Clinical trials: Primary Headache Disorders
Chronic Migraine
Prophylactic Treatment With Atorvastatin for Chronic Migraine (ChronicStatinMig)
The main objective of this study is to see whether the favorable preventative effect of Atorvastatin 40mg per day in episodic migraine, that was found previously in three smaller randomized controlled cross-over studies, can be…
- Trial name
- NCT06485336
- Testing
- Atorvastatin 40mg
- Where
- 6 sites in Norway
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- St. Olavs Hospital
Migraine
Efficacy of Manual Therapy for the Treatment of Migraine.
Introduction According to the World Health Organization (WHO) at least 47% of adults have suffered from headache in the last year.
- Trial name
- MT-Migraine (NCT03555214)
- Testing
- Manual Therapy based on soft tissues, Control group, Manual Therapy based on structural techniques
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Valencia
Migraine, Headache, Tension-Type
Integrative and Complementary Therapy for Episodic Migraine and Tension-type Headache
This study is a monocentric uncontrolled observational study to evaluate a 12-14 day inpatient stay in an internal medicine clinic for integrative and complementary medicine for patients with episodic migraine and/or episodic…
- Trial name
- NAMIKOS (NCT06764914)
- Testing
- integrative and complementary medicine
- Volunteers
- 130 people
- Sponsor
- Kliniken Essen-Mitte
Migraine Without Aura, Migraine With Aura
Dose Ranging Study of the Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache
Primary objective: To investigate the efficacy and tolerability of two doses of tonabersat compared to placebo in the prophylaxis of migraine headache and to evaluate the longer term tolerability of tonabersat in an open label…
- Trial name
- TEMPUS (NCT00534560)
- Testing
- Tonabersat
- Volunteers
- 542 people
- Sponsor
- Minster Research Ltd
Tension-Type Headache, Unspecified, Intractable
Tension-Type Headache Gene Expression and Methylation
Tension-type headache (TTH) refers to pain radiating from the forehead to the back of the head as a bilateral band. It often occurs without warning and spreads to the neck muscles.
- Trial name
- TTH (NCT06562855)
- Testing
- Peripheral blood sampling
- Where
- 2 sites in Turkey (Türkiye)
- Sponsor
- University of Gaziantep
Migraine Disorders
A Multicenter Assessment of ALD403 in Chronic Migraine
The purpose of this study is to assess ALD403 in the prevention of migraine headache in chronic migraineurs.
- Trial name
- NCT02275117
- Testing
- ALD403
- Where
- 92 sites in United States, Australia and 2 more
- Volunteers
- 665 people
- Sponsor
- Alder Biopharmaceuticals, Inc.
Migraine
AI-assisted Migraine Education: Efficacy, Safety and Patients' Acceptance
Migraine affects 1 in 7 people globally, significantly impacting quality of life and economic productivity. Despite its prevalence, limited awareness leads to misdiagnosis, inadequate treatment, and stigmatization.
- Trial name
- NCT06507150
- Testing
- AI-assisted migraine education (AIME)
- Where
- Switzerland
- Volunteers
- 140 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Cluster Headache
Botox Injection in Treatment of Cluster Headache
Cluster headache is an intense and powerful, one-sided headache accompanied by involuntary symptoms such as red eye, droopy eyelids, flow of tears, small pupils and one-sided facial sweating.
- Trial name
- NCT02019017
- Testing
- Botulinum Toxin Type A 25 IU, Botulinum Toxin Type A 50 IU
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Migraine, Thrombophilia
Acute Phase Reactions and Thrombophilia in Pediatric Patients With Migraine
Acute Migraine attacks can be related to vascular or coagulation activation. Previous studies found relative high incidence of prothrombotic events in Migraine.
- Trial name
- NCT01905748
- Testing
- Laboratory tests
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- HaEmek Medical Center, Israel
Ear Noise, Tinnitus, Noise Induced
Multimodal Therapy for Somatosensory Tinnitus
Tinnitus (ringing or buzzing in the ears) affects approximately 10-15% of the adult population and significantly reduces quality of life in many patients.
- Conditions
- Ear Noise, Tinnitus, Noise Induced, Tinnitus, Subjective, Headache Other
- Trial name
- SOMATIN (NCT07468318)
- Testing
- Multimodal physiotherapy for TMJ and Cervical spine, Combined Exercise Program (Aerobic + Resistance + Breathing), Tinnitus-Specific Psychological Support
- Where
- Czechia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Charles University, Czech Republic
Headache Disorders, Influenza -Like Illness
InfluenCEF Study: Study on the Headache Associated With Influenza Infection
The goal of this observational analytic study with a cohort desing is to evaluate the epidemiology, risk factors and clinical phenotype of headache during Influenza infection.
- Conditions
- Headache Disorders, Influenza -Like Illness, Head Pain, Migraine
- Trial name
- INFLUENCEF (NCT05704335)
- Testing
- Questionnaire administration
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital Clínico Universitario de Valladolid
Tension-Type Headache
Effects of Exercise and Relaxation Techniques on Tension Headache Pain Parameters of University Students
Tension headache is a common disabling disease and a worldwide public health problem. This research tries to demonstrate the efficacy of physical therapy, based on cervical training and postural self-correction instructions…
- Trial name
- ERTTHU (NCT02264340)
- Testing
- Relaxation technique Autogenic Training, Combined treatment Autogenic Training + Cervical exercises and postural correction
- Volunteers
- 152 people
- Sponsor
- Universidad Complutense de Madrid
Migraine With Aura
PArtial REbreathing for Migraine With Aura 1
A prospective, multi-centre, randomized, double-blind, sham-controlled, parallel-group, group-sequential study to investigate safety and effectiveness of the Rehaler partial rebreathing device, in adults suffering from migraine…
- Trial name
- PAREMA1 (NCT05546385)
- Testing
- Partial Rebreathing Device
- Where
- 15 sites in United States, Germany
- Volunteers
- 142 people
- Sponsor
- Rehaler
Migraine Disorders
TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine
An evaluation of tablet disintegration and absorption and gastric transit of sumatriptan and naproxen sodium from a TREXIMA tablet and eletriptan from a RELPAX 40mg tablet.
- Trial name
- NCT00385008
- Testing
- Combination Product (sumatriptan succinate / naproxen sodium), RELPAX(eletriptan) 40mg Tablet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- GlaxoSmithKline
Migraine
MK3207 for Treatment of Acute Migraines (3207-005)
The purpose of the study is to demonstrate the effectiveness and appropriate dosage level of MK3207 in the treatment of acute migraine.
- Trial name
- NCT00712725
- Testing
- MK3207- 2.5 mg, MK3207- 5 mg, MK3207- 10 mg
- Volunteers
- 676 people
- Sponsor
- Merck Sharp & Dohme LLC
Migraine
Abortive Treatment of Migraine With the Cefaly® Abortive Program Device
The purpose of this study is to investigate the efficacy of the Cefaly® Abortive Program device used at home for 2 hours to treat a migraine attack.
- Trial name
- NCT03217968
- Testing
- Cefaly® Abortive Program device
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Cefaly Technology
Migraine, Headache
Is Topiramate Effective in Treating Dizziness in Patient's With Migraine-Associated Dizziness
The purpose of this study is to determine whether topiramate effective in treating dizziness symptoms that are associated with migraine headaches.
- Conditions
- Migraine, Headache, Dizziness
- Trial name
- NCT00732108
- Testing
- topiramate
- Where
- United States
- Sponsor
- University of California, San Francisco
Headache, Migraine
Carbon Monoxide's Headache Inducing Characteristics and Effects on the Cerebral Arteries and Blood Flow
In this study the investigators will research the hypothesis that the gas carbon monoxide induces headache and increases the blood flow velocity in the middle cerebral artery.
- Trial name
- NCT02066558
- Testing
- Carbon monoxide
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Migraine Without Aura
ACT Therapy for HF Migraine
The aim is to compare the effectiveness of a behavioral treatment, the Acceptance and Commitment Therapy, provided as an add-on to the prophylactic treatment (treatment as usual-TaU) against TaU only on the reduction of monthly…
- Trial name
- ACTMigraine (NCT03461874)
- Testing
- Education of patients, ACT, Pharmacological prophylaxis
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Migraine Headache
Peri-neural Electrical Dry Needling Migraine Treatment Study
This study seeks to determine the effectiveness of a specific treatment protocol using dry needling with perineural electrical stimulation in comparison to standard treatment in physical therapy for patients with migraine…
- Trial name
- NCT04252391
- Testing
- Perineural electrical dry needling, Standard Care
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wheaton Franciscan Healthcare
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.