Clinical trials: Probiotic Therapy
Crohn's Disease
Treatment With Lactobacillus Rhamnosus and Lactobacillus Acidophilus for Patients With Active Colonic Crohn's Disease.
The purpose of this study is to determine whether a probiotic containing Lactobacillus Acidophilus and Lactobacillus Rhamnosus is effective as treatment for patients with active colonic Crohn's disease
- Trial name
- NCT00374374
- Testing
- Administration of probiotic
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Obesity, Insulin Resistance
Synbiotic Therapy on Intestinal Microbiota and Insulin Resistance in Obesity
Background : There is a plausible relationship between microbial gut and insulin resistance. Intervention to prevent insulin resistance by modifying the microbial gut has been proposed but limited studies demonstrates the…
- Trial name
- NCT04642482
- Testing
- Synbiotic (Rillus)
- Where
- Indonesia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Recurrent UTIs, Catheter-Related Infections
Novel Probiotic Treatment for Prevention of Recurrent UTIs in Children
Background: Urinary tract infections (UTIs) are a common and costly cause of doctor visits for children. Frequent UTIs trigger kidney damage that leads to serious diseases like high blood pressure, pregnancy complications, and…
- Trial name
- Nissle 1917 (NCT01696227)
- Testing
- Nissle 1917
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Helicobacter Pylori Infection
Study the Effect of Probiotics Combined With Bismuth Quadruple Rescue Therapy on H Pylori Infective Patients
Retrospectivly follow-up the outpatients for H pylori eradication failures more than 2 times in the digestive department of Changhai hospital from 2015-2017,analyse the eradication rates and adverse effects of the therapy with…
- Trial name
- NCT03297242
- Volunteers
- 30 people
- Sponsor
- Changhai Hospital
Inflammation
Effect of Probiotic Supplementation on Immune Function in Healthy Infants
The purpose of this study is to understand how a probiotic might change the immune response of healthy infants.
- Trial name
- ProBoost (NCT01542320)
- Testing
- Lactobacillus reuteri DSM 17938
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Emory University
Rectal Cancer
Action of Synbiotics on Irradiated GI Mucosa in Rectal Cancer Treatment
The aim of this study is to investigate how bacteria and fibre interact with the epithelial cells of the gastrointestinal mucosa to reduce inflammation and to diminish tissue damage caused by radiation therapy to patients…
- Trial name
- FIPIREX (NCT03420443)
- Testing
- Oat bran, Oat bran and blueberry husks, No oral supplementation
- Volunteers
- 30 people
- Sponsor
- Region Skane
Schizophrenia and Related Disorders, Diet Habit
Efficacy of Prebiotic and Probiotic Dietary Modulation in Schizophrenic Disorders
The microbiota plays a vital role in the two-way communication between the gastrointestinal tract and the central nervous system (CNS), articulated as the microbiota-intestine-brain axis.
- Trial name
- NCT04366401
- Testing
- Conventional Dietary Advice, Prebiotic/Probiotic Dietary Modulation
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- Universidad de Córdoba
Respiratory Tract Infections (RTI), Mucosal Immunity
Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before and After a Race
This study aims to evaluate whether a fermented milk drink containing the probiotic strain Lacticaseibacillus paracasei strain Shirota (LCS), commonly found in Yakult®, can help reduce upper respiratory symptoms in triathletes…
- Conditions
- Respiratory Tract Infections (RTI), Mucosal Immunity, Systemic Inflammation, Depressive Disorder
- Trial name
- NCT06970964
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Fibromyalgia
The Effect of Probiotic and Prebiotic Use on Fibromyalgia Syndrome
The aim of the present study is to determine the effectiveness of probiotic and prebiotic treatments in patients with fibromyalgia syndrome.
- Trial name
- NCT04607278
- Testing
- Probiotic, Prebiotic
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Ankara University
Diarrhea Infectious
Probiotics Administration Via Colonoscopic Spray and Oral Administration in CDAD Patients
Clostridioides difficile (C. difficile) colitis is a common hospital-acquired disease, which increases hospitalization length and the mortality rate. Moreover, refractory or recurrent C. difficile colitis is an emerging disease.
- Trial name
- CDAD (NCT05770726)
- Testing
- Probiotics administration
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Drug Resistance, Bacterial, Antimicrobial Drug Resistance
Comparison of Three Interventions for Antibiotic-Resistant Bacteria (ARB) Decolonization From the Gastrointestinal Tract
The aim of this research experiment is to evaluate the effectiveness of fecal microbiota transplantation (FMT) preceded by antibiotic pre-treatment versus probiotic therapy and a standard-of-care equivalent diet designed to…
- Trial name
- STOP-ARB3 (NCT07094984)
- Testing
- Fecal microbiota transplantation (FMT), Probiotic Therapy, Gut Microbiota Boosting Diet
- Where
- Poland
- Volunteers
- 360 people
- Sponsor
- Medical University of Warsaw
Overactive Bladder
Optimizing Overactive Bladder Treatment
Purpose: This is a pilot randomized double-blind placebo controlled trial of anticholinergic or beta-3 agonist medication with or without concomitant probiotic therapy in women initiating medication therapy for overactive bladder…
- Trial name
- OPS (NCT03904407)
- Testing
- Lactobacillus Probiotic Capsule
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- University of North Carolina, Chapel Hill
Periodontal Diseases, Pregnancy Related
Adjunctive Periodontal Treatment With Coenzyme Q10 in Association With Probiotics for Pregnant Women
The aim of the study is to assess if probiotic supplementation can be effective in reducing periodontal clinical parameters in a 6-month study on pregnant patients.
- Trial name
- NCT06308497
- Testing
- Probiotic Treatment, Standard Treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Upper Respiratory Tract Infections, Pharyngitis
Efficacy and Safety of L. Plantarum and P. Acidilactici in Children With Upper Respiratory Tract Infections
Randomized, placebo-controlled trial to evaluate the coadjuvant effect of a combination of L. plantarum and P. acidilactici probiotic strains, taken twice daily, in children 6 months to 5 years-old with upper respiratory tract…
- Conditions
- Upper Respiratory Tract Infections, Pharyngitis, Tonsillitis
- Trial name
- NCT05279534
- Testing
- Probiotic
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- AB Biotics, SA
Rosacea, Rosacea Papular Type
Clinical Trial to Evaluate the Effect of a Probiotic Mixture on the Rosacea Evolution
The clinical trial has a randomized, double-blind, placebo-controlled design, in which the aim is to evaluate the effect of a probiotic mix, with a 12-week treatment, on the evolution of rosacea.
- Conditions
- Rosacea, Rosacea Papular Type, Rosacea, Papulopustular
- Trial name
- NCT05815511
- Testing
- Probiotic mixture
- Where
- 3 sites in Spain
- Volunteers
- 70 people
- Sponsor
- Bionou Research, S.L.
Familial Mediterranean Fever (FMF )
The Effect of Probiotics on Response to Therapy and on Adverse Effect in Patients Treated With Colchicine for Familial Mediterranean Fever.
Colchicine is the drug of choice to treat patients with Familial Mediterranean Fever (FMF ), some of the patients treated with colchicine may suffer from gastrointestinal (GIT) adverse effect such as diarrhea and abdominal pain…
- Trial name
- NCT02021084
- Testing
- probiotic
- Sponsor
- Rambam Health Care Campus
Periodontitis Stage IV, Periodontitis
Microbiological Modulation Of The Oral-Gut Axis After Treatment With Or Without Systemic Use Of Probiotics In Patients With Periodontitis: A Randomized Controlled Clinical Study.
This study aims to evaluate whether the oral administration of probiotics, in combination with conventional periodontal treatment (deep cleaning of the tooth root surfaces), can improve oral health and influence the relationship…
- Trial name
- NCT07792902
- Testing
- Probiotics Bifidobacterium animalis subsp. lactis HN019
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Throat Pain
The Effectiveness of Probiotics for the Therapy of Acute Pharyngotonsillitis in Adult Patients
The addition of probiotics to the routine therapy of Acute Pharyngotonsillitis in adult patients may shorten the duration, and reduce the severity of the disease.
- Trial name
- NCT01679366
- Testing
- Probiotics
- Where
- Israel
- Volunteers
- 57 people
- Sponsor
- Ziv Hospital
Colic
Lactobacillus Reuteri DSM 17938 Versus Placebo in the Treatment of Infantile Colic
Infantile colic is a common medical condition which remains a frustrating problem for parents and health care providers with no clear treatment guidelines.
- Trial name
- NCT01541046
- Testing
- Biogaia L. reuteri DSM 17938
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- The Hospital for Sick Children
Chronic Rhinosinusitis
Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis
Chronic sinusitis is reported to be one of the most widespread disorders in the United States. It can be caused by a variety of reasons such as allergy, infection and/or defects in T-cells which help regulate immune function.
- Trial name
- NCT00396162
- Testing
- probiotic containing L.rhamnosus R0011 strain
- Volunteers
- 77 people
- Sponsor
- University of Michigan