Clinical trials: Primary Immune Thrombocytopenia
Purpura, Thrombocytopenic, Idiopathic
The PROLONG Trial - Rituximab Maintenance Therapy in ITP
This study is a two phase study that aims to evaluate if low-dose Rituximab maintenance therapy may prolong the the effect of Rituximab in immune thrombocytopenia.
- Trial name
- NCT03010202
- Testing
- Dexamethasone, Rituximab
- Where
- Norway
- Volunteers
- 136 people
- Sponsor
- Ostfold Hospital Trust
Autoimmune Lymphoproliferative Syndrome, Autoimmune Cytopenia
Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation
The main objective of this study is to generate diagnosis and therapeutic-decision tools through the identification of molecular causes of PIDs with autoimmunity/inflammation and the variability in disease outcome at the…
- Conditions
- Autoimmune Lymphoproliferative Syndrome, Autoimmune Cytopenia, Autoimmune Diseases, Autoimmune Anemia
- Trial name
- ATRACTion (NCT04902807)
- Testing
- Collection of samples
- Where
- France
- Volunteers
- 325 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
HIV Infections, Primary Health Care
HIV Indicator Diseases in Hospital and Primary Care
Patients are frequently evaluated by physicians for medical work-up of HIV indicator conditions in hospital and in primary care at the general practitioner.
- Conditions
- HIV Infections, Primary Health Care, Acquired Immunodeficiency Syndrome, Sexually Transmitted Diseases, Viral
- Trial name
- #AwareHIV (NCT05225493)
- Testing
- Peer to peer feedback, HIV rapid test
- Where
- Netherlands
- Volunteers
- 1,500 people
- Sponsor
- Erasmus Medical Center
ITP - Immune Thrombocytopenia, Primary Immune Thrombocytopenia (ITP)
RESTI Registry: Spanish Registry of Primary Immune Thrombocytopenia and Other Immune Thrombocytopenia
Primary immune thrombocytopenia (PIT), previously referred to as idiopathic thrombocytopenic purpura, is an acquired disease characterized by accelerated platelet destruction and deficient platelet production by megakaryocytes.
- Trial name
- RESTI (NCT06919341)
- Where
- 36 sites in Spain
- Volunteers
- 1,000 people
- Sponsor
- Fundación Española de Hematología y Hemoterapía
Immune Thrombocytopenic Purpura
Health-related Quality of Life and Fatigue in Adult Patients With Primary Immune Thrombocytopenic Purpura (pITP)
Symptoms of Primary Immune Thrombocytopenic Purpura (pITP), such as spontaneous bruising, menorrhagia, mucosal bleeding and other symptoms might significantly affect the HRQOL of pITP patients.
- Trial name
- NCT01510873
- Testing
- HRQOL evaluation
- Where
- 29 sites in Italy
- Volunteers
- 424 people
- Sponsor
- Gruppo Italiano Malattie EMatologiche dell'Adulto
Purpura, Thrombocytopenic
ASPirin in Immune thRombocytopenia Patients With Cardiovascular disEase
The incidence of immune thrombocytopenia increases with older age. This population is at risk for arterial thrombosis. Due to an increased turn-over of platelets, low-dose aspirin once daily may be insufficient in this population…
- Trial name
- ASPIRE (NCT04912505)
- Testing
- Aspirin
- Where
- France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Toulouse
ITP - Immune Thrombocytopenia
Multi-target Drugs Sequential Combination Therapy in Adults Patients With Newly Diagnosed Primary Immune Thrombocytopenia
This prospective, single-arm, multicenter, exploratory study will enroll 38 adults patients with newly diagnosed primary immune thrombocytopenia (ITP).
- Trial name
- NCT07788456
- Testing
- standard-dose methylprednisolone/prednisone., thrombopoietin receptor agonist(TPO-RA), including but not limited to hetrombopag or eltrombopag., rituximab.
- Where
- China
- Volunteers
- 38 people
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Immune Thrombocytopenia
Rituximab, Eltrombopag and Dexamethasone as Frontline Treatment for Immune Thrombocytopenia
The purpose of this study is to determine the response rate and response duration with the combination of low-dose rituximab, eltrombopag and high-dose dexamethasone.
- Trial name
- NCT02834286
- Testing
- Rituximab, Eltrombopag, Dexamethasone
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Immune Thrombocytopenia
Alteration of Different Immune Parameters in Immune Thrombocytopenia （ITP） Patients Receiving Eltrombopag Treatment
This project was undertaken by Qilu Hospital of Shandong University and other well-known hospitals in China. In order to report the alteration of Different Immune Parameters in ITP Patients Receiving Eltrombopag Treatment.
- Trial name
- NCT01864512
- Where
- China
- Sponsor
- Shandong University
Corticosteroid-resistant or Relapsed ITP
A Study of Switching Avatrombopag and Rh-TPO in ITP
Thrombopoietin receptor agonists (TPO-RAs) represent a highly effective and well-tolerated second-line ITP treatment that provides excellent responses.If there is cross-resistance between 2 drugs for the treatment of adult ITP is…
- Trial name
- NCT04913597
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Primary Immune Thrombocytopenia
Andalusian Experience in the Use of Fostamatinib in Patients With ITP. FOSTASUR Study
Description of the use of fostamatinib in patients with PTI in the Andalusian region.
- Trial name
- NCT06071520
- Testing
- Fostamatinib
- Where
- 14 sites in Spain
- Volunteers
- 50 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla