Clinical trials: Primary Health Care
Myocardial Infarction, Angina Pectoris
Natural Ischaemic Preconditioning Before First Myocardial Infarction
There is a sharp rise in the rate of coronary heart disease diagnoses and chest pain consultations in the 90 days before a first heart attack.
- Conditions
- Myocardial Infarction, Angina Pectoris, Coronary Heart Disease, Peripheral Arterial Disease
- Trial name
- NCT01604486
- Where
- United Kingdom
- Volunteers
- 16,000 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Type 2 Diabetes Mellitus (T2DM)
Diabetes Management for Primary Healthcare Centers.
The purpose of this study, "Integrating diabetes care into Primary Healthcare Centers (PHCs) in Abuja, Nigeria: a pilot study," is to screen, diagnose, treat, and educate diabetes patients in two selected PHCs in Abuja.
- Trial name
- DM4PHC-pilot (NCT06907472)
- Testing
- Protocol-based treatment
- Where
- 2 sites in Nigeria
- Volunteers
- 106 people
- Sponsor
- University of Abuja
Symptoms of Depression, Symptoms of Anxiety
Mindfulness-Based Cognitive Therapy for Depression and Anxiety
About 10-20% of older patients in primary care suffer from symptoms of depression and/or anxiety. Depression and anxiety are associated with higher rates of cognitive decline, lower quality of life, increased medical comorbidity…
- Trial name
- NCT02777905
- Testing
- Mindfulness Based Cognitive Therapy
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Lady Davis Institute
Dental Caries, Dry Mouth
Oral Health Intervention in Adult Primary Care
This study is a Stage III cRCT to test the efficacy of multi-level interventions at the practice- and provider-level to address low dental utilization (attendance) among Medicaid-enrolled older adults 55 years or older attending…
- Conditions
- Dental Caries, Dry Mouth, Periodontal Diseases, Bleeding Gum
- Trial name
- NCT06555029
- Testing
- EHR Changes, Medical Staff EHR Training, Clinician CSM theory-based didactic education and skills training, Standard ADA Oral Health Training
- Where
- United States
- Volunteers
- 929 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Post-Traumatic Stress Disorder in Children, Post-traumatic Stress Disorder
Adaptation of the PCIP for Children Aged 6 to 11
This study will implement a brief Post-traumatic Stress Disorder (PTSD) intervention for children, the Primary Care Intervention for PTSD (PCIP) delivered through telehealth (computer or smartphone delivery), to 10 youth age 6-11…
- Trial name
- NCT05606172
- Testing
- Primary Care Intervention for PTSD (PCIP) Youth aged 6 -11, Waitlist Treatment as Usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Depressive/Anxiety Symptoms, Depressive Disorder
Lifestyle Intervention for Symptoms of Depression wIth App Support in General Practice
The goal of this clinical trial is to find out whether a smartphone app can help reduce symptoms of depression by supporting healthy lifestyle changes and encouraging self-monitoring in adults who visit their general practitioner…
- Trial name
- LIDIAS (NCT07022184)
- Testing
- Personalized Lifestyle Intervention
- Where
- 3 sites in Netherlands
- Volunteers
- 216 people
- Sponsor
- Radboud University Medical Center
Patients in Complex Situations
A Quality Rating Scale for Patients in Complex Situations
The prevalence of multimorbid patients and complex care is increasing in France and elsewhere in the world. It concerns 60% of the over 65 years old.
- Trial name
- Qualsoprim_2 (NCT03886285)
- Testing
- Questionnaire
- Where
- 12 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Brest
Major Depressive Disorder
Storytelling Video Intervention for Depressed Primary Care Patients - Pilot Trial
The overall aim of this program of research is to refine and test a newly developed storytelling video intervention (sTVi) for depressed primary care patients.
- Trial name
- sTVi-RCT (NCT02311725)
- Testing
- aTAU + sTVi, aTAU + Attention Control Videos
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Butler Hospital
Nicotine Dependence, Cigarettes
Penn State TXT2Quit Study
This study is evaluating the feasibility and short term smoking cessation outcomes of an automated smoking cessation intervention delivered via mobile phone text messaging as an adjunct to Varenicline in a primary care setting.
- Trial name
- NCT02367391
- Testing
- Motivational Text Messages, Control
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Obesity, Diabetes Mellitus
Type 2 Diabetes Primary Prevention for At Risk Girls
Purpose: To evaluate two approaches to prevent obesity and type 2 diabetes in young girls. The Need: We are experiencing an epidemic of childhood obesity.
- Conditions
- Obesity, Diabetes Mellitus, Pre Diabetes
- Trial name
- NCT00063674
- Testing
- Nutrition Education, After-school dance class
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Disease
Improving Advance Care Planning by Preparing Diverse Seniors for Decision Making
The objective of this proposal is to test whether a multi-media website (www.prepareforyourcare.org) that is focused on preparing older adults for communication and medical decision making can help people engage in advance care…
- Trial name
- PREPARE (NCT01990235)
- Testing
- PREPARE Intervention
- Where
- United States
- Volunteers
- 541 people
- Sponsor
- University of California, San Francisco
Stress, Psychological, Burnout, Professional
Return to Work Among Patients With Stress Related Mental Disorders - An Intervention in the Swedish Primary Care
The aim of this project is to develop a model for return to work (RTW) for patients sick listed due to stress related mental disorders, which takes into account each patient's specific situation; includes the workplace, and is…
- Conditions
- Stress, Psychological, Burnout, Professional, Adjustment Disorders
- Trial name
- PRIMA (NCT03022760)
- Testing
- Work-related measures
- Where
- Sweden
- Volunteers
- 132 people
- Sponsor
- Vastra Gotaland Region
Alcohol Dependence
Study of 18 mg Selincro® As-needed Use, in the Treatment of Patients With Alcohol Dependence in Primary Care
To determine the reduction in alcohol consumption in patients with alcohol dependence treated with 18 mg Selincro® as-needed use, in conjunction with continuous psychosocial support in primary care
- Trial name
- NCT02195817
- Testing
- Selincro® 18 mg with continuous psychosocial support: Cohort A, Initial psychosocial support: Cohort B
- Where
- 48 sites in France, Germany and 2 more
- Volunteers
- 378 people
- Sponsor
- H. Lundbeck A/S
Asthma
Asthma Care With Alvesco® (Ciclesonide) in Primary Care in Adults - The ACCEPT-study (BY9010/CA-102)
The purpose of this study is to investigate the effectiveness of Alvesco® (Ciclesonide) compared with usual asthma care in the primary care setting.
- Trial name
- NCT00404547
- Testing
- Ciclesonide, Usual Care Inhaled Glucocorticosteroids
- Where
- 186 sites in Canada
- Volunteers
- 1,121 people
- Sponsor
- AstraZeneca
STEMI - ST Elevation Myocardial Infarction, Stent Thrombosis
TISSARA Trial: Ticagrelor Intervention to Reduce Stent Thrombosis and Acute MI Risk
Stent thrombosis (ST) remains a critical complication following primary percutaneous coronary intervention (PPCI) in patients with ST-elevation myocardial infarction (STEMI).
- Conditions
- STEMI - ST Elevation Myocardial Infarction, Stent Thrombosis, Antiplatelet Agents
- Trial name
- TISSARA (NCT06667349)
- Testing
- Ticagrelor
- Where
- Pakistan
- Volunteers
- 1,727 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Post-Traumatic Stress Disorder in Adolescence, Post Traumatic Stress Disorder
Adolescent PCIP Randomized Feasibility Trial
There are three research questions: (1) whether the Primary Care Intervention for PTSD (PCIP) improves health outcomes; (2) whether and how the PCIP can be sustainably delivered via telehealth; and (3) how PCIP compares to…
- Trial name
- APCIP (NCT05088915)
- Testing
- Primary Care Intervention for PTSD (PCIP), Treatment As Usual
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Diabetes Mellitus, Type 2
Paleolithic Diet in the Treatment of Diabetes Type 2 in Primary Health Care
There is uncertainty about the optimal diet in the prevention and treatment of diabetes type 2. Earlier studies have generally focused on intakes of fat, protein, carbohydrate, fiber, fruit and vegetables.
- Trial name
- NCT00435240
- Testing
- Paleolithic diet
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Lund University Hospital
Colorectal Neoplasms
The Magnitude of Effect of PCP Counseling on Participation Rate and Sedation Rate in Colonoscopy-based Screening Program
The purpose of this study is to assess the impact of physician's counseling on participation and utilization of sedation in a primary colonoscopy-based colorectal cancer (CRC) screening program
- Trial name
- NCT01688817
- Testing
- Physician's counseling, Information leaflet
- Volunteers
- 600 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Dental Caries
Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings
The study aims to develop a questionnaire that can be used to help uncover a child's risk of developing dental caries (also known as tooth decay or a cavity).
- Trial name
- NCT01707797
- Where
- 3 sites in United States
- Volunteers
- 1,326 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Major Depression, Dysthymia
Implementation of Harmonized Depression Outcome Measures in a Primary Care Registry and a Mental Health Registry
The purpose of this pilot project is to demonstrate feasibility and value of collecting harmonized outcomes measures for major depressive disorder (MDD) in two registries and combining the data to support patient-centered…
- Trial name
- NCT04235725
- Testing
- Harmonized Depression Outcome Measures
- Where
- 2 sites in United States
- Volunteers
- 953 people
- Sponsor
- OM1, Inc.