Clinical trials: Probiotics
Kidney Transplantation, Kidney Transplantation Recipients
Effect of Probiotics on Immunosuppressant Therapy in Kidney Transplant Recipients
People who receive a donor kidney must take drugs to prevent their bodies from attacking the new organ. These drugs are called immunosuppressants. Probiotics are beneficial microbes that support gut health.
- Trial name
- PITON (NCT07884084)
- Testing
- Probiotic formulation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Federico II University
Infantile Colic
Combined Probiotics is More Effective in the Treatment of Infantile Colic
All participants are randomized into 1 of 3 treatment arms, the mixture L acidophilus, B longum and B. bifidum group, Lactobacillus reuteri or placebo group.
- Trial name
- NCT03877458
- Testing
- L. acidophilus TYCA06, B. longum BLI-02 and B. bifidum VDD088, L. reuteri GL-104
- Where
- Taiwan
- Volunteers
- 99 people
- Sponsor
- China Medical University Hospital
Vaginal Microbiota, Microbiota
Effect of Hifas Intima Oral on Vaginal Microbiota in Healthy Women
The goal of this clinical trial was to learn whether the vaginal microbiota changed after healthy women aged 18 to 45 years took Hifas Intima, an oral food supplement, for 3 months.
- Conditions
- Vaginal Microbiota, Microbiota, Vaginal Microbiome
- Trial name
- NCT07715058
- Testing
- Hifas INTIMA Oral
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hifas da Terra S.L.
Clinical Infection, Microbial Colonization
Effect of Gut Microbiota and Fecal Inflammatory Marker on Childhood Gastroenteritis
Childhood gastroenteritis establishes gastrointestinal disease and increase the economic burden, and the pediatric population is especially vulnerable to these gastrointestinal infections.
- Conditions
- Clinical Infection, Microbial Colonization, Gastroenteritis, Inflammatory Response
- Trial name
- NCT03856138
- Where
- Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Antibiotic-associated Diarrhea
Effect of Lactobacillus Probiotic on Healthy Adults
Diarrhea is a common side effect of antibiotics; it may prolong hospital stay, increase the risk of other infections, develop into more serious forms of disease, and lead to premature discontinuation of the needed antibiotic.
- Trial name
- NCT00748748
- Testing
- Culturelle
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Fargo VA Medical Center
Chronic Periodontitis
Efficacy of INERSAN in Patients With Chronic Periodontitis as Adjunctive to Full Mouth Disinfection
The purpose of this study is to evaluate beneficial effects of probiotic Lactobacillus brevis CD2 tablets in addition to the primary treatment for patients with chronic periodontitis (Full Mouth Disinfection), at local level and…
- Trial name
- NCT01438333
- Testing
- lactobacillus brevis tablets
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- University of L'Aquila
Aflatoxicosis
Investigating the Effects of Probiotic Yoghurt on Reducing the Levels of Aflatoxin B1 Toxin Among the School Children in Eastern Kenya
We hypothesis that intake of probiotic yogurt reduces absorption of AFB1 in the gut and subsequently reduce AFM1 and aflatoxins adduct, the biomarker in human urine and blood respectively.
- Trial name
- NCT02041026
- Testing
- probiotic yoghurt
- Where
- Kenya
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Technical University of Kenya
PreDiabetes, Impaired Glucose Tolerance
Effect of Probiotics Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes.
Pre diabetes (PD) is a term that refers to alterations in blood glucose levels, including impaired fasting glucose (IFG), impaired glucose tolerance (IGT) or both, and increase in glycated hemoglobin (HbA1c), all this factors…
- Conditions
- PreDiabetes, Impaired Glucose Tolerance, Hyperglycemia, Resistance, Insulin
- Trial name
- NCT04341571
- Testing
- Probiotics, Metformin
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- University of Guadalajara
Very Low Birth Weight Infants
Efficacy of Multiple Strain Probiotics Reduces the Neurobehavioral Disorder in Premature Very Low Birth Weight Infants
The management protocols, clinical practices, equipment, infrastructure, and key personnel in NICU are unchanged during the study period.
- Trial name
- NCT03858816
- Testing
- Mixture probiotics
- Where
- Taiwan
- Sponsor
- China Medical University Hospital
Healthy Participants
Probiotics in Wellbeing
This study will investigate whether taking a probiotic supplement every day for 12 weeks can reduce low-level inflammation and improve wellbeing in generally healthy adults.
- Trial name
- NCT07840066
- Testing
- Probiotic Supplementation (Lactobacillus plantarum)
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Reading
Hypercholesterolemia
Efficacy of Cardioviva™ Probiotic Yogurt Formulation
Background: Several studies have reported limited or no reduction in serum lipid concentrations in response to probiotic formulations.
- Trial name
- NCT01185795
- Testing
- Cardioviva™ yogurt
- Volunteers
- 150 people
- Sponsor
- Micropharma Limited
Atopic Dermatitis
A Study of a Probiotic in Atopic Dermatitis
The aim of this study was to assess the clinical effect of Lactobacillus sakei supplementation in children with atopic dermatitis.
- Trial name
- NCT00893230
- Testing
- probiotic L sakei KCTC 10755BP
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Chungbuk National University
Otitis Media in Children, Cleft Palate Children
Respiratory Tract Microbiome and Probiotics in Children With Cleft Palate
Otitis media with effusion (OME) involves fluid accumulation in the middle ear without infection, sometimes causing discomfort and hearing loss in children.
- Trial name
- NCT06505330
- Testing
- Probactiol Baby
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University Hospital, Antwerp
Type 1 Diabetes, type1diabetes
Reducing Innate Inflammation in New Onset Type 1 Diabetes
This study aims to determine whether Lactiplantibacillus plantarum 299v (Lp299v) supplementation will reduce systemic inflammation and prolong residual beta cell function in individuals newly diagnosed with Type 1 diabetes.
- Conditions
- Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT04335656
- Testing
- Lactiplantibacillus plantarum
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Medical College of Wisconsin
Age-Related Muscle Weakness
Effect of Lactiplantibacillus Plantarum LM1001 on Muscle Strength in Older Adults
Purpose: This clinical trial aims to evaluate the efficacy and safety of Lactiplantibacillus plantarum LM1001 in improving muscle strength in older adults.
- Trial name
- NCT07538830
- Testing
- Lactiplantibacillus plantarum LM1001
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lactomason Co., Ltd.
Functional Constipation
Evaluation of the Efficacy of a New Specific Infant Formula in Case of Functional Constipation
This study aims to assess the clinical efficacy, safety and tolerance of a new formula containing a prebiotic and a mix of probiotics in the specific population of infants suffering from functional constipation through a…
- Trial name
- NCT05340712
- Testing
- new infant formula, Standard formula
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- United Pharmaceuticals
Constipation
The Effect of Milk Powder With Fiber and Probiotics on Digestive Habits and General Health Well-being of Selected Filipino Mothers.
In-Shape Nutritional Milk Powder is a nutritional milk powder containing fibers, probiotics and other nutrients. This study will focus on the effects of fiber and probiotics on digestive health and health well being in selected…
- Trial name
- NCT01862341
- Testing
- ANMUM In-Shape Nutritional Milk Powder for Active Mothers
- Where
- 4 sites in Philippines
- Volunteers
- 72 people
- Sponsor
- Fonterra Research Centre
Orthodontics, Dental Hygiene
Evaluation of the Effect of a Probiotic in Patients Undergoing Orthodontic Therapy
Orthodontic patients need supplementary oral hygiene tools in addition to professional oral hygiene. The aim of this study is to evaluate the effects of Bifidobacterium animalis subs.
- Conditions
- Orthodontics, Dental Hygiene, Gingivitis and Periodontal Diseases
- Trial name
- NCT06752330
- Testing
- Use of probiotics during oral hygiene at home
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Chronic Kidney Failure
Observational Study of Kibow Biotics in Chronic Kidney Failure Patients
A specifically formulated probiotic product comprised of defined and tested microbial strains may afford renoprotection in what has been generally called "Enteric DialysisTM".
- Trial name
- NCT01450657
- Testing
- Kibow Biotics/Renadyl
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Kibow Pharma
Healthy Infants
Characterization of the Gastrointestinal Microbiota in Newborn Infants
The BABIES study is a single-center, randomized, double-blinded, placebo-controlled study in newborns with a 4-week intervention period from birth to 28 days of life followed by a 2-week follow-up period (Figure 1).
- Trial name
- BABIES I (NCT06789484)
- Testing
- Probiotic
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital