Clinical trials: Primary Prevention
Primary Prevention of Sudden Cardiac Arrest, Secondary Prevention of Sudden Cardiac Arrest
S-ICD® System Post Approval Study
The purpose of the S-ICD Post Approval Study is to document long term safety and effectiveness outcomes associated with the implantation of the SQ-RX pulse generator and Q-TRAK electrode in a commercial clinical setting.
- Trial name
- NCT01736618
- Testing
- S-ICD System
- Where
- 87 sites in United States
- Volunteers
- 1,766 people
- Sponsor
- Boston Scientific Corporation
Primary Prevention, Questionnaire and Survey
Prevention in Belgian Hockey : What Does the Staff Really Put in Place?
Purpose: To provide an update on the implementation of prevention among hockey players by their entourage. Materiel and method: This study will be conducted by the means of a questionnaire.
- Conditions
- Primary Prevention, Questionnaire and Survey, Hockey Player
- Trial name
- NCT04977154
- Testing
- Primary prevention
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Liege
Primary Prevention
FIT FIRST FOR ALL - The Dose-Response Study
In the present study, FIT FIRST 10 will run over 20 weeks, with cardiometabolic fitness as the primary outcome and project acceptability as the co-primary outcome.
- Trial name
- NCT06180772
- Testing
- FIT FIRST
- Where
- Denmark
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Statin Treatment for Primary Prevention
STREAM Trial - Biomarker
Statins are among the most widely used drugs. While they were found to be effective for primary and secondary prevention of cardiovascular disease (CVD) in middle-aged subjects, their benefits for primary prevention in older…
- Trial name
- STREAM-Bio (NCT05482386)
- Testing
- Statin discontinuation
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Statin Treatment for Primary Prevention
STREAM Trial - Subclinical Atherosclerosis
Statins are among the most widely used drugs. While they were found to be effective for primary and secondary prevention of cardiovascular disease (CVD) in middle-aged subjects, their benefits for primary prevention in older…
- Trial name
- STREAM-SubATS (NCT05482399)
- Testing
- Statin discontinuation
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hypercholesterolemia, Primary Prevention
Phytosterol Supplementation and Lipoprotein Subfractions
The goal of this clinical trial was to evaluate the effects of phytosterol supplementation to the diet on lipids, LDL and HDL subfractions, and on the quality of LDL in apparently healthy subjects.
- Trial name
- Phyto (NCT06127732)
- Testing
- Phytosterol supplements
- Where
- 2 sites in Brazil
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Valvular Heart Disease, Implantable Cardioverter Defibrillator
Benefits of ICD for the Primary Prevention in Patients With Valvular Cardiomyopathy
The prevalence of valvular heart disease is on the rise along with the aging society and the generalization of echocardiography.
- Conditions
- Valvular Heart Disease, Implantable Cardioverter Defibrillator, Sudden Cardiac Death, Primary Prevention
- Trial name
- BEAT (NCT03590730)
- Testing
- ICD implantation
- Where
- 12 sites in South Korea
- Volunteers
- 12 people
- Sponsor
- Keimyung University Dongsan Medical Center
Neck Pain, Exercise Therapy
Prevention of Neck Pain in Adults With a Back School-Based Intervention.
The study consists of a theoretical and practical intervention based on the Back School. This intervention will be carried out over 8 weeks with a frequency of two sessions per week, for a total of 16 sessions of 45 minutes…
- Conditions
- Neck Pain, Exercise Therapy, Health Education, Primary Prevention
- Trial name
- NCT05260645
- Testing
- Back School
- Where
- Spain
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Vigo
Adolescent - Emotional Problem, Mental Health Wellness 1
A Primary Prevention Intervention for the Promotion of Psycho-social Wellbeing in Adolescent Young Carers:
Adolescent young carers (AYCs) are young people aged 15-17 years old, who take on significant or substantial caring tasks and assume a level of responsibility that would usually be associated with an adult.
- Conditions
- Adolescent - Emotional Problem, Mental Health Wellness 1, Caregivers, Primary Prevention
- Trial name
- ME-WE (NCT04114864)
- Testing
- Psycho-educational sessions
- Where
- 6 sites in Italy, Netherlands and 4 more
- Volunteers
- 295 people
- Sponsor
- Valentina Hlebec
Primary Prevention
Using Boot Camp Translation to Address Rural Disparities in Adolescent Vaccination
The overall goal of this project is to implement the Boot Camp Translation process to develop a replicable approach for increasing adolescent vaccine uptake that can be adaptable and feasible to use in rural settings more broadly.
- Trial name
- RADVax (NCT03955757)
- Testing
- Boot Camp Translation, Control
- Where
- United States
- Volunteers
- 6,000 people
- Sponsor
- University of Colorado, Denver
Cardiovascular Primary Prevention Strategy
Role of Screening With Coronary Computed Tomography Angiography in Primary Prevention of Coronary Heart Disease
The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy will be superior to traditional CHD prevention strategy, in…
- Trial name
- RESPECT (NCT05431309)
- Testing
- Coronary Computed Tomography Angiography, Standard Treatment
- Volunteers
- 15,000 people
- Sponsor
- Jinling Hospital, China
Cardiometabolic Disease, Health Coaching
A Feasibility Study of a Health Coaching Programme for Middle-aged Adults With Cardiometabolic Risk
Cardiometabolic disease has been an increasing trend globally and remains the major cause of morbidity and mortality. Health coaching, a process of goal-oriented and client-centered partnership that is health-focus and through…
- Conditions
- Cardiometabolic Disease, Health Coaching, Middle-aged Adults, Primary Prevention
- Trial name
- NCT05444140
- Testing
- Health coaching
- Where
- Hong Kong
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Cardiovascular Disease, Stroke
Effects of Message Framing and Time Discounting on Health Communication for Optimum Cardiovascular Disease and Stroke Prevention
Effects of Message framing and Time discounting on heath communication for Optimum Cardiovascular disease and Stroke Prevention（EMT-OCSP）is a pragmatic, 2 × 2 factorial, randomized, controlled, observer blinded, multicenter trial…
- Conditions
- Cardiovascular Disease, Stroke, Primary Prevention
- Trial name
- EMT-OCSP (NCT04450888)
- Testing
- The strategic use of messages in risk communication
- Where
- China
- Volunteers
- 13,114 people
- Sponsor
- West China Hospital
Primary Prevention
Prevention Program- Promoting Self Resilience, Positive Self-Image and Body Image Among Adolescents and Their Parents
Cluster-Randomized Clinical trial, which includes the development and activation of an intervention program among young adolescents and their parents.
- Trial name
- NCT03540277
- Testing
- Experimental: Prevention Program "young In Favor of Myself", active parents, Experimental: Prevention Program "young In Favor of Myself", no parental involvement
- Where
- Israel
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Musculoskeletal Manipulations, Primary Prevention
Effects of Perineal Massage (PERMAS)
Perineal massage increases elasticity of myofascial perineal tissue and decreases the burning and perineal pain during labour, thus optimizing child birth, although an application protocol has not been standardized yet.
- Conditions
- Musculoskeletal Manipulations, Primary Prevention, Obstetric Labor Complications, Physical Therapy Modalities
- Trial name
- PERMAS (NCT05114811)
- Testing
- Self-provided perineal massage, Physiotherapist perineal massage: manual and instrumental (with EPI-NO)
- Where
- Spain
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Primary Prevention
A Prevention Program to Encourage Self-care, Self-esteem and Body-esteem Among Young Adolescents
Cluster-Randomized Clinical trial, which includes the development and activation of an intervention program among young adolescents and their parents.
- Trial name
- NCT05103371
- Testing
- Experiment: "Millie" prevention program, adolescents and active parents, Experiment: "Millie" prevention program, adolescents only
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Primary Prevention
Increasing the Impact of a School Prevention Program Among Young Adolescents by Adding a Teacher Component
A randomized clinical trial in clusters, including the development and implementation of an intervention program among young adolescents and their teachers.
- Trial name
- NCT05102526
- Testing
- Experimental: "Young Millie" prevention program, active teachers, Prevention program: "Young Mili", non active teachers
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Primary Prevention
Adolescents as Change Agents in the Incorporation of a Parental Component for a School Based Prevention Program
Cluster-Randomized Clinical trial, which includes the development and activation of an intervention program among young adolescents and their parents.
- Trial name
- NCT04688619
- Testing
- Prevention Program "young In Favor of Myself", active parents, Prevention Program "young In Favor of Myself", no parental involvement
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Primary Prevention
Increasing the Effect of a School-based Prevention Program by Teacher Involvement
Cluster-Randomized Clinical trial, which includes the development and activation of an intervention program among young adolescents and their teachers.
- Trial name
- NCT04682613
- Testing
- Experimental: Prevention Program "young In Favor of Myself", active teachers, Experimental: Prevention Program "young In Favor of Myself", no teacher involvement
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Type 2 Diabetes Mellitus, Primary Prevention
The Impact of a Diabetes Risk Prediction Model in Primary Care.
Little evidence exists on the impact of diabetes risk scores, e.g. on physicians and patient's behavior, perceived risk of persons, shared-decision making and particularly on patient´s health.
- Trial name
- NCT03234322
- Testing
- external validated risk prediction model
- Where
- Germany
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- German Diabetes Center