Clinical trials: Primary Infertility
Premature Ovarian Failure
Autologous Mesenchymal Stem Cells Transplantation In Women With Premature Ovarian Failure
Stem cells (SC) are the foundation cells for every organ, tissue and cell in the body. They are undifferentiated "blank" cells that do not yet have a specific function.
- Trial name
- NCT02062931
- Testing
- Stem Cell Preparation and Injection
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sayed Bakry
Pregnancy, Infertility
Microsurgical Varicocelectomy Versus No Surgery in Men With a Palpable Varicocele and an Abnormal Semen Analysis
The primary research hypothesis is that microsurgical varicocelectomy will result in an increase in live birth in infertile couples where the male partner has a palpable varicocele and an abnormal semen analysis in comparison to…
- Trial name
- VIA (NCT00767338)
- Testing
- Timed intercourse, Microsurgical varicocelectomy, Intrauterine insemination
- Where
- 9 sites in United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Turner Syndrome, Infertility, Female
Turner Syndrome Minipuberty Study
Rationale: Due to accelerated germ cell loss, infertility is a major problem in girls with Turner syndrome (TS). Therefore, cryopreservation of ovarian tissue or oocytes before exhaustion of the ovarian reserve may preserve…
- Conditions
- Turner Syndrome, Infertility, Female, Premature Ovarian Failure, Gonadal Dysgenesis
- Trial name
- Minipuberty (NCT04189406)
- Testing
- Venapunction
- Where
- 13 sites in Denmark, Germany and 3 more
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Primary Female Infertility, Secondary Female Infertility
Effect of Traditional Chinese Medicine on In Vitro Fertilization (IVF) Success Rates
The purpose of this study is to determine the value of combining Traditional Chinese Medicine (TCM) Protocols including acupuncture with In Vitro Fertilization (IVF).
- Trial name
- TCM-P002 (NCT01331395)
- Testing
- Traditional Chinese Medicine
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Pacific Fertility Center
Primary Infertility Unspecified, Infertility
Routine Hysteroscopy in IVF/ICSI Cycles in Patients With Primary Unexplained Infertility
The aim of the present study is to evaluate the impact of hysteroscopy prior to starting the IVF (in vitro fertilisation) cycle on treatment outcome in women with unexplained primary infertility.
- Conditions
- Primary Infertility Unspecified, Infertility, Ovarian Hyperstimulation, Pregnancy
- Trial name
- NCT02416596
- Testing
- Hysteroscopy, Hysteroscope
- Volunteers
- 680 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Infertility, Female
Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in Women With Primary Infertility
We aim to assess the Safety and Efficacy of Cervical Lidocaine Prilocaine Spray in Reducing Pain During Hysterosalpingography in women with primary infertility
- Trial name
- NCT06769204
- Testing
- EMLA SPRAY
- Volunteers
- 90 people
- Sponsor
- Cairo University
Infertility, Female, Polycystic Ovary Syndrome
Polycystic Ovary Syndrome, Mitochondrial Dysfunction, Obesity, Insulin Resistance Infertility (POMODORI) Cohort
Enrolling of 150 female patients of fertile age diagnosed with PCOS, insulin resistance, infertility, or mitochondrial disease, and the same number of age- and sex-matched controls are planned.
- Conditions
- Infertility, Female, Polycystic Ovary Syndrome, Insulin Resistance, Primary Ovarian Insufficiency
- Trial name
- POMODORI (NCT06167135)
- Where
- Hungary
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Infertility
Low Dose hCG in the Late Follicular Phase
In this study,the investigators compared two protocols for controlled ovarian hyperstimulation in infertility patients requiring IVF. In the control group, the patient undergoes a standard antagonist protocol.
- Trial name
- NCT00750100
- Testing
- human chorionic gonadotropin, recombinant gonadotropins
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
Perimenopausal Disorder, Menopause
Inovium Ovarian Rejuvenation Trials
The Inovium Ovarian Rejuvenation Treatment is a PRP-based autologous treatment used in combination with a stimulated IVF sequence and Pre-Implantation Genetic Screening to treat infertility in women experiencing menopause…
- Conditions
- Perimenopausal Disorder, Menopause, Menopause, Premature, Menopause Related Conditions
- Trial name
- NCT03178695
- Testing
- Autologous PRP injection into human ovarian tissue
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ascendance Biomedical
Infertility Primary
The Aim of This Study is to Determine if Oocyte Sorting for Group Culture Using an Artificial Intelligence Image Analysis Tool (MagentaTM) Increases the Usable Blastocyst Yield and Subsequent Pregnancy in Patients Undergoing IVF
The aim of this study is to determine if oocyte sorting for group culture using an artificial intelligence image analysis tool (MagentaTM) increases the usable blastocyst yield and subsequent pregnancy in patients undergoing IVF.
- Trial name
- NiOS (NCT06521372)
- Testing
- Magenta AI image analysis tool
- Where
- 3 sites in United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Infertility, Sexuality
Sexual Counseling According to the PLISSIT Model in Primary Infertile Couples
This study was planned to determine the effect of sexual counseling given to primary infertile couples in line with the PLISSIT model on sexual function and sexual satisfaction.
- Conditions
- Infertility, Sexuality, Sexual Dysfunction, Nurse's Role
- Trial name
- NCT04791683
- Testing
- sexaul counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Primary Hypertension
Renal Denervation With Sterile Irrigated Deflectable Ablation Catheter Used in Renal Artery in Primary Hypertension
The purpose of this study is to assess the safety and efficacy of renal denervation with sterile irrigated deflectable ablation catheter used in renal artery in primary hypertension in China.
- Trial name
- NCT03511313
- Testing
- Renal denervation, Renal angiography
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Synaptic Medical Corporation
Primary Ovarian Insufficiency, Premature Ovarian Failure
A Therapeutic Trial of Human Amniotic Epithelial Cells Transplantation for Primary Ovarian Failure
This project will clarify the safety and effectiveness of human amniotic epithelial cells transplantation for the treatment of primary ovarian failure (POF) patients and provide a new therapeutic method for patients with…
- Conditions
- Primary Ovarian Insufficiency, Premature Ovarian Failure, Infertility
- Trial name
- POF (NCT02912104)
- Testing
- human amniotic epithelial cells (hAECs) transplantation
- Where
- China
- Volunteers
- 36 people
- Sponsor
- International Peace Maternity and Child Health Hospital
Pain
Effect of Music in Reducing Pain and Anxiety During Hysterosalpingography in Women With Primary Infertility
This study aims to demonstrate the value of music in lowering pain and anxiety during hysterosalpingography in women with primary infertility
- Trial name
- NCT06772636
- Testing
- music group, non music group
- Volunteers
- 110 people
- Sponsor
- Cairo University
Infertility, Female, IVF
Fertility Supportive Behavior Education Based On Watson's Theory Of Human Care
Infertile individuals frequently attempt behavioral changes to enhance the effectiveness of their treatment and improve fertility outcomes.
- Trial name
- NCT06591637
- Testing
- Fertility supportive behavior education based on Watson's Theory of Human Care, Routine nursing care, The booklet "Fertility-Supporting Health Training
- Where
- Palestinian Territories
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Primary Infertility
Analysis of Lipid Profiles in Samples Sperm and Seminal Plasma Under Artificial Insemination
Identify, by Lipidomics approaches, biochemical markers of fertility / infertility in sperm and seminal plasma linking the success or failure of the artificial insemination (IUI)
- Trial name
- NCT02704936
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- IVI Bilbao
Cancer
Study of Information Received About Fertility and Infertility in Patients Who Have Finished Treatment for Cancer
RATIONALE: Learning about the amount of information on fertility and infertility by patients before they received treatment for cancer in a comprehensive cancer center may help doctors plan the best treatment.
- Trial name
- NCT01295463
- Testing
- questionnaire administration, study of socioeconomic and demographic variables, assessment of therapy complications
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Institut Català d'Oncologia
Second Cancer, Survivorship
The Prospective Observational COMPRAYA Cohort Study
Rationale: Childhood cancer survivorship attracts attention globally, because successes in treatment have led to increasing number of survivors who reach adulthood, in which survivorship issues affecting health-related quality of…
- Conditions
- Second Cancer, Survivorship, Fertility Issues, Distress, Emotional
- Trial name
- COMPRAYA (NCT04682470)
- Testing
- No intervention ; observational
- Where
- Netherlands
- Volunteers
- 4,000 people
- Sponsor
- The Netherlands Cancer Institute
Osteoarthritis, Hip, Coxarthrosis; Primary
Osseointegration of THA Grafted by PolyNASS (ACTISURF-CERAFIT® ) Versus Non-grafted THA (CERAFIT®)
The infection rate after Total Hip Arthroplasty (THA) is about 1%. It is a serious condition, with high morbidity, sometimes fatal, requiring costly treatment.
- Conditions
- Osteoarthritis, Hip, Coxarthrosis; Primary, Coxarthrosis; Secondary, Osteonecrosis; Aseptic, Idiopathic
- Trial name
- NCT03113981
- Testing
- Total Hip Arthroplasty
- Where
- 7 sites in France
- Volunteers
- 340 people
- Sponsor
- Societe ACTIVBIOMAT
Primary Ovarian Insufficiency, Infertility
In Vitro Follicle Activation
The purpose of this study is to evaluate the effectiveness of an experimental treatment, known as in vitro activation (IVA) of dormant ovarian follicles, for infertility in women diagnosed with primary ovarian insufficiency (POI).
- Trial name
- IVA (NCT02496598)
- Testing
- In Vitro Follicle Activation (IVA), Follicle Activation
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- National Foundation for Fertility Research