Clinical trials: Probes
Uterine Myoma
Radio Frequency Ablation (RFA STUDY )
The aim of this study is to investigate the safety and feasibility of a radiofrequency (RF) system employing RFITT (CelonProSurge) probes for the ablative treatment of uterine fibroids.
- Trial name
- RFA (NCT02631278)
- Testing
- Intraoperative radiofrequency ablation
- Where
- 2 sites in Italy
- Volunteers
- 10 people
- Sponsor
- Catholic University of the Sacred Heart
Skin Laxity, Skin Tightening
Effects of QUANTUM Probe for Skin Rejuvenation and Subdermal Retraction in Patients Undergoing High-Definition Liposculpture
This prospective study aims to evaluate the safety and effectiveness of Quantum, a fully internal bipolar radiofrequency probe, for the treatment of prominent skin laxity, providing patients with a more toned and youthful…
- Conditions
- Skin Laxity, Skin Tightening, Body Contouring Surgery, Skin Elasticity
- Trial name
- Quantum001 (NCT06958978)
- Testing
- Quantum RF
- Where
- Colombia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Prostate Cancer
Imaging Characteristics of Different ⁶⁸Ga-PSMA Probes in Prostate Cancer
This study aims to evaluate the imaging characteristics of [⁶⁸Ga]Ga-GS24-B2-250-T Injection (abbreviated as ⁶⁸Ga-GS24-B2-250-T), [⁶⁸Ga]Ga-GS24-B2-268-T Injection (abbreviated as ⁶⁸Ga-GS24-B2-268-T), [⁶⁸Ga]Ga-GS24-B2-237-T…
- Trial name
- NCT07365397
- Testing
- 68Ga-GS24-B2-268-T, 68Ga-GS24-B2-250-T, 68Ga-GS24-B2-237-T
- Volunteers
- 9 people
- Sponsor
- Shanghai Zhongshan Hospital
Gastric Cancer, Intestinal Metaplasia
New Classification of Stomach Using Probe-based Confocal Laser Endomicroscopy
The aim of the present study was to propose a new pCLE classification of gastric pit patterns and vessel architecture, and to assess the accuracy and interobserver agreement of this new pCLE classification system in the stomach.
- Conditions
- Gastric Cancer, Intestinal Metaplasia, Atrophic Gastritis, Inflammation
- Trial name
- NCT01896310
- Testing
- probe-based confocal laser endomicroscopy
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Shandong University
Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT)
Cancer Venous Thromboembolism (VTE)
The primary objective is to demonstrate the non-inferiority of edoxaban (preceded by a short course of LMWH) compared with dalteparin for the prevention of the combined outcome of recurrent venous thromboembolism (VTE) or major…
- Conditions
- Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Cancer
- Trial name
- NCT02073682
- Testing
- Edoxaban, Dalteparin, Low molecular weight heparin
- Where
- 9 sites in United States, Belgium and 4 more
- Volunteers
- 1,046 people
- Sponsor
- Daiichi Sankyo
Major Depressive Disorder
Neuro-Cardiac-Guided Transcranial Magnetic Stimulation: Replication and Dose-response.
Autonomic regulation is disturbed in patients with major depressive disorder (MDD), indicated by a higher heart rate (HR) and lower heart rate variability (HRV).
- Trial name
- NCT03652597
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Utrecht University
Cigarette Smoking, Tobacco Smoking
Mindfulness Training for Smoking Cessation
The purpose of this study is to assess the effects of mindfulness training (MT) compared to standard Smoking Cessation Therapy (SCT) on smoking cessation and stress provocation in individuals trying to quit smoking.
- Conditions
- Cigarette Smoking, Tobacco Smoking, Nicotine Dependence, Smoking Cessation
- Trial name
- NCT01144689
- Testing
- Mindfulness Training, Smoking Cessation Therapy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Yale University
Breast Cancer
Clinical Evaluation of Opto-Acoustic Image Quality With the Gen1B Duplex Probe in Breast Applications
Comparative Evaluation of Gen1B (OA-16-1S) duplex OA/US probe versus Gen1 (OA-16-1) duplex OA/US probe in Healthy Subjects
- Trial name
- NCT03845907
- Testing
- Gen 1B, Gen 1
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Seno Medical Instruments Inc.
Healthy
To Determine the Effect of CYP Induction Following Administration of Nirogacestat in Healthy Adult Male Participants
This study will evaluate the effects of nirogacestat 100 mg twice daily (BID) on the pharmacokinetics (PK) of a cytochrome P450 (CYP) cocktail.
- Trial name
- NCT07259330
- Testing
- Nirogacestat, Nirogacestat and Cocktail of CYP Specific Probe Substrates
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany
Seasonal Rhinitis and/or Rhinoconjunctivitis, Birch Pollen Allergy
SUBLIVAC® Birch PROBE Study
Objective of the study is to show, on an exploratory basis, that treatment with SUBLIVAC Birch is also effective compared to treatment with Staloral Birch by means of reduction in allergic symptoms during nasal provocation in…
- Trial name
- NCT00932607
- Testing
- sublingual immunotherapy
- Where
- Germany
- Volunteers
- 74 people
- Sponsor
- HAL Allergy
Social Anxiety Disorder
Attention Bias Modification Treatment (ABMT) and Cognitive-Behavioral Group Therapy (CBGT) in Social Anxiety Disorder
This RCT examines the effectiveness of Attention Bias Modification Treatment (ABMT) as an augment to Cognitive-Behavioral Group Treatment (CBGT) for Social Anxiety Disorder (SAD) in adults. It is expected that ABMT vs.
- Trial name
- ABMT+CBGT (NCT02338453)
- Testing
- Active Attention Bias Modification Treatment
- Where
- 2 sites in Israel
- Volunteers
- 50 people
- Sponsor
- Yair Bar-Haim
Age-related Skin Changes
Evaluation of Age-related Skin Changes Using Clinical Probe Measurements and Imaging Modalities in Chinese Subjects
Evaluation of age-related skin changes using clinical probe measurements and imaging modalities in Chinese subjects.
- Trial name
- NCT04655300
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Allergan
HIV Infections, AIDS
Safety and Durability ofTenofovir and a Cell Cycle Agent for Viral Suppression
Study Hypothesis Evaluation of the durability of the combination Tenofovir and Hydroxyurea to maintain viral suppression below 50 copies/ml in volunteers who have achieved viral suppression on a standard HAART regimen.
- Trial name
- HADIT (NCT00344981)
- Testing
- Tenofovir, Hydroxyurea
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Maryland, Baltimore
In-plane Ultrasound-guided Regional Anesthesia Performance
Trial on the Effects of Ultrasound Probe Position on Ultrasound-guided Nerve Blocks
Ultrasound has been used to guide a needle to inject local anesthetics around nerves. This is usually done in the same plane as the ultrasound beam in America and is known as an in-plane technique.
- Trial name
- NCT01690156
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Prostate Cancer
Ex-vivo Investigation of Beta Probe for Prostate Cancer Resection and Evaluation of PSMA-PET for Diagnosis of Intraprostatic Lesions
68Ga-PSMA is a radiopharmaceutical used with PET imaging for the detection of prostate cancer under a compassionate IND in patients who have presented with biochemical failure.
- Trial name
- NCT03213951
- Testing
- Experimental beta probe, PSMA-PET
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Indiana University
Acute Myocardial Infarction (AMI)
POCT Detection for Blood Concentration of Tirofiban in Acute Myocardial Infarction Based on Azo-POP Probe.
The goal of this observational study is to monitor blood drug concentration during the use of tirofiban, predict the occurrence of intraoperative and postoperative complications related to interventional therapy, and evaluate the…
- Trial name
- NCT06836531
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Ningbo University
Chlamydia Infections, Gonorrhea
Prospective Collection of Female Specimens for Testing With Gen-Probe APTIMA (Registered Trademark) Assays
The objective of this study is to obtain female first-catch urine, vaginal, cervical and endocervical swabs for testing with multiple APTIMA Assays on the Gen-Probe PANTHER® and TIGRIS® Systems.
- Conditions
- Chlamydia Infections, Gonorrhea, Trichomonas Infections
- Trial name
- NCT01728103
- Testing
- APTIMA® Trichomonas vaginalis & APTIMA® COMBO 2® Assays
- Where
- 14 sites in United States
- Volunteers
- 1,336 people, healthy volunteers welcome
- Sponsor
- Gen-Probe, Incorporated
Cerebral Stroke
Super-Resolution Ultrasound of the Brain in 3D
The goal of this proof of concept study is to determine if the visualization of the middle cerebral artery and its perforators, through 3D transtemporal ultrasound imaging, is possible thanks to an off-line analysis by 3D…
- Trial name
- ESRC3D (NCT06133179)
- Testing
- Transtemporal ultrasound with contrast product (Sonovue)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Gynecologic Cancer, Venous Thromboembolism
Oral Apixaban (Eliquis) Versus Enoxaparin (Lovenox) for Thromboprophylaxis in Women With Suspected Pelvic Malignancy
The study will evaluate the incidence of major bleeding (including clinically relevant non-major (CRNM) bleeding) events in women undergoing surgery for gynecologic cancer with apixaban 2.5 mg twice a day (BID) compared to…
- Trial name
- NCT02366871
- Testing
- Oral apixaban, Subcutaneous enoxaparin
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Colorado, Denver
Healthy Volunteers
A Phase 1 Study to Assess the Effect of ABBV-722 on Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin Drug Levels in Healthy Adults.
The objective of this study is to assess the effect of repeated doses of ABBV-722 on the single dose pharmacokinetics (PK) of Midazolam, Digoxin, Pitavastatin, Metformin, and Sitagliptin
- Trial name
- NCT07567781
- Testing
- ABBV-722, Midazolam, Metformin
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AbbVie