Clinical trials: Probiotic Supplement
Gut-brain Axis, Dietary Changes
The Gut Brain Axis, Effect of Dietary Changes and Probiotics Supplement on Depression Symptoms .
To investigate the effects of a high-fiber diet and probiotic supplementation on depression symptoms in adult individuals.
- Conditions
- Gut-brain Axis, Dietary Changes, Probiotics Supplement, Depression Symptoms
- Trial name
- NCT06639646
- Testing
- Probiotics supplements, Health diet
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Kasr El Aini Hospital
Gastrointestinal Discomfort, Bloating
Multi-strain Probiotic Supplement for Digestive Comfort and Well-being in Healthy Women
This study looks at whether a daily probiotic supplement can help improve mild-to-moderate stomach and digestive symptoms, such as gas and bloating, in women who also experience symptoms commonly associated with hormonal…
- Trial name
- NCT07831317
- Testing
- Active: Multi-strain probiotic dietary supplement
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Daily Nouri
Obesity, Gastric Bypass
Impact of a Specific Micronutrient-probiotic-supplement on Fatty Liver of Patients After Mini-Gastric Bypass Surgery
Aim of this prospective randomized intervention study is to evaluate the effect of a dietary intervention with a specific micronutrient-probiotic-combination for 12 weeks on fatty liver and cardiometabolic status in obese…
- Conditions
- Obesity, Gastric Bypass, NAFLD
- Trial name
- FMG-01 (NCT03585413)
- Testing
- Micronutrient-probiotic-combination
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Bonn Education Association for Dietetics r.A., Cologne, Germany
Pregnancy Related
Evaluation of the Effect of FertyBiotic Pregnancy in the Metabolic Profile in Pregnant Women
The aim of this study is determine the effect of a food supplement with probiotics on metabolic profile and weight gain in pregnant women.
- Trial name
- NCT04935840
- Testing
- FertyBiotic Pregnancy, Control
- Where
- 2 sites in Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Fertypharm
Crohn's Disease, Inflammatory Bowel Disease
A Randomized Controlled Trial of VSL#3 for the Prevention of Endoscopic Recurrence Following Surgery for Crohn's Disease.
This randomized placebo-controlled double-blind, multi-centre trial will determine the efficacy of the probiotic VSL#3 in the prevention of Crohn's disease development following surgical resection and re-anastomosis.
- Trial name
- NCT00175292
- Testing
- Probiotic - VSL#3
- Where
- 17 sites in Canada
- Volunteers
- 120 people
- Sponsor
- University of Alberta
Diabete Type 1, Diabete Type 2
Effects of LP-LDL® on Lipid Metabolism, Glycemic Control, Inflammatory Markers, and Cognitive Function in Individuals With Prediabetes and Diabetes Mellitus
This randomized, double-blind, placebo-controlled clinical trial investigates the effects of the probiotic LP-LDL® (Lactobacillus plantarum ECGC 13110402) on lipid metabolism, glycemic control, inflammatory biomarkers, and…
- Conditions
- Diabete Type 1, Diabete Type 2, Prediabetes
- Trial name
- NCT07373392
- Testing
- Lactobacillus plantarum ECGC 13110402
- Where
- 2 sites in Denmark
- Volunteers
- 210 people
- Sponsor
- Aalborg University
Reproductive Techniques, Assisted
Effect of a Multivitamin Supplement With Probiotic (Seidivid Ferty4®) on Oocyte Retrieval and Quality
This study evaluates the effect of pretreatment with a multivitamin supplement with probiotics (Seidivid Ferty4®) on oocyte retrieval in normo-responder patients undergoing controlled ovarian hyperstimulation (COH) for oocyte…
- Trial name
- OvoVid (NCT05473039)
- Testing
- Seidivid Ferty4
- Where
- Spain
- Volunteers
- 196 people
- Sponsor
- SEID S.A.
Depression, Depression Disorder
GynMDD Add-On to Supportive Psychotherapy in Mild to Moderate Depression
The goal of this clinical trial is to learn whether the dietary supplement GynMDD, when taken as an add-on to supportive psychotherapy, can improve symptoms of mild to moderate depression in adults aged 18 to 65.
- Conditions
- Depression, Depression Disorder, Depression in Adults
- Trial name
- SWING (NCT07416747)
- Testing
- GynMDD
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Fondation FondaMental
Total Parenteral Nutrition, Necrotizing Enterocolitis of Newborn
Probiotics/TPN in the NICU
The purpose of this study is to evaluate the effect of probiotic administration on TPN dependence in infants < 32 weeks GA and BW 1500 grams or less in the Banner - University Medical Center Phoenix and Banner Children's at…
- Trial name
- NCT04977817
- Testing
- Similac Probiotic Tri-Blend
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Pediatrix
NASH - Nonalcoholic Steatohepatitis
Interest in "Combo" (a Combination of Dietary Supplements Including Probiotics) in NASH Improvement
The aim of this bicentre, prospective, placebo-controlled, double-blind, randomized, interventional study is to assess for the first time the effects of a Combo with probiotics and dietary supplements compared to placebo for…
- Trial name
- ICAN (NCT04781933)
- Testing
- Treatment with Combo
- Where
- 2 sites in France
- Volunteers
- 60 people
- Sponsor
- Mativa-Tech SA
Functional Gastrointestinal Disorders, Functional Abdominal Pain
Effect of 35624® Alflorex® in Functional Gastrointestinal Disorders (FGIDs) in Children.
The aim of this study is to evaluate the effect of supplementation with Bifidobacterium longum 35624® Alflorex® on frequency and severity of symptoms of abdominal pain using an adapted Irritable Bowel Symptom Severity Scoring…
- Trial name
- NCT04922476
- Testing
- Alflorex®
- Where
- Chile
- Volunteers
- 65 people
- Sponsor
- PrecisionBiotics Group Ltd.
Attention Deficit Hyperactivity Disorder (ADHD)
Probiotic Supplement as Treatment for Students With ADHD
Subjects will answer the following questionnaire and tests: Symptom severity and improvement will be measured using ADHA Rating scale IV (ADHD RS) Demographic Questionnaire - composed by the researchers Family Eating Habits…
- Trial name
- NCT02908802
- Testing
- Probiotic
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Tel Hai College
Vitamin D Deficiency
Evaluation Of The Effect Of L. Casei DG® On Vitamin D Absorption In Patients Under Vitamin D Supplementation.
Vitamin D deficiency is one of the most underdiagnosed and undertreated medical condition worldwide . The microbiome and vitamin D deeply influence each other and the immune system in many different ways.
- Trial name
- NCT05394207
- Testing
- L. casei DG® (Lactobacillus paracasei CNCM I-1572)
- Where
- United Arab Emirates
- Volunteers
- 46 people
- Sponsor
- SOFAR S.p.A.
Healthy
Safety of Lactobacillus Rhamnosus GG ATCC 53103 (LGG) in Healthy Volunteers
This study is a single site, Phase I, masked, randomized study to evaluate the safety and tolerability of twice daily dosing of LGG (Lactobacillus GG ATCC 53103) in normal healthy adult volunteers.
- Trial name
- NCT00934453
- Testing
- Lactobacillus rhamnosus GG ATCC 53103
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Chronic Obstructive Pulmonary Disease, Non-cystic Fibrosis Bronchiectasis
A Study to Evaluate the Effect of Probiotic Supplement on Quality of Life
This study aims to evaluate the impact of a specific oral probiotic blend on the quality of life of adults with respiratory conditions.
- Trial name
- NCT05523180
- Testing
- Probiotic
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- ResBiotic Nutrition, Inc.
Healthy Adult Subjects
Dietary Supplement With and Without a Probiotic
Complex oligosaccharides can alter the gut microbiome by aiding in the growth of certain organisms, and possibly, inhibiting others. The synergy with a probiotic may enhance gastrointestinal colonization.
- Trial name
- NCT04433208
- Testing
- Complex oligosaccharide, Probiotic, PPI
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Prolacta Bioscience
Dental Caries in Children
Prevention of Recurrent Caries With Lactobacilli PRECAL
The aim of this study was to compare the effect of drops containing probiotic bacteria (Lactobacillus reuteri 17938, Lactobacillus reuteri PTA 5289, Biogaia AB, Sweden) on the incidence of dental caries with placebo drops in…
- Trial name
- NCT04929340
- Testing
- Probiotic bacteria
- Where
- 3 sites in Sweden
- Volunteers
- 70 people
- Sponsor
- Umeå University
Pregnancy Related
Correlating Probiotic Dietary Supplements During Pregnancy With Maternal Microbiome Profiles
The overarching goal of this project is to compare the microbiome profiles of healthy pregnant women, both before and after the introduction of a probiotic supplement into the maternal diet.
- Trial name
- NCT03611647
- Testing
- Probiotic
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Schizophrenia, Schizoaffective Disorder
Double-Blind Trial of a Probiotic Supplement to Reduce the Symptoms of Schizophrenia
The investigators intend to explore the hypothesis that symptoms of schizophrenia may be reduced by the administration of a probiotic supplement when used in addition to standard antipsychotic medications.
- Trial name
- NCT01242371
- Testing
- Probiotic Supplement
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Sheppard Pratt Health System
Menopause
The Effects of a Novel Probiotic Supplement on Menopausal Symptoms and Bone Health
This Phase II study is designed to evaluate the potential effects of a novel probiotic supplement on the severity of global menopause symptoms (e.g., psychological, somatic, urogenital symptoms) and on bone health in…
- Trial name
- MPS (NCT04001088)
- Testing
- Probiotic
- Where
- 5 sites in United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Lallemand Health Solutions