Clinical trials: Probiotic Supplement
Healthy Adults
Prospective Tolerability Assessment of a Probiotic Dietary Supplement
The dietary supplement being investigated is a formula containing a combination of eight probiotic strains. The combination formula was developed to support general gastrointestinal and immune health.
- Trial name
- NCT04044144
- Testing
- Probiotic Dietary Supplement
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Metagenics, Inc.
Healthy
A Study of a Probiotic Food Supplement Containing B. Infantis (EVC001) in Healthy Breastfed Infants at Risk of Developing Atopic Dermatitis
The purpose of this study is to assess the effect of B. infantis (EVC001) versus placebo supplementation, in healthy breastfed infants at risk of developing atopic dermatitis (AD), on cumulative incidence of physician-diagnosed…
- Trial name
- NCT04662619
- Testing
- B. infantis
- Where
- Finland
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Consumer Inc. (J&JCI)
Infantile Colic
Lactobacillus Reuteri Supplementation in the Treatment of Infantile Colic
The purpose of this study is to evaluate the efficacy of the oral administration of Lactobacillus reuteri in treating infantile colic as defined by the Rome III criteria.
- Trial name
- PROBIOC (NCT01887444)
- Testing
- Lactobacillus reuteri DSM17938 probiotic
- Where
- France
- Sponsor
- BioGaia AB
Intestinal C. Difficile
Probiotic Intervention With Elderly Subjects
The study objective is to evaluate the effect of probiotic on faecal Clostridium difficile levels of elderly subjects.
- Trial name
- NCT01475942
- Testing
- Probiotic
- Where
- Finland
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Danisco
Obesity, Hyperglycemia
The Effect of a Bifidobacterium and Polydextrose on Body Fat Mass
Obesity is a major problem worldwide, and it is related to abnormalities in glucose and lipid metabolism. The purpose of this study is to investigate the effect of a dietary supplement containing probiotic (Bifidobacterium…
- Conditions
- Obesity, Hyperglycemia, Insulin Resistance
- Trial name
- MetSProb (NCT01978691)
- Testing
- Bifidobacterium animalis ssp. lactis 420, Polydextrose
- Where
- 4 sites in Finland
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Danisco
Clostridium Difficile Infection Recurrence
Bacillus Velezensis DSM 33864 for Reduction of the Risk of Recurrent Clostridioides Difficile Infections
The purpose of this study is to determine whether a single strain capsulated probiotic, when used after standard C. difficile antibiotic therapy, is effective in reducing the risk of infection recurrence mediated by a decrease in…
- Trial name
- NCT05606159
- Testing
- Bacillus velezensis DSM 33864
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Novozymes A/S
Infertility, Female, Polycystic Ovary Syndrome
Antioxidant Supplement Associated With Oral Probiotics in Patients With PCOS in IVF
The aim of the study is to study the effect of an antioxidant food supplement associated with probiotics on the oocyte quality response, oxidative stress and microbiota function in an in vitro fertilization cycle in patients with…
- Trial name
- NCT04670393
- Testing
- FertyBiotic Woman Plus
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Fertypharm
Overweight, Obesity Grade I
Clinical Trial to Evaluate the Effect of a Probiotic Product on Weight
The study of the intestinal microbiota and its relationship with health and disease, as well as the use of probiotics as effective alternative treatments to improve people's well-being is a field of growing research in recent…
- Trial name
- NCT06815926
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Bioithas SL
Functional Dyspepsia
Probiotic and Ginger Supplement for Symptoms and Quality of Life in Functional Dyspepsia (SUBTILE)
Functional dyspepsia (FD) is a frequent functional gastrointestinal disorder characterized by bothersome postprandial fullness, early satiety, epigastric pain, or burning, in the absence of any structural or metabolic cause.
- Trial name
- SUBTILE (NCT07212907)
- Testing
- Symbiosys® Stomalex (commercial name)
- Where
- France
- Volunteers
- 198 people
- Sponsor
- Biocodex
Healthy Participants
Impact of Supplementation of Probiotics and Grape Marc on Psychological Well-being of Healthy Adults
An open-label, baseline-controlled (pre-post) pilot study to assess the maintenance and/or improvement of both physical and mental well-being in subjects who daily consume either a food supplement or a functional food containing…
- Trial name
- Rescue-bio (NCT07265934)
- Testing
- Probiotic bars, Probiotic capsules
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Synbiotec Srl
Environmental Exposure, PFAS Exposure
Effect of a Dietary Supplement Versus Placebo on Serum PFAS Levels in Male Firefighters
This study is designed to evaluate the effect of a probiotic dietary supplement containing Streptococcus salivarius on serum PFAS levels in male firefighters with documented occupational PFAS exposure, following twice-daily use…
- Trial name
- AFCRO202 (NCT07846371)
- Testing
- Streptococcus salivarius 46-SL1
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Cambiotics ApS
Microbiota, Constipation
A Probiotic Blend Reduces Gastrointestinal Symptoms and Positively Impacts Microbiota Modulation in a Randomized Study
This randomized, placebo-controlled, double-blind study will determine the effect of daily supplementation with a probiotic blend in 60 apparently healthy men and women recruited at a single investigational center in Northeast…
- Conditions
- Microbiota, Constipation, Candida
- Trial name
- NCT05614726
- Testing
- 575mg [30 billion colony forming units] probiotic blend of Bifidobacterium breve, Lactobacillus acidophilus, Lacticaseibacillus rhamnosus, Saccharomyces boulardii, and alpha amylase
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The Center for Applied Health Sciences, LLC
Healthy
Natural Product System and Lifestyle Modification
The goal of this clinical trial is to learn whether four dietary supplements and lifestyle changes can affect gene expression and blood markers in healthy volunteers. The main questions it aims to answer are: 1.
- Trial name
- NCT06931977
- Testing
- Supplement system + copaiba softgels
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- dōTERRA International
COVID-19
Monitoring the Efficacy of a Probiotic Dietary Supplement SmartProbio C in Patients With Severe COVID-19 Infection
The aim of the study is to test the efficacy of the probiotic SmartProbio C in patients with a severe course of COVID-19 infection. Patients were randomly divided into two arms between the probiotic group and the placebo group.
- Trial name
- NCT05474144
- Testing
- SmartProbio C
- Where
- 2 sites in Czechia
- Volunteers
- 83 people
- Sponsor
- Medi Pharma Vision
Signs and Symptoms, Digestive, Dyspepsia
Evaluation of the Effect of a Probiotic Supplement Upon Gastrointestinal Function
The purpose of this pilot study is to evaluate whether a probiotic supplement improves gastrointestinal (GI) function.
- Trial name
- NCT02928484
- Testing
- Probiotic mix CBP-004019/C
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Biopolis S.L.
Vaginal Microbiota, Microbiota
Effect of Hifas Intima Oral on Vaginal Microbiota in Healthy Women
The goal of this clinical trial was to learn whether the vaginal microbiota changed after healthy women aged 18 to 45 years took Hifas Intima, an oral food supplement, for 3 months.
- Conditions
- Vaginal Microbiota, Microbiota, Vaginal Microbiome
- Trial name
- NCT07715058
- Testing
- Hifas INTIMA Oral
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hifas da Terra S.L.
Functional Constipation
Effect of an 8-week Bifidobacterium Lactis HN019 Supplementation on Functional Constipation
This prospective, two-arm (parallel groups), double-blind, randomized, placebo-controlled, multi-center clinical trial will investigate the effects of an 8-week Bifidobacterium lactis HN019 supplementation on stool frequency and…
- Trial name
- BifidoDigest (NCT04231162)
- Testing
- Active product, Control product
- Where
- 4 sites in France
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Danisco
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
Effect of Probiotics in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a neurological disease. Currently there is no effective treatment for ME/CFS due to unclear etiology of the disease.
- Trial name
- NCT04741841
- Testing
- GutMagnific™ H., GutMagnific™ L.
- Where
- Sweden
- Volunteers
- 74 people
- Sponsor
- ImmuneBiotech Medical Sweden AB
IBS, Constipation Predominant
The Beneficial Effects on the Intestinal Function of a Food Supplement Based on an Extract of Green Tea and a Pool of Probiotics in Subjects With Irritable Bowel Syndrome With Predominance of Constipation
The study will aim to evaluate the effectiveness of the use of a food supplement, based on a green tea extract (Camellia sinensis (L.) Kuntze - folium) and a pool of probiotics (L. plantarum, L. rhamnosus and B. animalis subsp.
- Trial name
- NCT07094035
- Testing
- food supplement based on a mixture of green tea extract and a pool of probiotics.
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Adamas Biotech S.r.l.
Recurrent Urinary Tract Infections
Probiotic Supplement for Recurrent UTIs in Healthy Women (L. Plantarum, L. Rhamnosus, B. Lactis)
This randomized, double-blind, placebo-controlled trial will evaluate the efficacy of a probiotic food supplement containing Lactiplantibacillus plantarum PBS067, Lacticaseibacillus rhamnosus LRH020, and Bifidobacterium animalis…
- Trial name
- BIO-RUTI-26 (NCT07884929)
- Testing
- Dietary Supplement containing probiotics
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Synbalance S.r.l.