Clinical trials: Probe-based Confocal Laser Endomicroscopy
Obesity
Identification of In-vivo Probe Based Confocal Laser Endomicroscopy Cellular Characteristics in Obese Women
Previous studies have shown that histological changes in the gastric mucosa between obese and non-obese individuals do exist. Understanding these histological differences (between obese and non-obese individuals) might elucidate…
- Trial name
- NCT02781961
- Testing
- cellvizio
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Sheba Medical Center
Flow Determination
Real-time Observation of Microcirculatory Hemodynamics in Gastric Intestinal Metaplasia by Confocal Laser Endomicroscopy
The morphologic change of microvessels has the clinical value to distinguish cancerous from non-cancerous mucosa. The aim of this study was to observe gastric mucosa microcirculatory hemodynamic changes real-time using pCLE…
- Trial name
- NCT02595151
- Testing
- CLE
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Shandong University
Colorectal Cancer
Optical Biopsy for Peritoneal Nodules in Colorectal Patients
During surgery, peritoneal metastasis is typically confirmed pathologically through resection sample. However, this process can be time-consuming when utilizing intro-operative frozen section pathology.
- Trial name
- NCT05879783
- Testing
- Confocal laser endomicroscopy
- Where
- China
- Volunteers
- 278 people
- Sponsor
- Nanfang Hospital, Southern Medical University
COVID-19
Probe-based Confocal Laser Endomicroscopy in Critically Ill COVID-19 Patients
The study is devoted to the comparative analysis of the data received in patients with COVID-19 lung pathology using the method of probe-based confocal laser endomicroscopy of distal airways and two reference methods: high…
- Trial name
- NCT04451889
- Testing
- miniprobe Alveoflex
- Where
- Russia
- Volunteers
- 15 people
- Sponsor
- Federal Research Clinical Center of Federal Medical & Biological Agency, Russia
Gastric Intestinal Metaplasia
Magnified Intelligence Chromoendoscopy Plus Probe-based Confocal Laser Endomicroscopy for Gastric Intestinal Metaplasia Diagnosis
Magnified intelligence chromoendoscopy (FICE) plus probe-based confocal laser endomicroscopy (pCLE) for Gastric Intestinal Metaplasia (GIM) diagnosis: a feasibility trial Research Question: Is confocal endomicroscope feasible to…
- Trial name
- NCT01489397
- Testing
- Confocol laser endomicroscopy
- Where
- Thailand
- Volunteers
- 45 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Lower Gastrointestinal Disorders
Validation of Clinical Efficacy and Development of New Diagnostic Algorithm of Probe-based Confocal Laser Endomicroscopy in Patients With Lower Gastrointestinal Disorder
The aims of this research are to validate and develop of therapeutic strategies for patients with colorectal lesions in real time through pCLE(probe-based confocal laser endomicroscopy).
- Trial name
- NCT02091895
- Testing
- probe-based confocal laser endomicroscopy
- Where
- South Korea
- Volunteers
- 311 people
- Sponsor
- Yonsei University
Low Grade Intraepithelial Neoplasia, High Grade Intraepithelial Neoplasia
Comparison of pCLE and EB in Gastric Lesion Diagnosis
This is a prospective multicenter comparative study, aiming to compare probe-based confocal laser endomicroscopy (pCLE) and endoscopic biopsies in the diagnosis of the whole specific gastric lesion especially for distinguishing…
- Conditions
- Low Grade Intraepithelial Neoplasia, High Grade Intraepithelial Neoplasia, Early Gastric Cancer, Gastric Intraepithelial Neoplasia
- Trial name
- NCT06389448
- Testing
- pCLE-gastr
- Where
- China
- Volunteers
- 366 people
- Sponsor
- Huazhong University of Science and Technology
Pancreatic Cysts
Confocal Endomicroscopy of Pancreatic InVivo
Confocal laser endomicroscopy (CLE) is a novel and highly promising imaging method for that allows in vivo imaging of the mucosal layer at resolution of approximately 1 micron.
- Trial name
- NCT01035008
- Testing
- Endoscopic Ultrasound (EUS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Interstitial Lung Disease (ILD)
Confocal Laser Endomicroscopy Guided Cryobiopsy in the Diagnosis of Interstitial Lung Disease
This prospective, single-center, randomized controlled trial compares pCLE-guided TBLC with conventional TBLC in patients with suspected interstitial lung disease.
- Trial name
- NCT06741826
- Testing
- pCLE-guided transbronchial lung cryobiopsy, Fluoroscopy-guided transbronchial lung cryobiopsy
- Where
- China
- Volunteers
- 430 people
- Sponsor
- China-Japan Friendship Hospital
Colon Polyps, Adenomatous Polyps
Prospective Study for Evaluating Colon Polyp Histology With in Vivo Probe Based Confocal Laser Endomicroscopy
Chromoendoscopy (that involves spraying of dyes over the colonic mucosa) combined with magnification has been utilized for polyp histology identification.
- Conditions
- Colon Polyps, Adenomatous Polyps, Colon Cancer
- Trial name
- NCT01214031
- Testing
- Confocal laser endomicroscopy (CLE)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Midwest Biomedical Research