Clinical trials: Primary
Poverty, Income
addressInG iNcome securITy in Primary carE
Social processes that impact the health of individuals have been labeled the social determinants of health (SDOH). These are "the conditions in which people are born, grow, live, work and age.
- Conditions
- Poverty, Income, Social Determinants of Health
- Trial name
- IGNITE (NCT02459184)
- Testing
- Income Security Health Promotion
- Where
- Canada
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Blepharoptosis
Effect of Suture Material on Eyelid Height Stability After Anterior White-Line Advancement for Aponeurotic Ptosis.
What is the diagnosis and what treatment is indicated? The diagnosis is eyelid ptosis, which means drooping of the upper eyelid.
- Trial name
- WhiteLine_S (NCT07847749)
- Testing
- Anterior white-line advancement using an ABSORBABLE suture (POLYSORB 5-0). RED CODE., Anterior white-line advancement using a NON-ABSORBABLE suture (POLYPROPYLENE 5-0). BLUE CODE.
- Where
- Spain
- Volunteers
- 58 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Breast Cancer
A Study of Avastin (Bevacizumab) in Combination With Chemotherapy in Patients With Primary Breast Cancer
This study will evaluate the effect of Avastin (15mg/kg iv) in combination with Docetaxel and Xeloda, given as pre-operative therapy to patients with primary breast cancer.
- Trial name
- NCT02005549
- Testing
- bevacizumab [Avastin], docetaxel, capecitabine [Xeloda]
- Where
- Austria
- Volunteers
- 18 people
- Sponsor
- Hoffmann-La Roche
Primary Sjogren's Syndrome, Lymphoma
Chimeric Antigen Receptor Natural Killer Cell Therapy for High-risk Lymphoma Patients With Primary Sjogren's Syndrome
This study is a phase I-II clinical trial of CAR-NK cell therapy for high-risk lymphoma patients with primary Sjogren's syndrome (pSS).
- Trial name
- CAR-NK (NCT06967038)
- Testing
- CAR-NK cell
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Bangdong Gong
Primary Sclerosing Cholangitis
The Value of CT Cholangiography in Primary Sclerosing Cholangitis
The reason for this study is to see if a new radiologic technique called computerized tomographic cholangiography (CT cholangiography) could be helpful to demonstrate the bile ducts features and measure the amount of space of…
- Trial name
- NCT00588458
- Testing
- CT cholangiography
- Sponsor
- Mayo Clinic
Human Immunodeficiency Virus, Alcohol-Related Disorders
Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa
The purpose of this study is to evaluate a stepped care behavioral intervention for HIV medication adherence and substance use ("Khanya") integrated into an HIV primary care setting in South Africa.
- Conditions
- Human Immunodeficiency Virus, Alcohol-Related Disorders, Drug Use, Substance Use
- Trial name
- NCT05933226
- Testing
- Khanya
- Where
- South Africa
- Volunteers
- 160 people
- Sponsor
- University of Maryland, College Park
Infarction
Myocardial Infarction Safe Emergency Medicine Accompanying Study: Providing Reperfusion Therapy Within the Recommended Time Limits
The project is a prospective observational study with the aim of system improvement. It represents accompanying research in connection with the implementation of Safe Emergency Medicine , - an initiative under the auspices of the…
- Trial name
- NCT07092904
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- University Hospital of North Norway
Diabetes Mellitus, Heart Failure
Nt-proBNP Guided Primary Prevention of CV Events in Diabetic Patients
Increased levels of NT-proBNP are known to increase the risk of cardiac events in diabetic patients. The other way around, patients with normal values have an excellent prognosis on short-term.
- Conditions
- Diabetes Mellitus, Heart Failure, Coronary Artery Disease
- Trial name
- PONTIAC (NCT00562952)
- Testing
- Telmisartan, Bisoprolol
- Where
- 2 sites in Austria
- Volunteers
- 300 people
- Sponsor
- Medical University of Vienna
Solid Tumor, Colorectal Cancer
A Study of TRK-950 in Combinations With Anti-Cancer Treatment Regimens in Patients With Advanced Solid Tumors
The main purpose of this study is to establish the safety and the recommended dose of TRK-950 in combination with FOLFIRI, Gemcitabine / Cisplatin, Gemcitabine / Carboplatin, Ramucirumab / Paclitaxel, PD1 inhibitors (Nivolumab or…
- Conditions
- Solid Tumor, Colorectal Cancer, Cholangiocarcinoma, Bladder Cancer
- Trial name
- NCT03872947
- Testing
- TRK-950, Irinotecan, Leucovorin
- Where
- 14 sites in United States, France
- Volunteers
- 138 people
- Sponsor
- Toray Industries, Inc
Primary Insomnia, Psychophysiological Insomnia
Improving Sleep Quality in People With Insomnia
Insomnia is a significant problem affecting 10 to 20% of US population. Long-term pharmacological treatments are not recommended due to side effects, with therapy and sleep hygiene education often employed as alternatives.
- Trial name
- NCT02443649
- Testing
- Sleep hygiene program, Sleep hypnosis
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Malignant Neoplasms of Female Genital Organs, Ovarian Cancer
Bevacizumab in Ovarian Cancer Patients With Disease at Second-Look Surgery
The goal of this clinical research study is to learn if Avastin (bevacizumab) can help to control ovarian, fallopian, or primary peritoneal cancer that has been found during second-look surgery.
- Conditions
- Malignant Neoplasms of Female Genital Organs, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
- Trial name
- NCT02884648
- Testing
- Bevacizumab
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- M.D. Anderson Cancer Center
Premature Ovarian Failure
Endocan Levels in Women With Premature Ovarian Insufficiency
Objective: To evaluate serum endocan levels in women with premature ovarian insufficiency (POI) and to compare the results with those of healthy subjects.
- Trial name
- Endocan&POI (NCT03924648)
- Testing
- Endocan levels
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Cengiz Gokcek Women's and Children's Hospital
Multiple Chronic Conditions
Patient Priority Care for Older Adults With Multiple Chronic Conditions
Healthcare for older adults with multiple chronic conditions (MCCs) is burdensome and of uncertain benefit, resulting in unwanted and unhelpful care.
- Trial name
- PPC-CCF (NCT04510948)
- Testing
- Patient Priorities Care
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- The Cleveland Clinic
Lung Cancer, Lung Cancer Metastatic
ANET Electrosurgery Applicator Pilot Evaluation Study
Evaluate the preliminary safety and performance of the Electrosurgery Applicator (ANET device) during and after bronchoscopic ablation of a target pulmonary nodule/tumor.
- Trial name
- NCT03400748
- Testing
- RF Ablation
- Where
- 4 sites in United States, Canada
- Volunteers
- 6 people
- Sponsor
- Olympus Corporation of the Americas
Parkinson's Disease (PD), Parkinsonism
Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)
This study is designed to determine if magnetic resonance imaging (MRI) measures can be used to diagnose and monitor the progression of Parkinson's disease (PD) while distinguishing between PD and parkinsonisms [conditions that…
- Conditions
- Parkinson's Disease (PD), Parkinsonism, Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA)
- Trial name
- NCT01888185
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Suspected Primary Prostate Cancer
Evaluation of a Transrectal Scintigraphic Detector(ProxiScanTM) for Detection of Primary Prostate Cancer
This is a feasibility, exploratory, and proof-of-concept study to evaluate rectal probe scintigraphy device (ProxiScanTM) to detect PSMA specific radiopharmaceutical agent (ProstaScint®) in patients with suspected primary…
- Trial name
- NCT01359189
- Testing
- ProxiScan (scintigraphic rectal probe)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Overweight, Obesity
Primary Care Child Obesity Intervention Targeting Parents
Child overweight has become one of today's most important public health concerns. Engaged and skilled parenting that models, values, and encourages healthy eating habits and a physically active lifestyle can play a key role in…
- Trial name
- NCT01729910
- Testing
- Parent education / behavioral counseling, Usual Care
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- East Tennessee State University
Exfoliation Syndrome
Central Corneal Thickness in Glaucoma
The purpose of this study is to compare the central corneal thickness measurement in patients with exfoliation syndrome, exfoliative glaucoma, primary open-angle glaucoma, ocular hypertension and normal controls and to evaluate…
- Trial name
- NCT01023997
- Where
- Greece
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Myocardial Infarction
Safety of KAI-9803 for Injection With Angioplasty Following Heart Attack
Restoring blood flow to coronary arteries as quickly as possible is the best way to reduce the damage to the muscle that occurs with a heart attack.
- Trial name
- NCT00093197
- Testing
- KAI-9803 for Injection
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- KAI Pharmaceuticals
Cervical Cancer, Endometrial Cancer
Amifostine in Treating Women With Ovarian, Peritoneal, Cervical, Fallopian Tube, Uterine, or Endometrial Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Chemoprotective drugs, such as amifostine, may protect normal cells from the side effects of chemotherapy.
- Conditions
- Cervical Cancer, Endometrial Cancer, Fallopian Tube Cancer, Neurotoxicity
- Trial name
- NCT00003624
- Testing
- amifostine trihydrate, cisplatin, paclitaxel
- Where
- 8 sites in United States
- Sponsor
- Gynecologic Oncology Group
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