Clinical trials: Primary Insomnia
Primary Insomnia
Efficacy and Safety of Circadin® 2 mg in the Treatment of Primary Insomnia Patients
This is a randomised, placebo controlled study to evaluate the efficacy of a 3 week treatment period with Circadin® 2 mg in shortening sleep latency in patients with primary insomnia aged 18-80 with melatonin deficiency.
- Trial name
- NCT00397189
- Testing
- Circadin
- Where
- United Kingdom
- Volunteers
- 930 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Primary Insomnia, Depression
Paroxetine in the Treatment of Chronic Primary Insomnia
The goal of the study is to examine the role of paroxetine, an antidepressant medication, in the acute and continuation treatment of insomnia.
- Trial name
- NCT00178048
- Testing
- paroxetine
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Pittsburgh
Sleep Initiation and Maintenance Disorders
Efficacy and Safety of M100907 on Sleep Maintenance Insomnia With a Sub-study in Stable Type II Diabetes Mellitus
The purpose of this study is to assess efficacy and safety of volinanserin in the population of patients complaining of sleep maintenance insomnia.
- Trial name
- SAMS12 (NCT00495885)
- Testing
- volinanserin (M100907)
- Where
- 16 sites in United States, Brazil and 14 more
- Volunteers
- 848 people
- Sponsor
- Sanofi
Insomnia, Sleep Deprivation
Study of the Effects of HIRREM-SOP for Insomnia
Prior research studies have shown benefit for use of a technique called High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), to reduce symptoms of moderate to severe insomnia.
- Trial name
- NCT03607994
- Testing
- HIRREM-SOP, NCC
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Primary Insomnia
Sleep Inducing And Maintaining Efficacy Of Circadin In Elderly Insomniacs
The aim of this placebo controlled study is to investigate the effect of 2 mg melatonin Slow Release (Circadin®) on the sleep/wake cycle in elderly insomniac out-subjects, aged 55 years or more.
- Trial name
- Neu I (NCT00816673)
- Testing
- Circadin
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Neurim Pharmaceuticals Ltd.
Primary Insomnia
A Dose-ranging, Multicenter Polysomnography Trial of PD 0200390 in Adults With Primary Insomnia
The purpose of this study is to further explore an effective dose range of PD0200390 for the treatment of patients with insomnia.
- Trial name
- NCT00551148
- Testing
- PD 0200390
- Where
- 16 sites in United States
- Volunteers
- 92 people
- Sponsor
- Pfizer
Insomnia, Primary, Insomnia
Occupation-based Sleep Program for People With Insomnia
Introduction. Sleep problems are a health issue worldwide. Based on the Person-Environment-Occupation-Performance model and the theory of occupational balance, we developed an occupation-based sleep program to address several…
- Trial name
- NCT04940975
- Testing
- Occupation-based sleep intervention program, Insomnia Education Program at Integrated Mental Health Clinic (IMHC)
- Where
- 2 sites in Hong Kong
- Volunteers
- 42 people
- Sponsor
- The Hong Kong Polytechnic University
Insomnia
A 2-Part Single Dose Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of E2006
Part A: The purpose of this study is to evaluate the safety and tolerability of single oral doses of E2006 administered in the morning to healthy male and female subjects.
- Trial name
- NCT01463098
- Testing
- E2006 1.0 mg, E2006 2.5 mg, E2006 5.0 mg
- Where
- 2 sites in United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Insomnia
Study of the Safety and Effectiveness of Esmirtazapine in Participants With Chronic Primary Insomnia (P05706)
The purpose of this study is to determine if esmirtazapine (Org 50081) is a safe and effective treatment for insomnia. It was anticipated that esmirtazapine would increase mean Total Sleep Time (TST) as recorded in sleep diaries…
- Trial name
- RUBY (NCT00482612)
- Testing
- Esmirtazapine
- Volunteers
- 526 people
- Sponsor
- Merck Sharp & Dohme LLC
Primary Dysmenorrhea
Functional Exercises With Water Intake in Primary Dysmenorrhea
Dysmenorrhea and its associated symptoms are very common in women. In Pakistan, almost 78% of women report Primary Dysmenorrhea. This will be a randomized controlled trial with two parallel groups.
- Trial name
- NCT05285475
- Testing
- Exercise and Water Intake
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Primary Insomnia
A Study of Gaboxadol in Primary Insomnia
To evaluate the efficacy safety and tolerability of gaboxadol in primary insomnia.
- Trial name
- NCT00209924
- Testing
- Gaboxadol
- Where
- Sweden
- Volunteers
- 505 people
- Sponsor
- H. Lundbeck A/S
Insomnia Disorder
Cannabinol Use in Patients With Insomnia Disorder
This study aims to investigate the acute effects of cannabinol (CBN) 30 mg and 300 mg, versus placebo, on sleep architecture and next-day functioning in adults aged 25-65 years with chronic insomnia disorder.
- Trial name
- CUPID (NCT05344170)
- Testing
- 30 mg Cannabinol (CBN), 300 mg Cannabinol (CBN)
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Woolcock Institute of Medical Research
Dysmenorrhea Primary
Binaural Beats Dysmenorrhea And Sleep Quality
The research is a randomized controlled trial. The sample group will consist of 120 people; 60 participants will be included in the experimental group, and 60 will be included in the control group.
- Trial name
- NCT06838936
- Testing
- Binaural Beats
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anxiety Disorders, Major Depression
CBT vs RTW Intervention for Patients With Common Subclinical Mental Illness in Primary Care
Background: Common mental illness, such as anxiety disorders and depression, is the main cause for sick leave in Sweden. Cognitive behavior therapy (CBT) has been shown to be effective in alleviating target symptoms of these…
- Conditions
- Anxiety Disorders, Major Depression, Stress Disorders, Primary Insomnia
- Trial name
- NCT01667809
- Testing
- Cognitive behavior therapy, Return to work
- Where
- Sweden
- Volunteers
- 5 people
- Sponsor
- Karolinska Institutet
Insomnia
Traditional Chinese Medicine Suan Tsao Jen Tang and Tian-Wang-Bu-Xin Dan in Patients With Primary Insomnia.
keywords： Traditional Chinese Medicine, Herbs, Clinical trial, Insomnia, Quality of life, Suan-Zao-Ren Tang, Tian-wang-bu-xin-dan
- Trial name
- NCT02319993
- Testing
- TIAN WANG BU XIN DAN, Suan Tzao Ren Tang
- Volunteers
- 128 people
- Sponsor
- Chung Shan Medical University
Primary Insomnia
A Pilot Study Of The Effects Of Microcurrent On Three Sleep Surveys
Participants identified as having primary insomnia will be randomly assigned to groups receiving microcurrent stimulation or sham in a double-blind randomized controlled trial.
- Trial name
- NCT00520832
- Testing
- Microcurrent
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Logan College of Chiropractic
Insomnia, Hypnotic Dependence
Enhancing Hypnotic Medication Discontinuation in Primary Care
Many individuals with insomnia seek treatment in primary care settings, where they often receive prescription hypnotic medications as their first and sometimes only treatment.
- Trial name
- NCT06435520
- Testing
- Digital Cognitive Behavioral Therapy, Structured Medication Tapering
- Where
- United States
- Volunteers
- 430 people
- Sponsor
- National Jewish Health
Insomnia Chronic
Feasibility and Acceptability of Cognitive Behavioral Therapy for Chronic Insomnia in a Primary Care
This pilot-feasibility study of a cluster parallel randomized design comparing CBT-i against usual care (UC) was performed at two primary health care centers in Majorca, Spain.
- Trial name
- NCT04565223
- Testing
- Cognitive behavioral therapy for insomnia
- Volunteers
- 32 people
- Sponsor
- Balearic Islands Health Service (Ibsalut)
Insomnia
Group Treatment for Insomnia in Primary Health Care
The aim of this study is to analyze if group treatment is effective to treat insomnia in primary healthcare.
- Trial name
- Sleep Prime (NCT01731223)
- Testing
- Group treatment for insomnia
- Where
- 2 sites in Sweden
- Volunteers
- 165 people
- Sponsor
- Jeanette Westman
Insomnia
Cognitive-Behavioural and Hypnotic Treatment of Chronic Primary Insomnia Among the Elderly
The present study examines the short- and long-term clinical efficacy of cognitive-behavior therapy and pharmacological treatment in patients suffering from late-life primary insomnia.
- Trial name
- NCT00295386
- Testing
- Cognitive behavior therapy (CBT), Zopiclone
- Where
- Norway
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Bergen