Clinical trials: Probiotic Therapy
Fibromyalgia, Fibromyalgia Syndrome
PRL2019 in the Treatment of Juvenile Fibromyalgia
Juvenile Fibromyalgia Syndrome (JFS) is a chronic condition affecting children and adolescents, characterised by widespread musculoskeletal pain and a significant impact on daily life and quality of life.
- Trial name
- IGG-microbiota (NCT07738926)
- Testing
- Bifidobacterium adolescentis PRL2019
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Giannina Gaslini
Human Immunodeficiency Virus
Improving Prognosis in HIV Infection
The primary objective of this study is to assess the safety of probiotics in cART-treated immunologic non-responder (INR) patients with chronic HIV infection.
- Trial name
- NCT02640625
- Testing
- Probiotic compound
- Where
- Norway
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Colitis, IBD (Inflammatory Bowel Disease)
Evaluate the Efficacy and Safety of Probiotic 6600 as an Adjuvant Therapy for Colitis
This study was conducted in two phases. In Phase I, 40 UC participants, 40 CD participants, and 40 colitis participants were randomly assigned in a 1:1 ratio to the experimental group and the control group, respectively.
- Conditions
- Colitis, IBD (Inflammatory Bowel Disease), Probiotic Intervention
- Trial name
- NCT07047339
- Testing
- Probiotics 6600
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changhai Hospital
Inflammatory Bowel Disease
Research on the Use of Probiotics in the Prevention and Treatment of Inflammatory Bowel Disease
This study evaluates oral Lactobacillus reuteri as an adjunct therapy for 2 months. Endoscopic assessments will be performed at baseline and after 2 months of intervention to evaluate intestinal inflammation.
- Trial name
- NCT06781827
- Testing
- Probiotic
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Wecare Probiotics Co., Ltd.
Juvenile Idiopathic Arthritis
Probiotic Treatment in Juvenile Idiopathic Arthritis (JIA)
This study investigates the efficacy of probiotic VSL#3 as an add on standard care on the activity of the disease in patients with Juvenile Idiopathic Arthritis.
- Trial name
- PERMAJI (NCT03092427)
- Testing
- VSL#3
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity &Amp; Overweight
The Impact of Probiotics on Bariatric Treatment Outcomes
The planned study aims to assess whether probiotics improve the quality of life in patients during the early postoperative period following sleeve gastrectomy, and whether they influence the absorption of micro- and…
- Trial name
- PROBE (NCT07258732)
- Testing
- Probiotic, Diet
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Acute Gastroenteritis
Efficacy and Safety of Probiotics in the Treatment of Acute Gastroenteritis in Children
Primary Objective: o To assess the efficacy of the probiotics in reducing the duration of diarrhea in children suffering from acute gastroenteritis.
- Trial name
- SABINA (NCT03539913)
- Testing
- Probiotic : Saccharomyces boulardii, Probiotic : Bacillus clausii
- Where
- 8 sites in Argentina
- Volunteers
- 317 people
- Sponsor
- Biocodex
Treatment of Minor Aphthous Ulcers
Evaluation of Topical Probiotic Gel Versus Triamcinolone in Minor Recurrent Aphthous Ulcers
This study looks at a new way to treat minor recurrent aphthous ulcers. These ulcers are painful, round or oval sores that show up on the soft, non-chewing surfaces of the mouth (like the inside of the cheeks or lips).
- Trial name
- NCT07672730
- Testing
- Probiotic gel, Triamcinelone acetonide
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Cairo University
Antibiotic-Associated Diarrhea
Probiotics for Prevention of Antibiotic-associated Diarrhea
The purpose of this study is to evaluate if ingestion of a probiotic formula (Jarrow-Dophilus EPS)reduces incidence of diarrhea and improves the quality of life of patients receiving antibiotic therapy.
- Trial name
- NCT00641199
- Testing
- Jarro-Dophilus EPS probiotics
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- University of Saskatchewan
Insulin Resistance, Polycystic Ovary Syndrome
Lactobacillus Rhamnosus and PCOS Treatment
The effect of Lactobacillus rhamnosus supplementation on body weight, hyperandrogenism and insulin resistance in overweight and obesity women with Polycystic Ovary Syndrome will be analysed.
- Conditions
- Insulin Resistance, Polycystic Ovary Syndrome, Hyperandrogenism, Obesity
- Trial name
- ProjectPCOS (NCT03902301)
- Testing
- Lactobacillus group, Dietary group
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Poznan University of Life Sciences
Ultra-endurance Athletes With Gastrointestinal Symptoms
Effects of Probiotics and Nutritional Status on Exercise-Induced Symptoms, and Endurance Performance in Ultra-Endurance Athletes
Ultra-endurance athletes have been commonly endured extreme conditions during races and training sessions, resulting in exercise-associated clinical symptoms, including gastrointestinal symptoms, dehydration, and elevated…
- Trial name
- NCT04779281
- Testing
- Oral Rehydration Salts supplemented with L. Rhamnosus GG, Oral Rehydration Salts only
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Istanbul Medeniyet University
Asthma Patients
EFFECTIVENESS of PROBIOTICS in ADULTS with MODERATE to SEVERE PERSISTENT ASTHMA
The objective of this study is to compare the effectiveness of probiotic as an adjuvant to standard therapy versus standard therapy alone in adult with moderate to severe persistent asthma in terms of 1.
- Trial name
- NCT06657066
- Testing
- Beclomethasone 200mcg, salbutamol 100mcg , Beclomethasone 200 mcg/Formoterol 6 mcg, 250 mg of lyophilized saccharomyces boulardii, Control (Standard treatment)
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- King Edward Medical University
Obesity
Effects of Probiotics in Obese Children
The global obesity epidemic presents an unprecedented challenge to the public health worldwide. The factors associated with obesity are complex, and include health behaviors, such as eating habits and daily physical activity, and…
- Trial name
- Prob-esity (NCT01927107)
- Testing
- Probiotics mixture
- Volunteers
- 120 people
- Sponsor
- Eskisehir Osmangazi University
Indirect Hyperbilirubinemia
Efficacy of Bifidobacterium Animalis Subsp. Lactis in the Treatment of Indirect Hyperbilirubinemia in Term Neonates
This study aims to evaluate the effectiveness of adjunctive oral Bifidobacterium animalis subsp. lactis in term neonates with indirect hyperbilirubinemia receiving phototherapy.
- Trial name
- NCT07773012
- Testing
- Bifidobacterium animalis subsp. lactis, Standard Phototherapy
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Breast Cancer, Probiotic Therapy
Assessment of the Effect of Probiotic Supplementation on Proinflammatory Mechanisms Induced by Systemic Treatment in Women With Breast Cancer
The gut microbiota and its role in cancer treatment are currently the subject of intensive research. It has long been known that interactions between the microbiome and the host are responsible for the proper functioning of many…
- Trial name
- NCT07607548
- Testing
- Probiotic
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Obesity and Overweight, Obesity, Morbid
Impact of Nutritional Intervention With Probiotics and Prebiotics on Obesity.
Obesity is one of the most severe and prevalent non-communicable diseases worldwide, affecting an estimated one-third of the population in Spain.
- Conditions
- Obesity and Overweight, Obesity, Morbid, Metabolic Syndrome
- Trial name
- MicoBeBioticos (NCT06722443)
- Testing
- Probiotic, Prebiotic, Synbiotic
- Where
- Spain
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Allergic Rhinitis, Allergic Rhinitis (AR)
Effect of Combined Probiotics and Vitamin D on Symptoms of Allergic Rhinitis
The goal of this clinical trial is to learn if taking probiotics, vitamin D, or both together can help lower symptoms of allergic rhinitis (AR) and improve quality of life in adults.
- Trial name
- NCT07115342
- Testing
- Standard Allergic Rhinitis Treatment, Combined Vitamin D and Probiotics Supplementation
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
Irritable Bowel Disease
Effects of Fasting and Hydro Colon Therapy Plus Probiotics on GI Microbiota in Intolerances and Irritable Bowel Syndrome
Consequences of Colon Hydrotherapy plus probiotic intervention on composition of GI microbiota and well being are analysed in subjects claiming GI inconveniences due to Irritable Bowel Syndrome or food intolerances.
- Trial name
- MicFFGAH2013 (NCT02372201)
- Testing
- Hydro Colon Therapy plus probiotic
- Where
- Austria
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Vienna
Bacterial Vaginosis (BV)
Live Double Combined Lactobacillus Capsule for Vaginal Use（IIa）
This is a mutilcenter, randomized, double-blind, Metronidazole controlled phase lIa clinical study to evaluate the safety and tolerability of dual - live lactobacilli-containing vaginal capsules for the treatment of Bacterial…
- Trial name
- BV (NCT07418996)
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Guangdong Longchuangji Pharmaceutical Co., Ltd.
Otitis Media With Effusion, Healthy
The URT and Middle Ear Microbiota in Health and During Chronic OME
This study analyses which bacteria are present in the middle ear space and adjacent upper respiratory tract niches in healthy people and in patients suffering from chronic otitis media with effusion (OME; glue ear).
- Trial name
- NCT03109496
- Testing
- Collection of body fluids/swabs
- Where
- Belgium
- Volunteers
- 82 people
- Sponsor
- University Hospital, Antwerp