Clinical trials: Primary Headache Disorders
Migraine
Research Study of Greater Occipital Nerve Block As A Treatment For Prolonged Migraine Attacks
Greater Occipital Nerve Blocks (GONB) are a common procedure used for the treatment of headache. The GONB procedure involves a series of injections into the greater occipital nerve (a spinal nerve located at the back of your…
- Trial name
- NCT00329732
- Testing
- 0.5% bupivicaine and 2% lidocaine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Thomas Jefferson University
Migraine
A Randomized, Multicenter, Study for the prEvention and Acute Treatment of Migraine (REAL)
This is a randomized study for the prevention and acute treatment of migraine using open label nVNS and standard of care versus standard of care. .
- Trial name
- REAL (NCT03787238)
- Testing
- non-invasive vagus nerve stimulation
- Where
- 17 sites in Denmark, Germany and 3 more
- Sponsor
- ElectroCore INC
Menstrual Migraine (MM) Headaches
Effectiveness And Safety Of Frovatriptan For The Management (Acute Treatment) Of Menstrual Migraine
Females 18 years of age or older with at least one year history of menstrual migraine (MM) headaches participated in a Phase 4 clinical trial to evaluate the efficacy of frovatriptan when used at the early stage (International…
- Trial name
- NCT00904098
- Testing
- Frovatriptan, Usual Care
- Where
- 21 sites in United States
- Volunteers
- 192 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Migraine
RELAXaHEAD for Headache Patients (Phase III)
This study is a fully powered, remote randomized control trial to evaluate RELAXaHEAD in people with migraine.
- Trial name
- NCT06077838
- Testing
- RELAXaHEAD Smartphone App Version 1, RELAXaHEAD Smartphone App Version 2
- Where
- United States
- Volunteers
- 450 people
- Sponsor
- NYU Langone Health
Migraine, Positional Vertigo
Clinical Aspects of Patients With Benign Paroxysmal Positional Vertigo (BPPV) and Migraine
The aim of this study is to analyze the clinical aspects of patients with BPPV associated with migraine. It is our purpose to clarify weather migraine is a risk factor for BPPV if the clinical aspect and the therapeutic outcome…
- Trial name
- NCT02615314
- Testing
- Particle re-positioning maneuver
- Volunteers
- 232 people
- Sponsor
- Anadolu Medical Center
Migraine Disorders
Long-Term Exposure to Rizatriptan 5-mg and 10-mg Oral Tablet (Combined Extension Protocols MK-0462-022, MK-0462-025, MK-0462-029)
This record describes pooled data for three extension studies: MK-0462-022 (NCT00897949); MK-0462-025 (NCT00899379); and MK-0462-029 (NCT00897104).
- Trial name
- NCT01286207
- Testing
- Rizatriptan 5 mg, Rizatriptan 10 mg, Standard Care
- Volunteers
- 1,959 people
- Sponsor
- Organon and Co
Migraine, Temporomandibular Joint Disorders
Changes and Associations Between Cervical Range of Motion, Pain, TMJ Range of Motion and Quality of Life in Migraineurs Applying Physical Therapy
The purpose of this study is to assess the effects of physiotherapy program and review the associations between neck movements, pain, temporomandibular joint (TMJ) movements and quality of life in individuals with migraine.
- Conditions
- Migraine, Temporomandibular Joint Disorders, Myofascial Trigger Point Pain
- Trial name
- NCT04729699
- Testing
- Aerobic exercise and exercise for TMJ, Aerobic exercise at home
- Where
- Lithuania
- Volunteers
- 19 people
- Sponsor
- Lithuanian University of Health Sciences
Craniofacial Pain, Migraine
Clinical Trial of Endoscopically Guided Injection of Exparel (Bupivacaine) for the Treatment of Craniofacial Pain
Exparel has a proven efficacy in providing pain relief for up to 72 hours with a single-dose administration at surgical sites. The study aims to evaluate the effectiveness of endoscopically-guided injection of Exparel…
- Conditions
- Craniofacial Pain, Migraine, Cluster Headache, Trigeminal Autonomic Cephalgia
- Trial name
- NCT04930887
- Testing
- Exparel (Bupivacaine Liposome), Saline
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Headache, Migraine Disorders
IV Haloperidol for the Treatment of Headache in the ED
Single center, double-blind, randomized, placebo-controlled trial evaluating analog pain scores in patients who present to the emergency department (ED) with a complaint of headache.
- Trial name
- NCT02747511
- Testing
- Haloperidol
- Volunteers
- 118 people
- Sponsor
- Western Michigan University School of Medicine
Migraine, Chronic Migraine
Introvision for Migraine and Headaches
To evaluate the effect of Introvision, a mental and emotional self-regulation-technique developed by Angelika C. Wager, as migraine preventative compared to a waiting list group.
- Trial name
- IntroMig (NCT03507400)
- Testing
- Introvision: mental and emotional self-regulation
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Chronic Cluster Headache
Sphenopalatine Ganglion Stimulation for the Treatment of Chronic Cluster Headache
The primary objective of the study is to demonstrate the safety and efficacy of SPG stimulation with the ATI Neurostimulation System when used to treat acute cluster attacks in chronic cluster headache patients.
- Trial name
- NCT02168764
- Testing
- ATI Neurostimulation System
- Where
- 24 sites in United States
- Volunteers
- 120 people
- Sponsor
- Autonomic Technologies, Inc.
Migraine
Migraine in Poland - a Web-based Cross-sectional Survey
A survey of Polish respondents will aim to define migraine characteristics in Polish subjects. To achieve this, a structured questionnaire based mainly on American Migraine Prevalence and Prevention Study has been prepared to…
- Trial name
- MIGinPOL2021 (NCT05087420)
- Where
- 2 sites in Poland
- Volunteers
- 2,800 people
- Sponsor
- Swiat Zdrowia
Migraine, Headache
Bioequivalence Study to Compare Ibuprofen/ Paracetamol Tablets (200mg Ibuprofen/ 500mg Paracetamol) Versus Nuromol® Tablets (200mg Ibuprofen/ 500mg Paracetamol)
Randomized, two-way, two-period, single oral dose, open-label, crossover, bioequivalence study to compare Ibuprofen/ Paracetamol tablets (200mg Ibuprofen/ 500mg Paracetamol) versus Nuromol® tablets (200mg Ibuprofen/ 500mg…
- Conditions
- Migraine, Headache, Backache
- Trial name
- NCT06180070
- Testing
- Ibuprofen/ Paracetamol tablets, Nuromol® tablets
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Humanis Saglık Anonim Sirketi
Migraine Disorder
An Open Label Trial of ALD403 (Eptinezumab) in Chronic Migraine
An evaluation of long term safety of repeat ALD403 doses in Chronic Migraine
- Trial name
- PREVAIL (NCT02985398)
- Testing
- ALD403 (Eptinezumab)
- Where
- 20 sites in United States
- Volunteers
- 128 people
- Sponsor
- Alder Biopharmaceuticals, Inc.
Transient Global Amnesia, Reversible Vasoconstriction Syndrome
Reversible Cerebral Vasoconstriction Syndrome With Concomitant Transient Global Amnesia
Reversible cerebral vasoconstriction syndrome (RCVS) is characterized by severe, unusual headaches associated with multifocal segmental vasoconstriction of the intracerebral arteries.
- Trial name
- NCT03739008
- Where
- France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Montpellier
Headache, Migraine, Chronic Migraine Headache
Stellate Ganglion Blockade for Refractory Chronic Migraine
Stellate Ganglion Block (SGB) is an interventional anesthetic technique used to treat pain conditions affecting the head, face, neck, and upper extremities by temporarily blocking sympathetic nerve output.
- Trial name
- SGB-RCM (NCT06891118)
- Testing
- Procedure/Surgery: Ultrasound-Guided Stellate Ganglion Block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Headache, Migraine Headache
A Preliminary Investigation of the Efficacy of Aromatherapy in Reducing Discomfort in Youth With Chronic Headache
The purpose of this study is to preliminarily establish the extent to which a brief aromatherapy intervention incrementally improves subjective and objective indicators of discomfort (pain, anxiety, and heart rate variability)…
- Conditions
- Chronic Headache, Migraine Headache, Headache
- Trial name
- NCT02440997
- Testing
- aromatherapy, foot bath
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Children's Mercy Hospital Kansas City
Migraine
Study of Oral Lasmiditan in Participants With Normal and Impaired Renal Function
This is a multi-center, open-label, non-randomized, parallel-group, adaptive, single dose study. This study will enroll up to 32 participants using an adaptive design that can include up to 3 groups of 8 participants with…
- Trial name
- NCT03009162
- Testing
- Lasmiditan
- Where
- 2 sites in Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Migraine
Effectiveness of a Dialogue-based Online Intervention Against Migraine
This trial was designed to evaluate the effectiveness of a dialogue-based online intervention (ceprica) that provides information regarding cognitive behavioural therapy (CBT) in patients with migraine.
- Trial name
- EU-OPTMi (NCT04276142)
- Testing
- ceprica (additional to treatment as usual), active control intervention (additional to treatment as usual)
- Where
- Germany
- Volunteers
- 321 people
- Sponsor
- Gaia AG
Migraine Headache
Study of Low-level Laser Therapy in the Acute Treatment of Migraine
This study evaluates the treatment of migraine pain using low energy laser light to quench migraine signals issuing from the sphenopalatine ganglion (SPG).
- Trial name
- NCT02969642
- Testing
- Argus Migraine Treatment device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The San Francisco Clinical Research Center
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