Clinical trials: Procalcitonin
the Relationship Between Procalcitonin and 30-day Mortality in COVID Patients
Procalcitonin Level and the High Risk of Mortality in 30 Days in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Patient , Cases Series.
Background: Procalcitonin (PCT) is a biomarker that has been proposed as a helpful tool in inflammatory Clinique cases specially patient with pulmonary bacterienne infection .
- Trial name
- NCT05008016
- Where
- Morocco
- Volunteers
- 582 people
- Sponsor
- Mohammed VI University Hospital
Colorectal Cancer
Inflammation Biomarkers in the Diagnosis of Postoperative Infectious Complications in Colorectal Cancer Surgery
This is a longitudinal, single-center, prospective study to determine the efficiency of WBC Count, CRP, PCT, Neutrophil CD64 and Monocyte Human Leukocyte Antigen- DR in the diagnosis of postoperative infectious complications in…
- Trial name
- NCT03559335
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Community-Acquired Pneumonia (CAP), Pneumonia
Clinical Impact of Rapid Molecular Testing for Pathogens in Patients With Severe Acute Respiratory Illness : A Pragmatic Trial
Community-acquired pneumonia (CAP) is among the most common reasons for emergency department (ED) visits. A clear understanding of the likely pathogens is essential for the rapid institution of adequate antimicrobial therapy.
- Trial name
- CIRT-RMT-SARI (NCT06605352)
- Testing
- The BIOFIRE®FILMARRAY® Pneumonia Panel
- Where
- Taiwan
- Volunteers
- 800 people
- Sponsor
- National Taiwan University Clinical Trial Center
Antibiotic Resistant Infection, Critical Illness
CD64 and Antibiotics in Human Sepsis
The purpose of the study is to find out whether CD64 expression on neutrophils measured by a new bedside test (LeukoDx) within 30 minutes is associated with effective antibiotic therapy in critically ill adult patients at risk of…
- Conditions
- Antibiotic Resistant Infection, Critical Illness, SIRS, Sepsis
- Trial name
- CD64SEPLDX (NCT02922998)
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- University of Ulm
Sepsis
Procalcitonin-guided Treatment on Duration of Antibiotic Therapy and Cost in Septic Patients
This clinical trial is aimed to show a procalcitonin-guided treatment algorithm may shorten duration of antibiotic therapy safely and cost-effectively in sepsis patients of Korean ICU.
- Trial name
- PRODA (NCT02202941)
- Testing
- Procalcitonin guided treatment, Conventional treatment
- Where
- 4 sites in South Korea
- Volunteers
- 62 people
- Sponsor
- Seoul National University Hospital
Sepsis, Heart Failure
Impact of Clinical, Demographic and Laboratory Variables on Brain Natriuretic Peptide Levels
Brain natriuretic peptide (BNP) is involved in the regulation of blood pressure and fluid volume. It is used for the early diagnosis of heart failure (HF) in patients presenting to the emergency room with dyspnea.
- Trial name
- NCT01382394
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Rambam Health Care Campus
Burns
An Investigation of the Effect of Types of Catheters on Bloodstream Infection in Patients With Major Burns: Prediction With Procalcitonin and Prognosis
Bloodstream infections and catheter-related infections frequently occur in burn patients. It is important to correctly assess and manage these infections.
- Trial name
- NCT05581316
- Testing
- Patients' procalcitonin, thrombocyte, and leukocyte levels were assessed every other day for 4 weeks, beginning on the first day they were admitted to the burn center.
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hasan Kalyoncu University
Lower Respiratory Tract Infection
Procalcitonin and Lung Ultrasonography Guided Antibiotherapy in Emergency Departments
Acute respiratory infections are a common reason of attendance at emergency departments. It is also the main reason of unnecessary antibiotic prescription.
- Trial name
- PLUS-IS-LESS (NCT05463406)
- Testing
- The PLUS algorithm, Usual care
- Where
- 9 sites in Switzerland
- Volunteers
- 1,407 people
- Sponsor
- Dr Boillat-Blanco Noemie
Inhalation Pneumonia
PROcalcitonin Pneumonia / Pneumonitis Associated With ASPIration
There is actually no consensus in place defining for which patients with suspected inhalation pneumonia antibiotic treatment should be initiated and what the duration of this antibiotic treatment should be.
- Trial name
- PROPASPI (NCT02862314)
- Testing
- Blood sample
- Where
- France
- Volunteers
- 167 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Sepsis
Clinical Evaluation of e- Ab Sensor - Based Real-time Diagnosis of Serum Procalcitonin Level
The purpose of this study is to develop a real-time diagnostic technique with e- Ab sensor for serum PCT level measurement will offer a test with lower cost, and increase the applicability of serum Procalcitonin (PCT) level in…
- Trial name
- NCT01388114
- Testing
- Electrosensing Antibody Probe System (e- Ab sensing)
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
COVID-19 Infection, Parathyroid Gland
The Status of Parathyroid Hormone Secretion in Covid-19 Patients
COVID-19 infection causes a hypersensitive immune reaction and widespread inflammation in various organs of the body, especially through cytokines in the lungs.
- Conditions
- COVID-19 Infection, Parathyroid Gland, Parathyroid Hormone, Calcium
- Trial name
- NCT04662437
- Testing
- Venous blood was collected for biochemistry testing
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Respiratory Infections
Viral Testing and Biomarkers to Reduce Antibiotic Use for Respiratory Infections
This trial is a pilot study to determine the feasibility of a randomized clinical trial comparing a treatment algorithm consisting of a limited number of clinical parameters, rapid molecular viral diagnostics, and serum…
- Trial name
- NCT01907659
- Testing
- Release of test results
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Rochester
Community-acquired Pneumonia
Trial of Respiratory Infections in Children for Enhanced Diagnostics
The overall aim of the TREND study is to improve the differential diagnosis of bacterial and viral etiology in children below 5 years of age with clinical community acquired pneumonia.
- Trial name
- TREND (NCT03233516)
- Where
- Sweden
- Volunteers
- 376 people
- Sponsor
- Karolinska Institutet
Pleuritis, Pleural Empyema
Procalcitonin in Pleural Pleuritis
The purpose of this study is to determine pleural level of procalcitonin in differents situations of pleuritis.
- Trial name
- NCT01011881
- Testing
- pleural level of procalcitonin
- Where
- France
- Volunteers
- 34 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Sepsis
Procalcitonin to Guide Antibiotic Stop in Neurocritical Care Patients.
Antibiotic overconsumption has been considered as one of the major contributive factors of the emergence of multidrug resistant bacteria, a serious threat particularly in intensive care units.
- Trial name
- NCT03683693
- Testing
- Procalcitonin group
- Where
- Belgium
- Volunteers
- 132 people
- Sponsor
- General Hospital Groeninge
Healthy
Procalcitonin Test Reference Range Determination
Prospective, single-centre study in healthy volunteers to establish a reference range for the RAMP Procalcitonin (PCT) test. The primary objective of this study is to establish the reference range for measurement of PCT levels…
- Trial name
- PRO-H (NCT02591121)
- Where
- Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Response Biomedical Corp.
Neonatal Bacterial Infection
Value for Cord Blood Procalcitonin to Diagnose Early Neonatal Bacterial Infection
After birth, in the presence of risk factors for early neonatal bacterial infection (IBNP), the pediatrician must make a difficult decision quickly or not to prescribe additional examinations and / or hospitalize or not the…
- Trial name
- PCT_CORDON (NCT02858700)
- Testing
- dosage of the umbilical cord blood Procalcitonin for diagnosing of IBNP
- Where
- France
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Colorectal (Colon or Rectal) Cancer, STOMACH NEOPLASM
Perioperative Biomarkers in Colorectal and Gastric Cancer Surgery
This study aims to evaluate whether monitoring perioperative inflammatory and metabolic biomarkers can help identify postoperative complications early in adult patients undergoing colorectal or gastric cancer surgery.
- Trial name
- PERIO-BIO (NCT07881133)
- Testing
- Perioperative Biomarker-Guided Monitoring
- Where
- Romania
- Volunteers
- 320 people
- Sponsor
- Bucharest Emergency Hospital
Bacterial Infections
PROcalcitonin Reduce Antibiotic Treatments in Acute-Ill Patients (PRORATA)
The study is a prospective, randomized, controlled intervention trial conducted in 9 centers, comparing a conventional strategy versus a PCT-guided strategy to start or to discontinue antibiotics, in patients with suspected…
- Trial name
- PRORATA (NCT00472667)
- Testing
- Procalcitonin guided strategy
- Where
- France
- Volunteers
- 630 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Obstructive Pulmonary Disease
Comparison of a Serum PRO-CT Guided Treatment and the Recommended Antibiotic Treatment for COPD
Exacerbations of chronic obstructive pulmonary disease (COPD) are the first cause of admission to Pulmonary Department in Italy and worldwide.
- Trial name
- NCT01125098
- Testing
- PRO-CT values
- Where
- Italy
- Volunteers
- 183 people
- Sponsor
- University of Modena and Reggio Emilia