risk
- Trial name
- SUIF-GT-CAT (NCT07284238)
- Testing
- In-Depth Qualitative Interview, Discussion Group
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
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