Clinical trials: Preventive Medicine
School Adaptation, School Readiness
Scientific Justification of Assessment Criteria and Improvement of the Methodology for Assessing School Maturity
One of the critical stages in a child's life is the beginning of school, accompanied by intense intellectual and psycho-emotional stress.
- Trial name
- NCT05736159
- Testing
- Method of assessment of school maturity, Assessment of school adaptation
- Where
- Russia
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Samara State Medical University
Medication Adherence
Perspectives on Prophylactic Antibiotic Use in Dermatologic Surgery
This is a prospective, multi-center observational survey study to uncover how antibiotic differences can influence utilization decisions.
- Trial name
- NCT04150523
- Testing
- Survey
- Where
- 8 sites in United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
BRCA1 Mutation, Breast Cancer
Studying the Effect of Denosumab on Preventing Breast Cancer in Women With a BRCA1 Germline Mutation
This phase III trial compares denosumab to placebo for the prevention of breast cancer in women with a BRCA1 germline mutation. A germline mutation is an inherited gene change which, in the BRCA1 gene, is associated with an…
- Conditions
- BRCA1 Mutation, Breast Cancer, Breast Diseases, Breast Neoplasms
- Trial name
- BRCA-P (NCT04711109)
- Testing
- Denosumab, Quality-of-Life Assessment
- Where
- 47 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Alliance for Clinical Trials in Oncology
Heart Attack
The Role of Genetic Factors in the Development of Myocardial Infarction in the Kazakh Population
This is a GWAS study that aims to identify possible candidate genes associate to heart attack by exploring single nucleotide polymorphism (SNP) in a group of heart attack, in the Kazakh population.
- Trial name
- NCT05090618
- Testing
- DNA analysis
- Where
- Kazakhstan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Asfendiyarov Kazakh National Medical University
Human Papillomavirus (HPV) Infection, HPV Vaccination Acceptance/Intention
Effect of Different HPV Education Methods on Vaccination Intention in Young Women
Detailed Description Human papillomavirus (HPV) is one of the leading causes of cervical cancer and can be prevented by vaccination.
- Trial name
- NCT07420556
- Testing
- Video-Based HPV Education, Face-to-Face HPV Education
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Emel GÜÇLÜ CİHAN
Patients With Malignant Blood Disease Requiring Hepatitis B Antiviral Medication
Clinical Trial for Non-inferiority and Safety of Tenofovir Alafenamide and Tenofovir Disoproxil Fumarate in Patients With Hematologic Malignancies Who Require Prophylactic Hepatitis B Antiviral Treatment
his clinical trial was conducted to determine the non-inferiority and safety of prophylactic antiviral treatment of Tenofovir alafenamide (TAF) compared to Tenofovir disoproxil fumarate (TDF) in patients with malignant…
- Trial name
- NCT06221657
- Testing
- Vemlidy, Virreal
- Volunteers
- 100 people
- Sponsor
- Yonsei University
Preventative Medicine
The Effectiveness of Mental Health First Aid Intervention Among Undergraduate Students in Switzerland
Mental Health First Aid (MHFA) is an educational training program which has been proven effective at increasing knowledge, improving attitudes and reducing the stigma of mental illness among individuals/the general population.
- Trial name
- NCT06035770
- Testing
- Mental Health First Aid (educational training program)
- Where
- Switzerland
- Volunteers
- 107 people
- Sponsor
- Institut et Haute Ecole de la Santé la Source
Sexual Risk Behavior, Drug Use
eHealth Evidence-based Intervention (EBI) for Latino Youth in Primary Care
The purpose of this study is to test the relative effectiveness of a Hispanic-specific eHealth intervention, "e-Health Familias Unidas," in preventing and reducing drug use, sexual risk behaviors, and STIs among Hispanic youth in…
- Conditions
- Sexual Risk Behavior, Drug Use, Family Functioning
- Trial name
- NCT03009539
- Testing
- eHealth Familias Unidas Primary Care
- Where
- 12 sites in United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- University of Miami
Corona Virus Infection
Ozone Therapy in the Prevention of COVID-19 Infection
Coronavirus has already infected 4,673,809 people and killed 312,646 people worldwide, and no specific treatment or a vaccine against it has yet proven to be effective.
- Trial name
- NCT04400006
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people
- Sponsor
- Marmara University
Cancer
Promoting Organizational Capacity to Implement Cancer Control Programs Among Latino Churches
This research study aims to develop an organizational-level intervention to enable communities to adopt, adapt, implement and sustain evidence-based interventions (EBIs) to address cancer disparities among Latinos.
- Trial name
- CRUZA (NCT01740219)
- Testing
- Capacity Enhancement, Standard Dissemination
- Where
- 3 sites in United States
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Dana-Farber Cancer Institute
Systemic Lupus Erythematosus (SLE)
CCCR Lupus Patient Navigator Program
To address the health disparities in SLE outcomes for minorities, targeted intervention will be used to address the common barriers to care among patients; a comprehensive patient navigator approach will be utilized based on…
- Trial name
- NCT04461158
- Testing
- Patient Navigator Services
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Medical University of South Carolina
Adverse Effects, Ascorbic Acid
Systemic Adverse Effects After Osteopathic Treatment and Vitamin C
The goal of this triple-blind randomized clinical trial is to learn about systemic adverse effects in first visit patients who attend an osteopathic medicine center in Barcelona.
- Conditions
- Adverse Effects, Ascorbic Acid, Oxidative Stress
- Trial name
- NCT06102577
- Testing
- 1gr. Vitamine C, control group
- Where
- Spain
- Volunteers
- 99 people
- Sponsor
- Centre Medicina Esportiva i Osteopatia, Spain
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Clinical Effect of Preventive Use of Tylenol on Fever After Removal of Drainage Tube in Lumbar Fusion Surgery
This study evaluates the influence of Non-steroidal Anti-inflammatory Drugs on preventing fever after the removal of drainage tube in the patients who suffered lumbar fusion surgery, if the outcome turn out positive, the…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Radiculopathy
- Trial name
- NCT04042948
- Testing
- Tylenol
- Where
- China
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Mycobacterium Avium-intracellulare Infection, HIV Infections
Effects of MAC Preventive Therapy on Disease-Causing Bacteria in HIV-Infected Patients: A Substudy of CPCRA 048
Some people who have taken azithromycin to prevent MAC (Mycobacterium avium Complex, a bacterial infection common in HIV-infected persons) have been found to carry antibiotic-resistant bacteria (germs that grow despite the…
- Conditions
- Mycobacterium Avium-intracellulare Infection, HIV Infections, Pneumococcal Infections
- Trial name
- NCT00000933
- Where
- 15 sites in United States
- Volunteers
- 326 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Primary Prevention, Healthy Aging
Personalized Disease Prevention
This study will evaluate whether patients and their providers benefit from an evidence-based decision tool to help prioritize preventive (and select chronic disease management) services based on their potential to improve…
- Conditions
- Primary Prevention, Healthy Aging, Quality of Life, Decision Support Techniques
- Trial name
- PDP (NCT05463887)
- Testing
- Individualized preventive care recommendations (decision tool)
- Where
- United States
- Volunteers
- 721 people, healthy volunteers welcome
- Sponsor
- Glen Taksler
Preventive Medicine
Preventing Chronicity of Sub-acute Low Back Pain by Altering the Neural Emotional Response to Pain
Aim of the study It could be stated that chronification of low back pain in some respects depends on the emotional reactions to the acute pain state.
- Trial name
- NCT05450263
- Testing
- Interoceptive exposure
- Where
- Finland
- Sponsor
- Orton Orthopaedic Hospital
Malaria,Falciparum, Anemia
Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzania
Background: In high-transmission settings, up to 70% of school-aged children harbour malaria parasites which is mostly asymptomatic, thus, from an epidemiological point of view, they contribute significantly as reservoir to…
- Trial name
- InSMART-school (NCT03640403)
- Testing
- Dihydroartemisinin-piperaquine, Artesunate-amodiaquine
- Where
- Tanzania
- Volunteers
- 1,555 people, healthy volunteers welcome
- Sponsor
- National Institute for Medical Research, Tanzania
Malaria
Kilimanjaro IPTi Drug Options Trial
Malaria and anaemia are major causes of morbidity and mortality in children in sub-Saharan Africa. Administration of three courses of sulfadoxine/pyrimethamine (SP) as intermittent preventive treatment (IPTi) to infants when they…
- Trial name
- NCT00158574
- Testing
- sulphadoxine-pyrimethamine, mefloquine, Chlorproguanil-dapsone
- Where
- Tanzania
- Volunteers
- 2,419 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Assessing the Bleeding Profile and the Quality of Life of the Enrolled Patients Before and 1 Year After Drug Intervention
Use of Recombinant Factor VII as a Prophylactic Therapy for Adolescent Females With Heavy Menstrual Bleeding
the study is conducted on adolescent females proved to be Glanzmanns Thrombaesthenia with heavy menstrual bleeding by the use of 3 doses of recombinant factor VII in the first day of their cycles.
- Trial name
- NCT06258980
- Testing
- Proph7
- Where
- Egypt
- Volunteers
- 3 people
- Sponsor
- Minia University Hospital
Lupus Erythematosus, Systemic
Prophylactic Trimethoprim/Sulfamethoxazole to Prevent Severe Infections in Patients With Lupus Erythematous
The purpose of this study is to determine whether trimethoprim/sulfamethoxazole is effective in preventing serious infectious complications (those that require hospitalization or lead to death) in patients with lupus…
- Trial name
- NCT03042260
- Testing
- Trimethoprim-Sulfamethoxazole
- Where
- Mexico
- Volunteers
- 310 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran