Clinical trials: Primary Total Hip Replacement
Osteoarthritis, Hip, Total Hip Arthroplasty
Effect of Single vs Multiple Prophylactic Antibiotic Doses on PJI Following Primary THA in Patients With OA
Aim: To compare the effect of one single dose versus multiple doses of prophylactic antibiotics administered within 24 hours, on the development of PJI in patients with osteoarthritis undergoing primary THA.
- Conditions
- Osteoarthritis, Hip, Total Hip Arthroplasty, Prosthetic-joint Infection
- Trial name
- ProHipQ-OA (NCT05530551)
- Testing
- Antibiotic dosage practice
- Where
- 36 sites in Denmark
- Volunteers
- 20,000 people
- Sponsor
- Soren Overgaard
Arthropathy of Knee, Osteo Arthritis Knee
Meditation and Opioid Consumption in Total Joint Replacement Patients Undergo Primary Total Hip and Knee Replacement
The main purpose of this study is to look at whether meditation techniques can help reduce pain and opioid use after surgery.
- Conditions
- Arthropathy of Knee, Osteo Arthritis Knee, Osteonecrosis, Meditation
- Trial name
- NCT05669066
- Testing
- Mindful meditation
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Arthroplasty Total Hip Replacement
The Relationship Between Operative and Radiologic Stem Version
Investigators prospectively evaluate the accuracy of intraoperative stem anteversion in 40consecutive total hip arthroplasties.
- Trial name
- NCT02552173
- Testing
- The Relationship Between Operative and Radiologic Stem Version
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Arthroplasty, Replacement, Hip, Hip Replacement, Total
Does Rapid Mobilisation Improve Length of Stay and Outcomes Post THR
This study looks to examine the effect of attempting initial postoperative walking with a patient following a total hip replacement.
- Trial name
- RAPID (NCT02428829)
- Testing
- Attempt walking from 4 hours post operatively, on the day of their surgery., Control - standard treatment
- Where
- United Kingdom
- Volunteers
- 212 people
- Sponsor
- The Royal Bournemouth Hospital
Total Hip Arthroplasty (THA)
Comparing Outcomes of Labrum Preservation vs Excision in Primary Total Hip Arthroplasty
This research is being done to determine whether removing or preserving the acetabular labrum, a ring of cartilage around the hip socket, during hip replacement surgery affects post-operative outcomes, operative time, or ease of…
- Trial name
- NCT07812025
- Testing
- Labrum Preservation, Labrum Excision
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Total Joint Specialists
Coxarthrosis; Primary
Evaluation of Proprioception in Patients With Total Hip Replacement
Disturbances of balance and postural stability are frequent in patients with coxarthrosis due to the damage to the mechanoreceptors, characteristic of arthritic degeneration, and muscular hypotrophy of the affected limb.
- Trial name
- PROPRIO-ATA (NCT05763368)
- Testing
- Clinical tests and proprioception evaluation
- Where
- Italy
- Sponsor
- Istituto Ortopedico Rizzoli
Knee Replacement, Hip Replacement
Perioperative Hyperglycaemia in Primary Total Hip and Knee Replacement
The purpose of this study is to analyze how common stress hyperglycaemia (abnormally high blood glucose) is in primary hip and knee replacement surgeries and which factors predispose to hyperglycaemia.
- Conditions
- Knee Replacement, Hip Replacement, Hyperglycemia
- Trial name
- HyTe-1 (NCT01021826)
- Where
- Finland
- Volunteers
- 193 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Osteoarthritis
A Randomized Controlled Trial of Long Versus Short Wait For Primary Total Hip and Knee Arthroplasty
The primary research question is: Does expedited hip and knee replacement result in improved lower-extremity function at 36 months post randomization as measured by the Western Ontario McMaster Universities Osteoarthritis Index…
- Trial name
- NCT00138892
- Testing
- Waiting time (access time to Total joint replacement)
- Where
- Canada
- Volunteers
- 236 people
- Sponsor
- University of British Columbia
Primary Hip Osteoarthritis, Secondary Hip Osteoarthritis Due to Idiopathic Femoral Head Necrosis, Childhood or Inflammatory Disease
Fitmore Versus CLS Stem in Total Hip Arthroplasty. Bilateral One-stage Operations
Main question: Will use of a stem design that allows anatomical reconstruction of the hip joint improve the outcome in terms of hip function and patient satisfaction without causing any adverse effects? Background: Total hip…
- Conditions
- Primary Hip Osteoarthritis, Secondary Hip Osteoarthritis Due to Idiopathic Femoral Head Necrosis, Childhood or Inflammatory Disease, Bilateral Hip Disease, Surgical Treatment
- Trial name
- NCT03112785
- Testing
- Total hip arthroplasty (Fitmore or CLS uncemented femoral stem made by Zimmer-Biomet, Warshaw, USA)
- Volunteers
- 44 people
- Sponsor
- Sahlgrenska University Hospital
Osteoarthritis of Hip, Failure of Primary THA
Stability of Revision Total Hip Arthroplasty Implants Using Radiostereometric Analysis
The specific aim is to quantify the stability of the acetabular and femoral components of a revision total hip arthroplasty (THA) in vivo as currently performed at our institution.
- Trial name
- NCT01668160
- Testing
- Bead placement during revision hip replacement surgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Primary Total Knee Arthroplasty, Primary Total Hip Arthroplasty
Investigating the Effect of Intravenous and Oral Tranexamic Acid on Blood Loss After Primary Hip and Knee Arthroplasty
Patients having a hip or knee replacement can lose almost a third of their blood during and after the operation. Many patients, especially those who are older will need a blood transfusion, suffer from anaemia, or have a slow…
- Trial name
- TRAC-24 (NCT03690037)
- Testing
- Tranexamic Acid 100 MG/ML, Tranexamic Acid 500 MG
- Where
- United Kingdom
- Volunteers
- 1,089 people
- Sponsor
- Belfast Health and Social Care Trust
Primary Osteoarthritis, Cartilage Degeneration
DEXA Bone Density Analysis of the CoreHip® Prosthesis System
The goal of this interventional post-market follow-up study is to evaluate radiological changes in the diaphyseal bone density (Gruen Zones 3 and 4) within 24 months postoperative in patients treated with CoreHip® primary…
- Conditions
- Primary Osteoarthritis, Cartilage Degeneration, Osteoarthritis, Hip, Inflammatory Arthritis
- Trial name
- CODEX (NCT06632301)
- Testing
- Primary hip replacement with cementless stem
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Aesculap AG
Revision Total Hip Arthroplasty, Primary Total Hip Arthroplasty
Retrospective Observational Cohort Study of SYMBOL CUP DM 2
This is a single-center retrospective observational cohort study of consecutively operated patients who underwent total hip arthroplasty (THA) with a SYMBOL CUP DMR HA or a SYMBOL CUP DM CEM hemispherical dual mobility acetabular…
- Trial name
- SYMCOR-2 (NCT04209426)
- Testing
- THA with SYMBOL CUP DMR HA, THA with SYMBOL CUP DM CEM
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Dedienne Sante S.A.S.
Arthroplasty
Cardiovascular Changes and Changes in Tissue Oxygenation During Early Postoperative Mobilization in Total Hip Arthroplasty (THA) Patients
The purpose of this study is to investigate the cardiovascular changes during early postoperative mobilization of hip arthroplasty patients.
- Trial name
- NCT01089946
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet