Clinical trials: Primary
Tension-type Headache
Muscle Soreness and Stiffness in Patients With Chronic or Frequent Episodic Tension Type Headache.
The aim is to investigate muscle soreness and stiffness in patients with Chronic or Frequent Episodic Tension Type Headache before and after treatment with amitriptyline - and to compare the results with healthy individuals.
- Trial name
- NCT02746250
- Testing
- Amitriptyline
- Where
- Denmark
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Endometrial Cancer
Combination Chemotherapy With or Without G-CSF in Treating Patients With Stage III, Stage IV, or Recurrent Endometrial Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00003691
- Testing
- filgrastim, cisplatin, doxorubicin hydrochloride
- Where
- 73 sites in United States, Canada
- Volunteers
- 240 people
- Sponsor
- Gynecologic Oncology Group
Pain, Chronic
Mobile-Based Contingency Management to Promote Daily Self-monitoring in Primary Care Patients
This project examines the efficacy and feasibility of contingency management (CM), delivered using a novel, fully automated CM app (DynamiCare Rewards), to promote daily self-monitoring of pain symptom severity and related…
- Trial name
- ProMPT (NCT03962491)
- Testing
- Daily Self-Monitoring Surveys + Contingency Management, Daily Self-Monitoring Surveys
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Virginia Commonwealth University
Alcohol Consumption
Impact of Alcohol Consumption on Use of Health Care Resources
The prevalence of alcohol-related disorders in the general population is around 10%. The relationship between the use of healthcare services, costs and the amount of alcohol consumed by the general population is unknown.
- Trial name
- NCT02343874
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 1,911,771 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
HIV, Rabies
Immune Response After Booster Vaccination in HIV - Infected Patients Who Received Rabies Primary Vaccination
Booster rabies vaccination in HIV - infected patients who have ever received rabies primary vaccination could improve their immune response to this kind of vaccine.
- Trial name
- NCT01286493
- Testing
- rabies vaccines on day 0 and 3
- Where
- Thailand
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Queen Saovabha Memorial Institute
Pediatric Obesity, Overnutrition, Child
IMplementation of the Family Support PRogramme A Healthy School Start to Prevent OVErweight and Obesity (IMPROVE)
IMPROVE is an implementation study aiming to explore the effects of two bundled implementation strategies on the intervention fidelity of the Healthy School Start program (primary outcome) while simultaneously monitoring effects…
- Conditions
- Pediatric Obesity, Overnutrition, Child, Prediabetic State, Diabetes Mellitus, Type 2
- Trial name
- IMPROVE (NCT04984421)
- Testing
- Healthy School Start
- Where
- 3 sites in Sweden
- Volunteers
- 1,634 people
- Sponsor
- Karolinska Institutet
Migraine, Tension-Type Headache
German Translation and Cross-cultural Adaptation of the Headache Screening Questionnaire (HSQ) Followed by a Test-retest Reliability Study.
The goal of this study is to learn more about the Headache Screening Questionnaire in people with Headache. The main question is: Does the lower limit of a 95% confidence interval of the HSQ in physiotherapy during a period of 2…
- Trial name
- GUR-HSQ (NCT05893004)
- Testing
- Headache Screening Questionnaire
- Where
- Switzerland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Markus J. Ernst
Chronic Kidney Diseases, Type 2 Diabetes Mellitus
Prevalence, Incidence and Risk Signature of Chronic Kidney Disease in Sub-Saharan Africa
Chronic kidney disease (CKD) is associated with increased cardiovascular morbidity and mortality. The prevalence of CKD is increasing worldwide and is assumed to also dramatically increase in Sub-Saharan Africa (SSA).
- Conditions
- Chronic Kidney Diseases, Type 2 Diabetes Mellitus, Arterial Hypertension, Obesity
- Trial name
- RenalTWO (NCT05881447)
- Where
- Tanzania
- Volunteers
- 1,200 people
- Sponsor
- Swiss Tropical & Public Health Institute
Migraine
A Study to Learn About the Safety and Effects of Rimegepant to Prevent Migraine in Chinese Subjects.
The purpose of this study is to learn about the effects of Rimegepant to help prevent migraine. This study is seeking for participants who: Are male and female of 18 years of age or older.
- Trial name
- NCT05810038
- Testing
- Rimegepant
- Where
- 49 sites in China
- Volunteers
- 787 people
- Sponsor
- Pfizer
Lymphedema of Upper Limb
The Relationship Between Primary Lymphedema and Joint Hypermobility
Lymphoedema is the swelling of one or several parts of the body owing to lymph accumulation in the extracellular space. It is often chronic, worsens if untreated, predisposes to infections and causes an important reduction in…
- Trial name
- NCT06399458
- Testing
- For hypermobility; Beighton score and Brighton revised 1998 Criteria
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Primary Sjögren Syndrome
A Study of RSLV-132 in Females With Sjögren's Disease
The goal of this clinical study is to learn if RSLV-132 improves the symptoms of SS in adults. It will also learn about the safety of RSLV-132.
- Trial name
- NCT06440525
- Testing
- RSLV-132
- Where
- 24 sites in United States
- Volunteers
- 106 people
- Sponsor
- Resolve Therapeutics
Liver Abscess
Moxifloxacin Versus Ceftriaxone in the Treatment of Primary Pyogenic Liver Abscess
This clinical trial compares the use of moxifloxacin versus ceftriaxone in the treatment of primary pyogenic liver abscess. The trial will include nonpregnant adults presenting with primary liver abscess based on clinical…
- Trial name
- NCT00895089
- Testing
- Moxifloxacin (Avelox), ceftriaxone
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Open Angle Glaucoma, Primary Open Angle Glaucoma
IOP and Medication Reduction in MIGS Procedures
The primary objective of this research is to compare the efficacy of trabecular minimally invasive glaucoma surgery (MIGS) devices (iStent vs iStent Inject vs Hydrus) for intra ocular pressure (IOP) and anti-glaucoma medication…
- Conditions
- Open Angle Glaucoma, Primary Open Angle Glaucoma, Pigmentary Glaucoma, Pseudoexfoliation Glaucoma in Both Eyes
- Trial name
- NCT04202510
- Testing
- Glaucoma and Cataract Surgery
- Where
- United States
- Sponsor
- Wills Eye
Primary Immunodeficiency Disease
IVIG Boya: Safety, Efficacy, and Pharmacokinetics
The goal of this phase 3, open-label, single-group clinical trial is to assess the efficacy of Boya IVIG in maintaining the mean number of serious bacterial infections to less than one per year in participants with primary…
- Trial name
- BoyaIVIG (NCT06150833)
- Testing
- Boya IVIG
- Volunteers
- 50 people
- Sponsor
- Azidus Brasil
Blepharospasm, Focal Dystonia
Brain Stimulation to Treat Blepharospasm or Meige Syndrome
This research study will examine whether magnetic or electrical stimulation of the brain can improve the involuntary closure of the eyelids in patients with blepharospasm or Meige syndrome; conditions that belong to a group of…
- Trial name
- NCT00411255
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Myocardial Infarction, Cardiovascular Disease
Thromboelastography As A Tool for Possible Clopidogrel Resistance in The Patients Treated With Primary PCI for STEMI
Determine usefulness of thromboelastography (TEG) as a valuable tool in ex-vivo assessing platelet response to aspirin and clopidogrel (dual) treatment and on-treatment platelet reactivity during acute ST segment elevation…
- Trial name
- NCT00517478
- Testing
- Blood Sample
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assaf-Harofeh Medical Center
Glaucoma, Primary Open Angle, Ocular Hypertension
A Study of Patients With Primary Open Angle Glaucoma or Ocular Hypertension Switched to Lumigan® UD Monotherapy for Medical Reasons
The study will evaluate patients diagnosed with primary open angle glaucoma or ocular hypertension who are switched to Lumigan® UD monotherapy for medical reasons in accordance with physician standard clinical practice.
- Trial name
- NCT01853085
- Testing
- Bimatoprost Ophthalmic Solution
- Where
- Germany
- Volunteers
- 1,830 people
- Sponsor
- Allergan
Breast Cancer Detection
Developing Screening Clinical Breast Examination Implementation Strategies in Nigeria
The goal of this observational study is to engage with multilevel stakeholders to collaboratively and to systematically develop a suite of strategies for implementing breast cancer screening using clinical breast examination…
- Trial name
- NCT07080515
- Where
- Nigeria
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yale University
Liver Cancer (Primary and Metastatic), Renal Cancer
Intra-procedural Spectral CT for Image-guided Embolization and Ablation in Interventional Oncology
This is a pilot study to evaluate the feasibility, image quality, and procedural utility of a novel spectral CT technique using Canon Medical's 4D CT system during image-guided interventional oncology procedures
- Trial name
- NCT07303725
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Palo Alto Veterans Institute for Research
Primary Aldosteronism
CETO First in Human Trial
The study is a Phase 1, single-centre, open label, micro-dosing study. The aim is to investigate an innovative new tracer, [18F]CETO, as a potential alternative to adrenal vein sampling for the lateralisation of primary…
- Trial name
- CETO (NCT04529018)
- Testing
- [18F]CETO
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
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