Clinical trials: Probiotics
Probiotic Intervention, Healthy Adult Participants
Early Probiotic Research: Open-label Functional Intervention and Longitudinal Evaluation in Healthy Adults
This study is a pre-post, open-label pilot feasibility study designed to investigate how a food-grade probiotic supplement affects biological measurements and wellbeing in healthy adults.
- Trial name
- ePROFILE20 (NCT07841457)
- Testing
- Probiotic Supplement (1C-01)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- OneCarbon
Cognition, Multiomics
Probiotic Research: Open-label Functional Intervention and Longitudinal Evaluation in Healthy Adults
This study is a pre-post, open-label cohort study designed to investigate how a food-grade probiotic supplement affects biological measurements and wellbeing in healthy adults.
- Conditions
- Cognition, Multiomics, Microbiome Analysis, Metabolome
- Trial name
- PROFILE (NCT07457242)
- Testing
- Probiotic Supplementation (Lactobacillus plantarum)
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- OneCarbon
Gastrointestinal Tolerance of Probiotics in Infants
Evaluating the Impact of Synbiotic Supplementation on Infants and Toddlers
Background and Significance: Bifidobacterium longum subspecies infantis (B. infantis) and other infant associated Bifidobacterium (such as Bifidobacterium longum subspecies longum and Bifidobacterium breve) are known to be…
- Trial name
- NCT06746285
- Testing
- Synbiotic Supplement
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Persephone Biosciences
Probiotic, Microbiome
Probiotics for Women
Investigation into the effect of probiotic supplementation on the wellbeing of women with a history of vaginal discomfort and/or irritation, along with any microbiome changes.
- Conditions
- Probiotic, Microbiome, Wellbeing
- Trial name
- NCT07364383
- Testing
- Lab4 + Lactobacillus gasseri and Lactobacillus crispatus
- Where
- Bulgaria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cultech Ltd
Common Cold, Immunity
Effects of LP28 on Immunity Enhancement in the Elderly
Due to the increasing attention on aging-related health issues, this study focuses on the elderly population as participants. The aim is to investigate whether supplementation with Lactobacillus plantarum LP28 can effectively…
- Conditions
- Common Cold, Immunity, Probiotic
- Trial name
- NCT06724185
- Testing
- LP28 capsule
- Where
- 2 sites in Taiwan
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Synbio Tech Inc.
Osteopenia, Osteoporosis
Food Trial Evaluating Fecal Abundance of SBD111 With Once-Daily Versus Twice-Daily Administration in Healthy Adults
The purpose of this study is to determine whether a modified formulation and daily intake schedule of SBD111 results in similar levels of probiotic microbes in the gut compared with the currently used formulation.
- Conditions
- Osteopenia, Osteoporosis, Menopause Related Conditions, Probiotic Intervention
- Trial name
- NCT07538167
- Testing
- SBD111(current formulation), SBD111 (new formulation)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Solarea Bio, Inc
Amino Acid Absorption, Probiotic
Changes in Amino Acid Absorption After Adding a Probiotic to an Acute Protein Feeding
The purpose of this study is to examine the rate and concentration of amino acid absorption after a three-week pattern of milk protein supplementation with and without the addition of a single strain probiotic.
- Trial name
- NCT06701604
- Testing
- Single Strain Probiotic + Milk Protein
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Probiotic Supplement
Growth, Safety and Efficacy of a Probiotic Supplement
The primary objective of the study is to demonstrate the safety of a daily high dose of a probiotic supplement by comparing the growth (weight gain, g/day) of formula-fed and/or breastfed infants in high dose group versus placebo…
- Trial name
- NCT04765852
- Testing
- High dose probiotic supplement, Low dose probiotic supplement
- Where
- Philippines
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Probiotics, Oral Health
Double-blind Clinical Trials of Probiotic Products in Oral Health.
In order to evaluate the effects of supplementary probiotics and their metabolites on oral environment and oral microbiota, Taiwan FDA No.
- Conditions
- Probiotics, Oral Health, Probiotic Metabolites
- Trial name
- NCT04289337
- Testing
- Combined probiotics (1), Combined probiotics (2), Combined heat-killed probiotics (1)
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Glac Biotech Co., Ltd
Healthy Response to Probiotics
Defining the Normal Human Response to Probiotics
The study is a mono-center, randomized, semi-blinded, placebo-controlled, cross-over, proof-of principle study in healthy volunteers. The study will determine the probiotic effect of LGG on intestinal tissue and intestinal cells
- Trial name
- NCT03140878
- Testing
- LGG
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Influenza Vaccination, Immune Response
Effects of Lactobacillus Coryniformis CECT5711 on Immune Response to Influenza Vaccination in Adults Over 65.
The objective of the present study is to evaluate the capability of the probiotic strain Lactobacillus coryniformis K8 CECT5711 (Lc K8) to enhance the immune response to influenza vaccine in elderly and the effect on respiratory…
- Conditions
- Influenza Vaccination, Immune Response, Probiotics
- Trial name
- NCT03167593
- Testing
- Lactobacillus coryniformis K8 CECT5711
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Effect of Probiotics on Infections in Infants.
Effect of 12-week Probiotic Supplementation on Bacterial and Viral Infections in Infants Aged 6 to 12 Months.
The purpose of this clinical trial is to evaluate the safety and effectiveness of 12-week probiotic supplementation on the incidence and duration of infectious episodes in infants aged 6 to 12 months.
- Trial name
- NCT01724203
- Testing
- Lactobacillus rhamnosus, Bifidobacterium animalis subsp. lactis
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre
Enhancement of Protective Antibody Response After Probiotic Consumption
Effect of a Mixture of Probiotics on the Antigen Specific Antibody Response in a Influenza Vaccination Model of Healthy Adults
the aim of the study is to get evidence for an enhancement of immune status in subjects after probiotics mixture consumption ( lactobacillus gasseri PA 16/8, Bifidobacterrium longum SP 07/3, Bifidobacterium bifidum MF 20/5) based…
- Trial name
- PROBIMMUNE (NCT01652066)
- Testing
- Mixture of probiotics, Mixture of probitiocs
- Where
- France
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Merck Medication Familiale