Clinical trials: Primary Percutaneous Coronary Intervention
Coronary Artery Disease, Ischemic Heart Disease
Culprit-first in Primary Percutaneous Coronary Intervention
The aim of this study is to assess the impact of culprit-first versus culprit-last percutaneous coronary intervention on the door to balloon time and clinical outcomes in patients with ST-elevation myocardial infarction.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Myocardial Infarction, STEMI
- Trial name
- NCT05415085
- Testing
- Culprit-first PCI
- Where
- Israel
- Volunteers
- 106 people
- Sponsor
- Shaare Zedek Medical Center
Safety Issues
Intracoronary Administration of OmniMSC-AMI for Acute ST-segment Elevation Myocardial Infarction Patients
This study will test the hypothesis intracoronary administration of OmniMSC-AMI (allogenic bone marrow-derived mesenchymal stem cells) just after finishing the primary percutaneous coronary intervention (PCI) in ST-segment…
- Trial name
- NCT05724576
- Testing
- OmniMSC-AMI
- Where
- Taiwan
- Volunteers
- 1 people
- Sponsor
- Taiwan Bio Therapeutics Inc.
Myocardial Infarction
Incheon-Bucheon Cohort of Patients Undergoing Primary PCI for Acute STEMI
INcheon-Bucheon cohorT of patients undERgoing primary percutaneous coronary intervention for acute ST-ELevation myocardiaL infARction (INTERSTELLAR) registry is a retrospective, observational, 4-regional-hospital based registry…
- Trial name
- NCT02804958
- Testing
- STEMI treated with primary PCI
- Where
- 4 sites in South Korea
- Volunteers
- 1,537 people
- Sponsor
- Gachon University Gil Medical Center
ST-elevation Myocardial Infarction, Multi Vessel Disease
Primary PCI in Patients With ST-elevation Myocardial Infarction and Multivessel Disease: Treatment of Culprit Lesion Only or Complete Revascularization
In patients with ST-elevation myocardial infarction (STEMI) the primary treatment is acute angioplasty of the acute occlusion (culprit lesion).
- Trial name
- PRIMULTI (NCT01960933)
- Testing
- Percutaneous coronary intervention, FFR
- Where
- 2 sites in Denmark
- Volunteers
- 650 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
ST-segment Elevation Myocardial Infarction (STEMI)
The Chinese STEMI PPCI Registry (CSPR)
The purpose of this study is to develop a risk score to predict the risks of in-hospital major adverse cardiac events in ST-segment elevation myocardial infarction patients treated by primary percutaneous coronary intervention.
- Trial name
- NCT04996901
- Testing
- no intervention
- Where
- China
- Volunteers
- 5,594 people
- Sponsor
- Renmin Hospital of Wuhan University
LCx Occlusion STEMI, STEMI
Outcomes of Isolated LCx Occlusion
To assess procedural success and short term clinical outcomes of primary PCI to isolated LCx acute occlusion.
- Trial name
- NCT06750328
- Volunteers
- 50 people
- Sponsor
- Assiut University
Myocardial Infarction, Ischemia
FIT (Fast Infarction Treatment): Complete Revascularization During Primary Percutaneous Coronary Intervention (PCI) Can be Achieved Safely With an Improved Clinical Outcome During the Indexed Hospitalization.
Few reports described outcomes of complete compared with infarct related artery (IRA) only revascularization in patients with ST elevation myocardial infarction (STEMI) and multivessel coronary disease (CAD).
- Conditions
- Myocardial Infarction, Ischemia, Heart Failure, Necrosis
- Trial name
- FIT (NCT01160900)
- Testing
- Coronary angioplasty all lesions
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- Azienda Ospedaliera San Camillo Forlanini
Myocardial Infarction, Percutaneous Coronary Intervention
Circulating PRCP in STEMI Patients Undergoing Primary PCI
Purpose: The purpose of this study is to evaluate the impact of acute ST-segment elevation myocardial infarction (STEMI) and primary percutaneous coronary intervention (PCI) on circulating prolylcarboxypeptidase (PRCP) level and…
- Conditions
- Myocardial Infarction, Percutaneous Coronary Intervention, PRCP
- Trial name
- NCT02772133
- Testing
- Primary PCI
- Where
- 4 sites in China
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Myocardial Infarction
Chronic Remote Ischemic Conditioning to Modify Post-MI Remodeling
During a heart attack, an artery carrying blood and oxygen to the heart becomes blocked, which causes damage to the heart muscle.
- Trial name
- CRIC-RCT (NCT01817114)
- Testing
- Auto Remote Ischemic Conditioning (AutoRIC) device
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN)
Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Contrast-Induced Nephropathy (CIN) is a serious complication following primary percutaneous coronary intervention (PCI) in patients presenting with acute ST-segment elevation myocardial infarction (STEMI).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN), Acute Kidney Injury
- Trial name
- NCT07826572
- Testing
- Total Ischemic Time Evaluation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
STEMI, Cardiovascular Disease
Vascular Healing After Implantation of FANTOM Bioresorbable Scaffold in STEMI: A FANTOM STEMI Study
The study will assess the safety and performance of the Fantom sirolimus eluting bioresorbable vascular scaffold (BVS) in the acute setting of myocardial infarction with unstable lesions and thrombogenic milieu.This is a…
- Conditions
- STEMI, Cardiovascular Disease, Bioresorbable Scaffold
- Trial name
- FANTOM STEMI (NCT03785431)
- Testing
- PCI with Phantom Bioresorbable Scaffold
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Medical University of Warsaw
ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention
The EPIVER Randomized Controlled Trial
The trial aims to estimate the efficacy and safety of the intracoronary administration of adrenalin, verapamil, as well as their combination compared to standard treatment in patients with STEMI and refractory coronary no-reflow…
- Conditions
- ST Elevation Myocardial Infarction, Percutaneous Coronary Intervention, No-Reflow Phenomenon
- Trial name
- EPIVER (NCT04573751)
- Testing
- Standard therapy, Epinephrine, Verapamil
- Where
- Russia
- Volunteers
- 104 people
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Myocardial Infarction
Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Reactivity in Patients With ST-elevation Myocardial Infarction (STEMI)
This is a single-center, randomized, single-blind, investigator-initiated, pharmacological study with a parallel design. Patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention and…
- Trial name
- PRO-GR-4 (NCT01338909)
- Testing
- Prasugrel, Clopidogrel
- Where
- Greece
- Volunteers
- 35 people
- Sponsor
- University of Patras
Myocardial Infarction, Echocardiography 2D
Left Ventricular Function After Primary Percutaneous Coronary Intervention: Role of Speckle Echocardiography
Recovery of the left ventricular function is variable from one patient to another, thus assessment of cardiac function by measuring left ventricular ejection fraction using echocardiography is the most common in the daily…
- Conditions
- Myocardial Infarction, Echocardiography 2D, Left Ventricular Dysfunction
- Trial name
- NCT04103008
- Testing
- Speckle tracking echocardiography
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Myocardial Infarction
Diagnostic and Prognostic Utility of Pentraxin 3 in Patients With Acute STEMI Undergoing Primary PCI
A number of inflammatory markers have been recognized, among which the acute phase reactant C-reactive protein showed a positive correlation with the risk of coronary artery disease in both healthy individuals and those at high…
- Trial name
- NCT03476252
- Testing
- pentraxin 3
- Volunteers
- 100 people
- Sponsor
- Assiut University
ST Segment Elevation Myocardial Infarction (STEMI), No Reflow Phenomenon
The Investigator Administers Intracoronary Adrenaline Via the Catheter in STEMI Patients During Primary PCI, After Flow Restoration and Before Stenting, and Studies Its Effect in Prevention of No Reflow
The aim of this work is to study the role of intracoronary adrenaline administration as a preventive tool for no reflow in patients undergoing primary PCI.
- Trial name
- NCT06847568
- Testing
- Adrenaline
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Ain Shams University
Acute Myocardial Infarction
Correlation of Blood Serum Renalase and Microcirculation Obstruction in Patients with Acute Myocardial Infarction After Primary Percutaneous Coronary Intervention
This research will explore the association between blood serum renalase and microcirculation obstruction in patients with acute myocardial infarction (AMI) after primary percutaneous coronary intervention (PCI).
- Trial name
- NCT06669520
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Left Main Coronary Artery Disease, Left Anterior Descending Coronary Artery Stenosis
Prospective Evaluation for Hybrid Cardiac Procedures
Multidisciplinary team-approach in order to offer personalized treatments represents the emerging mainstream in cardiovascular medicine.
- Conditions
- Left Main Coronary Artery Disease, Left Anterior Descending Coronary Artery Stenosis, Valve Disease, Heart, Carotid Stenosis
- Trial name
- PERHAPS (NCT05143671)
- Testing
- Coronary artery bypass grafting, Percutaneous coronary intervention, Surgical valve replacement
- Where
- Italy
- Volunteers
- 134 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Primary PCI
Different β -Blockers in STEMI and Primary PCI
Carvedilol, target dose: 50 mg daily; Bisoprolol, target dose: 10 mg daily; Metoprolol tartrate, target dose: 150 mg daily; Metroprolol succinate, target dose: 200 mg daily
- Trial name
- NCT04221919
- Testing
- β -Blockers
- Volunteers
- 1,200 people
- Sponsor
- Qilu Hospital of Shandong University
STEMI (ST Elevation MI), STEMI - ST Elevation Myocardial Infarction
Effect of Guanxinning Tablet on Coronary Microcirculation After Primary Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction
①Research objective: In a small sample population, through the pre - experimental method, explore and evaluate the effect of Guanxinning tablets on the coronary microcirculation after primary percutaneous coronary intervention…
- Conditions
- STEMI (ST Elevation MI), STEMI - ST Elevation Myocardial Infarction, STEMI, CMD
- Trial name
- NCT07621107
- Testing
- Guanxinning Tablet(GXNT)
- Volunteers
- 70 people
- Sponsor
- Beijing Anzhen Hospital