Clinical trials: Prognathism
Class I Malocclusion, Class II Div 1 Malocclusion
Assesment of Ethnic Bias in an Artificial Intelligence Based Orthodontic Diagnosis System
This study explores how artificial intelligence (AI) can be used in orthodontics, which is the area of dentistry that focuses on correcting jaw and bite problems.
- Conditions
- Class I Malocclusion, Class II Div 1 Malocclusion, Class II Division 2 Malocclusion, Class III Malocclusion
- Trial name
- NCT07162753
- Where
- Turkey (Türkiye)
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Class III Malocclusion
3D Printed Reverse Twin Block for Class III Malocclusion
This RCT aims to evaluate the effectiveness of a novel 3D printed reverse twin block appliance in the management of maxillary deficiency in growing patients having class III malocclusion.
- Trial name
- 3DRTB (NCT07710391)
- Testing
- 3D printed Reverse Twin Block appliance, Conventional Reverse Twin Block appliance
- Where
- Iraq
- Volunteers
- 30 people
- Sponsor
- University of Baghdad
Class III Malocclusion
Patient Specific Intraoral Inverted-L Osteotomy Modified With Inferior Alveolar Nerve Relocation in Corrective Mandibular Surgery
Bilateral sagittal split osteotomy (BSSO) is considered the main osteotomy design in corrective mandibular surgery, however abnormal anatomical configuration of the posterior mandible with rolled out inferior border and thin…
- Trial name
- NCT05397002
- Testing
- patient specific inverted L mandibular osteotomy modified with inferior alveolar nerve relocation
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Class III Malocclusion, Root Resorption
Determining the Presence of RAP in Orthognathic Patients and Its Effect on Root Resorption by Biomarkers
A prospective clinical trial to what extent inflammatory biomarkers are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular…
- Trial name
- RAP (NCT04823325)
- Testing
- Orthognathic Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Maxillofacial Abnormalities, Jaw Abnormalities
Digital Occlusal Wafer Versus Waferless Distal Segment Repositioning for BSSO in Skeletal Mandibular Deformities
Research studies continues to attempt testing modifications to refine the treatment protocols through computer assisted design or computer-generated surgical Wafer splints, have greatly revolutionized the incorporation of digital…
- Conditions
- Maxillofacial Abnormalities, Jaw Abnormalities, Prognathism, Retrognathia
- Trial name
- NCT05151042
- Testing
- wafer-less approach, Computer Guided orthognathic surgery using occlusal wafers
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Cairo University
Abnormalities, Jaw, Malocclusion, Angle Class III
First-In-Man Performance and Safety Evaluation of the CARLO® Device in Midface Osteotomies
The study product is a Cold Ablation Robot-guided Laser Osteotome (CARLO®) robotic surgery device. It is a device that removes hard tissue such as bone by means laser ablation - it is therefore an alternative to Piezo-Electric…
- Trial name
- NCT03901209
- Testing
- Mid-face osteotomy
- Where
- 4 sites in Austria, Germany and 1 more
- Volunteers
- 31 people
- Sponsor
- Advanced Osteotomy Tools (AOT) AG
Class III Malocclusion, Underbite
Effects of Class III Elastics on Stability of Orthopaedic Class III Correction
The purpose of this study is to evaluate the effects of adding elastics to orthodontic retainers on the stability of class III correction and whether it reduces the need for jaw surgery.
- Trial name
- NCT04911400
- Testing
- Upper-lower clear plastic retainers + Class III elastics, Upper-lower clear plastic retainers
- Where
- 2 sites in Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Sydney Local Health District
Heart Failure With Preserved Ejection Fraction, Prognathism
Effect of Bilirubin on Prognosis in Heart Failure With Preserved Ejection Fraction
Factors influencing the prognosis of patients with heart failure with preserved ejection fraction (HFpEF) have been extensively studied.
- Trial name
- NCT06379152
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Chongqing Medical University
Class I Malocclusion, Maxillary Prognathism
Nano Coated Orthodontic Miniscrews for en Mass Retraction of the Upper Arch
study will be directed to evaluate silver-hydroxyapatite nano-coated versus uncoated orthodontic miniscrews for en masse retraction of the upper anterior segment.
- Conditions
- Class I Malocclusion, Maxillary Prognathism, Orthodontic Tooth Movement
- Trial name
- NCT07521267
- Testing
- Silver nanoparticles, uncoated titanium miniscrews
- Where
- Egypt
- Volunteers
- 14 people
- Sponsor
- Al-Azhar University
Class III Malocclusion, Facemask
Evaluation of Treatment Outcomes of Interceptive Orthodontic Intervention for Class Iii Malocclusion Using Inclined Plane Appliance Combined With Variable Bracket Placement
Study Title: Evaluation of Treatment Outcomes of Interceptive Orthodontic Intervention for Class III Malocclusion Using Inclined Plane Appliance Combined With Variable Bracket Placement Objective: To evaluate the clinical and…
- Conditions
- Class III Malocclusion, Facemask, Inclined Plane Appliance
- Trial name
- NCT07581990
- Testing
- Inclined Plane Appliance Combined With Variable Bracket Placement
- Where
- Vietnam
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Can Tho University of Medicine and Pharmacy
Palatal Expansion Technique, Cleft Lip and Palate
MARPE in Patients With Cleft Lip and Palate
The objective of this randomized controlled study will be to evaluate the dental and skeletal effects of maxillary protraction with a facemask, associated with MARPE and Class III elastics in patients with unilateral cleft lip…
- Conditions
- Palatal Expansion Technique, Cleft Lip and Palate, Class III Malocclusion, Skeletal Malocclusion
- Trial name
- NCT04354116
- Testing
- Rapid maxillary expansion, Maxillary Protraction
- Where
- Brazil
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontifícia Universidade Católica de Minas Gerais
Class III Malocclusion
Treating Growing Patients With Mandibular Prognathism and Maxillary Constriction
This randomized controlled trial intends to test the efficacy of two treatment protocols in the correction of Class III malocclusion with maxillary constriction.
- Trial name
- NCT06762418
- Testing
- RMR+SME, BAIMT+RME
- Where
- 2 sites in Syria
- Volunteers
- 26 people
- Sponsor
- Damascus University
Malocclusion, Angle Class III, Crossbite (Anterior) (Posterior)
Comparison of Two Miniscrew Anchored Maxillary Protraction Protocols
This study evaluates the dentoskeletal effects produced by two maxillary protraction protocols in adolescent patients. Half of participants will be treated with a tooth-borne and tooth-bone-borne expanders as anchorage in the…
- Trial name
- NCT03712007
- Testing
- MAMP therapy with MARPE expander, MAMP therapy with Hyrax expander
- Where
- Brazil
- Volunteers
- 35 people
- Sponsor
- University of Sao Paulo
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Class II Division 1 Malocclusion, Maxillary Prognathism
Laser-assisted Flapless Corticotomy in Accelerating Canine Retraction
Erbium lasers have been suggested to accomplish corticotomy without flap reflection due to their attractive advantages. The current trial aimed to evaluate the efficacy of laser-assisted flapless corticotomy in accelerating…
- Conditions
- Class II Division 1 Malocclusion, Maxillary Prognathism, Protrusion, Incisor
- Trial name
- NCT04316403
- Testing
- Er:YAG laser
- Where
- Syria
- Volunteers
- 18 people
- Sponsor
- Damascus University
Class III Malocclusion, Dentofacial Anomalies, Including Malocclusion
Intraoral Device vs Facial Mask for Class III Treatment
The aim of this randomized controlled trail is to compare the efficacy of an intraoral device (the Carriere® Motion 3D™ Class III Appliance) with the facial mask for the early treatemnt of Class III malocclusion.
- Trial name
- NCT04387175
- Testing
- Carriere Motion 3D Class III Appliance, Facial mask
- Volunteers
- 32 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Malocclusion, Angle Class I, Malocclusion, Angle Class II
AI-Assisted Versus Conventional Orthodontic Diagnosis and Treatment Planning
This study compared an artificial intelligence-assisted orthodontic diagnostic workflow using WebCeph with a conventional clinician-based workflow.
- Conditions
- Malocclusion, Angle Class I, Malocclusion, Angle Class II, Malocclusion, Angle Class III
- Trial name
- AI-OrthoDx (NCT07690774)
- Where
- Yemen
- Volunteers
- 120 people
- Sponsor
- Ben Hafeed Dental Center
Malocclusion, Anxiety
Patient Education Before Orthognathic Surgery
To evaluate the effectiveness in the use of an educational material through: Assessment of knowledge about post-operative orthognathic surgery; assessing levels of anxiety with the survey of Anxiety Inventory-STATE-TRAIT…
- Conditions
- Malocclusion, Anxiety, Micrognathism, Prognathism
- Trial name
- NCT01803204
- Testing
- Booklet - Preoperative Educational
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- University of Sao Paulo
Mandible Prognathism, Mandibular Retrognathism
Evaluation of the Accuracy of Patient Specific Implant in Fixation of Mandibular Sagittal Split Osteotomy
Study was Conducted on Patients were need BSSO Using PSI for reposition and fixation
- Trial name
- BSSO (NCT07222904)
- Testing
- PSI
- Where
- Egypt
- Volunteers
- 8 people
- Sponsor
- Faculty of Dental Medicine for Girls
Orthognathic Surgical Procedures
Facial Conformation Meshes for Orthognathic Surgery
This study is a retrospective analysis that evaluates the accuracy of 3D soft tissue simulation in bimaxillary orthognathic surgery for Class III dentofacial deformities.
- Trial name
- FEU (NCT06893614)
- Where
- 2 sites in Egypt
- Volunteers
- 13 people
- Sponsor
- Ain Shams University